ATE389388T1 - Zusammensetzungen mit verzoegerter freisetzung und verfahren zu deren herstellung - Google Patents
Zusammensetzungen mit verzoegerter freisetzung und verfahren zu deren herstellungInfo
- Publication number
- ATE389388T1 ATE389388T1 AT98921551T AT98921551T ATE389388T1 AT E389388 T1 ATE389388 T1 AT E389388T1 AT 98921551 T AT98921551 T AT 98921551T AT 98921551 T AT98921551 T AT 98921551T AT E389388 T1 ATE389388 T1 AT E389388T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- sustained release
- release compositions
- compositions
- sustained
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 238000013268 sustained release Methods 0.000 title 1
- 239000012730 sustained-release form Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
- Y10T428/2985—Solid-walled microcapsule from synthetic polymer
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9704837A FR2762318B1 (fr) | 1997-04-18 | 1997-04-18 | Compositions presentant une liberation prolongee et leur procede de preparation |
| FR9803666A FR2776516B1 (fr) | 1998-03-25 | 1998-03-25 | Compositions presentant une liberation prolongee et leur procede de preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE389388T1 true ATE389388T1 (de) | 2008-04-15 |
Family
ID=26233477
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98921551T ATE389388T1 (de) | 1997-04-18 | 1998-04-17 | Zusammensetzungen mit verzoegerter freisetzung und verfahren zu deren herstellung |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US6217893B1 (de) |
| EP (1) | EP0980240B1 (de) |
| JP (1) | JP4557312B2 (de) |
| CN (2) | CN1313082C (de) |
| AR (2) | AR012448A1 (de) |
| AT (1) | ATE389388T1 (de) |
| AU (1) | AU741964B2 (de) |
| BR (1) | BR9808933A (de) |
| CA (1) | CA2286575C (de) |
| CZ (1) | CZ297078B6 (de) |
| DE (1) | DE69839264T2 (de) |
| DK (1) | DK0980240T3 (de) |
| ES (1) | ES2303353T3 (de) |
| HU (1) | HUP0004297A2 (de) |
| IL (1) | IL132217A (de) |
| MY (1) | MY118835A (de) |
| NO (2) | NO327999B1 (de) |
| PL (1) | PL196771B1 (de) |
| PT (1) | PT980240E (de) |
| RU (1) | RU2198678C2 (de) |
| TW (1) | TW577759B (de) |
| WO (1) | WO1998047489A1 (de) |
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| AR012448A1 (es) * | 1997-04-18 | 2000-10-18 | Ipsen Pharma Biotech | Composicion en forma de microcapsulas o de implantes que comprende un excipiente biodegradable, polimero o co-polimero, o una mezcla de talesexcipientes, y una sustancia activa o una mezcla de sustancias activas, procedimiento para la preparacion de una sustancia soluble en agua de elevada |
| US6303138B1 (en) | 1999-09-17 | 2001-10-16 | Depuy Orthopaedics | Endothelin-based compositions for enhancing connective tissue repair |
| EP1274720A4 (de) * | 2000-04-12 | 2004-08-18 | Human Genome Sciences Inc | Albumin enthaltende fusionsproteine |
| US6824822B2 (en) * | 2001-08-31 | 2004-11-30 | Alkermes Controlled Therapeutics Inc. Ii | Residual solvent extraction method and microparticles produced thereby |
| CA2444518A1 (en) * | 2001-04-17 | 2002-10-24 | University Of Sheffield | Biomaterials comprising a melanocyte stimulating hormone (msh), and method of forming |
| WO2002097038A2 (en) * | 2001-05-25 | 2002-12-05 | Human Genome Sciences, Inc. | Chemokine beta-1 fusion proteins |
| KR101320817B1 (ko) * | 2001-06-01 | 2013-10-21 | 노파르티스 아게 | 부갑상선 호르몬 및 칼시토닌의 경구 투여 |
| CA2451187C (en) | 2001-06-22 | 2012-08-14 | Southern Biosystems, Inc. | Zero-order prolonged release coaxial implants |
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| PT1463751E (pt) | 2001-12-21 | 2013-08-26 | Human Genome Sciences Inc | Proteínas de fusão de albumina |
| EP1463752A4 (de) * | 2001-12-21 | 2005-07-13 | Human Genome Sciences Inc | Albuminfusionsproteine |
| RU2252753C2 (ru) * | 2002-05-15 | 2005-05-27 | Ооо Мако | Готовая лекарственная форма инсулина человека пролонгированного действия |
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| US20040097419A1 (en) * | 2002-11-19 | 2004-05-20 | Holger Petersen | Organic compounds |
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| CA2513213C (en) | 2003-01-22 | 2013-07-30 | Human Genome Sciences, Inc. | Albumin fusion proteins |
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| CA2552241C (en) * | 2003-12-30 | 2013-10-01 | Durect Corporation | Co-polymeric devices for controlled release of active agents |
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| CN104394980B (zh) | 2012-03-08 | 2018-10-09 | 康斯乔最高科学研究公司 | 具有光致变色性质的涂层、产生所述涂层的方法及其适用于光学制品和光滑表面的用途 |
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| BR112019017724A2 (pt) | 2017-03-26 | 2020-03-31 | Mapi Pharma Ltd. | Sistemas depot de glatiramer para tratar formas progressivas de esclerose múltipla |
| CN107375910B (zh) * | 2017-07-12 | 2020-03-24 | 温州医科大学附属第二医院、温州医科大学附属育英儿童医院 | PTHrP在制备治疗男性性腺功能低下综合征中的应用 |
| CN110547969A (zh) * | 2019-09-03 | 2019-12-10 | 杭州诺泰澳赛诺医药技术开发有限公司 | 一种高比表面积纳米级缓释微粉的生产工艺及设备 |
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| FR2693905B1 (fr) | 1992-07-27 | 1994-09-02 | Rhone Merieux | Procédé de préparation de microsphères pour la libération prolongée de l'hormone LHRH et ses analogues, microsphères et formulations obtenues. |
| JPH08505395A (ja) * | 1993-01-06 | 1996-06-11 | キナートン リミティド | 生物分解性ポリエステルと生物活性ポリペプチドのイオン分子結合体 |
| US5785976A (en) * | 1993-03-05 | 1998-07-28 | Pharmacia & Upjohn Ab | Solid lipid particles, particles of bioactive agents and methods for the manufacture and use thereof |
| US6117455A (en) | 1994-09-30 | 2000-09-12 | Takeda Chemical Industries, Ltd. | Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent |
| KR19980703876A (ko) * | 1995-04-14 | 1998-12-05 | 스티븐 엘. 허스트 | 분산성이 개선된 분말화된 약학적 조성물 |
| WO1996040072A2 (en) * | 1995-06-07 | 1996-12-19 | Alkermes Controlled Therapeutics, Inc. | Composition for sustained release of human growth hormone |
| AR012448A1 (es) * | 1997-04-18 | 2000-10-18 | Ipsen Pharma Biotech | Composicion en forma de microcapsulas o de implantes que comprende un excipiente biodegradable, polimero o co-polimero, o una mezcla de talesexcipientes, y una sustancia activa o una mezcla de sustancias activas, procedimiento para la preparacion de una sustancia soluble en agua de elevada |
-
1998
- 1998-04-16 AR ARP980101756A patent/AR012448A1/es not_active Application Discontinuation
- 1998-04-16 MY MYPI98001698A patent/MY118835A/en unknown
- 1998-04-16 TW TW087105802A patent/TW577759B/zh not_active IP Right Cessation
- 1998-04-17 RU RU99124209/14A patent/RU2198678C2/ru not_active IP Right Cessation
- 1998-04-17 BR BR9808933-1A patent/BR9808933A/pt not_active Application Discontinuation
- 1998-04-17 CZ CZ0362699A patent/CZ297078B6/cs not_active IP Right Cessation
- 1998-04-17 EP EP98921551A patent/EP0980240B1/de not_active Revoked
- 1998-04-17 JP JP54515098A patent/JP4557312B2/ja not_active Expired - Fee Related
- 1998-04-17 AT AT98921551T patent/ATE389388T1/de active
- 1998-04-17 HU HU0004297A patent/HUP0004297A2/hu unknown
- 1998-04-17 ES ES98921551T patent/ES2303353T3/es not_active Expired - Lifetime
- 1998-04-17 CN CNB031545998A patent/CN1313082C/zh not_active Expired - Fee Related
- 1998-04-17 CA CA2286575A patent/CA2286575C/fr not_active Expired - Fee Related
- 1998-04-17 DK DK98921551T patent/DK0980240T3/da active
- 1998-04-17 PL PL336296A patent/PL196771B1/pl unknown
- 1998-04-17 DE DE69839264T patent/DE69839264T2/de not_active Expired - Lifetime
- 1998-04-17 PT PT98921551T patent/PT980240E/pt unknown
- 1998-04-17 US US09/403,058 patent/US6217893B1/en not_active Expired - Lifetime
- 1998-04-17 CN CNB988052202A patent/CN1144584C/zh not_active Expired - Fee Related
- 1998-04-17 WO PCT/FR1998/000773 patent/WO1998047489A1/fr not_active Ceased
- 1998-04-17 IL IL13221798A patent/IL132217A/en not_active IP Right Cessation
- 1998-04-17 AU AU74363/98A patent/AU741964B2/en not_active Ceased
-
1999
- 1999-10-15 NO NO19995063A patent/NO327999B1/no not_active IP Right Cessation
-
2000
- 2000-11-06 US US09/707,372 patent/US6475507B1/en not_active Expired - Lifetime
-
2007
- 2007-07-05 AR ARP070102999A patent/AR061828A2/es not_active Application Discontinuation
-
2008
- 2008-02-14 NO NO20080803A patent/NO20080803L/no not_active Application Discontinuation
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