ATE373009T1 - Verfahren zur vorbereitung von telithromycin - Google Patents

Verfahren zur vorbereitung von telithromycin

Info

Publication number: ATE373009T1
Authority: AT; Austria
Prior art keywords: formula; xiia; benzoyl; deoxy; imidazol
Prior art date: 2004-04-28

Application number

AT05775551T

Other languages

English (en)

Inventor

Suhas Sohani

Mandar Deodhar

Nishant Patel

Manish Patel

Mahesh Davadra

Vinodkumar Kansal

Original Assignee

Alembic Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-04-28

Filing date

2005-04-25

Publication date

2007-09-15

2005-04-25 Application filed by Alembic Ltd filed Critical Alembic Ltd

2007-09-15 Application granted granted Critical

2007-09-15 Publication of ATE373009T1 publication Critical patent/ATE373009T1/de

Links

238000000034 method Methods 0.000 title abstract 3
LJVAJPDWBABPEJ-PNUFFHFMSA-N telithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)[C@@H](C)C(=O)O[C@@H]([C@]2(OC(=O)N(CCCCN3C=C(N=C3)C=3C=NC=CC=3)[C@@H]2[C@@H](C)C(=O)[C@H](C)C[C@@]1(C)OC)C)CC)[C@@H]1O[C@H](C)C[C@H](N(C)C)[C@H]1O LJVAJPDWBABPEJ-PNUFFHFMSA-N 0.000 title 1
229960003250 telithromycin Drugs 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 4
KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical compound NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 abstract 3
125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 3
125000002962 imidazol-1-yl group Chemical group [*]N1C([H])=NC([H])=C1[H] 0.000 abstract 3
229960002626 clarithromycin Drugs 0.000 abstract 2
230000015572 biosynthetic process Effects 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Life Sciences & Earth Sciences (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT05775551T 2004-04-28 2005-04-25 Verfahren zur vorbereitung von telithromycin ATE373009T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IN491MU2004		2004-04-28

Publications (1)

Publication Number	Publication Date
ATE373009T1 true ATE373009T1 (de)	2007-09-15

Family

ID=35159987

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT05775551T ATE373009T1 (de)	2004-04-28	2005-04-25	Verfahren zur vorbereitung von telithromycin

Country Status (10)

Country	Link
US (1)	US20070260066A1 (de)
EP (1)	EP1742957B1 (de)
AT (1)	ATE373009T1 (de)
AU (1)	AU2005238313A1 (de)
CA (1)	CA2559281A1 (de)
DE (1)	DE602005002475T2 (de)
ES (1)	ES2294733T3 (de)
PL (1)	PL1742957T3 (de)
SI (1)	SI1742957T1 (de)
WO (1)	WO2005105821A2 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7601695B2 (en)	2003-03-10	2009-10-13	Optimer Pharmaceuticals, Inc.	Antibacterial agents
WO2007039914A2 (en) *	2005-10-06	2007-04-12	Alembic Limited	Novel polymorphs of telithromycin
WO2007049296A2 (en) *	2005-10-28	2007-05-03	Alembic Limited	Amorphous form of telithromycin
US20070167382A1 (en) *	2005-11-15	2007-07-19	Nina Finkelstein	Crystalline and amorphous forms of telithromycin
WO2007069264A2 (en) *	2005-12-15	2007-06-21	Alembic Limited	Reference standards for determining the purity of telithromycin and processes therefor
GB0600238D0 (en)	2006-01-06	2006-02-15	Sandoz Ag	Organic compounds
WO2008007388A1 (en) *	2006-07-12	2008-01-17	Alembic Limited	Novel process for the preparation of telithromycin
WO2008023383A1 (en) *	2006-08-25	2008-02-28	Alembic Limited	Novel process for the preparation of telithromycin
ES2306590B1 (es) *	2006-12-15	2009-08-07	Ercros Industrial,S .A.	Formas cristalinas i y ii de telitromicina.
ES2310121B1 (es) *	2007-04-19	2009-09-11	Ercros Industrial, S.A.	Nuevo proceso de sintesis de telitromicina.
WO2009053259A1 (en) *	2007-10-25	2009-04-30	Sandoz Ag	Process for the production of telithromycin
AU2008316830B2 (en)	2007-10-25	2016-03-17	Cempra Pharmaceuticals, Inc.	Process for the preparation of macrolide antibacterial agents
CN107854477A (zh)	2008-10-24	2018-03-30	森普拉制药公司	使用含三唑的大环内酯治疗抗性疾病的方法
US9937194B1 (en)	2009-06-12	2018-04-10	Cempra Pharmaceuticals, Inc.	Compounds and methods for treating inflammatory diseases
US9480679B2 (en)	2009-09-10	2016-11-01	Cempra Pharmaceuticals, Inc.	Methods for treating malaria, tuberculosis and MAC diseases
HRP20160168T1 (hr)	2010-03-22	2016-03-25	Cempra Pharmaceuticals Inc	Kristalne forme makrolida i njihova uporaba
BR112012029586A2 (pt)	2010-05-20	2016-08-02	Cempra Pharmaceuticals Inc	processos para preparar macrolídeos e cetolídeos e intermediários dos mesmos
KR20130120458A (ko)	2010-09-10	2013-11-04	셈프라 파마슈티컬스, 인크.	질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
WO2013148891A1 (en)	2012-03-27	2013-10-03	Cempra Pharmaceuticals, Inc.	Parenteral formulations for administering macrolide antibiotics
WO2014152326A1 (en)	2013-03-14	2014-09-25	Cempra Pharmaceuticals, Inc.	Methods for treating respiratory diseases and formulations therefor
AU2014233240B2 (en)	2013-03-15	2018-08-09	Cempra Pharmaceuticals, Inc.	Convergent processes for preparing macrolide antibacterial agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL99995A (en) *	1990-11-21	1997-11-20	Roussel Uclaf	Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
FR2719587B1 (fr) *	1994-05-03	1996-07-12	Roussel Uclaf	Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2732684B1 (fr) *	1995-04-06	1997-04-30	Roussel Uclaf	Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

2005
- 2005-04-25 AT AT05775551T patent/ATE373009T1/de not_active IP Right Cessation
- 2005-04-25 PL PL05775551T patent/PL1742957T3/pl unknown
- 2005-04-25 EP EP05775551A patent/EP1742957B1/de not_active Expired - Lifetime
- 2005-04-25 SI SI200530112T patent/SI1742957T1/sl unknown
- 2005-04-25 ES ES05775551T patent/ES2294733T3/es not_active Expired - Lifetime
- 2005-04-25 CA CA002559281A patent/CA2559281A1/en not_active Abandoned
- 2005-04-25 WO PCT/IN2005/000125 patent/WO2005105821A2/en not_active Ceased
- 2005-04-25 AU AU2005238313A patent/AU2005238313A1/en not_active Abandoned
- 2005-04-25 DE DE602005002475T patent/DE602005002475T2/de not_active Expired - Fee Related
- 2005-04-25 US US10/591,889 patent/US20070260066A1/en not_active Abandoned

Also Published As

Publication number	Publication date
DE602005002475T2 (de)	2008-05-29
WO2005105821A2 (en)	2005-11-10
EP1742957B1 (de)	2007-09-12
PL1742957T3 (pl)	2008-05-30
AU2005238313A1 (en)	2005-11-10
WO2005105821A3 (en)	2006-04-27
US20070260066A1 (en)	2007-11-08
EP1742957A2 (de)	2007-01-17
ES2294733T3 (es)	2008-04-01
CA2559281A1 (en)	2005-11-10
SI1742957T1 (sl)	2008-04-30
DE602005002475D1 (de)	2007-10-25

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Legal Events

Date	Code	Title	Description
2008-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties