ATE362940T1 - Geladene verbindungen mit einer nukleinsäure- bindenden einheit sowie deren verwendungen - Google Patents

Geladene verbindungen mit einer nukleinsäure- bindenden einheit sowie deren verwendungen

Info

Publication number
ATE362940T1
ATE362940T1 AT01954573T AT01954573T ATE362940T1 AT E362940 T1 ATE362940 T1 AT E362940T1 AT 01954573 T AT01954573 T AT 01954573T AT 01954573 T AT01954573 T AT 01954573T AT E362940 T1 ATE362940 T1 AT E362940T1
Authority
AT
Austria
Prior art keywords
compounds
nucleic acid
acid binding
binding unit
charged compounds
Prior art date
Application number
AT01954573T
Other languages
English (en)
Inventor
Yigong Ge
Matthew Taylor
Eldon Baird
Heinz Moser
Roland W Burli
Original Assignee
Genesoft Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genesoft Inc filed Critical Genesoft Inc
Application granted granted Critical
Publication of ATE362940T1 publication Critical patent/ATE362940T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
AT01954573T 2000-03-16 2001-03-14 Geladene verbindungen mit einer nukleinsäure- bindenden einheit sowie deren verwendungen ATE362940T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18993000P 2000-03-16 2000-03-16

Publications (1)

Publication Number Publication Date
ATE362940T1 true ATE362940T1 (de) 2007-06-15

Family

ID=22699352

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01954573T ATE362940T1 (de) 2000-03-16 2001-03-14 Geladene verbindungen mit einer nukleinsäure- bindenden einheit sowie deren verwendungen

Country Status (11)

Country Link
US (2) US6555693B2 (de)
EP (1) EP1265921B1 (de)
JP (1) JP2003529609A (de)
KR (1) KR20030043785A (de)
CN (1) CN1427839A (de)
AT (1) ATE362940T1 (de)
AU (1) AU7681401A (de)
CA (1) CA2403537A1 (de)
DE (1) DE60128551D1 (de)
HK (1) HK1052190A1 (de)
WO (1) WO2001074898A2 (de)

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ATE362940T1 (de) * 2000-03-16 2007-06-15 Genesoft Inc Geladene verbindungen mit einer nukleinsäure- bindenden einheit sowie deren verwendungen
WO2002088119A1 (en) * 2001-04-26 2002-11-07 Genesoft Pharmaceuticals, Inc Halogen-substituted thienyl compounds
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AU2002312370A1 (en) * 2001-06-13 2002-12-23 Roland W. Burli Antipathogenic benzamide compounds
GB0130868D0 (en) 2001-12-24 2002-02-06 Univ Strathclyde New compounds
US7498349B2 (en) 2002-08-02 2009-03-03 Genesoft Pharmaceuticals, Inc. Biaryl compounds having anti-infective activity
US7265129B2 (en) * 2002-10-25 2007-09-04 Genesoft Pharmaceuticals, Inc. Anti-infective biaryl compounds
WO2004052304A2 (en) 2002-12-10 2004-06-24 Oscient Pharmaceuticals Corporation Antibacterial compounds having a (pyrrole carboxamide)-(benzamide)-(imidazole carboxamide) motif
US7691962B2 (en) * 2004-05-19 2010-04-06 Medarex, Inc. Chemical linkers and conjugates thereof
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FI3319936T3 (fi) 2015-07-12 2026-03-12 Hangzhou Dac Biotech Co Ltd Silloituslinkkereitä soluun sitoutuvien molekyylien konjugoimiseksi
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WO2018093579A1 (en) 2016-11-16 2018-05-24 Amgen Inc. Triazole phenyl compounds as agonists of the apj receptor
EP3541803B1 (de) 2016-11-16 2020-12-23 Amgen Inc. Triazolpyridylverbindungen als agonisten des apj-rezeptors
US11046680B1 (en) 2016-11-16 2021-06-29 Amgen Inc. Heteroaryl-substituted triazoles as APJ receptor agonists
WO2018093577A1 (en) 2016-11-16 2018-05-24 Amgen Inc. Cycloalkyl substituted triazole compounds as agonists of the apj receptor
EP3541802B1 (de) 2016-11-16 2025-01-01 Amgen Inc. Alkylsubstituierte triazolverbindungen als agonisten des apj-rezeptors
EP3541792B1 (de) 2016-11-16 2020-12-23 Amgen Inc. Triazol-furan-verbindungen als agonisten des apj-rezeptors
EP3704122B1 (de) 2017-11-03 2021-09-01 Amgen Inc. Fusionierte triazolagonisten des apj-rezeptors
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CN115362144A (zh) * 2020-03-27 2022-11-18 株式会社钟化 含酰胺键化合物的制造方法
JP2024541058A (ja) 2021-11-03 2024-11-06 ハンジョウ ディーエーシー バイオテック シーオー．，エルティディ． 抗体の特異的共役

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Also Published As

Publication number Publication date
US20020065227A1 (en) 2002-05-30
HK1052190A1 (zh) 2003-10-03
US6555693B2 (en) 2003-04-29
WO2001074898A2 (en) 2001-10-11
DE60128551D1 (de) 2007-07-05
KR20030043785A (ko) 2003-06-02
EP1265921A1 (de) 2002-12-18
WO2001074898A3 (en) 2003-01-16
WO2001074898A8 (en) 2002-04-11
JP2003529609A (ja) 2003-10-07
US20070105135A1 (en) 2007-05-10
CA2403537A1 (en) 2001-10-11
US7301037B2 (en) 2007-11-27
AU7681401A (en) 2001-10-15
EP1265921B1 (de) 2007-05-23
CN1427839A (zh) 2003-07-02

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