ATE377360T1 - Neuartige phytase - Google Patents

Neuartige phytase

Info

Publication number
ATE377360T1
ATE377360T1 AT98940861T AT98940861T ATE377360T1 AT E377360 T1 ATE377360 T1 AT E377360T1 AT 98940861 T AT98940861 T AT 98940861T AT 98940861 T AT98940861 T AT 98940861T AT E377360 T1 ATE377360 T1 AT E377360T1
Authority
AT
Austria
Prior art keywords
enzyme
phytasis
novel
phytate
phytase
Prior art date
Application number
AT98940861T
Other languages
English (en)
Inventor
Jay Short
Original Assignee
Verenium Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Verenium Corp filed Critical Verenium Corp
Application granted granted Critical
Publication of ATE377360T1 publication Critical patent/ATE377360T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/189—Enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/06—Enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/20—Removal of unwanted matter, e.g. deodorisation or detoxification
    • A23L5/25—Removal of unwanted matter, e.g. deodorisation or detoxification using enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
    • C12Y301/03026—4-Phytase (3.1.3.26), i.e. 6-phytase

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Animal Husbandry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fodder In General (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
AT98940861T 1997-08-13 1998-08-13 Neuartige phytase ATE377360T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/910,798 US5876997A (en) 1997-08-13 1997-08-13 Phytase

Publications (1)

Publication Number Publication Date
ATE377360T1 true ATE377360T1 (de) 2007-11-15

Family

ID=25429341

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98940861T ATE377360T1 (de) 1997-08-13 1998-08-13 Neuartige phytase

Country Status (10)

Country Link
US (3) US5876997A (de)
EP (3) EP1003379B1 (de)
JP (2) JP4194750B2 (de)
AT (1) ATE377360T1 (de)
AU (1) AU735371C (de)
CA (1) CA2300358C (de)
DE (1) DE69838676T2 (de)
DK (1) DK1003379T3 (de)
ES (1) ES2296341T3 (de)
WO (1) WO1999008539A1 (de)

Families Citing this family (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6309883B1 (en) 1994-02-17 2001-10-30 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5837458A (en) 1994-02-17 1998-11-17 Maxygen, Inc. Methods and compositions for cellular and metabolic engineering
AU743305C (en) 1997-01-17 2006-03-30 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
US6326204B1 (en) 1997-01-17 2001-12-04 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
US7148054B2 (en) * 1997-01-17 2006-12-12 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
US20040091968A1 (en) * 1997-08-13 2004-05-13 Short Jay M. Recombinant phytases and methods of making and using them
US6720014B1 (en) * 1997-08-13 2004-04-13 Diversa Corporation Phytase-containing foodstuffs and methods of making and using them
US6855365B2 (en) 1997-08-13 2005-02-15 Diversa Corporation Recombinant bacterial phytases and uses thereof
US7432097B2 (en) 1997-08-13 2008-10-07 Verenium Corporation Phytases, nucleic acids encoding them and methods of making and using them
US7078035B2 (en) 1997-08-13 2006-07-18 Diversa Corporation Phytases, nucleic acids encoding them and methods for making and using them
US6183740B1 (en) * 1997-08-13 2001-02-06 Diversa Corporation Recombinant bacterial phytases and uses thereof
US7390619B1 (en) * 1998-02-11 2008-06-24 Maxygen, Inc. Optimization of immunomodulatory properties of genetic vaccines
US6541011B2 (en) 1998-02-11 2003-04-01 Maxygen, Inc. Antigen library immunization
IL139093A0 (en) 1998-05-01 2001-11-25 Maxygen Inc Optimization of pest resistance genes using dna shuffling
US6451572B1 (en) 1998-06-25 2002-09-17 Cornell Research Foundation, Inc. Overexpression of phytase genes in yeast systems
EP1104459A1 (de) 1998-08-12 2001-06-06 Maxygen, Inc. Dna-shuffling von monooxygenase genen für die herstellung von industriellen chemikalien
BR9911681A (pt) * 1998-08-12 2001-10-02 Maxygen Inc Embaralhamento de dna para produzir culturas seletivas para herbicidas
US20060242731A1 (en) * 1998-08-12 2006-10-26 Venkiteswaran Subramanian DNA shuffling to produce herbicide selective crops
US6500639B2 (en) 1998-10-07 2002-12-31 Maxygen, Inc. DNA shuffling to produce nucleic acids for mycotoxin detoxification
EP1129184A1 (de) 1998-11-10 2001-09-05 Maxygen, Inc. Modifizierte adp-glukose pyrophosphorylase zur verbesserung und optimierung des phenotyps von pflanzen
US6438561B1 (en) * 1998-11-19 2002-08-20 Navigation Technologies Corp. Method and system for using real-time traffic broadcasts with navigation systems
WO2000042560A2 (en) 1999-01-19 2000-07-20 Maxygen, Inc. Methods for making character strings, polynucleotides and polypeptides
US6917882B2 (en) * 1999-01-19 2005-07-12 Maxygen, Inc. Methods for making character strings, polynucleotides and polypeptides having desired characteristics
US6376246B1 (en) 1999-02-05 2002-04-23 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US20030054390A1 (en) * 1999-01-19 2003-03-20 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US6436675B1 (en) 1999-09-28 2002-08-20 Maxygen, Inc. Use of codon-varied oligonucleotide synthesis for synthetic shuffling
US20070065838A1 (en) * 1999-01-19 2007-03-22 Maxygen, Inc. Oligonucleotide mediated nucleic acid recombination
US7024312B1 (en) * 1999-01-19 2006-04-04 Maxygen, Inc. Methods for making character strings, polynucleotides and polypeptides having desired characteristics
US6961664B2 (en) 1999-01-19 2005-11-01 Maxygen Methods of populating data structures for use in evolutionary simulations
JP2003524394A (ja) 1999-02-11 2003-08-19 マキシジェン， インコーポレイテッド ハイスループット質量分析法
JP3399518B2 (ja) * 1999-03-03 2003-04-21 インターナショナル・ビジネス・マシーンズ・コーポレーション 半導体構造およびその製造方法
CA2362737A1 (en) 1999-03-05 2000-09-08 Maxygen, Inc. Recombination of insertion modified nucleic acids
US6531316B1 (en) 1999-03-05 2003-03-11 Maxyag, Inc. Encryption of traits using split gene sequences and engineered genetic elements
EP1165806B1 (de) * 1999-03-31 2005-08-03 Cornell Research Foundation, Inc. Phospahatasen mit verbesserter phytase-aktivität
US7115795B1 (en) 1999-04-23 2006-10-03 University Of Guelph Transgenic animals expressing salivary proteins
AU4095800A (en) * 1999-04-23 2000-11-10 University Of Guelph Transgenic animals expressing salivary proteins
US6303766B1 (en) 1999-05-14 2001-10-16 Virginia Tech Intellectual Properties, Inc. Soybean phytase and nucleic acid encoding the same
WO2001004287A1 (en) * 1999-07-07 2001-01-18 Maxygen Aps A method for preparing modified polypeptides
US20040002474A1 (en) * 1999-10-07 2004-01-01 Maxygen Inc. IFN-alpha homologues
US7430477B2 (en) * 1999-10-12 2008-09-30 Maxygen, Inc. Methods of populating data structures for use in evolutionary simulations
US6841370B1 (en) 1999-11-18 2005-01-11 Cornell Research Foundation, Inc. Site-directed mutagenesis of Escherichia coli phytase
US6686515B1 (en) 1999-11-23 2004-02-03 Maxygen, Inc. Homologous recombination in plants
US7115712B1 (en) 1999-12-02 2006-10-03 Maxygen, Inc. Cytokine polypeptides
US20010039014A1 (en) * 2000-01-11 2001-11-08 Maxygen, Inc. Integrated systems and methods for diversity generation and screening
AU2001241939A1 (en) * 2000-02-28 2001-09-12 Maxygen, Inc. Single-stranded nucleic acid template-mediated recombination and nucleic acid fragment isolation
AU2001287273A1 (en) * 2000-03-24 2001-10-08 Maxygen, Inc. Methods for modulating cellular and organismal phenotypes
WO2001089317A2 (en) * 2000-05-25 2001-11-29 Diversa Corporation Dietary aids and methods of use thereof
AU2007201983B2 (en) * 2000-05-25 2011-12-01 Basf Enzymes Llc Recombinant bacterial phytases and uses thereof
AU2001272978A1 (en) 2000-06-23 2002-01-08 Maxygen, Inc. Novel co-stimulatory molecules
AU2001268716A1 (en) * 2000-06-23 2002-01-08 Maxygen, Inc. Novel chimeric promoters
AU2001271912A1 (en) * 2000-07-07 2002-01-21 Maxygen, Inc. Molecular breeding of transposable elements
US6858422B2 (en) * 2000-07-13 2005-02-22 Codexis, Inc. Lipase genes
US20020127623A1 (en) * 2000-07-31 2002-09-12 Maxygen, Inc. Biosensors, reagents and diagnostic applications of directed evolution
CA2421059A1 (en) * 2000-08-24 2002-02-28 Maxygen, Inc. Constructs and their use in metabolic pathway engineering
PT2335501T (pt) * 2001-10-31 2016-10-28 Huvepharma Ad Alimento animal contendo fitase e método
TW200305430A (en) * 2001-12-28 2003-11-01 Syngenta Participations Ag Thermotolerant phytase for animal feed
MY139056A (en) * 2001-12-28 2009-08-28 Ab Enzymes Gmbh Microbially-expressed thermotolerant phytase for animal feed
CA2495660A1 (en) * 2002-08-12 2004-02-19 Genencor International, Inc. Mutant e. coli appa phytase enzymes
DE60335497D1 (de) * 2002-09-13 2011-02-03 Cornell Res Foundation Inc Ergillus-phytasen
US7086750B2 (en) * 2003-06-23 2006-08-08 Se-Kure Controls, Inc. System for generating a message
WO2005014847A2 (en) * 2003-07-07 2005-02-17 Syngenta Participations Ag Reagents, methods and kits for detecting feed enzymes
US7009067B2 (en) * 2003-07-21 2006-03-07 Ip-6 Research, Inc. Hexa-citrated phytate and process of preparation thereof
US20050202447A1 (en) * 2004-03-11 2005-09-15 Surmodics, Inc. Array print buffers
DE202005021811U1 (de) * 2004-09-27 2010-04-15 Novozymes A/S Körnchen mit einem Kern und einer Beschichtung
DE102004050410A1 (de) 2004-10-15 2006-06-08 Ab Enzymes Gmbh Polypeptid mit Phytaseaktivität und dieses codierende Nucleotidsequenz
US7658922B2 (en) 2005-06-24 2010-02-09 Ab Enzymes Gmbh Monoclonal antibodies, hybridoma cell lines, methods and kits for detecting phytase
JP2009501024A (ja) * 2005-07-12 2009-01-15 テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション 癌の診断及び治療における遺伝的及びエピジェネティックな変化
PL3398606T3 (pl) 2006-01-19 2022-02-07 Algenist Holdings, Inc, Kompozycje otrzymane z mikroalg poprawiające zdrowie i wygląd skóry
US7919297B2 (en) * 2006-02-21 2011-04-05 Cornell Research Foundation, Inc. Mutants of Aspergillus niger PhyA phytase and Aspergillus fumigatus phytase
WO2008017066A2 (en) * 2006-08-03 2008-02-07 Cornell Research Foundation, Inc. Phytases with improved thermal stability
EP2051591B1 (de) 2006-08-07 2016-04-20 Novozymes A/S Enzymgranulat für tierfutter
US9578891B2 (en) 2006-08-07 2017-02-28 Novozymes A/S Enzyme granules for animal feed
HUE029140T2 (hu) 2006-09-21 2017-02-28 Basf Enzymes Llc Fitázok, ezeket kódoló nukleinsavak, valamint eljárások az elõállításukra és alkalmazásuk
US8192734B2 (en) 2007-07-09 2012-06-05 Cornell University Compositions and methods for bone strengthening
GB0922467D0 (en) * 2009-04-24 2010-02-03 Danisco Feed supplement
CN106011159A (zh) 2009-05-21 2016-10-12 巴斯夫酶有限责任公司 肌醇六磷酸酶、编码它们的核酸及制备和使用它们的方法
JP2015515259A (ja) 2012-02-07 2015-05-28 ダニスコ・ユーエス・インク フィターゼの安定化機構としてのグリコシル化
DK2811844T3 (da) 2012-02-07 2020-06-29 Danisco Us Inc Fremgangsmåde til forbedring af stabilitet af phytase med phytinsyre og sammensætninger, der omfatter phytase og phytinsyre
GB201308828D0 (en) 2013-03-12 2013-07-03 Verenium Corp Phytase
GB201308843D0 (en) 2013-03-14 2013-07-03 Verenium Corp Phytase formulation
AR095173A1 (es) 2013-07-25 2015-09-30 Basf Enzymes Llc Fitasa
WO2015197871A1 (en) 2014-06-27 2015-12-30 Dsm Ip Assets B.V. A method for improving the nutritional value of animal feed
US9528096B1 (en) * 2016-06-30 2016-12-27 Fornia Biosolutions, Inc. Phytases and uses thereof
US9605245B1 (en) 2016-06-30 2017-03-28 Fornia BioSoultions, Inc. Phytases and uses thereof
US10351832B2 (en) 2016-06-30 2019-07-16 Fornia Biosolutions, Inc. Phytases and uses thereof
KR102732756B1 (ko) 2018-05-08 2024-11-22 로커스 애그리컬쳐 아이피 컴퍼니 엘엘씨 식물 뿌리 및 면역 건강을 증진시키기 위한 미생물-기반 제품
JP7569523B2 (ja) 2018-11-20 2024-10-18 インターナショナル エヌアンドエイチ デンマーク エーピーエス 改変ロバスト高Ｔｍ－フィターゼ分岐群ポリペプチド及びその断片
WO2021173974A1 (en) 2020-02-28 2021-09-02 Dupont Nutrition Biosciences Aps Feed compositions
CN113652372B (zh) * 2021-08-30 2023-02-07 湖南师范大学 一株乳酸乳球菌及其在制备植酸酶和动物饲料中的应用
CN113812507A (zh) * 2021-09-27 2021-12-21 长春大学 一种以高低温豆粕为原料制备免消化大豆蛋白质的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5366736A (en) * 1989-02-16 1994-11-22 University Of Georgia Research Foundation, Inc. Vitamin D derivative feed compositions and methods of use
UA27702C2 (uk) * 1989-09-27 2000-10-16 Гіст-Брокейдс Н.В. Фрагмент геномної днк, що кодує фітазу aspergillus niger,фрагмент кднк, що кодує фітазу aspergillus niger, рекомбінантна плазмідна днк для експресії фітази в aspergillus (варіанти), штам aspergillus-продуцент фітази aspergillus (варіанти), спосіб одержання фітази, рекомбінанта фітаза aspergillus niger
KR0169913B1 (ko) * 1996-03-14 1999-01-15 김은영 신균주 바실러스속 ds11과 이로부터 생산되는 신규 파이타아제
US5939303A (en) * 1996-06-14 1999-08-17 Her Majesty The Queen In Right Of Canada, As Represented By The Dept. Of Agriculture & Agri-Food Canada Phytases of ruminal microorganisms
KR100206453B1 (ko) * 1997-03-27 1999-07-01 박원훈 신규한플라즈미드를이용하여형질전환시킨균주 이.채씨오엘아이.피와이로부터생산된피타제

Also Published As

Publication number Publication date
ES2296341T3 (es) 2008-04-16
CA2300358C (en) 2008-03-11
AU8904498A (en) 1999-03-08
EP1600505A1 (de) 2005-11-30
DE69838676D1 (de) 2007-12-20
US6110719A (en) 2000-08-29
EP1811020A1 (de) 2007-07-25
US6190897B1 (en) 2001-02-20
US5876997A (en) 1999-03-02
CA2300358A1 (en) 1999-02-25
DE69838676T2 (de) 2008-10-30
EP1003379A1 (de) 2000-05-31
WO1999008539A1 (en) 1999-02-25
JP2001514869A (ja) 2001-09-18
EP1003379B1 (de) 2007-11-07
EP1003379A4 (de) 2000-11-15
AU735371B2 (en) 2001-07-05
JP4194750B2 (ja) 2008-12-10
DK1003379T3 (da) 2008-03-25
JP2008099701A (ja) 2008-05-01
AU735371C (en) 2006-03-02

Similar Documents

Publication Publication Date Title
DE69838676D1 (de) Neuartige phytase
NZ333128A (en) Engineered human DNase I with DNA hydrolytic activity at least 50 percent greater than native human DNase I
MY127754A (en) Plasmid autonomously replicable in coryneform bacteria.
NZ503720A (en) Nucleotide sequences encoding ApoA-I agonists and their use in pharmaceutical compositions to treat dyslipidemic disorders such as cardiovascular disease
NO20024945D0 (no) Ekspresjonsregulerende sekvenser og ekspresjonsprodukter
AU2795292A (en) Synthetic dna sequence having enhanced insecticidal activity in maize
AU2001271786A1 (en) Interferon-like protein zcyto21
ATE284954T1 (de) Hyaluronan synthase gen und seine verwendung
ATE295414T1 (de) Menschliche ctla-8 und verwendung von ctla-8 ähnlichen proteinen
UA84666C2 (ru) ВЫДеЛЕНнЫЙ ПОЛИНУКЛЕОТИД, КОДИРУЮЩИЙ СЛИТОЙ ПРОТЕИН С ПЕСТИЦИДНОЙ АКТИВНОСТЬЮ, И ТРАНСГЕННАЯ КЛЕТКА-ХОЗЯИН
CY1106978T1 (el) Ενζυμα φωσφοδιεστερασης
NZ512835A (en) Genes identified as required for proliferation in escherichia coli
CA2252493A1 (en) .beta.-galactoside - .alpha. 2,6-sialyltransferase gene
GB9801408D0 (en) Frozen food product
EP1037999A4 (de) Porphorymonas gingivalis polypeptide und polynukleotide
DE69839178D1 (de) Gene, die für proteine mit transglykolysierungsaktivität kodieren.
ZA896980B (en) Peptide compounds
CA2253006A1 (en) .beta.-carotene hydroxylase gene
AUPN154295A0 (en) Nucleic acid molecule encoding a protein with avian gamma-interferon activity
GB9323225D0 (en) Novel plant enzyme
ATE286070T1 (de) Protein mit pflanzenschützenden eigenschaften
DK0828004T3 (da) Proteindisulfidisomerase-gen afledt af stamme af methylotrof gær
DE60015067D1 (de) Enzym mit Xylanaseaktivität
DE60036676D1 (de) G-protein-gekoppelter rezeptor-ähnliche proteine
EP1065269A4 (de) Für hm1.24 antigen kodierendes gen und dessen promotor

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1003379

Country of ref document: EP