ATE383848T1 - Formulierungen aus n-docosanol und saccharoseestern - Google Patents

Formulierungen aus n-docosanol und saccharoseestern

Info

Publication number: ATE383848T1
Authority: AT; Austria
Prior art keywords: docosanol; succarose; formulations; esters; sucrose
Prior art date: 1993-12-13

Application number

AT94927991T

Other languages

English (en)

Inventor

David H Katz

Mohammed H Khalil

John F Marcelletti

Laura E Pope

Lee R Katz

Original Assignee

Avanir Pharmaceuticals

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-12-13

Filing date

1994-09-02

Publication date

2008-02-15

1994-09-02 Application filed by Avanir Pharmaceuticals filed Critical Avanir Pharmaceuticals

2008-02-15 Application granted granted Critical

2008-02-15 Publication of ATE383848T1 publication Critical patent/ATE383848T1/de

Links

NOPFSRXAKWQILS-UHFFFAOYSA-N docosan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCO NOPFSRXAKWQILS-UHFFFAOYSA-N 0.000 title abstract 3
239000000203 mixture Substances 0.000 title abstract 2
150000002148 esters Chemical class 0.000 title 1
229930006000 Sucrose Natural products 0.000 abstract 2
-1 aliphatic alcohols Chemical class 0.000 abstract 2
239000005720 sucrose Substances 0.000 abstract 2
230000001225 therapeutic effect Effects 0.000 abstract 2
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
FOLJTMYCYXSPFQ-CJKAUBRRSA-N [(2r,3s,4s,5r,6r)-6-[(2s,3s,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)-2-(octadecanoyloxymethyl)oxolan-2-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl octadecanoate Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](COC(=O)CCCCCCCCCCCCCCCCC)O[C@@H]1O[C@@]1(COC(=O)CCCCCCCCCCCCCCCCC)[C@@H](O)[C@H](O)[C@@H](CO)O1 FOLJTMYCYXSPFQ-CJKAUBRRSA-N 0.000 abstract 1
229940071160 cocoate Drugs 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000006071 cream Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Dermatology (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

AT94927991T 1993-12-13 1994-09-02 Formulierungen aus n-docosanol und saccharoseestern ATE383848T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US16652393A	1993-12-13	1993-12-13

Publications (1)

Publication Number	Publication Date
ATE383848T1 true ATE383848T1 (de)	2008-02-15

Family

ID=22603672

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT04075956T ATE399004T1 (de)	1993-12-13	1994-09-02	Formulierungen aus c-20 bis c-28 alkoholen und saccharoseestern
AT94927991T ATE383848T1 (de)	1993-12-13	1994-09-02	Formulierungen aus n-docosanol und saccharoseestern

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT04075956T ATE399004T1 (de)	1993-12-13	1994-09-02	Formulierungen aus c-20 bis c-28 alkoholen und saccharoseestern

Country Status (14)

Country	Link
US (1)	US5534554A (de)
EP (2)	EP0738141B1 (de)
JP (2)	JP4149511B2 (de)
KR (1)	KR100322507B1 (de)
CN (2)	CN1103586C (de)
AT (2)	ATE399004T1 (de)
AU (1)	AU693476B2 (de)
CA (1)	CA2156063C (de)
DE (2)	DE69435067T2 (de)
DK (2)	DK0738141T3 (de)
ES (2)	ES2299173T3 (de)
PT (2)	PT738141E (de)
SG (1)	SG43833A1 (de)
WO (1)	WO1995016434A1 (de)

Families Citing this family (31)

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US6440980B1 (en) *	1996-09-17	2002-08-27	Avanir Pharmaceuticals	Synergistic inhibition of viral replication by long-chain hydrocarbons and nucleoside analogs
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AU780340B2 (en) *	1996-09-17	2005-03-17	Avanir Pharmaceuticals	Viral inhibition by long-chain alcohols, alkanes, fatty acids and amides
US5948822A (en)	1996-12-17	1999-09-07	Lidak Pharmaceuticals	Treatment of hyperproliferative skin disorders with C18 to C26 alphatic alcohols
EP1039885A1 (de) *	1996-12-17	2000-10-04	Lidak Pharmaceuticals	Verwendung von c18 bis c26-aliphatischen alkoholen zur herstellung eines medikaments für die behandlung von hyperproliferativen hauterkrankungen
DE19718777A1 (de) *	1997-05-03	1998-11-05	Beiersdorf Ag	Verwendung von Estern aus Fettsäuren und Di- und Oligosacchariden gegen die Adhäsion von Mikroorganismen
US6414028B1 (en)	1997-11-05	2002-07-02	Nexmed Holdings, Inc.	Topical compositions containing prostaglandin E1
US6046244A (en) *	1997-11-05	2000-04-04	Nexmed Holdings, Inc.	Topical compositions for prostaglandin E1 delivery
US20050203187A1 (en) *	1998-06-01	2005-09-15	Verbiscar Anthony J.	Formulations useful for the treatment of varicella zoster virus infections and methods for the use thereof
ITMI981528A1 (it) *	1998-07-03	2000-01-03	Recordati Ind Chimica E Farma	Formulazioni topiche di aciclovir
NZ506676A (en)	1999-09-03	2002-09-27	Thomas Harting	Recovery of pure sterols from black liquor soap skimmings or tall oil pitch
ATE384518T1 (de) *	2000-01-31	2008-02-15	Haerting S A	Zusammensetzungen enthaltend phytosterol- und policosanolester von fettsäuren zur herabsetzung des cholesterol- und triglyceridspiegels
PT102410A (pt) *	2000-02-03	2001-08-30	Qualitas Lab	Extraccao da fraccao ceroide do residuo resinoso de fabricacao de aglomerado negro de cortica com fluido supercritico
US7399790B2 (en)	2001-02-28	2008-07-15	Konowalchuk Thomas W	Virucidal compositions
EP1436006A4 (de) *	2001-10-16	2006-06-07	Avanir Pharmaceuticals	Virushemmung mit n-docosanol
US6559182B1 (en) *	2001-11-07	2003-05-06	Purcell Jojoba International, Llc	Method for treatment of enveloped viruses using jojoba oil esters
US7214394B2 (en) *	2002-05-31	2007-05-08	Archer-Daniels-Midland Company	Policosanol compositions, extraction from novel sources, and uses thereof
GB0313830D0 (en) *	2003-06-16	2003-07-23	Unichema Chemie Bv	Surfactant composition
US20050074443A1 (en) *	2003-10-03	2005-04-07	Treadwell Benjamin V.	Methods of attenuating autoimmune disease and compositions useful therefor
EP2132215B1 (de)	2007-02-28	2015-09-23	The Governors of the University of Alberta	Stoffe zur vorbeugung oder behandlung von viralen infektionen und deren verwendung
US8715715B2 (en)	2008-11-03	2014-05-06	Nal Pharmaceuticals Ltd.	Dosage form for insertion into the mouth
US20100209484A1 (en) *	2009-02-13	2010-08-19	Hoo-Kyun Choi	Transdermal Triptan Delivery System
FR2949329B1 (fr) *	2009-08-31	2011-10-21	Oreal	Composition cosmetique comprenant un alcane lineaire volatil et un ester de sucrose
CN102049050B (zh) *	2009-11-02	2014-06-18	重庆华邦制药有限公司	抗疱疹病毒感染的药物组合物
GB201207781D0 (en)	2012-05-03	2012-06-13	Restoration Of Appearance And Function Trust	Extracellular matrix - synthetic skin scaffold
CN103877019B (zh) *	2013-10-31	2016-01-06	湖北科益药业股份有限公司	一种二十二醇乳膏
EP4259068B1 (de) *	2020-12-14	2025-09-17	The Procter & Gamble Company	Verfahren zur herstellung kosmetischer zusammensetzungen, die sucroseester und lösungsmittel enthalten
WO2022132519A1 (en) *	2020-12-14	2022-06-23	The Procter & Gamble Company	Cosmetic compositions comprising sucrose esters and solvents
WO2024261713A1 (en)	2023-06-23	2024-12-26	Haleon UK IP Limited	Topical regimen for treating cold sores

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GB1459233A (en) *	1973-08-29	1976-12-22	Inst Rech Chim Biolog	Medicament containing a higher alkanol
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JPS63179817A (ja) *	1987-01-19	1988-07-23	Kobayashi Kooc:Kk	水性クレンジング料
US4900555A (en) *	1987-02-26	1990-02-13	Alza Corporation	Skin permeation enhancer compositions using sucrose esters
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US4865848A (en) *	1987-02-26	1989-09-12	Alza Corporation	Skin permeation enhancer compositions using sucrose esters
US5070107A (en) *	1989-04-28	1991-12-03	Lidak Pharmaceuticals	Systemic antiviral treatment
US4874794A (en) *	1989-04-28	1989-10-17	Lidak Biopharmaceuticals	Inflammatory disease treatment
US4956171A (en) *	1989-07-21	1990-09-11	Paco Pharmaceutical Services, Inc.	Transdermal drug delivery using a dual permeation enhancer and method of performing the same
US5166219A (en) *	1989-11-02	1992-11-24	Lidak Pharmaceuticals	Systemic anti-inflammatory treatment
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1994
- 1994-09-02 AT AT04075956T patent/ATE399004T1/de active
- 1994-09-02 JP JP51673895A patent/JP4149511B2/ja not_active Expired - Lifetime
- 1994-09-02 EP EP94927991A patent/EP0738141B1/de not_active Expired - Lifetime
- 1994-09-02 EP EP04075956A patent/EP1473031B1/de not_active Expired - Lifetime
- 1994-09-02 US US08/299,944 patent/US5534554A/en not_active Expired - Lifetime
- 1994-09-02 DE DE69435067T patent/DE69435067T2/de not_active Expired - Lifetime
- 1994-09-02 DE DE69435106T patent/DE69435106D1/de not_active Expired - Lifetime
- 1994-09-02 ES ES94927991T patent/ES2299173T3/es not_active Expired - Lifetime
- 1994-09-02 ES ES04075956T patent/ES2309441T3/es not_active Expired - Lifetime
- 1994-09-02 DK DK94927991T patent/DK0738141T3/da active
- 1994-09-02 CN CN94194951A patent/CN1103586C/zh not_active Expired - Lifetime
- 1994-09-02 CA CA002156063A patent/CA2156063C/en not_active Expired - Lifetime
- 1994-09-02 PT PT94927991T patent/PT738141E/pt unknown
- 1994-09-02 SG SG1996001710A patent/SG43833A1/en unknown
- 1994-09-02 PT PT04075956T patent/PT1473031E/pt unknown
- 1994-09-02 DK DK04075956T patent/DK1473031T3/da active
- 1994-09-02 AU AU77192/94A patent/AU693476B2/en not_active Expired
- 1994-09-02 WO PCT/US1994/009908 patent/WO1995016434A1/en not_active Ceased
- 1994-09-02 AT AT94927991T patent/ATE383848T1/de active
1996
- 1996-06-12 KR KR1019960703083A patent/KR100322507B1/ko not_active Expired - Lifetime
2002
- 2002-06-17 CN CNB021233632A patent/CN1223342C/zh not_active Expired - Lifetime
2006
- 2006-05-02 JP JP2006128264A patent/JP2006206610A/ja active Pending

Also Published As

Publication number	Publication date
CN1223342C (zh)	2005-10-19
DK0738141T3 (da)	2008-05-19
SG43833A1 (en)	1997-11-14
JP2006206610A (ja)	2006-08-10
DE69435067T2 (de)	2008-05-15
EP0738141A1 (de)	1996-10-23
EP0738141A4 (de)	1998-01-07
EP0738141B1 (de)	2008-01-16
US5534554A (en)	1996-07-09
JP4149511B2 (ja)	2008-09-10
EP1473031A1 (de)	2004-11-03
PT738141E (pt)	2008-02-11
PT1473031E (pt)	2008-08-05
JPH09506612A (ja)	1997-06-30
ES2299173T3 (es)	2008-05-16
DE69435106D1 (de)	2008-08-07
CN1419911A (zh)	2003-05-28
DK1473031T3 (da)	2008-10-20
ATE399004T1 (de)	2008-07-15
HK1056116A1 (en)	2004-02-06
ES2309441T3 (es)	2008-12-16
AU7719294A (en)	1995-07-03
CN1142764A (zh)	1997-02-12
AU693476B2 (en)	1998-07-02
CA2156063C (en)	1999-06-29
WO1995016434A1 (en)	1995-06-22
EP1473031B1 (de)	2008-06-25
DE69435067D1 (de)	2008-03-06
CN1103586C (zh)	2003-03-26
CA2156063A1 (en)	1995-06-22
KR100322507B1 (ko)	2002-08-14

Legal Events

Date

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2008-08-15

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Publication	Publication Date	Title
ATE383848T1 (de)	2008-02-15	Formulierungen aus n-docosanol und saccharoseestern
DE68921688D1 (de)	1995-04-20	Wenig reizendes Reinigungsmittel.
LV10965A (lv)	1995-12-20	Hialuronskabes asociatu (kompleksu) saturosu kompoziciju iegusanas panemiens
DE69004731D1 (de)	1994-01-05	Hilfsmittel enthaltende verdünnbare Formulierungen von Nachlaufherbiziden.
TR26646A (tr)	1995-03-15	Fluoroalkenil bilesikleri ve bunlarin zararlilari (pest'leri) kovucular olarak kullanimi
MA20648A1 (fr)	1986-10-01	Tensioactifs derives de l'acide citrique
MX9205725A (es)	1993-04-01	Formulaciones generantes de gas no azidico
FR2570778B1 (fr)	1991-05-17	Accouplement d'arbres a forte elasticite
DE69207353D1 (de)	1996-02-15	Ejektorreihe
FR2593966B1 (fr)	1988-09-09	Structure semi-conductrice monolithique d'un transistor bipolaire a heterojonction et d'un laser
FI951499L (fi)	1995-03-29	Kiniinihapon synteesi glukoosista
LV11463A (lv)	1996-08-20	Aizvietotu 4,6-diamino-5-cianpirimidinu iegusanas panemiens
TR26525A (tr)	1994-04-22	PIROTROID ISOMOLERININ DAHA AKTIF TüRLERE DÖNüSTüRüLMESI
FR2609463B1 (fr)	1990-11-30	Synthese des perfluoroalkyl-2 ethanethiols
IT8547769A1 (it)	1986-09-05	Dispositivo per le applicazioni di diserbanti alle piante
IT8454041V0 (it)	1984-11-14	Perfezionamenti ai meccanismi per il movimento delle estremita dei burattini
MX9205491A (es)	1993-05-01	Sintesis regioselectiva de agentes anti-inflamatorios de 1,5-diaril pirazol
DE3855050D1 (de)	1996-04-04	Synthese von Supraleitern aus Xenotim
LV5617A3 (lv)	1994-05-10	Aziridin-2-karbonskabes esteru iegusanas panemiens
DE69200523D1 (de)	1994-11-17	Polyglukosiden aus Hydroxyalkylsorbit.
IT8521232V0 (it)	1985-03-25	Composizioni antistress conattivita' biostimolante per piante.
IT8521233V0 (it)	1985-03-25	Composizioni antistress conattivita' biostimolante per piante.
IT8521231V0 (it)	1985-03-25	Composizioni antistress conattivita' biostimolante per piante.
IT8521234V0 (it)	1985-03-25	Composizioni antistress conattivita' biostimolante per piante.
LV5520A3 (lv)	1994-03-10	1,1-diokso-6-hlor-4-oksi-2-metil-N-(2-piridil)-2H-tieno-Ú2,3-e¾tiazin-3-karbonskabes amidu enola esteru iegusanas panemiens