ATE386745T1 - Verfahren für die synthese von perindopril und seiner pharmazeutisch annehmbaren salzen - Google Patents

Verfahren für die synthese von perindopril und seiner pharmazeutisch annehmbaren salzen

Info

Publication number: ATE386745T1
Authority: AT; Austria
Prior art keywords: perindopril; synthesis; pharmaceutically acceptable; acceptable salts; salts
Prior art date: 2003-12-10

Application number

AT03293084T

Other languages

English (en)

Inventor

Thierry Dubuffet

Jean-Pierre Lecouve

Original Assignee

Servier Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-12-10

Filing date

2003-12-10

Publication date

2008-03-15

2003-12-10 Application filed by Servier Lab filed Critical Servier Lab

2008-03-15 Application granted granted Critical

2008-03-15 Publication of ATE386745T1 publication Critical patent/ATE386745T1/de

Links

230000015572 biosynthetic process Effects 0.000 title 1
238000000034 method Methods 0.000 title 1
IPVQLZZIHOAWMC-QXKUPLGCSA-N perindopril Chemical compound C1CCC[C@H]2C[C@@H](C(O)=O)N(C(=O)[C@H](C)N[C@@H](CCC)C(=O)OCC)[C@H]21 IPVQLZZIHOAWMC-QXKUPLGCSA-N 0.000 title 1
229960002582 perindopril Drugs 0.000 title 1
150000003839 salts Chemical class 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Peptides Or Proteins (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT03293084T 2003-12-10 2003-12-10 Verfahren für die synthese von perindopril und seiner pharmazeutisch annehmbaren salzen ATE386745T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP03293084A EP1420029B9 (de)	2003-12-10	2003-12-10	Verfahren für die Synthese von Perindopril und seiner pharmazeutisch annehmbaren Salzen

Publications (1)

Publication Number	Publication Date
ATE386745T1 true ATE386745T1 (de)	2008-03-15

Family

ID=32116381

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03293084T ATE386745T1 (de)	2003-12-10	2003-12-10	Verfahren für die synthese von perindopril und seiner pharmazeutisch annehmbaren salzen

Country Status (26)

Country	Link
US (1)	US7279583B2 (de)
EP (1)	EP1420029B9 (de)
JP (1)	JP4377413B2 (de)
KR (1)	KR100825537B1 (de)
CN (1)	CN100453552C (de)
AR (1)	AR047327A1 (de)
AT (1)	ATE386745T1 (de)
AU (1)	AU2004312185B2 (de)
BR (1)	BRPI0417423B1 (de)
CA (1)	CA2548405C (de)
CY (1)	CY1108238T1 (de)
DE (1)	DE60319196T2 (de)
DK (1)	DK1420029T3 (de)
EA (1)	EA012034B1 (de)
ES (1)	ES2300555T3 (de)
GE (1)	GEP20084370B (de)
MA (1)	MA28222A1 (de)
MY (1)	MY139289A (de)
NO (1)	NO20063012L (de)
NZ (1)	NZ547550A (de)
PL (1)	PL211485B1 (de)
PT (1)	PT1420029E (de)
SI (1)	SI1420029T1 (de)
UA (1)	UA84898C2 (de)
WO (1)	WO2005066198A1 (de)
ZA (1)	ZA200604369B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2413128A (en) *	2004-04-13	2005-10-19	Neopharma Ltd	Process for the preparation of perindopril
EP1987828A1 (de) *	2005-01-06	2008-11-05	IPCA Laboratories Limited	perindopril-salzen und ihre verwendung bei der behandlung von hypertonie
WO2006131828A1 (en) *	2005-06-08	2006-12-14	Aurobindo Pharma Limited	A process for the preparation of perindopril
DK2318365T3 (en)	2008-06-24	2015-11-23	Mylan Lab Ltd	NOVEL polymorphic forms of perindopril (L) -arginine AND PROCESS FOR PREPARATION THEREOF
WO2016178591A2 (en)	2015-05-05	2016-11-10	Gene Predit, Sa	Genetic markers and treatment of male obesity
PH12018502155B1 (en)	2016-04-20	2024-03-27	Servier Lab	Pharmaceutical composition comprising a beta blocker, a converting enzyme inhibitor and an antihypertensive or an nsaid

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2807431B1 (fr) *	2000-04-06	2002-07-19	Adir	Nouveau procede de synthese du perindopril et de ses sels pharmaceutiquement acceptables

2003
- 2003-12-10 DK DK03293084T patent/DK1420029T3/da active
- 2003-12-10 SI SI200331193T patent/SI1420029T1/sl unknown
- 2003-12-10 EP EP03293084A patent/EP1420029B9/de not_active Expired - Lifetime
- 2003-12-10 AT AT03293084T patent/ATE386745T1/de active
- 2003-12-10 DE DE60319196T patent/DE60319196T2/de not_active Expired - Lifetime
- 2003-12-10 ES ES03293084T patent/ES2300555T3/es not_active Expired - Lifetime
- 2003-12-10 PT PT03293084T patent/PT1420029E/pt unknown
2004
- 2004-09-12 UA UAA200607608A patent/UA84898C2/uk unknown
- 2004-12-09 EA EA200601086A patent/EA012034B1/ru not_active IP Right Cessation
- 2004-12-09 ZA ZA200604369A patent/ZA200604369B/en unknown
- 2004-12-09 WO PCT/FR2004/003166 patent/WO2005066198A1/fr not_active Ceased
- 2004-12-09 US US10/582,283 patent/US7279583B2/en not_active Expired - Fee Related
- 2004-12-09 GE GEAP20049501A patent/GEP20084370B/en unknown
- 2004-12-09 BR BRPI0417423A patent/BRPI0417423B1/pt not_active IP Right Cessation
- 2004-12-09 AU AU2004312185A patent/AU2004312185B2/en not_active Ceased
- 2004-12-09 CA CA2548405A patent/CA2548405C/fr not_active Expired - Fee Related
- 2004-12-09 JP JP2006543583A patent/JP4377413B2/ja not_active Expired - Fee Related
- 2004-12-09 NZ NZ547550A patent/NZ547550A/en not_active IP Right Cessation
- 2004-12-09 CN CNB2004800363546A patent/CN100453552C/zh not_active Expired - Fee Related
- 2004-12-09 MY MYPI20045097A patent/MY139289A/en unknown
- 2004-12-09 PL PL380410A patent/PL211485B1/pl unknown
- 2004-12-09 KR KR1020067013586A patent/KR100825537B1/ko not_active Expired - Fee Related
- 2004-12-10 AR ARP040104613A patent/AR047327A1/es not_active Application Discontinuation
2006
- 2006-06-07 MA MA29083A patent/MA28222A1/fr unknown
- 2006-06-28 NO NO20063012A patent/NO20063012L/no not_active Application Discontinuation
2008
- 2008-05-16 CY CY20081100813T patent/CY1108238T1/el unknown

Also Published As

Publication number	Publication date
EP1420029B9 (de)	2008-11-12
CN1890258A (zh)	2007-01-03
DE60319196T2 (de)	2009-04-30
AU2004312185A1 (en)	2005-07-21
NO20063012L (no)	2006-06-28
BRPI0417423A (pt)	2007-03-06
CA2548405A1 (fr)	2005-07-21
BRPI0417423B1 (pt)	2017-03-28
DK1420029T3 (da)	2008-06-16
SI1420029T1 (sl)	2008-08-31
UA84898C2 (uk)	2008-12-10
KR100825537B1 (ko)	2008-04-25
MA28222A1 (fr)	2006-10-02
AU2004312185B2 (en)	2010-09-30
HK1095839A1 (zh)	2007-05-18
JP2008505845A (ja)	2008-02-28
EA200601086A1 (ru)	2006-12-29
MY139289A (en)	2009-09-30
JP4377413B2 (ja)	2009-12-02
WO2005066198A1 (fr)	2005-07-21
DE60319196D1 (de)	2008-04-03
EP1420029B1 (de)	2008-02-20
PT1420029E (pt)	2008-04-14
KR20060097060A (ko)	2006-09-13
CN100453552C (zh)	2009-01-21
EP1420029A2 (de)	2004-05-19
US20070093663A1 (en)	2007-04-26
AR047327A1 (es)	2006-01-18
EP1420029A3 (de)	2004-05-26
ES2300555T3 (es)	2008-06-16
PL380410A1 (pl)	2007-01-22
CY1108238T1 (el)	2014-02-12
PL211485B1 (pl)	2012-05-31
GEP20084370B (en)	2008-05-13
ZA200604369B (en)	2007-11-28
CA2548405C (fr)	2010-07-27
US7279583B2 (en)	2007-10-09
NZ547550A (en)	2009-11-27
EA012034B1 (ru)	2009-06-30

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2008-09-15

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