ATE363491T1 - Reinigung von antikörpern durch protein a und ionenaustauschromatographie - Google Patents

Reinigung von antikörpern durch protein a und ionenaustauschromatographie

Info

Publication number
ATE363491T1
ATE363491T1 AT04715906T AT04715906T ATE363491T1 AT E363491 T1 ATE363491 T1 AT E363491T1 AT 04715906 T AT04715906 T AT 04715906T AT 04715906 T AT04715906 T AT 04715906T AT E363491 T1 ATE363491 T1 AT E363491T1
Authority
AT
Austria
Prior art keywords
protein
antibodies
purification
ion exchange
exchange chromatography
Prior art date
Application number
AT04715906T
Other languages
English (en)
Inventor
Julian Bonnerjea
Anna Preneta
Original Assignee
Lonza Biologics Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9953825&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE363491(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lonza Biologics Plc filed Critical Lonza Biologics Plc
Application granted granted Critical
Publication of ATE363491T1 publication Critical patent/ATE363491T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B01D15/362—Cation-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B01D15/363—Anion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies from serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT04715906T 2003-02-28 2004-03-01 Reinigung von antikörpern durch protein a und ionenaustauschromatographie ATE363491T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0304576.2A GB0304576D0 (en) 2003-02-28 2003-02-28 Protein a chromatography

Publications (1)

Publication Number Publication Date
ATE363491T1 true ATE363491T1 (de) 2007-06-15

Family

ID=9953825

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04715906T ATE363491T1 (de) 2003-02-28 2004-03-01 Reinigung von antikörpern durch protein a und ionenaustauschromatographie

Country Status (9)

Country Link
US (3) US20060030696A1 (de)
JP (2) JP2007525412A (de)
KR (1) KR101200732B1 (de)
CN (1) CN100384874C (de)
AT (1) ATE363491T1 (de)
DE (1) DE602004006725T2 (de)
ES (1) ES2288252T3 (de)
GB (1) GB0304576D0 (de)
TW (1) TWI325428B (de)

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Also Published As

Publication number Publication date
US20060194953A1 (en) 2006-08-31
JP2007525412A (ja) 2007-09-06
CN100384874C (zh) 2008-04-30
JP5752558B2 (ja) 2015-07-22
KR101200732B1 (ko) 2012-11-13
ES2288252T3 (es) 2008-01-01
KR20050113617A (ko) 2005-12-02
TWI325428B (en) 2010-06-01
JP2012067108A (ja) 2012-04-05
TW200530265A (en) 2005-09-16
US7847071B2 (en) 2010-12-07
CN1771260A (zh) 2006-05-10
DE602004006725T2 (de) 2008-02-07
US20060030696A1 (en) 2006-02-09
GB0304576D0 (en) 2003-04-02
DE602004006725D1 (de) 2007-07-12
US20110040075A1 (en) 2011-02-17

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