ATE386714T1 - Verfahren zur herstellung von (1r, 2s, 4r)-(-)-2- (2'-(n,n-dimethylamino)-ethoxy) -2- phenyl -1,7, 7-tri- methyl -bicyclo[2.2.1 heptan und ihre pharmazeutisch akzeptierbaren säure-additions- salze - Google Patents

Verfahren zur herstellung von (1r, 2s, 4r)-(-)-2- (2'-(n,n-dimethylamino)-ethoxy) -2- phenyl -1,7, 7-tri- methyl -bicyclo[2.2.1 heptan und ihre pharmazeutisch akzeptierbaren säure-additions- salze

Info

Publication number: ATE386714T1
Authority: AT; Austria
Prior art keywords: bicyclo; heptane; dimethylamino; ethoxy; tri
Prior art date: 1999-05-11

Application number

AT00927613T

Other languages

English (en)

Inventor

Gyula Lukacs

Gyula Simig

Tibor Mezei

Zoltan Budai

Marta Porcs-Makkay

Gyoergy Krasznai

Kalman Nagy

Donath Gyoergyi Vereczkeyne

Tibor Szabo

Norbert Nemeth

Janos Szylagyi

Original Assignee

Egis Gyogyszergyar Nyilvanosan

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-05-11

Filing date

2000-05-10

Publication date

2008-03-15

2000-05-10 Application filed by Egis Gyogyszergyar Nyilvanosan filed Critical Egis Gyogyszergyar Nyilvanosan

2008-03-15 Application granted granted Critical

2008-03-15 Publication of ATE386714T1 publication Critical patent/ATE386714T1/de

Links

IMNFDUFMRHMDMM-UHFFFAOYSA-N N-Heptane Chemical compound CCCCCCC IMNFDUFMRHMDMM-UHFFFAOYSA-N 0.000 title 2
239000002253 acid Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
150000003839 salts Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/12—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a ring other than a six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
- C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pain & Pain Management (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT00927613T 1999-05-11 2000-05-10 Verfahren zur herstellung von (1r, 2s, 4r)-(-)-2- (2'-(n,n-dimethylamino)-ethoxy) -2- phenyl -1,7, 7-tri- methyl -bicyclo[2.2.1 heptan und ihre pharmazeutisch akzeptierbaren säure-additions- salze ATE386714T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU9901559A HU227114B1 (en)	1999-05-11	1999-05-11	(1r, 2s, 4r)-(-)-2-[n,n-(dimethylamino-ethoxy)]-2-phenyl-1,7,7-trimethyl-bicyclo[2.2.1]heptane of high purity and pharmaceutically acceptable acid addition salts thereof, process for preparation of them and medicaments containing the same

Publications (1)

Publication Number	Publication Date
ATE386714T1 true ATE386714T1 (de)	2008-03-15

Family

ID=89998272

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
AT00929730T ATE252544T1 (de)	1999-05-11	2000-05-10	Hochreine (1r, 2s, 4r)-(-)-2-((2'-(n,n- dimethylamino)-ethoxy))-2-(phenyl)-1,7,7-tri- (methyl)-bicyclo(2.2.1)heptan und ihre pharmazeutisch akzeptierbaren säure-additions- salze, verfahren zu ihrer herstellung sowie sie enthaltendes medikament.
AT00110122T ATE246170T1 (de)	1999-05-11	2000-05-10	Verfahren zur herstellung von (1r, 2s, 4r)-(-)-2- ((2'-(n,n-dimethylamino)-ethoxy))-2-(phenyl)-1, , 7-tri-(methyl)-bicyclo(2.2.1)heptan und ihre pharmazeutisch akzeptierbaren säure-additions- salze
AT00927613T ATE386714T1 (de)	1999-05-11	2000-05-10	Verfahren zur herstellung von (1r, 2s, 4r)-(-)-2- (2'-(n,n-dimethylamino)-ethoxy) -2- phenyl -1,7, 7-tri- methyl -bicyclo[2.2.1 heptan und ihre pharmazeutisch akzeptierbaren säure-additions- salze
AT00110121T ATE237579T1 (de)	1999-05-11	2000-05-10	Hochreine (1r, 2s, 4r)-(-)-2-((2'-(n,n- dimethylamino)-ethoxy))-2-(phenyl)-1,7,7-tri- (methyl)-bicyclo(2.2.1)heptan und ihre pharmazeutisch akzeptierbaren säure-additions- salze, verfahren zu ihrer herstellung sowie sie enthaltendes medikament.

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
AT00929730T ATE252544T1 (de)	1999-05-11	2000-05-10	Hochreine (1r, 2s, 4r)-(-)-2-((2'-(n,n- dimethylamino)-ethoxy))-2-(phenyl)-1,7,7-tri- (methyl)-bicyclo(2.2.1)heptan und ihre pharmazeutisch akzeptierbaren säure-additions- salze, verfahren zu ihrer herstellung sowie sie enthaltendes medikament.
AT00110122T ATE246170T1 (de)	1999-05-11	2000-05-10	Verfahren zur herstellung von (1r, 2s, 4r)-(-)-2- ((2'-(n,n-dimethylamino)-ethoxy))-2-(phenyl)-1, , 7-tri-(methyl)-bicyclo(2.2.1)heptan und ihre pharmazeutisch akzeptierbaren säure-additions- salze

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT00110121T ATE237579T1 (de)	1999-05-11	2000-05-10	Hochreine (1r, 2s, 4r)-(-)-2-((2'-(n,n- dimethylamino)-ethoxy))-2-(phenyl)-1,7,7-tri- (methyl)-bicyclo(2.2.1)heptan und ihre pharmazeutisch akzeptierbaren säure-additions- salze, verfahren zu ihrer herstellung sowie sie enthaltendes medikament.

Country Status (37)

Country	Link
US (3)	US6242386B1 (de)
EP (4)	EP1177166B1 (de)
JP (2)	JP4536265B2 (de)
KR (3)	KR20060010874A (de)
CN (2)	CN1173928C (de)
AR (2)	AR020860A1 (de)
AT (4)	ATE252544T1 (de)
AU (2)	AU776696B2 (de)
BG (2)	BG64442B1 (de)
BR (2)	BR0010412A (de)
CA (2)	CA2373193A1 (de)
CO (1)	CO5170480A1 (de)
CZ (4)	CZ290734B6 (de)
DE (4)	DE60006097T2 (de)
DK (4)	DK1177167T3 (de)
EA (2)	EA002164B1 (de)
EE (2)	EE04638B1 (de)
ES (4)	ES2302694T3 (de)
FR (2)	FR2793489B1 (de)
HR (2)	HRP20000291B1 (de)
HU (1)	HU227114B1 (de)
IL (4)	IL146420A0 (de)
IS (2)	IS6152A (de)
LT (2)	LT4928B (de)
MX (2)	MXPA01011423A (de)
MY (2)	MY122508A (de)
NO (2)	NO321486B1 (de)
NZ (2)	NZ515918A (de)
PL (2)	PL202956B1 (de)
PT (4)	PT1177167E (de)
SI (4)	SI1052245T1 (de)
SK (4)	SK6892000A3 (de)
TR (2)	TR200200147T2 (de)
TW (2)	TW528742B (de)
UA (2)	UA61122C2 (de)
WO (2)	WO2000068181A2 (de)
ZA (2)	ZA200108956B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU227114B1 (en) *	1999-05-11	2010-07-28	Egis Gyogyszergyar Nyilvanosan	(1r, 2s, 4r)-(-)-2-[n,n-(dimethylamino-ethoxy)]-2-phenyl-1,7,7-trimethyl-bicyclo[2.2.1]heptane of high purity and pharmaceutically acceptable acid addition salts thereof, process for preparation of them and medicaments containing the same
US6589996B2 (en)	2000-03-17	2003-07-08	Orion Corporation	Treatment of disorders relating to the serotonergic system
US20040082665A1 (en) *	2001-01-22	2004-04-29	Outi Maki-Ikola	Method for treating stress or tension
HUP0103017A3 (en) *	2001-07-18	2004-05-28	Egis Gyogyszergyar Nyilvanosan	Pharmaceutical composition for the treatment of diseases caused by impairment of cognitive functions and its use
GB0306604D0 (en) *	2003-03-21	2003-04-30	Curidium Ltd	Second medical use
HUP0301906A3 (en) *	2003-06-23	2006-03-28	Egis Gyogyszergyar Nyilvanosan	Use of bicyclo[2.2.1]heptane derivatives for producing of pharmaceutical compositions having neuroprotectiv activity
WO2005087213A1 (en) *	2004-03-12	2005-09-22	Egis Gyógyszergyár Nyrt.	Combination of deramciclane and opoids as analgesics
JP4916680B2 (ja) *	2005-06-30	2012-04-18	株式会社半導体エネルギー研究所	半導体装置の作製方法、剥離方法
US20080258121A1 (en) *	2007-04-23	2008-10-23	Hasan Farooq	Fire Retardant Composition
MX2012005634A (es)	2009-11-19	2012-09-07	Yissum Res Dev Co	Canfenos arilados novedosos, procesos para su preparacion y usos.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU179164B (en)	1979-12-14	1982-08-28	Egyt Gyogyszervegyeszeti Gyar	Process for producing cycloalkyl-ethers of alkanolamines
HU212574B (en) *	1990-09-21	1996-08-29	Egyt Gyogyszervegyeszeti Gyar	Process for producing (1r,2s)-(-)-2-phenyl-(2'-dimethyl-amino-etoxy)-1,7,7-trimethyl-bicyclo[2.2.1.]heptane
HU214588B (hu) *	1994-07-01	1998-04-28	EGIS Gyógyszergyár Rt.	Eljárás bicikloheptán-származékot tartalmazó, CCK-rendszer gátló hatású gyógyászati készítmények előállítására
HU226061B1 (en)	1996-10-17	2008-04-28	Egis Gyogyszergyar Nyilvanosan	1,7,7-trimethyl-bicyclo[2.2.1]heptane derivative, pharmaceutical compositions containing the same and process for their preparation
HUP9900445A2 (hu)	1999-02-24	2001-06-28	EGIS Gyógyszergyár Rt.	Eljárás (1R,2S,4R)-(-)-N,N-(dimetilamino-etoxi)-2-fenil-1,7,7-trimetil-biciklo[2.2.1]heptán előállítására és ennek köztiterméke
HU227114B1 (en) *	1999-05-11	2010-07-28	Egis Gyogyszergyar Nyilvanosan	(1r, 2s, 4r)-(-)-2-[n,n-(dimethylamino-ethoxy)]-2-phenyl-1,7,7-trimethyl-bicyclo[2.2.1]heptane of high purity and pharmaceutically acceptable acid addition salts thereof, process for preparation of them and medicaments containing the same

1999
- 1999-05-11 HU HU9901559A patent/HU227114B1/hu not_active IP Right Cessation
2000
- 2000-05-10 CZ CZ20001722A patent/CZ290734B6/cs not_active IP Right Cessation
- 2000-05-10 SI SI200030124T patent/SI1052245T1/xx unknown
- 2000-05-10 KR KR1020067001294A patent/KR20060010874A/ko not_active Ceased
- 2000-05-10 DK DK00929730T patent/DK1177167T3/da active
- 2000-05-10 MX MXPA01011423A patent/MXPA01011423A/es active IP Right Grant
- 2000-05-10 BR BR0010412-4A patent/BR0010412A/pt not_active Application Discontinuation
- 2000-05-10 PT PT00929730T patent/PT1177167E/pt unknown
- 2000-05-10 EP EP00927613A patent/EP1177166B1/de not_active Expired - Lifetime
- 2000-05-10 ES ES00927613T patent/ES2302694T3/es not_active Expired - Lifetime
- 2000-05-10 JP JP2000617164A patent/JP4536265B2/ja not_active Expired - Fee Related
- 2000-05-10 SI SI200030989T patent/SI1177166T1/sl unknown
- 2000-05-10 ES ES00929730T patent/ES2208328T3/es not_active Expired - Lifetime
- 2000-05-10 MY MYPI20002033A patent/MY122508A/en unknown
- 2000-05-10 CO CO00033730A patent/CO5170480A1/es not_active Application Discontinuation
- 2000-05-10 UA UA2000052642A patent/UA61122C2/uk unknown
- 2000-05-10 EP EP00929730A patent/EP1177167B1/de not_active Expired - Lifetime
- 2000-05-10 HR HR20000291A patent/HRP20000291B1/xx not_active IP Right Cessation
- 2000-05-10 TR TR2002/00147T patent/TR200200147T2/xx unknown
- 2000-05-10 EP EP00110122A patent/EP1052243B1/de not_active Expired - Lifetime
- 2000-05-10 AT AT00929730T patent/ATE252544T1/de not_active IP Right Cessation
- 2000-05-10 IL IL14642000A patent/IL146420A0/xx active IP Right Grant
- 2000-05-10 FR FR0005940A patent/FR2793489B1/fr not_active Expired - Fee Related
- 2000-05-10 CZ CZ20001723A patent/CZ291329B6/cs not_active IP Right Cessation
- 2000-05-10 PL PL340108A patent/PL202956B1/pl not_active IP Right Cessation
- 2000-05-10 DK DK00927613T patent/DK1177166T3/da active
- 2000-05-10 IL IL14642100A patent/IL146421A0/xx active IP Right Grant
- 2000-05-10 SI SI200030292T patent/SI1177167T1/xx unknown
- 2000-05-10 PT PT00110121T patent/PT1052245E/pt unknown
- 2000-05-10 NZ NZ515918A patent/NZ515918A/xx not_active IP Right Cessation
- 2000-05-10 SK SK689-2000A patent/SK6892000A3/sk unknown
- 2000-05-10 NZ NZ515917A patent/NZ515917A/xx unknown
- 2000-05-10 EA EA200000411A patent/EA002164B1/ru not_active IP Right Cessation
- 2000-05-10 SK SK1624-2001A patent/SK285780B6/sk not_active IP Right Cessation
- 2000-05-10 JP JP2000617162A patent/JP4031203B2/ja not_active Expired - Fee Related
- 2000-05-10 TW TW089108902A patent/TW528742B/zh not_active IP Right Cessation
- 2000-05-10 MY MYPI20002032A patent/MY123523A/en unknown
- 2000-05-10 CZ CZ20014050A patent/CZ20014050A3/cs unknown
- 2000-05-10 DK DK00110121T patent/DK1052245T3/da active
- 2000-05-10 AT AT00110122T patent/ATE246170T1/de not_active IP Right Cessation
- 2000-05-10 SI SI200030219T patent/SI1052243T1/xx unknown
- 2000-05-10 DE DE60006097T patent/DE60006097T2/de not_active Expired - Lifetime
- 2000-05-10 UA UA2000052641A patent/UA49974C2/uk unknown
- 2000-05-10 ES ES00110122T patent/ES2203373T3/es not_active Expired - Lifetime
- 2000-05-10 DK DK00110122T patent/DK1052243T3/da active
- 2000-05-10 BR BR0010406-0A patent/BR0010406A/pt not_active Application Discontinuation
- 2000-05-10 US US09/569,050 patent/US6242386B1/en not_active Expired - Fee Related
- 2000-05-10 BG BG104416A patent/BG64442B1/bg unknown
- 2000-05-10 AU AU46003/00A patent/AU776696B2/en not_active Ceased
- 2000-05-10 EE EEP200100595A patent/EE04638B1/xx not_active IP Right Cessation
- 2000-05-10 MX MXPA01011420A patent/MXPA01011420A/es active IP Right Grant
- 2000-05-10 EE EEP200100596A patent/EE200100596A/xx not_active IP Right Cessation
- 2000-05-10 CA CA002373193A patent/CA2373193A1/en not_active Abandoned
- 2000-05-10 AU AU47731/00A patent/AU777737B2/en not_active Ceased
- 2000-05-10 SK SK1623-2001A patent/SK285635B6/sk not_active IP Right Cessation
- 2000-05-10 FR FR0005941A patent/FR2793490B1/fr not_active Expired - Fee Related
- 2000-05-10 EA EA200000410A patent/EA002163B1/ru not_active IP Right Cessation
- 2000-05-10 CZ CZ20014051A patent/CZ20014051A3/cs unknown
- 2000-05-10 CN CNB008082391A patent/CN1173928C/zh not_active Expired - Fee Related
- 2000-05-10 HR HR20000290A patent/HRP20000290B1/xx not_active IP Right Cessation
- 2000-05-10 DE DE60038112T patent/DE60038112T8/de not_active Expired - Fee Related
- 2000-05-10 SK SK690-2000A patent/SK6902000A3/sk unknown
- 2000-05-10 WO PCT/HU2000/000043 patent/WO2000068181A2/en not_active Ceased
- 2000-05-10 AT AT00927613T patent/ATE386714T1/de not_active IP Right Cessation
- 2000-05-10 DE DE60002117T patent/DE60002117T2/de not_active Expired - Lifetime
- 2000-05-10 AR ARP000102244A patent/AR020860A1/es not_active Application Discontinuation
- 2000-05-10 US US09/569,046 patent/US6335469B1/en not_active Expired - Lifetime
- 2000-05-10 AT AT00110121T patent/ATE237579T1/de not_active IP Right Cessation
- 2000-05-10 CN CNB008083576A patent/CN1325465C/zh not_active Expired - Fee Related
- 2000-05-10 AR ARP000102239A patent/AR023900A1/es active IP Right Grant
- 2000-05-10 ES ES00110121T patent/ES2194643T3/es not_active Expired - Lifetime
- 2000-05-10 DE DE60004126T patent/DE60004126T2/de not_active Expired - Fee Related
- 2000-05-10 WO PCT/HU2000/000044 patent/WO2000068183A2/en not_active Ceased
- 2000-05-10 TR TR2002/00148T patent/TR200200148T2/xx unknown
- 2000-05-10 PL PL00340107A patent/PL340107A1/xx not_active IP Right Cessation
- 2000-05-10 PT PT00927613T patent/PT1177166E/pt unknown
- 2000-05-10 KR KR1020017014354A patent/KR100685071B1/ko not_active Expired - Fee Related
- 2000-05-10 PT PT00110122T patent/PT1052243E/pt unknown
- 2000-05-10 TW TW089108901A patent/TWI286541B/zh not_active IP Right Cessation
- 2000-05-10 KR KR1020017014355A patent/KR100581489B1/ko not_active Expired - Fee Related
- 2000-05-10 CA CA2369393A patent/CA2369393C/en not_active Expired - Fee Related
- 2000-05-10 EP EP00110121A patent/EP1052245B1/de not_active Expired - Lifetime
- 2000-05-10 BG BG104417A patent/BG64673B1/bg unknown
2001
- 2001-10-30 ZA ZA200108956A patent/ZA200108956B/en unknown
- 2001-10-30 ZA ZA200108958A patent/ZA200108958B/en unknown
- 2001-10-30 US US09/984,542 patent/US6624201B2/en not_active Expired - Lifetime
- 2001-10-31 NO NO20015336A patent/NO321486B1/no not_active IP Right Cessation
- 2001-11-01 NO NO20015352A patent/NO321487B1/no unknown
- 2001-11-08 LT LT2001108A patent/LT4928B/lt not_active IP Right Cessation
- 2001-11-08 LT LT2001109A patent/LT4927B/lt not_active IP Right Cessation
- 2001-11-09 IS IS6152A patent/IS6152A/is unknown
- 2001-11-09 IS IS6153A patent/IS2570B/is unknown
- 2001-11-11 IL IL146421A patent/IL146421A/en not_active IP Right Cessation
- 2001-11-11 IL IL146420A patent/IL146420A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
EE04672B1 (de)	2006-08-15
DE60038112T2 (de)	2009-02-12
JP4031203B2 (ja)	2008-01-09
LT2001109A (en)	2002-03-25
SI1052245T1 (en)	2003-10-31
EP1177166B1 (de)	2008-02-20
DK1052245T3 (da)	2003-08-11
FR2793490A1 (fr)	2000-11-17
SK16232001A3 (sk)	2002-04-04
PT1177166E (pt)	2008-06-02
FR2793489A1 (fr)	2000-11-17
KR100685071B1 (ko)	2007-02-22
ZA200108956B (en)	2003-02-17
CN1353686A (zh)	2002-06-12
FR2793489B1 (fr)	2004-04-02
US6242386B1 (en)	2001-06-05
SI1177166T1 (sl)	2008-08-31
MXPA01011423A (es)	2002-06-04
JP2002544185A (ja)	2002-12-24
MXPA01011420A (es)	2002-06-04
LT4928B (lt)	2002-07-25
WO2000068183A3 (en)	2001-07-26
MY123523A (en)	2006-05-31
HRP20000290A2 (en)	2005-02-28
DE60004126T2 (de)	2004-04-22
CN1173928C (zh)	2004-11-03
BG104417A (en)	2001-03-30
BR0010406A (pt)	2002-02-13
EP1052243A2 (de)	2000-11-15
HRP20000290B1 (en)	2007-08-31
CZ20014050A3 (cs)	2002-05-15
UA49974C2 (uk)	2002-10-15
CA2373193A1 (en)	2000-11-16
KR20020010914A (ko)	2002-02-06
PL340108A1 (en)	2000-11-20
EP1052245A3 (de)	2001-02-28
MY122508A (en)	2006-04-29
DE60002117T2 (de)	2003-12-24
IL146421A0 (en)	2002-07-25
BG104416A (en)	2001-03-30
DE60006097D1 (de)	2003-11-27
NO20015352L (no)	2002-01-08
CZ20001722A3 (cs)	2000-12-13
TWI286541B (en)	2007-09-11
CA2369393A1 (en)	2000-11-16
ATE237579T1 (de)	2003-05-15
HU227114B1 (en)	2010-07-28
AU777737B2 (en)	2004-10-28
IL146420A (en)	2007-06-03
DE60006097T2 (de)	2004-06-17
BR0010412A (pt)	2002-02-13
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HUP9901559A2 (hu)	2002-01-28
DK1177167T3 (da)	2004-03-01
PT1052243E (pt)	2003-12-31
LT2001108A (en)	2002-03-25
EA200000410A3 (ru)	2001-02-26
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SK285635B6 (sk)	2007-05-03
AR020860A1 (es)	2002-05-29
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SK6892000A3 (en)	2000-12-11
AU4773100A (en)	2000-11-21
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ES2208328T3 (es)	2004-06-16
IL146421A (en)	2008-11-26
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