DK0738141T3 - Sucroseester- og n-docosanolformuleringer - Google Patents

Sucroseester- og n-docosanolformuleringer

Info

Publication number: DK0738141T3
Authority: DK; Denmark
Prior art keywords: sucrose ester; docosanol; sucrose; formulations; docosanol formulations
Prior art date: 1993-12-13

Application number

DK94927991T

Other languages

English (en)

Inventor

David H Katz

Mohammed H Khalil

John F Marcelletti

Laura E Pope

Lee R Katz

Original Assignee

Avanir Pharmaceuticals

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-12-13

Filing date

1994-09-02

Publication date

2008-05-19

1994-09-02 Application filed by Avanir Pharmaceuticals filed Critical Avanir Pharmaceuticals

2008-05-19 Application granted granted Critical

2008-05-19 Publication of DK0738141T3 publication Critical patent/DK0738141T3/da

Links

NOPFSRXAKWQILS-UHFFFAOYSA-N docosan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCO NOPFSRXAKWQILS-UHFFFAOYSA-N 0.000 title abstract 4
229930006000 Sucrose Natural products 0.000 title abstract 3
-1 Sucrose ester Chemical class 0.000 title abstract 3
239000005720 sucrose Substances 0.000 title abstract 3
239000000203 mixture Substances 0.000 title abstract 2
238000009472 formulation Methods 0.000 title 1
230000001225 therapeutic effect Effects 0.000 abstract 2
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
FOLJTMYCYXSPFQ-CJKAUBRRSA-N [(2r,3s,4s,5r,6r)-6-[(2s,3s,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)-2-(octadecanoyloxymethyl)oxolan-2-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methyl octadecanoate Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](COC(=O)CCCCCCCCCCCCCCCCC)O[C@@H]1O[C@@]1(COC(=O)CCCCCCCCCCCCCCCCC)[C@@H](O)[C@H](O)[C@@H](CO)O1 FOLJTMYCYXSPFQ-CJKAUBRRSA-N 0.000 abstract 1
229940071160 cocoate Drugs 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000006071 cream Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Dermatology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Oil, Petroleum & Natural Gas (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Virology (AREA)
Bioinformatics & Cheminformatics (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

DK94927991T 1993-12-13 1994-09-02 Sucroseester- og n-docosanolformuleringer DK0738141T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US16652393A	1993-12-13	1993-12-13
PCT/US1994/009908 WO1995016434A1 (en)	1993-12-13	1994-09-02	Sucrose ester c-20 to c-28 alcohol formulations

Publications (1)

Publication Number	Publication Date
DK0738141T3 true DK0738141T3 (da)	2008-05-19

Family

ID=22603672

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK04075956T DK1473031T3 (da)	1993-12-13	1994-09-02	Sucroseester - C20 til C28 alkoholformuleringer
DK94927991T DK0738141T3 (da)	1993-12-13	1994-09-02	Sucroseester- og n-docosanolformuleringer

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK04075956T DK1473031T3 (da)	1993-12-13	1994-09-02	Sucroseester - C20 til C28 alkoholformuleringer

Country Status (14)

Country	Link
US (1)	US5534554A (da)
EP (2)	EP0738141B1 (da)
JP (2)	JP4149511B2 (da)
KR (1)	KR100322507B1 (da)
CN (2)	CN1103586C (da)
AT (2)	ATE399004T1 (da)
AU (1)	AU693476B2 (da)
CA (1)	CA2156063C (da)
DE (2)	DE69435106D1 (da)
DK (2)	DK1473031T3 (da)
ES (2)	ES2309441T3 (da)
PT (2)	PT738141E (da)
SG (1)	SG43833A1 (da)
WO (1)	WO1995016434A1 (da)

Families Citing this family (31)

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US5952392A (en) *	1996-09-17	1999-09-14	Avanir Pharmaceuticals	Long-chain alcohols, alkanes, fatty acids and amides in the treatment of burns and viral inhibition
AU780340B2 (en) *	1996-09-17	2005-03-17	Avanir Pharmaceuticals	Viral inhibition by long-chain alcohols, alkanes, fatty acids and amides
US6440980B1 (en) *	1996-09-17	2002-08-27	Avanir Pharmaceuticals	Synergistic inhibition of viral replication by long-chain hydrocarbons and nucleoside analogs
US5948822A (en)	1996-12-17	1999-09-07	Lidak Pharmaceuticals	Treatment of hyperproliferative skin disorders with C18 to C26 alphatic alcohols
EP1039885A1 (en) *	1996-12-17	2000-10-04	Lidak Pharmaceuticals	Use of c18 to c26 aliphatic alcohols for the manufacture of a medicament in the treatment of hyperproliferative skin disorders
DE19718777A1 (de) *	1997-05-03	1998-11-05	Beiersdorf Ag	Verwendung von Estern aus Fettsäuren und Di- und Oligosacchariden gegen die Adhäsion von Mikroorganismen
US6046244A (en) *	1997-11-05	2000-04-04	Nexmed Holdings, Inc.	Topical compositions for prostaglandin E1 delivery
US6414028B1 (en)	1997-11-05	2002-07-02	Nexmed Holdings, Inc.	Topical compositions containing prostaglandin E1
US20050203187A1 (en) *	1998-06-01	2005-09-15	Verbiscar Anthony J.	Formulations useful for the treatment of varicella zoster virus infections and methods for the use thereof
ITMI981528A1 (it) *	1998-07-03	2000-01-03	Recordati Ind Chimica E Farma	Formulazioni topiche di aciclovir
ES2242582T3 (es)	1999-09-03	2005-11-16	Cabby Business Inc.	Procedimiento de alta eficiencia para la preparacion de esteroles de alta pureza.
DK1121928T3 (da) *	2000-01-31	2008-03-17	Haerting S A	Sammensætninger indeholdende phytosterol- og policosanolestere af fedtsyrer til reduktion af niveauet af blodcholesterol og -triglycerider
PT102410A (pt) *	2000-02-03	2001-08-30	Qualitas Lab	Extraccao da fraccao ceroide do residuo resinoso de fabricacao de aglomerado negro de cortica com fluido supercritico
US7399790B2 (en) *	2001-02-28	2008-07-15	Konowalchuk Thomas W	Virucidal compositions
PL371945A1 (en) *	2001-10-16	2005-07-11	Avanir Pharmacueticals	Viral inhibition by n-docosanol
US6559182B1 (en) *	2001-11-07	2003-05-06	Purcell Jojoba International, Llc	Method for treatment of enveloped viruses using jojoba oil esters
US7214394B2 (en) *	2002-05-31	2007-05-08	Archer-Daniels-Midland Company	Policosanol compositions, extraction from novel sources, and uses thereof
GB0313830D0 (en) *	2003-06-16	2003-07-23	Unichema Chemie Bv	Surfactant composition
US20050074443A1 (en) *	2003-10-03	2005-04-07	Treadwell Benjamin V.	Methods of attenuating autoimmune disease and compositions useful therefor
PL2132215T3 (pl)	2007-02-28	2016-04-29	Univ Alberta	Związki do zapobiegania lub leczenia zakażeń wirusowych i sposoby ich stosowania
US8715715B2 (en)	2008-11-03	2014-05-06	Nal Pharmaceuticals Ltd.	Dosage form for insertion into the mouth
US20100209484A1 (en) *	2009-02-13	2010-08-19	Hoo-Kyun Choi	Transdermal Triptan Delivery System
FR2949329B1 (fr) *	2009-08-31	2011-10-21	Oreal	Composition cosmetique comprenant un alcane lineaire volatil et un ester de sucrose
CN102049050B (zh) *	2009-11-02	2014-06-18	重庆华邦制药有限公司	抗疱疹病毒感染的药物组合物
GB201207781D0 (en) *	2012-05-03	2012-06-13	Restoration Of Appearance And Function Trust	Extracellular matrix - synthetic skin scaffold
CN103877019B (zh) *	2013-10-31	2016-01-06	湖北科益药业股份有限公司	一种二十二醇乳膏
JP7715804B2 (ja) *	2020-12-14	2025-07-30	ザプロクターアンドギャンブルカンパニー	スクロースエステル及び溶媒を含む化粧品組成物
EP4259068B1 (en) *	2020-12-14	2025-09-17	The Procter & Gamble Company	Method of manufacturing cosmetic compositions comprising sucrose esters and solvents
EP4731182A1 (en)	2023-06-23	2026-04-29	Haleon UK IP Limited	Topical regimen for treating cold sores

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GB1459233A (en) *	1973-08-29	1976-12-22	Inst Rech Chim Biolog	Medicament containing a higher alkanol
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FR2492829A1 (fr) *	1980-10-24	1982-04-30	Oreal	Agents de surface non-ioniques derives du glucose, procede pour les preparer et compositions les contenant
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DE3318989C2 (de) *	1982-05-28	1996-11-21	Eisai Co Ltd	ß,gamma-Dihydropolyprenylalkoholderivate und diese enthaltende Arzneimittel und deren Verwendung
EP0158108B1 (en) *	1984-03-05	1992-10-14	Tonfer Inc.	Detergent composition
US4684479A (en) *	1985-08-14	1987-08-04	Arrigo Joseph S D	Surfactant mixtures, stable gas-in-liquid emulsions, and methods for the production of such emulsions from said mixtures
JPH0816066B2 (ja) *	1986-07-18	1996-02-21	エーザイ株式会社	持続性薬効製剤
JPS63179817A (ja) *	1987-01-19	1988-07-23	Kobayashi Kooc:Kk	水性クレンジング料
US4940586A (en) *	1987-02-26	1990-07-10	Alza Corporation	Skin permeation enhancer compositions using sucrose esters
US4900555A (en) *	1987-02-26	1990-02-13	Alza Corporation	Skin permeation enhancer compositions using sucrose esters
US4865848A (en) *	1987-02-26	1989-09-12	Alza Corporation	Skin permeation enhancer compositions using sucrose esters
US4874794A (en) *	1989-04-28	1989-10-17	Lidak Biopharmaceuticals	Inflammatory disease treatment
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US5166219A (en) *	1989-11-02	1992-11-24	Lidak Pharmaceuticals	Systemic anti-inflammatory treatment
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1994
- 1994-09-02 AT AT04075956T patent/ATE399004T1/de active
- 1994-09-02 ES ES04075956T patent/ES2309441T3/es not_active Expired - Lifetime
- 1994-09-02 PT PT94927991T patent/PT738141E/pt unknown
- 1994-09-02 DE DE69435106T patent/DE69435106D1/de not_active Expired - Lifetime
- 1994-09-02 CA CA002156063A patent/CA2156063C/en not_active Expired - Lifetime
- 1994-09-02 WO PCT/US1994/009908 patent/WO1995016434A1/en not_active Ceased
- 1994-09-02 DK DK04075956T patent/DK1473031T3/da active
- 1994-09-02 AU AU77192/94A patent/AU693476B2/en not_active Expired
- 1994-09-02 US US08/299,944 patent/US5534554A/en not_active Expired - Lifetime
- 1994-09-02 ES ES94927991T patent/ES2299173T3/es not_active Expired - Lifetime
- 1994-09-02 EP EP94927991A patent/EP0738141B1/en not_active Expired - Lifetime
- 1994-09-02 DK DK94927991T patent/DK0738141T3/da active
- 1994-09-02 PT PT04075956T patent/PT1473031E/pt unknown
- 1994-09-02 JP JP51673895A patent/JP4149511B2/ja not_active Expired - Lifetime
- 1994-09-02 SG SG1996001710A patent/SG43833A1/en unknown
- 1994-09-02 AT AT94927991T patent/ATE383848T1/de active
- 1994-09-02 DE DE69435067T patent/DE69435067T2/de not_active Expired - Lifetime
- 1994-09-02 CN CN94194951A patent/CN1103586C/zh not_active Expired - Lifetime
- 1994-09-02 EP EP04075956A patent/EP1473031B1/en not_active Expired - Lifetime
1996
- 1996-06-12 KR KR1019960703083A patent/KR100322507B1/ko not_active Expired - Lifetime
2002
- 2002-06-17 CN CNB021233632A patent/CN1223342C/zh not_active Expired - Lifetime
2006
- 2006-05-02 JP JP2006128264A patent/JP2006206610A/ja active Pending

Also Published As

Publication number	Publication date
CN1103586C (zh)	2003-03-26
ES2299173T3 (es)	2008-05-16
EP1473031B1 (en)	2008-06-25
KR100322507B1 (ko)	2002-08-14
ATE399004T1 (de)	2008-07-15
US5534554A (en)	1996-07-09
DE69435067T2 (de)	2008-05-15
EP0738141A1 (en)	1996-10-23
JP2006206610A (ja)	2006-08-10
SG43833A1 (en)	1997-11-14
PT1473031E (pt)	2008-08-05
JPH09506612A (ja)	1997-06-30
HK1056116A1 (en)	2004-02-06
AU693476B2 (en)	1998-07-02
PT738141E (pt)	2008-02-11
CA2156063A1 (en)	1995-06-22
WO1995016434A1 (en)	1995-06-22
DE69435067D1 (de)	2008-03-06
AU7719294A (en)	1995-07-03
EP0738141B1 (en)	2008-01-16
JP4149511B2 (ja)	2008-09-10
DE69435106D1 (de)	2008-08-07
EP0738141A4 (en)	1998-01-07
CN1223342C (zh)	2005-10-19
CN1419911A (zh)	2003-05-28
ATE383848T1 (de)	2008-02-15
EP1473031A1 (en)	2004-11-03
CA2156063C (en)	1999-06-29
DK1473031T3 (da)	2008-10-20
ES2309441T3 (es)	2008-12-16
CN1142764A (zh)	1997-02-12

Publication	Publication Date	Title
DK0738141T3 (da)	2008-05-19	Sucroseester- og n-docosanolformuleringer
DE68921688D1 (de)	1995-04-20	Wenig reizendes Reinigungsmittel.
DE69004731D1 (de)	1994-01-05	Hilfsmittel enthaltende verdünnbare Formulierungen von Nachlaufherbiziden.
FI893579A7 (fi)	1990-01-28	Stabiloituja vetyperoksidikoostumuksia
FI951499L (fi)	1995-03-29	Kiniinihapon synteesi glukoosista
FI892676A7 (fi)	1989-12-04	Säteilynherkkiin laitteisiin liittyviä parannuksia
TR22454A (tr)	1987-07-13	Bitkilerin bueyuemesi ve verimi uezerinde etkili bilesikler ve bilesimler
FR2712590B1 (fr)	1996-03-29	Nouveaux dérivés de l'acide kojique.
LV11463A (lv)	1996-08-20	Aizvietotu 4,6-diamino-5-cianpirimidinu iegusanas panemiens
FR2596222B1 (fr)	1992-02-07	Amelioration des claviers optiques
TR26525A (tr)	1994-04-22	PIROTROID ISOMOLERININ DAHA AKTIF TüRLERE DÖNüSTüRüLMESI
DE3864509D1 (de)	1991-10-02	Alkoventrennung.
FI885708A0 (fi)	1988-12-09	Foerfarande foer metylering av xantiner.
NO874943D0 (no)	1987-11-26	Syntese av 1,1,2,2-tetrahydroperfluoralkanoler og deres estere.
FI850594A7 (fi)	1985-08-15	Perfluorialkaanikarboksyylihappojen synteesi.
FR2594373B1 (fr)	1988-12-16	Perfectionnements apportes aux marteaux anti-rebond
SU634191A1 (ru)	1978-11-25	Направленный излучатель упругих колебаний скважинного типа
KR900015583U (ko)	1990-09-01	경운기의 조작레버구조
BR9103215A (pt)	1993-02-24	Uniao de longarinas a colunas
DE3785241D1 (de)	1993-05-13	Neutralisierung von botulinus-toxin.
LV5732A4 (lv)	1996-04-20	Fenetanolamina atvasinajumi
ITMI912104A1 (it)	1993-01-29	Poliglucosidi da idrossialchilsorbitolo
IT8520750V0 (it)	1985-02-08	Struttura di pupazzo particolarmente per bambini
IT1215441B (it)	1990-02-14	Composizioni farmaceutiche adattivita' spasmolitica contenente come principio attio idanpramina
FR2586730B1 (fr)	1989-09-22	Conception d'habitations a ossature bois