ATE383853T1 - Arylessigsäuren und verwandte verbindungen zur behandlung von alzheimer-krankheit - Google Patents

Arylessigsäuren und verwandte verbindungen zur behandlung von alzheimer-krankheit

Info

Publication number
ATE383853T1
ATE383853T1 AT05758960T AT05758960T ATE383853T1 AT E383853 T1 ATE383853 T1 AT E383853T1 AT 05758960 T AT05758960 T AT 05758960T AT 05758960 T AT05758960 T AT 05758960T AT E383853 T1 ATE383853 T1 AT E383853T1
Authority
AT
Austria
Prior art keywords
treatment
arylestic
alzheimer
disease
acids
Prior art date
Application number
AT05758960T
Other languages
English (en)
Inventor
Peter Blurton
Frank Burkamp
Ian Churcher
Timothy Harrison
Joseph Neduvelil
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Application granted granted Critical
Publication of ATE383853T1 publication Critical patent/ATE383853T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
AT05758960T 2004-07-23 2005-07-19 Arylessigsäuren und verwandte verbindungen zur behandlung von alzheimer-krankheit ATE383853T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0416508.0A GB0416508D0 (en) 2004-07-23 2004-07-23 Therapeutic agents

Publications (1)

Publication Number Publication Date
ATE383853T1 true ATE383853T1 (de) 2008-02-15

Family

ID=32922716

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05758960T ATE383853T1 (de) 2004-07-23 2005-07-19 Arylessigsäuren und verwandte verbindungen zur behandlung von alzheimer-krankheit

Country Status (10)

Country Link
US (1) US20080300261A1 (de)
EP (1) EP1773315B1 (de)
JP (1) JP2008507498A (de)
CN (1) CN1993120B (de)
AT (1) ATE383853T1 (de)
AU (1) AU2005264004A1 (de)
CA (1) CA2574359A1 (de)
DE (1) DE602005004416T2 (de)
GB (1) GB0416508D0 (de)
WO (1) WO2006008558A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1650183A1 (de) * 2004-10-21 2006-04-26 Cellzome Ag (Benzyloxy-biphenyl)essigsäuren, ihre Derivate und Verwendung in der Therapie
EP1849762B1 (de) * 2006-04-21 2009-07-15 Cellzome Limited Substituierte Biphenylcarbonsäuren und deren Derivate
PL1847524T3 (pl) * 2006-04-21 2010-03-31 Cellzome Ltd Pochodne terfenylu do leczenia choroby Alzheimera
EP2121633A2 (de) 2007-02-12 2009-11-25 Merck & Co., Inc. Piperazinderivate zur behandlung von alzheimer-krankheit und verwandten leiden
US20110040094A1 (en) * 2007-09-14 2011-02-17 Envivo Pharmaceuticals, Inc. 1,3,4-trisubstituted benzenes
BRPI0817425A2 (pt) * 2007-10-19 2015-06-16 Janssen Pharmaceutica Nv Moduladores de gama-secretase ligados à amida
BRPI0817433A2 (pt) 2007-10-19 2015-06-16 Janssen Pharmaceutica Nv Moduladores de gama-secretase piperidinila e piperazinila
AU2008312355B2 (en) * 2007-10-19 2013-07-04 Janssen Pharmaceutica, N.V. Carbon linked modulators of y-secretase
EA018862B1 (ru) 2007-10-19 2013-11-29 Янссен Фармацевтика, Н.В. МОДУЛЯТОРЫ γ-СЕКРЕТАЗЫ
RU2527177C2 (ru) 2007-12-20 2014-08-27 Энвиво Фармасьютикалз, Инк. Четырехзамещенные бензолы
US7968725B2 (en) * 2008-07-22 2011-06-28 Janssen Pharmaceutica N.V. Pyridinyl modulators of γ-secretase
EP2378879A4 (de) 2008-12-16 2012-06-06 Merck Sharp & Dohme Triazolderivate für die behandlung von morbus alzheimer
WO2010138901A1 (en) * 2009-05-29 2010-12-02 Biogen Idec Ma Inc Carboxylic acid-containing compounds, derivatives thereof, and related methods of use
US8586776B2 (en) * 2009-11-05 2013-11-19 Fibrostatin, S.L. GPBP inhibition using Q2 peptidomimetics
WO2011062194A1 (ja) 2009-11-18 2011-05-26 武田薬品工業株式会社 アミノピリジン誘導体
WO2016201168A1 (en) 2015-06-10 2016-12-15 Forum Pharmceuticals Inc. Oxadiazine compounds and methods of use thereof
WO2017139414A1 (en) 2016-02-09 2017-08-17 Inventisbio Inc. Inhibitor of indoleamine-2,3-dioxygenase (ido)
WO2023146513A1 (en) * 2022-01-25 2023-08-03 Vivace Therapeutics, Inc. Compounds and methods of use thereof
DE102024115190A1 (de) * 2024-05-31 2025-12-04 Technische Universität Bergakademie Freiberg, Körperschaft des öffentlichen Rechts 2-[(3,4,5-Triphenyl)phenyl]essigsäure und Derivate sowie deren Herstellung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08325182A (ja) * 1995-05-31 1996-12-10 Fuji Yakuhin Kogyo Kk 置換テルフェニル誘導体とそれらを含有する抗血栓剤
CO4960662A1 (es) * 1997-08-28 2000-09-25 Novartis Ag Ciertos acidos 5-alquil-2-arilaminofenilaceticos y sus derivados
FR2838439B1 (fr) * 2002-04-11 2005-05-20 Sanofi Synthelabo Derives de terphenyle, leur preparation, les compositions pharmaceutqiues en contenant
GB0225548D0 (en) * 2002-11-01 2002-12-11 Glaxo Group Ltd Compounds

Also Published As

Publication number Publication date
CN1993120A (zh) 2007-07-04
WO2006008558A1 (en) 2006-01-26
US20080300261A1 (en) 2008-12-04
EP1773315A1 (de) 2007-04-18
EP1773315B1 (de) 2008-01-16
CA2574359A1 (en) 2006-01-26
GB0416508D0 (en) 2004-08-25
DE602005004416T2 (de) 2009-01-08
AU2005264004A1 (en) 2006-01-26
DE602005004416D1 (de) 2008-03-06
JP2008507498A (ja) 2008-03-13
CN1993120B (zh) 2010-05-05

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