ATE368669T1 - C-substituierte trizyklische isoxazolin derivate und deren verwendung als anti-depressiva - Google Patents

C-substituierte trizyklische isoxazolin derivate und deren verwendung als anti-depressiva

Info

Publication number: ATE368669T1
Authority: AT; Austria
Prior art keywords: depressants; substituted tricyclic; isoxazoline derivatives; tricyclic isoxazoline; derivatives
Prior art date: 2002-08-12

Application number

AT03787817T

Other languages

English (en)

Inventor

Jose Ignacio Andres-Gil

Jose Manuel Bartolome-Nebreda

Rosa Maria Alvarez-Escobar

Margaretha Bakker

Antonius Adrianus Hendr Megens

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-08-12

Filing date

2003-08-12

Publication date

2007-08-15

2003-08-12 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2007-08-15 Application granted granted Critical

2007-08-15 Publication of ATE368669T1 publication Critical patent/ATE368669T1/de

Links

239000000935 antidepressant agent Substances 0.000 title 1
229940005513 antidepressants Drugs 0.000 title 1
150000002547 isoxazolines Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Psychiatry (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Child & Adolescent Psychology (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AT03787817T 2002-08-12 2003-08-12 C-substituierte trizyklische isoxazolin derivate und deren verwendung als anti-depressiva ATE368669T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP02078322		2002-08-12

Publications (1)

Publication Number	Publication Date
ATE368669T1 true ATE368669T1 (de)	2007-08-15

Family

ID=31725449

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03787817T ATE368669T1 (de)	2002-08-12	2003-08-12	C-substituierte trizyklische isoxazolin derivate und deren verwendung als anti-depressiva

Country Status (15)

Country	Link
US (1)	US7465741B2 (de)
EP (1)	EP1537124B1 (de)
JP (1)	JP4681295B2 (de)
CN (1)	CN1329396C (de)
AR (1)	AR040967A1 (de)
AT (1)	ATE368669T1 (de)
AU (1)	AU2003262571B2 (de)
CA (1)	CA2494235C (de)
DE (1)	DE60315311T2 (de)
DK (1)	DK1537124T3 (de)
ES (1)	ES2290537T3 (de)
HK (1)	HK1080080A1 (de)
PT (1)	PT1537124E (de)
TW (1)	TW200409777A (de)
WO (1)	WO2004016621A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ536109A (en) *	2002-04-02	2006-06-30	Janssen Pharmaceutica Nv	Substituted amino isoxazoline derivatives and their use as anti-depressants
JP2008521771A (ja)	2004-11-26	2008-06-26	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	改良された抗精神病活性および抗不安症活性を有するイソキサゾリン−インドール誘導体
CN102786515B (zh) *	2012-04-13	2014-07-23	湖南大学	2-（2,2-二甲基-2,3-二氢苯并呋喃-5-基）吗啉及其制备方法与应用
CN112374984A (zh) *	2020-11-06	2021-02-19	苏州求索生物科技有限公司	一种2-溴-4-羟基苯甲醚的制备工艺

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2055011T3 (es) *	1988-09-19	1994-08-16	Akzo Nv	Un procedimiento para la preparacion de derivados de tetrahidronaftaleno e indano.
GB9318691D0 (en) *	1993-09-09	1993-10-27	Merck Sharp & Dohme	Therapeutic agents
US6080745A (en) *	1993-09-15	2000-06-27	Merck Sharp & Dohme Limited	Fused tricyclic heteroaromatic derivatives as dopamine receptor subtype ligands
CN1058492C (zh) *	1993-12-24	2000-11-15	三得利株式会社	苯并噻嗪衍生物
AU710059B2 (en) *	1996-01-05	1999-09-09	Aventis Pharmaceuticals Inc.	4,5-dihydronaphth(1,2-C)isoxazoles and derivatives thereof having CNS activity
US6187774B1 (en) *	1996-03-04	2001-02-13	Yoshitomi Pharmaceutical Industries, Ltd.	Fused heterocyclic compounds and pharmaceutical applications thereof
WO1997047601A1 (en) *	1996-06-11	1997-12-18	Yoshitomi Pharmaceutical Industries, Ltd.	Fused heterocyclic compounds and medicinal uses thereof
HUP0101475A3 (en) *	1998-06-19	2003-01-28	Lundbeck & Co As H	4,5,6 and 7-indole and indoline derivatives, their preparation and use
MXPA03007432A (es) *	2001-02-21	2003-11-18	Janssen Pharmaceutica Nv	Derivados de isoxazolinas y su uso como antidepresivos.
NZ536109A (en) *	2002-04-02	2006-06-30	Janssen Pharmaceutica Nv	Substituted amino isoxazoline derivatives and their use as anti-depressants
ATE387455T1 (de) *	2002-08-21	2008-03-15	Janssen Pharmaceutica Nv	C6- und c9-substituierte chromeno(4,3- c)isoxazoline und ihre verwendung als anti- depressiva

2003
- 2003-08-11 AR ARP030102900A patent/AR040967A1/es unknown
- 2003-08-11 TW TW092121939A patent/TW200409777A/zh unknown
- 2003-08-12 HK HK06100165.3A patent/HK1080080A1/zh unknown
- 2003-08-12 CA CA2494235A patent/CA2494235C/en not_active Expired - Fee Related
- 2003-08-12 WO PCT/EP2003/050374 patent/WO2004016621A1/en not_active Ceased
- 2003-08-12 AT AT03787817T patent/ATE368669T1/de not_active IP Right Cessation
- 2003-08-12 DK DK03787817T patent/DK1537124T3/da active
- 2003-08-12 US US10/524,197 patent/US7465741B2/en not_active Expired - Lifetime
- 2003-08-12 DE DE60315311T patent/DE60315311T2/de not_active Expired - Lifetime
- 2003-08-12 AU AU2003262571A patent/AU2003262571B2/en not_active Ceased
- 2003-08-12 CN CNB03819483XA patent/CN1329396C/zh not_active Expired - Fee Related
- 2003-08-12 JP JP2004528523A patent/JP4681295B2/ja not_active Expired - Fee Related
- 2003-08-12 PT PT03787817T patent/PT1537124E/pt unknown
- 2003-08-12 ES ES03787817T patent/ES2290537T3/es not_active Expired - Lifetime
- 2003-08-12 EP EP03787817A patent/EP1537124B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
CN1329396C (zh)	2007-08-01
AU2003262571A1 (en)	2004-03-03
AR040967A1 (es)	2005-04-27
ES2290537T3 (es)	2008-02-16
EP1537124A1 (de)	2005-06-08
DK1537124T3 (da)	2007-10-29
PT1537124E (pt)	2007-10-16
JP4681295B2 (ja)	2011-05-11
HK1080080A1 (zh)	2006-04-21
JP2005537304A (ja)	2005-12-08
DE60315311T2 (de)	2008-04-17
CA2494235A1 (en)	2004-02-26
DE60315311D1 (de)	2007-09-13
WO2004016621A1 (en)	2004-02-26
TW200409777A (en)	2004-06-16
AU2003262571B2 (en)	2009-02-12
US7465741B2 (en)	2008-12-16
CA2494235C (en)	2011-10-11
EP1537124B1 (de)	2007-08-01
US20050256119A1 (en)	2005-11-17
CN1675222A (zh)	2005-09-28

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Legal Events

Date

Code

Title

Description

2007-12-15

UEP

Publication of translation of european patent specification

Ref document number: 1537124

Country of ref document: EP

2010-05-15

REN

Ceased due to non-payment of the annual fee