ATE387208T1 - Antivirale mittel aus pflanzenextrakten und deren verwendung zur behandlung viraler infektionen - Google Patents

Antivirale mittel aus pflanzenextrakten und deren verwendung zur behandlung viraler infektionen

Info

Publication number
ATE387208T1
ATE387208T1 AT97933463T AT97933463T ATE387208T1 AT E387208 T1 ATE387208 T1 AT E387208T1 AT 97933463 T AT97933463 T AT 97933463T AT 97933463 T AT97933463 T AT 97933463T AT E387208 T1 ATE387208 T1 AT E387208T1
Authority
AT
Austria
Prior art keywords
virus
compositions
hepatitis
hiv
treatment
Prior art date
Application number
AT97933463T
Other languages
English (en)
Inventor
Hsiu-Hsien Tsai
Shie-Ming Hwang
Original Assignee
Hsiu-Hsien Tsai
Shie-Ming Hwang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hsiu-Hsien Tsai, Shie-Ming Hwang filed Critical Hsiu-Hsien Tsai
Application granted granted Critical
Publication of ATE387208T1 publication Critical patent/ATE387208T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/638—Ligustrum, e.g. Chinese privet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT97933463T 1996-07-09 1997-07-09 Antivirale mittel aus pflanzenextrakten und deren verwendung zur behandlung viraler infektionen ATE387208T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1610096P 1996-07-09 1996-07-09
US2146796P 1996-07-10 1996-07-10

Publications (1)

Publication Number Publication Date
ATE387208T1 true ATE387208T1 (de) 2008-03-15

Family

ID=26688168

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97933463T ATE387208T1 (de) 1996-07-09 1997-07-09 Antivirale mittel aus pflanzenextrakten und deren verwendung zur behandlung viraler infektionen

Country Status (11)

Country Link
US (3) US5837257A (de)
EP (1) EP0914139B1 (de)
JP (1) JP2001516337A (de)
KR (1) KR100511514B1 (de)
AT (1) ATE387208T1 (de)
AU (1) AU742854B2 (de)
BR (1) BR9710355A (de)
CA (1) CA2271622C (de)
DE (1) DE69738535T2 (de)
ES (1) ES2303342T3 (de)
NZ (1) NZ333707A (de)

Families Citing this family (137)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100346609B1 (ko) * 1994-12-28 2002-11-18 주식회사 엘지씨아이 금은화로부터세코노가노사이드를추출하는방법
US5837257A (en) * 1996-07-09 1998-11-17 Sage R&D Use of plant extracts for treatment of HIV, HCV and HBV infections
KR100239879B1 (ko) * 1997-11-05 2000-02-01 김상조 간암 예방 및 치료용 생약제
US6524625B2 (en) * 1998-06-30 2003-02-25 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyuto Physiologically active extract obtained from indigo plant polygonum tinctorium
US6358060B2 (en) 1998-09-03 2002-03-19 Jsr Llc Two-stage transmucosal medicine delivery system for symptom relief
CA2369448C (en) * 1999-04-14 2008-08-19 Max Zeller Sohne Ag Medicament for inhibiting nf-kb
WO2001003748A1 (en) * 1999-07-13 2001-01-18 Deuk Hun Ahn Herb medicine composition to be spread on sanitary napkin for female
WO2001012228A2 (en) 1999-08-13 2001-02-22 University Of Maryland Biotechnology Institute Compositions for treating viral infections, and methods therefor
US6103242A (en) * 1999-10-21 2000-08-15 Buckley; William Method of controlling blood sugar levels using Coccoloba uvifera
US6337095B1 (en) * 2000-03-30 2002-01-08 Council Of Scientific And Industrial Research Process for the isolation of compound scopoletin useful as nitric oxide synthesis inhibitor
AU2001261744A1 (en) * 2000-05-19 2001-12-03 Npd Llc Chewing gums, lozenges, candies, tablets, liquids, and sprays for efficient delivery of medications and dietary supplements
PY0111577A (es) 2000-05-23 2017-01-02 Idenix Cayman Ltd Métodos y composiciones para el tratamiento del virus de la hepatitis c
US7045159B1 (en) * 2000-09-19 2006-05-16 Rutgers, The State University Of New Jersey Antiviral substances from plant cuticular and epiciticular material
US6696094B2 (en) * 2000-10-18 2004-02-24 Tzu-Sheng Wu Herbal pharmaceutical composition for treatment of HIV/AIDS patients
US6455078B1 (en) * 2000-10-18 2002-09-24 Tzu-Sheng Wu Medicinal herbal composition for treating liver diseases and HIV
CN1309399C (zh) 2000-10-25 2007-04-11 国家中药制药工程技术研究中心 复方双黄连制剂及制备方法
WO2002044717A1 (en) * 2000-12-01 2002-06-06 Cornell Research Foundation Animal model for flaviviridae infection
JP4880816B2 (ja) * 2000-12-15 2012-02-22 株式会社ヤクルト本社 皮膚老化防止剤
US6455070B1 (en) 2001-02-15 2002-09-24 East Park Research, Inc. Composition for treating symptoms of influenza
CN1220498C (zh) * 2001-04-02 2005-09-28 李洪芬 一种治疗哮喘的药剂
US20030054047A1 (en) * 2001-06-15 2003-03-20 Sanjiu Medical & Pharmaceutical Co., Ltd. Pharmaceutical composition for the treatment of viral infection
US20030054978A1 (en) * 2001-08-31 2003-03-20 Babish John G. Arginine compositions for coordinate modification of multiple cardiovascular risk factors
AU2002330154A1 (en) * 2001-09-28 2003-04-07 Centre National De La Recherche Scientifique Methods and compositions for treating hepatitis c virus using 4'-modified nucleosides
WO2003030635A1 (en) * 2001-10-11 2003-04-17 Natural Remedies Private Limited A herbal hepatoprotective and weight gain promoter and a process thereof
US6541045B1 (en) * 2002-01-04 2003-04-01 Nutraceutical Corporation Herbal composition and method for combating inflammation
PT1523489E (pt) 2002-06-28 2014-06-24 Centre Nat Rech Scient Profármacos de nucleósido modificado em 2' e 3' para tratamento de infecções por flaviridae
US7033617B2 (en) * 2002-07-12 2006-04-25 Academia Sinica Use of Anoectochilus formosanus plant extracts and their derived fractions as herbal medicines or nutraceutical supplements for chemoprevention or treatment of human malignancies
AU2003244587B2 (en) * 2002-07-12 2009-06-25 Academia Sinica Use of Anoectochilus Formosanus plant extracts and their derived fractions as herbal medicines or nutraceutical supplements for chemoprevention or treatment of human malignancies
JP2006507235A (ja) * 2002-08-01 2006-03-02 フアーマセツト・インコーポレイテツド フラビウイルス科ウイルス感染治療のためのビシクロ［４．２．１］ノナン系を有する化合物
US20040151787A1 (en) * 2002-11-21 2004-08-05 Pero Ronald W. Water soluble compositions derived from plant material and preparation thereof
US20040126351A1 (en) * 2002-12-26 2004-07-01 Avon Products, Inc. Topical composition having natural skin anti-irritant ingredient and method of use
EP1594524B1 (de) * 2003-01-21 2012-08-15 Novartis Vaccines and Diagnostics, Inc. Verwendung von tryptanthrin-verbindungen zur immunverstärkung
TWI269656B (en) * 2003-03-05 2007-01-01 Original Image Co Ltd Therapeutical composition for hepatitis C
KR101000953B1 (ko) * 2003-05-16 2010-12-13 안경민 비수리 추출물 및 그 용도
US7160561B2 (en) 2003-05-19 2007-01-09 Amazon Biotech Inc. Herbal composition and method of treating HIV infection
US20040234546A1 (en) * 2003-05-19 2004-11-25 Amazon Biotech Inc. Treatments using an herbal composition
BRPI0419345B8 (pt) 2003-05-30 2021-05-25 Gilead Pharmasset Llc uso do (2’r)-2’-desoxi-2’-flúor-2’-c-metil nucleosídeo e de uma composição farmacêutica que o compreende
US7648717B2 (en) * 2003-06-13 2010-01-19 Industrial Technology Research Institute Herbal extract having anti-virus activity and preparation of same
TWI315200B (en) * 2003-06-13 2009-10-01 Ind Tech Res Inst An herbal extract having anti-enterovirus activity and preparation of same
DK1658302T3 (da) 2003-07-25 2010-11-22 Idenix Pharmaceuticals Inc Purinnukleosidanaloge til behandling af sygdomme forårsaget af Flavirividae, herunder hepatitis C
FR2859107B1 (fr) * 2003-08-26 2008-04-18 Oyoubi Pierre Pyebi Utilisation des extraits d'une graminee, d'une rutacee et d'une pieridophyte dans une composition pharmaceutique a activite antivirale, antibacterienne, antifongique et aussi destinee a stimuler les defenses immunitaires
GB0500020D0 (en) 2005-01-04 2005-02-09 Novartis Ag Organic compounds
CN1330359C (zh) * 2004-04-09 2007-08-08 北京琦杰源医药科技发展有限公司 一种治疗艾滋病的中药制剂及其加工方法
SE0400996D0 (sv) * 2004-04-16 2004-04-16 Alltech Ireland Inc Use of plants, plant extracts and nature-identical components from plants to affect the rumen fermentation and to improve the energy and protein retention of ruminants
CN101023094B (zh) 2004-07-21 2011-05-18 法莫赛特股份有限公司 烷基取代的2-脱氧-2-氟代-d-呋喃核糖基嘧啶和嘌呤及其衍生物的制备
US8088757B2 (en) * 2004-09-10 2012-01-03 Biorings Llc Betulinol derivatives as anti-cancer agents
MX2007003085A (es) 2004-09-14 2007-08-02 Pharmasset Inc Preparacion de 2'-fluoro-2'-alquilo sustituido u otras ribofuranosil pirimidinas y purinas opcionalmente sustituidas y sus derivados.
US20060110479A1 (en) * 2004-11-24 2006-05-25 Mitra Shankar K Natural composition for curing hepatitis-B, methods for making the same and pharmaceutical formulations thereof
US7615240B2 (en) * 2005-01-07 2009-11-10 Auburn University Method and composition for the control of gastrointestinal parasites in animals
KR100661032B1 (ko) * 2005-04-19 2006-12-22 주식회사한국야쿠르트 간 기능 개선, 혈중 알코올 감소 및 항산화에 유효한조성물
US7556830B2 (en) * 2005-08-22 2009-07-07 International Patents Holdings, Ltd. Medicinal herbal composition for treating infection
DE202005015707U1 (de) * 2005-10-06 2006-04-20 Sheng Foong Pharmaceutical Co. Ltd., Su-Ao Chen Kräuterzusammensetzung zur Behandlung von Krebs
TWI370739B (en) * 2005-12-30 2012-08-21 Ind Tech Res Inst Herbal compositions of inhibiting free radicals
US8980336B2 (en) * 2005-12-30 2015-03-17 Industrial Technology Research Institute Method for inhibiting free radicals
CA2643680A1 (en) 2006-04-11 2007-11-22 Novartis Ag Hcv/hiv inhibitors and their uses
US8642016B2 (en) 2006-07-21 2014-02-04 Jsrnti, Llc Medicinal delivery system, and related methods
US20080057111A1 (en) * 2006-08-29 2008-03-06 Lixian Jiang Herbal composition for flu prevention and treatment
WO2008088806A1 (en) * 2007-01-16 2008-07-24 Johns Hopkins University Combinational paradigm combating hiv, hiv/hsv, or hiv/hpv infections in humans using small molecular weight compounds from plants
BRPI0808089A2 (pt) 2007-02-28 2014-07-15 Conatus Pharmaceuticals Inc Método para tratar uma doença do fígado, para diminuir um nível elevado de uma enzima do fígado, para inibir uma cascata de sinalização de tnf-alfa e uma cascata de sinalização de alfa-faz, para reduzir um dano ao fígado, para suprimir a apoptose excessiva em uma célula de fígado, e para inibir a replicação do vírus da hepatite c.
US7964580B2 (en) 2007-03-30 2011-06-21 Pharmasset, Inc. Nucleoside phosphoramidate prodrugs
US20090053335A1 (en) * 2007-04-13 2009-02-26 Chih-Hui Lin Herbal compositions for the inhibition of human immunodeficiency virus (hiv)
US20080254148A1 (en) * 2007-04-13 2008-10-16 Gerent Biotech Co. Herbal compositions for the inhibition of human immunodeficiency virus
US8067401B2 (en) * 2007-09-06 2011-11-29 International Patent Holdings Llc Compounds and compositions for treating infection
AU2008296136A1 (en) * 2007-09-07 2009-03-12 Bionovo. Inc. Estrogenic extracts of Scuttelaria barbata D. Don of the Labiatae Family and uses thereof
TW200946541A (en) * 2008-03-27 2009-11-16 Idenix Pharmaceuticals Inc Solid forms of an anti-HIV phosphoindole compound
TWI366466B (en) * 2008-05-08 2012-06-21 Ind Tech Res Inst Herbal extracts capable of inducing immune cells to produce interferon and activating toll-like receptors and the preparation thereof
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
WO2010014134A1 (en) 2008-07-02 2010-02-04 Idenix Pharamaceuticals, Inc. Compounds and pharmaceutical compositions for the treatment of viral infections
JP6104504B2 (ja) 2008-12-23 2017-03-29 ギリアド ファーマセット エルエルシー ヌクレオシド類似体
TW201026715A (en) 2008-12-23 2010-07-16 Pharmasset Inc Nucleoside phosphoramidates
CL2009002206A1 (es) 2008-12-23 2011-08-26 Gilead Pharmasset Llc Compuestos derivados de pirrolo -(2-3-d]-pirimidin-7(6h)-tetrahidrofuran-2-il fosfonamidato, composicion farmaceutica; y su uso en el tratamiento de enfermedades virales.
JP5690286B2 (ja) 2009-03-04 2015-03-25 イデニク プハルマセウティカルス，インコーポレイテッド ホスホチオフェン及びホスホチアゾールｈｃｖポリメラーゼ阻害剤
US8512690B2 (en) 2009-04-10 2013-08-20 Novartis Ag Derivatised proline containing peptide compounds as protease inhibitors
US20110182850A1 (en) 2009-04-10 2011-07-28 Trixi Brandl Organic compounds and their uses
TWI583692B (zh) 2009-05-20 2017-05-21 基利法瑪席特有限責任公司 核苷磷醯胺
US8618076B2 (en) 2009-05-20 2013-12-31 Gilead Pharmasset Llc Nucleoside phosphoramidates
US9284307B2 (en) 2009-08-05 2016-03-15 Idenix Pharmaceuticals Llc Macrocyclic serine protease inhibitors
US20110117055A1 (en) 2009-11-19 2011-05-19 Macdonald James E Methods of Treating Hepatitis C Virus with Oxoacetamide Compounds
JP5651834B2 (ja) * 2009-12-14 2015-01-14 豊勝 堀川 赤血球凝集阻害剤、および赤血球の凝集阻害方法
SG181797A1 (en) 2009-12-18 2012-07-30 Idenix Pharmaceuticals Inc 5,5-fused arylene or heteroarylene hepatitis c virus inhibitors
WO2011080593A2 (en) * 2009-12-30 2011-07-07 Purapharm International (Hk) Limited Materials and methods for prevention and treatment of viral infections
CL2011000716A1 (es) 2010-03-31 2012-04-20 Gilead Pharmasset Llc Formas cristalinas 1 6 de (s)-isopropil-2-(((s)-(((2r.3r.4r.5r)-5-(2,4-dioxo-3,4-dihidropirimidin-1(2h)-il)-4-fluoro-3-hidroxi-4-metil tetrahidrofuran-2-il)metoxi)(fenoxi)fosforil)amino)propanoato; composicion y combinacion farmaceutica; y su uso para tratar una infeccion por el virus de la hepatitis c.
PL3290428T3 (pl) 2010-03-31 2022-02-07 Gilead Pharmasset Llc Tabletka zawierająca krystaliczny (S)-2-(((S)-(((2R,3R,4R,5R)-5-(2,4-diokso-3,4-dihydropirymidyn-1(2H)-ylo)-4-fluoro-3-hydroksy-4-metylotetrahydrofuran-2-ylo)metoksy)(fenoksy)fosforylo)amino)propanian izopropylu
TWI515000B (zh) 2010-04-01 2016-01-01 伊迪尼克製藥公司 用於治療病毒感染之化合物及醫藥組合物
EP2624826B1 (de) 2010-10-08 2018-07-18 Novartis AG Zusammensetzungen enthaltend vitamin e und sulfamide mit ns3 hemmender wirkung
WO2012075140A1 (en) 2010-11-30 2012-06-07 Pharmasset, Inc. Compounds
WO2012080050A1 (en) 2010-12-14 2012-06-21 F. Hoffmann-La Roche Ag Solid forms of a phenoxybenzenesulfonyl compound
KR20120080674A (ko) * 2011-01-08 2012-07-18 주식회사한국전통의학연구소 대계근 추출물을 포함하는 백혈병 치료용 조성물 및 건강 기능성 식품
US8618125B2 (en) 2011-01-14 2013-12-31 Heptiva LLC Composition comprising hepatic therapeutic active for treating liver diseases, certain cancers and liver health maintenance
US9353100B2 (en) 2011-02-10 2016-05-31 Idenix Pharmaceuticals Llc Macrocyclic serine protease inhibitors, pharmaceutical compositions thereof, and their use for treating HCV infections
US20120252721A1 (en) 2011-03-31 2012-10-04 Idenix Pharmaceuticals, Inc. Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
CN103842369A (zh) 2011-03-31 2014-06-04 埃迪尼克斯医药公司 用于治疗病毒感染的化合物和药物组合物
WO2012143017A1 (en) * 2011-04-17 2012-10-26 El-Sawy Mohamed Fakhr El-Din The use of orobancheace extract for the treatment of hepatitis c virus and nonalcoholic fatty liver disease
WO2013039855A1 (en) 2011-09-12 2013-03-21 Idenix Pharmaceuticals, Inc. Compounds and pharmaceutical compositions for the treatment of viral infections
AR088441A1 (es) 2011-09-12 2014-06-11 Idenix Pharmaceuticals Inc Compuestos de carboniloximetilfosforamidato sustituido y composiciones farmaceuticas para el tratamiento de infecciones virales
TW201331221A (zh) 2011-10-14 2013-08-01 Idenix Pharmaceuticals Inc 嘌呤核苷酸化合物類之經取代的３’，５’－環磷酸酯及用於治療病毒感染之醫藥組成物
US8889159B2 (en) 2011-11-29 2014-11-18 Gilead Pharmasset Llc Compositions and methods for treating hepatitis C virus
CA3131037A1 (en) 2011-11-30 2013-06-06 Emory University Antiviral jak inhibitors useful in treating or preventing retroviral and other viral infections
US8809354B2 (en) 2011-12-31 2014-08-19 Sheikh Riazuddin 3-amino-2-(4-nitrophenyl)-4-(3H)-quinazolinone or derivatives thereof for treating or preventing antiviral infections
WO2013133927A1 (en) 2012-02-13 2013-09-12 Idenix Pharmaceuticals, Inc. Pharmaceutical compositions of 2'-c-methyl-guanosine, 5'-[2-[(3-hydroxy-2,2-dimethyl-1-oxopropyl)thio]ethyl n-(phenylmethyl)phosphoramidate]
TWI498118B (zh) * 2012-04-27 2015-09-01 財團法人工業技術研究院 促進傷口癒合及血管新生的醫藥組合物與接骨木屬（蒴藋屬）（Ｓａｍｂｕｃｕｓ）植物及菘藍屬（Ｉｓａｔｉｓ）植物之萃取物用於製備促進傷口癒合及血管新生之藥物的用途
US9296778B2 (en) 2012-05-22 2016-03-29 Idenix Pharmaceuticals, Inc. 3′,5′-cyclic phosphate prodrugs for HCV infection
EP2852604B1 (de) 2012-05-22 2017-04-12 Idenix Pharmaceuticals LLC 3',5'-cyclische phosphoramidat-prodrugs für hcv-infektion
AP3913A (en) 2012-05-22 2016-11-26 Idenix Pharamaceuticals Inc D-amino acid compounds for liver disease
SG11201502750UA (en) 2012-10-08 2015-06-29 Idenix Pharmaceuticals Inc 2'-chloro nucleoside analogs for hcv infection
US20140112886A1 (en) 2012-10-19 2014-04-24 Idenix Pharmaceuticals, Inc. Dinucleotide compounds for hcv infection
EP2909222B1 (de) 2012-10-22 2021-05-26 Idenix Pharmaceuticals LLC 2',4'-verbrückten nukleoside für hcv-infektion
US20140140952A1 (en) 2012-11-14 2014-05-22 Idenix Pharmaceuticals, Inc. D-Alanine Ester of Sp-Nucleoside Analog
EP2920195A1 (de) 2012-11-14 2015-09-23 IDENIX Pharmaceuticals, Inc. D-alaninester eines rp-nukleosidanalogons
EP2935304A1 (de) 2012-12-19 2015-10-28 IDENIX Pharmaceuticals, Inc. 4'-fluor-nukleoside zur behandlung von hcv
US9309275B2 (en) 2013-03-04 2016-04-12 Idenix Pharmaceuticals Llc 3′-deoxy nucleosides for the treatment of HCV
WO2014137930A1 (en) 2013-03-04 2014-09-12 Idenix Pharmaceuticals, Inc. Thiophosphate nucleosides for the treatment of hcv
EP2981542B1 (de) 2013-04-01 2021-09-15 Idenix Pharmaceuticals LLC 2',4'-fluor-nukleoside zur behandlung von hcv
US10005779B2 (en) 2013-06-05 2018-06-26 Idenix Pharmaceuticals Llc 1′,4′-thio nucleosides for the treatment of HCV
WO2015017713A1 (en) 2013-08-01 2015-02-05 Idenix Pharmaceuticals, Inc. D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease
JP2016529293A (ja) 2013-08-27 2016-09-23 ギリアド ファーマセット エルエルシー ２つの抗ウイルス化合物の組合せ製剤
WO2015042375A1 (en) 2013-09-20 2015-03-26 Idenix Pharmaceuticals, Inc. Hepatitis c virus inhibitors
WO2015061683A1 (en) 2013-10-25 2015-04-30 Idenix Pharmaceuticals, Inc. D-amino acid phosphoramidate and d-alanine thiophosphoramidate pronucleotides of nucleoside compounds useful for the treatment of hcv
WO2015066370A1 (en) 2013-11-01 2015-05-07 Idenix Pharmaceuticals, Inc. D-alanine phosphoramidate pronucleotides of 2'-methyl 2'-fluoro guanosine nucleoside compounds for the treatment of hcv
EP3074399A1 (de) 2013-11-27 2016-10-05 Idenix Pharmaceuticals LLC 2'-dichlor- und 2'-fluor-2'-chlor-nukleosidanaloga für hcv-infektion
WO2015094879A1 (en) 2013-12-16 2015-06-25 3M Innovative Properties Company Systems and methods for controlling humidity
EP3083654A1 (de) 2013-12-18 2016-10-26 Idenix Pharmaceuticals LLC 4'-or-nukleoside zur behandlung von hcv
US20170066779A1 (en) 2014-03-05 2017-03-09 Idenix Pharmaceuticals Llc Solid forms of a flaviviridae virus inhibitor compound and salts thereof
WO2015134561A1 (en) 2014-03-05 2015-09-11 Idenix Pharmaceuticals, Inc. Pharmaceutical compositions comprising a 5,5-fused heteroarylene flaviviridae inhibitor and their use for treating or preventing flaviviridae infection
WO2015161137A1 (en) 2014-04-16 2015-10-22 Idenix Pharmaceuticals, Inc. 3'-substituted methyl or alkynyl nucleosides for the treatment of hcv
US9789153B2 (en) 2014-07-02 2017-10-17 Hsiu-Hsien Tsai Composition for preventing cancer and treating cancer and intensifying the effects of other anticancer drugs
CN109917034A (zh) * 2019-03-19 2019-06-21 遵义医科大学 一种白及悬浮培养细胞中2,7-二羟基-4-甲氧基-9,10-二氢菲的定量检测方法
CN110179951A (zh) * 2019-06-28 2019-08-30 宗吉红 一种调治病毒性肝炎的中药组合物及其制备方法
KR102321162B1 (ko) * 2019-11-25 2021-11-02 강원대학교 산학협력단 황백 추출물을 유효성분으로 포함하는 산화아연 저감 사료용 보조제 조성물
EP4259281B1 (de) * 2020-12-14 2025-06-04 Xie Li Products Co., Ltd. Ohwia caudata-extrakte zur verwendung bei der behandlung einer coronavirus-infektion
WO2022174068A1 (en) * 2021-02-12 2022-08-18 Arizona Board Of Regents On Behalf Of Arizona State University Oral botanical composition
KR102607247B1 (ko) * 2021-03-25 2023-11-29 한국식품연구원 도깨비고비 추출물을 유효성분으로 포함하는 항암 조성물
US20210361733A1 (en) * 2021-08-06 2021-11-25 Atta-ur- Rahman Prevention and Treatment of SARS-CoV-2 Infection by Mentha piperita and Flos chrysanthemi Extracts alone, and their Combination
KR102389589B1 (ko) * 2021-09-29 2022-04-22 진지영 야관문 추출물을 포함하는 사료용 항진균성 조성물 및 그의 제조 방법
PL245314B1 (pl) * 2022-07-15 2024-06-24 Inst Chemii Fizycznej Polskiej Akademii Nauk Zastosowanie soli sodowej kwasu 5,5’-indygodisulfonowego do hamowania infekcji bakteriofagowych w procesach biotechnologicznych
US20240148816A1 (en) * 2022-11-07 2024-05-09 King Saud University Herbal composition comprising solanum nigrum for the treatment of cancer
CN117562962B (zh) * 2024-01-15 2024-03-12 四川育强本草生物技术有限公司 美洲大蠊或其提取物的用途及一种治疗猫口炎的中兽药组合物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4808629A (en) * 1985-05-28 1989-02-28 Yaguang Liu Safe antileukemia drug, SAL
JPS6299318A (ja) * 1985-10-25 1987-05-08 Nonogawa Shoji:Kk 養毛剤
US4886666A (en) * 1987-01-27 1989-12-12 Yaguang Liu Pharmaceutical composition for inhibiting viruses and increasing immune function (PII)
US4985248A (en) * 1987-06-18 1991-01-15 Yaguang Liu Pharmaceutical composition containing a safe extracts of fruits and vegetables for the treating and preventing of diabetes
JP2974370B2 (ja) * 1990-05-11 1999-11-10 社団法人北里研究所 シアリダーゼ阻害剤
JPH0426650A (ja) * 1990-05-17 1992-01-29 Kuraray Co Ltd オレアノール酸の製造法
US5178865A (en) * 1990-06-19 1993-01-12 Cedars-Sinai Medical Center Chinese herbal extracts in the treatment of hiv related disease in vitro
US5366725A (en) * 1990-06-27 1994-11-22 Shinya Okubo Method for the treatment of cancer
CN1077379A (zh) * 1992-04-16 1993-10-20 张笑平 乙肝表面抗原转阴冲剂及其制备方法
US5411733A (en) * 1992-04-27 1995-05-02 Hozumi; Toyoharu Antiviral agent containing crude drug
CN1049338C (zh) * 1993-03-20 2000-02-16 赵三立 治疗乙型肝炎的药液
JP3183754B2 (ja) * 1993-07-20 2001-07-09 ポーラ化成工業株式会社 動脈硬化抑制剤及びこれを含有する組成物
US5837257A (en) * 1996-07-09 1998-11-17 Sage R&D Use of plant extracts for treatment of HIV, HCV and HBV infections

Also Published As

Publication number Publication date
WO1998001144A1 (en) 1998-01-15
EP0914139B1 (de) 2008-02-27
AU3664297A (en) 1998-02-02
US5989556A (en) 1999-11-23
DE69738535D1 (de) 2008-04-10
ES2303342T3 (es) 2008-08-01
KR100511514B1 (ko) 2005-08-31
BR9710355A (pt) 2000-01-11
DE69738535T2 (de) 2009-02-19
AU742854B2 (en) 2002-01-17
EP0914139A2 (de) 1999-05-12
CA2271622A1 (en) 1998-01-15
CA2271622C (en) 2002-12-17
US6214350B1 (en) 2001-04-10
NZ333707A (en) 2000-09-29
US5837257A (en) 1998-11-17
JP2001516337A (ja) 2001-09-25
KR20000023648A (ko) 2000-04-25

Similar Documents

Publication Publication Date Title
DE69738535D1 (de) Antivirale mittel aus pflanzenextrakten und deren verwendung zur behandlung viraler infektionen
ATE264914T1 (de) Antivirale proteine, dafür kodierende dna, und deren verwendung
WO2003051306A3 (en) N4-acylcytosine-1,3-dioxolane nucleosides for treatment of viral infections
DE60229677D1 (de) Langwirkende Fusionspeptidinhibitoren gegen HIV-Infektion
ATE219366T1 (de) Verwendung von 5-fluoro-2'-deoxy-3'-thiacytidin zur behandlung von hepatitis b
DK0980203T3 (da) Antimikrobiel forebyggelse og behandling af humant immundeficiensvirus og andre infektiöse sygdomme
WO2001010456A3 (en) Peptides that block viral infectivity and methods of use thereof
ES2187530T3 (es) Peptidos para reducir respuestas de linfocito t ctitotoxicos al virus de la hepatitis b.
GEP20084377B (en) Agent for inhibiting membrane virus reproduction, method for the production thereof, pharmaceutical composition and method for inhibiting viral infections
ATE152717T1 (de) Gegen viren wirksame naphtochinon-verbindungen, zusammensetzungen und deren verwendungen
ES2105923A1 (es) Composiciones para el tratamiento de una infeccion y una enfermedad causadas por el virus de la hepatitis b (hbv).
MY157594A (en) Compositions of matter useful in the treatment of viral infections derived from plant extracts
AU2880595A (en) Use of pharmaceutical agents for restoring, alleviation, or treatment of immunodeficiency, including the alleviation or treatment of the immune dysfunction related to infection with human immunodeficiency viruses (hiv) or related viruses
WO1998001144A2 (en) Antiviral agents from plant extracts and use for treatment of viral infections
RU93058325A (ru) Применение производных 1,3-оксатиолана для получения лекарственных препаратов для лечения или профилактики вирусной инфекции гепатита в, применение производных 1,3 - оксатиолана для лечения инфекций гепатита в, способ лечения гепатита в
CA2401295A1 (en) Process for preparing an anti viral medicinal product from plant extracts
BG101175A (bg) Тройна анти-нiv комбинация
UA41338C2 (uk) Спосіб інгібування ретровірусної інфекції, яка викликана вірусом імунодефіциту людини (віл), спосіб інгібування вірусу імунодефіциту людини (віл)
KR950702838A (ko) 인터루킨-4(IL-4)를 사용한 사람 면역결핍 바이러스(HIV) 복제의 억제방법(Method for inhibiting HIV replication using IL-4)
EP0963441A4 (de) Inaktivierung von hiv ko-rezeptoren zur therapie der hiv-infektion
WO2001030325A3 (en) Use of a bis-peroxovanadium compound for the treatment of immunosuppressed patients
BR0207931A (pt) Anticorpos naturais ativos contra vìrus hiv
DE69422980D1 (de) Extrakte von Piliostigma thonningii, deren Verwendung und diese enthaltende Zubereitungen
BR0008269A (pt) Uso de uma preparação de m. vaccae, e, método para tratamento de infecção viral crÈnica, excluindo infecção por hiv
WO2002009677A3 (en) Method to treat infectious diseases and/or to enhance antimicrobial efficacy of drugs

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties