ES2194643T3 - (1r,2s,4r)-(-)-2-((2'-(n,n-dimetilamino)-etoxi))-2-(fenil)-1,7,7-tri(metil)-biciclo(2,2,1)heptano de elevada pureza, sus sales de adicion farmaceuticamente aceptables, su procedimiento de preparacion y los medicamentos que los contienen. - Google Patents

(1r,2s,4r)-(-)-2-((2'-(n,n-dimetilamino)-etoxi))-2-(fenil)-1,7,7-tri(metil)-biciclo(2,2,1)heptano de elevada pureza, sus sales de adicion farmaceuticamente aceptables, su procedimiento de preparacion y los medicamentos que los contienen.

Info

Publication number
ES2194643T3
ES2194643T3 ES00110121T ES00110121T ES2194643T3 ES 2194643 T3 ES2194643 T3 ES 2194643T3 ES 00110121 T ES00110121 T ES 00110121T ES 00110121 T ES00110121 T ES 00110121T ES 2194643 T3 ES2194643 T3 ES 2194643T3
Authority
ES
Spain
Prior art keywords
tri
phenyl
methyl
pharmaceutically acceptable
addition salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES00110121T
Other languages
English (en)
Inventor
Gyula Lukacs
Gyula Simig
Tibor Mezei
Zoltan Budai
Marta Porcs-Makkay
Gyorgy Krasznai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Egis Gyógyszergyár Zrt
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Egis Gyógyszergyár Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Gyógyszergyár Zrt filed Critical Egyt Gyogyszervegyeszeti Gyar
Application granted granted Critical
Publication of ES2194643T3 publication Critical patent/ES2194643T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/12—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

(1R, 2S, 4R)-(-)-2-[(2¿-{N, N-dimetilamino}-etoxi)]-2-[fenil]-1, 7, 7-tri-[metil]-biciclo[2.2.1]heptano de fórmula **FORMULA** y sales de adición de ácido farmacéuticamente aceptables del mismo, caracterizados porque contienen
ES00110121T 1999-05-11 2000-05-10 (1r,2s,4r)-(-)-2-((2'-(n,n-dimetilamino)-etoxi))-2-(fenil)-1,7,7-tri(metil)-biciclo(2,2,1)heptano de elevada pureza, sus sales de adicion farmaceuticamente aceptables, su procedimiento de preparacion y los medicamentos que los contienen. Expired - Lifetime ES2194643T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9901559A HU227114B1 (en) 1999-05-11 1999-05-11 (1r, 2s, 4r)-(-)-2-[n,n-(dimethylamino-ethoxy)]-2-phenyl-1,7,7-trimethyl-bicyclo[2.2.1]heptane of high purity and pharmaceutically acceptable acid addition salts thereof, process for preparation of them and medicaments containing the same

Publications (1)

Publication Number Publication Date
ES2194643T3 true ES2194643T3 (es) 2003-12-01

Family

ID=89998272

Family Applications (4)

Application Number Title Priority Date Filing Date
ES00110121T Expired - Lifetime ES2194643T3 (es) 1999-05-11 2000-05-10 (1r,2s,4r)-(-)-2-((2'-(n,n-dimetilamino)-etoxi))-2-(fenil)-1,7,7-tri(metil)-biciclo(2,2,1)heptano de elevada pureza, sus sales de adicion farmaceuticamente aceptables, su procedimiento de preparacion y los medicamentos que los contienen.
ES00927613T Expired - Lifetime ES2302694T3 (es) 1999-05-11 2000-05-10 Procedimiento para la preparacion de (1r,2s,4r)-(-)-2-(2'-n,n-dimetilamino-etoxi)-2-fenil-1,7,7-tri-metil-biciclo 2.2.1 heptano y sus sales de adicion de acido farmaceuticamente aceptables.
ES00110122T Expired - Lifetime ES2203373T3 (es) 1999-05-11 2000-05-10 Procedimiento para preparar (1r,2s,4r)-(-)-2-((2'-(n,n-dimetilamino)-etoxi))-2-(fenil)-1,7,7-tri-(metil)-biciclo(2.2.1)heptano y las sales de adicion de acido farmaceuticamente aceptables del mismo.
ES00929730T Expired - Lifetime ES2208328T3 (es) 1999-05-11 2000-05-10 "(r,2s,3r)-(-)-2-((2`-)n,n-dimetilamino)-2-(fenil)-1,7,7-tri-(mentil)-biciclo(2.2.1)heptano de gran pureza, sus sales de adicion acida farmaceutica aceptables y procedimiento para la preparacion de estos compuestos asi como medicamentos que los contienen.

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES00927613T Expired - Lifetime ES2302694T3 (es) 1999-05-11 2000-05-10 Procedimiento para la preparacion de (1r,2s,4r)-(-)-2-(2'-n,n-dimetilamino-etoxi)-2-fenil-1,7,7-tri-metil-biciclo 2.2.1 heptano y sus sales de adicion de acido farmaceuticamente aceptables.
ES00110122T Expired - Lifetime ES2203373T3 (es) 1999-05-11 2000-05-10 Procedimiento para preparar (1r,2s,4r)-(-)-2-((2'-(n,n-dimetilamino)-etoxi))-2-(fenil)-1,7,7-tri-(metil)-biciclo(2.2.1)heptano y las sales de adicion de acido farmaceuticamente aceptables del mismo.
ES00929730T Expired - Lifetime ES2208328T3 (es) 1999-05-11 2000-05-10 "(r,2s,3r)-(-)-2-((2`-)n,n-dimetilamino)-2-(fenil)-1,7,7-tri-(mentil)-biciclo(2.2.1)heptano de gran pureza, sus sales de adicion acida farmaceutica aceptables y procedimiento para la preparacion de estos compuestos asi como medicamentos que los contienen.

Country Status (37)

Country Link
US (3) US6242386B1 (es)
EP (4) EP1177166B1 (es)
JP (2) JP4536265B2 (es)
KR (3) KR100685071B1 (es)
CN (2) CN1173928C (es)
AR (2) AR023900A1 (es)
AT (4) ATE237579T1 (es)
AU (2) AU777737B2 (es)
BG (2) BG64673B1 (es)
BR (2) BR0010412A (es)
CA (2) CA2369393C (es)
CO (1) CO5170480A1 (es)
CZ (4) CZ291329B6 (es)
DE (4) DE60038112T8 (es)
DK (4) DK1052243T3 (es)
EA (2) EA002164B1 (es)
EE (2) EE04638B1 (es)
ES (4) ES2194643T3 (es)
FR (2) FR2793490B1 (es)
HR (2) HRP20000290B1 (es)
HU (1) HU227114B1 (es)
IL (4) IL146420A0 (es)
IS (2) IS6152A (es)
LT (2) LT4927B (es)
MX (2) MXPA01011423A (es)
MY (2) MY123523A (es)
NO (2) NO321486B1 (es)
NZ (2) NZ515918A (es)
PL (2) PL202956B1 (es)
PT (4) PT1177167E (es)
SI (4) SI1052245T1 (es)
SK (4) SK6892000A3 (es)
TR (2) TR200200147T2 (es)
TW (2) TWI286541B (es)
UA (2) UA49974C2 (es)
WO (2) WO2000068183A2 (es)
ZA (2) ZA200108958B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU227114B1 (en) * 1999-05-11 2010-07-28 Egis Gyogyszergyar Nyilvanosan (1r, 2s, 4r)-(-)-2-[n,n-(dimethylamino-ethoxy)]-2-phenyl-1,7,7-trimethyl-bicyclo[2.2.1]heptane of high purity and pharmaceutically acceptable acid addition salts thereof, process for preparation of them and medicaments containing the same
US6589996B2 (en) 2000-03-17 2003-07-08 Orion Corporation Treatment of disorders relating to the serotonergic system
US20040082665A1 (en) * 2001-01-22 2004-04-29 Outi Maki-Ikola Method for treating stress or tension
HUP0103017A3 (en) * 2001-07-18 2004-05-28 Egis Gyogyszergyar Nyilvanosan Pharmaceutical composition for the treatment of diseases caused by impairment of cognitive functions and its use
GB0306604D0 (en) * 2003-03-21 2003-04-30 Curidium Ltd Second medical use
HUP0301906A3 (en) * 2003-06-23 2006-03-28 Egis Gyogyszergyar Nyilvanosan Use of bicyclo[2.2.1]heptane derivatives for producing of pharmaceutical compositions having neuroprotectiv activity
EA010691B1 (ru) * 2004-03-12 2008-10-30 Эгиш Дьёдьсердьяр Нирт. Комбинация дерамциклана и опиоидов в качестве обезболивающего средства
JP4916680B2 (ja) * 2005-06-30 2012-04-18 株式会社半導体エネルギー研究所 半導体装置の作製方法、剥離方法
US20080258121A1 (en) * 2007-04-23 2008-10-23 Hasan Farooq Fire Retardant Composition
RU2578715C2 (ru) 2009-11-19 2016-03-27 Йиссум Рисерч Дивелопмент Компани Оф Дзе Хебрю Юниверсити Оф Иерусалим, Лтд. Новые арилированные камфены, способы их получения и их применения

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU179164B (en) * 1979-12-14 1982-08-28 Egyt Gyogyszervegyeszeti Gyar Process for producing cycloalkyl-ethers of alkanolamines
HU212574B (en) * 1990-09-21 1996-08-29 Egyt Gyogyszervegyeszeti Gyar Process for producing (1r,2s)-(-)-2-phenyl-(2'-dimethyl-amino-etoxy)-1,7,7-trimethyl-bicyclo[2.2.1.]heptane
HU214588B (hu) * 1994-07-01 1998-04-28 EGIS Gyógyszergyár Rt. Eljárás bicikloheptán-származékot tartalmazó, CCK-rendszer gátló hatású gyógyászati készítmények előállítására
HU226061B1 (en) 1996-10-17 2008-04-28 Egis Gyogyszergyar Nyilvanosan 1,7,7-trimethyl-bicyclo[2.2.1]heptane derivative, pharmaceutical compositions containing the same and process for their preparation
HUP9900445A2 (hu) 1999-02-24 2001-06-28 EGIS Gyógyszergyár Rt. Eljárás (1R,2S,4R)-(-)-N,N-(dimetilamino-etoxi)-2-fenil-1,7,7-trimetil-biciklo[2.2.1]heptán előállítására és ennek köztiterméke
HU227114B1 (en) * 1999-05-11 2010-07-28 Egis Gyogyszergyar Nyilvanosan (1r, 2s, 4r)-(-)-2-[n,n-(dimethylamino-ethoxy)]-2-phenyl-1,7,7-trimethyl-bicyclo[2.2.1]heptane of high purity and pharmaceutically acceptable acid addition salts thereof, process for preparation of them and medicaments containing the same

Also Published As

Publication number Publication date
LT2001109A (en) 2002-03-25
ES2208328T3 (es) 2004-06-16
EP1052243A2 (en) 2000-11-15
DE60006097T2 (de) 2004-06-17
DK1177167T3 (da) 2004-03-01
US20020040164A1 (en) 2002-04-04
JP4536265B2 (ja) 2010-09-01
KR20020010914A (ko) 2002-02-06
PL340108A1 (en) 2000-11-20
SK285780B6 (sk) 2007-08-02
UA49974C2 (uk) 2002-10-15
CA2369393A1 (en) 2000-11-16
AU777737B2 (en) 2004-10-28
EE200100596A (et) 2003-02-17
FR2793490A1 (fr) 2000-11-17
NO20015336L (no) 2002-01-08
ZA200108956B (en) 2003-02-17
SK16232001A3 (sk) 2002-04-04
HU9901559D0 (en) 1999-07-28
EP1177167B1 (en) 2003-10-22
SI1177166T1 (sl) 2008-08-31
US6242386B1 (en) 2001-06-05
HRP20000290A2 (en) 2005-02-28
TR200200147T2 (tr) 2002-06-21
ES2203373T3 (es) 2004-04-16
HK1031372A1 (en) 2001-06-15
ZA200108958B (en) 2002-10-30
EE04638B1 (et) 2006-06-15
PL202956B1 (pl) 2009-08-31
PT1177167E (pt) 2004-03-31
DE60002117T2 (de) 2003-12-24
NO321487B1 (no) 2006-05-15
EA200000411A3 (ru) 2001-02-26
IS2570B (is) 2010-01-15
FR2793489B1 (fr) 2004-04-02
CA2373193A1 (en) 2000-11-16
EA200000410A2 (ru) 2000-12-25
DK1052245T3 (da) 2003-08-11
EP1052245A3 (en) 2001-02-28
DE60038112D1 (de) 2008-04-03
TR200200148T2 (tr) 2002-06-21
HK1031220A1 (en) 2001-06-08
HRP20000291B1 (en) 2005-06-30
HRP20000291A2 (en) 2001-06-30
EP1052245A2 (en) 2000-11-15
KR100685071B1 (ko) 2007-02-22
EE04672B1 (es) 2006-08-15
AU776696B2 (en) 2004-09-16
BG64442B1 (en) 2005-02-28
DE60002117D1 (de) 2003-05-22
MY122508A (en) 2006-04-29
KR100581489B1 (ko) 2006-05-22
SK6892000A3 (en) 2000-12-11
AR020860A1 (es) 2002-05-29
CZ290734B6 (cs) 2002-10-16
BR0010412A (pt) 2002-02-13
PT1052243E (pt) 2003-12-31
IL146420A0 (en) 2002-07-25
CN1325465C (zh) 2007-07-11
CZ20001723A3 (cs) 2000-12-13
DE60038112T8 (de) 2009-05-28
MXPA01011423A (es) 2002-06-04
TWI286541B (en) 2007-09-11
EP1052243A3 (en) 2001-02-28
DE60006097D1 (de) 2003-11-27
EA002164B1 (ru) 2001-12-24
IS6153A (is) 2001-11-09
SI1052245T1 (en) 2003-10-31
CO5170480A1 (es) 2002-06-27
NO20015352L (no) 2002-01-08
EA002163B1 (ru) 2001-12-24
HU227114B1 (en) 2010-07-28
IS6152A (is) 2001-11-09
UA61122C2 (uk) 2003-11-17
SK6902000A3 (en) 2000-12-11
JP4031203B2 (ja) 2008-01-09
JP2002544184A (ja) 2002-12-24
US6624201B2 (en) 2003-09-23
WO2000068183A3 (en) 2001-07-26
NO20015352D0 (no) 2001-11-01
SI1052243T1 (en) 2004-02-29
AU4600300A (en) 2000-11-21
CN1353687A (zh) 2002-06-12
EP1177166B1 (en) 2008-02-20
CA2369393C (en) 2010-07-06
LT2001108A (en) 2002-03-25
ATE246170T1 (de) 2003-08-15
EA200000411A2 (ru) 2000-12-25
PT1177166E (pt) 2008-06-02
ATE252544T1 (de) 2003-11-15
NZ515917A (en) 2004-02-27
BG104417A (en) 2001-03-30
WO2000068183A2 (en) 2000-11-16
MXPA01011420A (es) 2002-06-04
HRP20000290B1 (en) 2007-08-31
ATE386714T1 (de) 2008-03-15
IL146421A0 (en) 2002-07-25
DE60004126D1 (de) 2003-09-04
WO2000068181A3 (en) 2001-06-28
LT4927B (lt) 2002-07-25
EP1177167A2 (en) 2002-02-06
PT1052245E (pt) 2003-09-30
NO20015336D0 (no) 2001-10-31
DE60004126T2 (de) 2004-04-22
ATE237579T1 (de) 2003-05-15
KR20060010874A (ko) 2006-02-02
DK1177166T3 (da) 2008-06-16
CN1173928C (zh) 2004-11-03
CZ20014051A3 (cs) 2002-05-15
DK1052243T3 (da) 2003-11-24
US6335469B1 (en) 2002-01-01
BG104416A (en) 2001-03-30
IL146420A (en) 2007-06-03
DE60038112T2 (de) 2009-02-12
ES2302694T3 (es) 2008-08-01
FR2793489A1 (fr) 2000-11-17
NZ515918A (en) 2004-02-27
BG64673B1 (bg) 2005-11-30
BR0010406A (pt) 2002-02-13
PL340107A1 (en) 2000-11-20
SK285635B6 (sk) 2007-05-03
KR20010112486A (ko) 2001-12-20
FR2793490B1 (fr) 2004-04-23
NO321486B1 (no) 2006-05-15
EP1052245B1 (en) 2003-04-16
EP1177166A2 (en) 2002-02-06
HUP9901559A2 (hu) 2002-01-28
EP1052243B1 (en) 2003-07-30
TW528742B (en) 2003-04-21
AU4773100A (en) 2000-11-21
CZ20014050A3 (cs) 2002-05-15
CZ291329B6 (cs) 2003-02-12
LT4928B (lt) 2002-07-25
EE200100595A (et) 2003-02-17
IL146421A (en) 2008-11-26
MY123523A (en) 2006-05-31
CN1353686A (zh) 2002-06-12
AR023900A1 (es) 2002-09-04
CZ20001722A3 (cs) 2000-12-13
WO2000068181A2 (en) 2000-11-16
JP2002544185A (ja) 2002-12-24
SK16242001A3 (sk) 2002-04-04
EA200000410A3 (ru) 2001-02-26
SI1177167T1 (en) 2004-04-30

Similar Documents

Publication Publication Date Title
SE8804629D0 (sv) New therapeutically active compounds
GEP20053454B (en) Aryl Fused Azapolycyclic Compounds, Composition Containing the Same and Use Thereof
DE60144304D1 (de) Stabile pharmazeutische Lösungsformulierungen für unter Druck stehende Inhaliergeräte für die Verabreichung abgemessener Dosen
SE9904505D0 (sv) Novel compounds
BR0015605A (pt) Composição e uso
BR9912694A (pt) Composto para preparar medicamento de administração pulmonar
BR0015567A (pt) Compostos de ácido fenoxicarboxìlico e composições para liberar agentes ativos
SV2004001418A (es) Formulaciones farmaceuticas de 5,7,14-triazaciclo 10.3.1.0.2,11.04,9) -hexadeca-2(11),3,5,7,9-pentaeno" ref.pc 23248
AR057753A2 (es) Derivados de quinazolina, proceso para su preparacion y composiciones farmaceuticas que los contienen
CY1108532T1 (el) Ενωσεις και συνθεσεις για την παροχη δραστικων παραγοντων
AR004700A1 (es) 1alfa, 26 dihidroxi-d-homo-vitamina d3, una composicion farmaceutica que la comprende, un procedimiento para su preparacion y el uso de los mismos en laelaboracion de un medicamento
HU229443B1 (en) Betha-carboline particulate form, pharmaceutical compositions containing it, their preparations and their use
SE0102440D0 (sv) New compound
CO4940448A1 (es) Modificacion a cristal de una sustancia de medicamento
LV10267A (lv) Savienojums arstniecibas lidzeklis panemiens savienojuma iegusanai
EE200100596A (et) Ülipuhas (1R,2S,4R)-(-)-2-[(2'-{N,N-dimetüülamino}etoksü)]-2-[fenüül]-1,7,7-tri[metüül]bitsüklo[2.2.1 ]heptaan ja selle farmatseutiliselt vastuvõetavad happeliitsoolad ning nimetatud ühendite, samutiravimite, mis sisaldavad üks või enam nimetatud üh
UY26459A1 (es) 3,4-dihidroquinazolinas 5,6-disustituidas
ECSP003551A (es) Complejo farmaceutico
EP1245562A4 (en) ALCOHOLS 5-THIA- "OMEGA" - (PHENYL SUBSTITUTED) - PROSTAGLANDIN E, PROCESS FOR THE PREPARATION OF SUCH ALCOHOLS AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE ALCOHOLS AS ACTIVE INGREDIENT.
AR008536A1 (es) Utilizacion de la tienilciclohexilamina bajo forma racemica, de diastereoisomeros o de enantiomeros sustancialmente puros, sola o en asociacioncon otras sustancias de actividad farmaceutica para preparar un medicamento destinado a limitar o inhibir los efectos debidos a productos neurotoxicos o neur
IL152751A0 (en) Optically active 2-aminotetralin derivatives, the processes for the preparation thereof and the therapeutical use of pharmaceutical compositions containing them
FR2818908B1 (fr) Utilisation en tant que medicament d'un compose restituant in vivo des principes actifs
ECSP045014A (es) Compuestos novedosos
CO5170481A1 (es) Procedimiento para la preparacion de (1r,2s,4r)-(-)-2-[(2`-(n,n-dimetilamino) - etoxi)]-2-[fenil]-1,7,7-tri-[metil]-biciclo[2.2.1] heptano (deramciclano) de alta pureza y sus sales farmaceuticamente aceptables
ES2057542T3 (es) Agentes terapeuticos.