ATE374816T1 - Verbesserte nukleinsäuren, welche für eine chimäre glycosyltransferase kodieren - Google Patents

Verbesserte nukleinsäuren, welche für eine chimäre glycosyltransferase kodieren

Info

Publication number
ATE374816T1
ATE374816T1 AT97932659T AT97932659T ATE374816T1 AT E374816 T1 ATE374816 T1 AT E374816T1 AT 97932659 T AT97932659 T AT 97932659T AT 97932659 T AT97932659 T AT 97932659T AT E374816 T1 ATE374816 T1 AT E374816T1
Authority
AT
Austria
Prior art keywords
nucleic acids
chimeric
acids encoding
glycosyl transferase
improved nucleic
Prior art date
Application number
AT97932659T
Other languages
English (en)
Inventor
Ian Mckenzie
Mauro Sandrin
Original Assignee
Austin Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AUPO1402A external-priority patent/AUPO140296A0/en
Application filed by Austin Research Inst filed Critical Austin Research Inst
Application granted granted Critical
Publication of ATE374816T1 publication Critical patent/ATE374816T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
AT97932659T 1996-08-02 1997-08-01 Verbesserte nukleinsäuren, welche für eine chimäre glycosyltransferase kodieren ATE374816T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPO1402A AUPO140296A0 (en) 1996-08-02 1996-08-02 Improved nucleic acids encoding a chimeric glycosyltransferase
US2427996P 1996-08-21 1996-08-21

Publications (1)

Publication Number Publication Date
ATE374816T1 true ATE374816T1 (de) 2007-10-15

Family

ID=25645233

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97932659T ATE374816T1 (de) 1996-08-02 1997-08-01 Verbesserte nukleinsäuren, welche für eine chimäre glycosyltransferase kodieren

Country Status (7)

Country Link
US (2) US7001998B2 (de)
EP (1) EP0874900B1 (de)
JP (1) JPH11512933A (de)
AT (1) ATE374816T1 (de)
CA (1) CA2233705A1 (de)
DE (1) DE69738177T2 (de)
WO (1) WO1998005768A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO182396A0 (en) * 1996-08-23 1996-09-12 Austin Research Institute, The Improved nucleic acids for reducing carbohydrate epitopes
DK1137789T3 (da) * 1998-12-09 2010-11-08 Phyton Holdings Llc Fremgangsmåde til fremstilling af et glycoprotein med glycosylering af human type
AU1099701A (en) * 1999-10-22 2001-05-08 University Of Pittsburgh Alpha1-3 galactosyltransferase gene and promoter
DE60044858D1 (de) * 1999-10-26 2010-09-30 Stichting Dienst Landbouwkundi Säugetierartige Glykosylierung in Pflanzen
US7449308B2 (en) 2000-06-28 2008-11-11 Glycofi, Inc. Combinatorial DNA library for producing modified N-glycans in lower eukaryotes
US7598055B2 (en) 2000-06-28 2009-10-06 Glycofi, Inc. N-acetylglucosaminyltransferase III expression in lower eukaryotes
US8697394B2 (en) 2000-06-28 2014-04-15 Glycofi, Inc. Production of modified glycoproteins having multiple antennary structures
ES2252261T3 (es) 2000-06-28 2006-05-16 Glycofi, Inc. Metodos para producir glicoproteinas modificadas.
US7863020B2 (en) 2000-06-28 2011-01-04 Glycofi, Inc. Production of sialylated N-glycans in lower eukaryotes
US7625756B2 (en) 2000-06-28 2009-12-01 GycoFi, Inc. Expression of class 2 mannosidase and class III mannosidase in lower eukaryotic cells
DK1356068T3 (en) 2001-01-19 2015-02-16 Phyton Holdings Llc PROCESS FOR THE PRODUCTION OF secretory glycoprotein with HUMAN TYPE SUGAR CHAIN ​​FOR USING A PLANT CELL
AU2002236234B2 (en) * 2001-03-06 2007-12-20 Phyton Holdings, LLC. Plant cell having animal-type sugar chain adding function
CN1665934B (zh) 2002-03-19 2010-05-26 国际植物研究所 GNTIII(UDP-N乙酰葡萄糖胺:β-D-甘露糖苷β(1,4)-N-乙酰葡萄糖胺基-转移酶III)在植物中的表达
CN101613705A (zh) * 2002-03-19 2009-12-30 国际植物研究所 在植物中优化聚糖生成
DK1534819T3 (da) 2002-08-21 2010-04-19 Revivicor Inc Griselignende dyr, som mangler enhver ekspression af funktionel alfa-1,3-galactosyltransferase
CL2003002461A1 (es) * 2002-11-27 2005-01-07 Dow Chemical Company Agroscien Inmunoglobulina que comprende al menos un glicano afucosilado, composicion que la contiene, secuencia nucleotidica y vector que la comprende, procedimiento para producir dicha inmunoglobulina en plantas.
JP4405736B2 (ja) 2003-01-31 2010-01-27 コニカミノルタホールディングス株式会社 データベースシステム
US7332299B2 (en) 2003-02-20 2008-02-19 Glycofi, Inc. Endomannosidases in the modification of glycoproteins in eukaryotes
CA2533259C (en) * 2003-07-21 2014-01-28 Lifecell Corporation Acellular tissue matrices made from galactose .alpha.-1,3-galactose-deficient tissue
WO2005047469A2 (en) * 2003-11-05 2005-05-26 University Of Pittsburgh PORCINE ISOGLOBOSIDE 3 SYNTHASE PROTEIN, cDNA, GENOMIC ORGANIZATION, AND REGULATORY REGION
AU2005223617A1 (en) * 2004-03-17 2005-09-29 Revivicor, Inc. Tissue products from animals lacking functional alpha 1,3 galactosyl transferase
ES2368267T3 (es) * 2006-05-24 2011-11-15 Universite De Provence (Aix-Marseille 1) Preparación y utilizaciones de las secuencias génicas codificantes de las glucosiltransferasas quiméricas con actividad de glucosilación optimizada.
WO2008125972A2 (en) 2007-04-17 2008-10-23 Plant Research International B.V. Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases
US9420770B2 (en) 2009-12-01 2016-08-23 Indiana University Research & Technology Corporation Methods of modulating thrombocytopenia and modified transgenic pigs
US9034280B2 (en) 2009-12-16 2015-05-19 General Electric Corporation High-throughput methods and systems for processing biological materials
CA2693752A1 (en) * 2010-02-18 2011-08-18 Mitsubishi Heavy Industries, Ltd. Handy terminal for wind turbine generator
US20140115728A1 (en) 2012-10-24 2014-04-24 A. Joseph Tector Double knockout (gt/cmah-ko) pigs, organs and tissues
WO2015066668A1 (en) 2013-11-04 2015-05-07 Lifecell Corporation Methods of removing alpha-galactose

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR950704497A (ko) * 1992-11-27 1995-11-20 베르너 발데크 글리코실트랜스퍼라제 활성을 가진 단백질(Proteins Having Glycosyltransferase Activity)
EP0689597A4 (de) * 1993-03-16 1998-10-21 Austin Research Inst VERWENDUNG VON SCHWEIN GAL-g(a)(1,3) GALAKTOSYLTRANSFERASE FÜR XENOGENE THERAPIEN
US6331658B1 (en) * 1993-04-20 2001-12-18 Integris Baptist Medical Center, Inc. Genetically engineered mammals for use as organ donors
WO1995034202A1 (en) * 1994-06-15 1995-12-21 Alexion Pharmaceuticals, Inc. Methods for reducing hyperacute rejection of xenografts

Also Published As

Publication number Publication date
EP0874900A4 (de) 2000-08-16
US20010055584A1 (en) 2001-12-27
US7001998B2 (en) 2006-02-21
CA2233705A1 (en) 1998-02-12
EP0874900B1 (de) 2007-10-03
JPH11512933A (ja) 1999-11-09
DE69738177T2 (de) 2008-07-03
US20070271621A1 (en) 2007-11-22
WO1998005768A1 (en) 1998-02-12
EP0874900A1 (de) 1998-11-04
DE69738177D1 (de) 2007-11-15

Similar Documents

Publication Publication Date Title
ATE374816T1 (de) Verbesserte nukleinsäuren, welche für eine chimäre glycosyltransferase kodieren
EP1005529A4 (de) Verfahren zur trocknung von kompetenten zellen
ATE455173T1 (de) Nucleinsäuremoleküle codierend ein verzweigungsenzym aus bakterien der gattung neisseria sowie verfahren zur herstellung von alpha-1,6-verzweigten alpha-1,4-glucanen
MY133377A (en) Anti-il-12 antibodies, compositions, methods and uses
DE60022313D1 (de) Alternansucrase-kodierende nukleinsäure moleküle
ATE184647T1 (de) Embryonische stammzelle zur herstellung von chimäre und transgen-ongulaten
ATE175238T1 (de) Methoden zur herstellung von transgenen pflanzen mit modifiziertem kohlenhydratgehalt
EP1190043A4 (de) Glykoprotein vi und dessen anwendungen
FI820075L (fi) Rekombination-dna-medel och foerfarande
ATE228565T1 (de) Nukleinsäure, expressionsvektor und zusammensetzungen zur identifizierung und herstellung von rekombinanten sialyltransferasen
FI941048A0 (fi) Geloniinipolypeptidin koodaavia DNA-sekvenssejä
ATE409235T1 (de) Verfahren zur herstellung von ascorbinsäurezwischenprodukten in wirtszellen
IL151746A0 (en) Renilla reniformis fluorescent proteins, nucleic acids encoding the fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items
ZA200704460B (en) Plants having improved growth characteristics and method for making the same
DK0418945T3 (da) Forgreningsenzym og dets anvendelse
ATE337336T1 (de) Nukleinsäuren, die für stichodactylidae chromoproteine kodieren
AU6177101A (en) In vitro evolution of nucleic acids and encoded polypeptide
EP1718739A4 (de) Verfahren zur rückfaltung von säuger-glycosyltransferasen
ATE296835T1 (de) Orotidin-5'-phosphatdecarboxylase-gen, genkonstrukt enthaltend dieses gen und seine verwendung
ATE522604T1 (de) Verfahren zur herstellung von proteinen durch elektropulsierung
DE60233347D1 (de) Schnellreifende fluoreszierende proteine und verfahren zu deren anwendung
DE60142785D1 (de) Verfahren zur herstellung von multifunktionellen lysyl hydroxylasen mit glycosyltransferaseaktivität
WO2000011168A3 (en) Genes that regulate hematopoietic blood forming stem cells and uses thereof
AR021842A1 (es) Un vector, un metodo para producir celulas transformadas, una celula transformada y metodo de expresion de un gen.
TR200002555T2 (tr) Bitki transformasyonu ve rejenerasyonu için yöntemler.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties