ATE391725T1 - Kristallstruktur von menschlichem il-18 - Google Patents

Kristallstruktur von menschlichem il-18

Info

Publication number
ATE391725T1
ATE391725T1 AT03719821T AT03719821T ATE391725T1 AT E391725 T1 ATE391725 T1 AT E391725T1 AT 03719821 T AT03719821 T AT 03719821T AT 03719821 T AT03719821 T AT 03719821T AT E391725 T1 ATE391725 T1 AT E391725T1
Authority
AT
Austria
Prior art keywords
human
crystal structure
identified
crystalline structure
novel human
Prior art date
Application number
AT03719821T
Other languages
English (en)
Inventor
Cheryl JANSON
Nestor Concha
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of ATE391725T1 publication Critical patent/ATE391725T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Laminated Bodies (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT03719821T 2002-04-17 2003-04-17 Kristallstruktur von menschlichem il-18 ATE391725T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37329302P 2002-04-17 2002-04-17

Publications (1)

Publication Number Publication Date
ATE391725T1 true ATE391725T1 (de) 2008-04-15

Family

ID=29251010

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03719821T ATE391725T1 (de) 2002-04-17 2003-04-17 Kristallstruktur von menschlichem il-18

Country Status (8)

Country Link
US (1) US7253260B2 (de)
EP (1) EP1573032B1 (de)
JP (1) JP2006508029A (de)
AT (1) ATE391725T1 (de)
AU (1) AU2003222627A1 (de)
DE (1) DE60320304T2 (de)
ES (1) ES2303899T3 (de)
WO (1) WO2003089653A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI335336B (de) * 2000-02-10 2011-01-01 Abbott Gmbh & Co Kg
US20060177871A1 (en) * 2002-08-13 2006-08-10 Janson Cheryl A Murine IL-18 crystal structure
ATE459647T1 (de) 2003-04-15 2010-03-15 Glaxosmithkline Llc Humane il-18 substitutionsmutanten und deren konjugate
US7968684B2 (en) * 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
CN111315395A (zh) 2017-09-06 2020-06-19 耶鲁大学 白细胞介素-18变体和使用方法
US12029778B2 (en) 2019-05-13 2024-07-09 Yale University Interleukin-18 mimics and methods of use
JP2025508823A (ja) 2022-02-23 2025-04-10 ブライト ピーク セラピューティクス エージー 免疫抗原特異的ｉｌ－１８免疫サイトカイン及びその使用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192324A (en) * 1982-02-18 1993-03-09 Howmedica Inc. Bone prosthesis with porous coating
AU1270592A (en) 1991-02-05 1992-09-07 University Of Maryland Modified interleukin-1beta
DE69519454T2 (de) * 1994-07-14 2001-05-03 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo, Okayama Protein, das Interferon-Gamma Herstellung induziert und monoklonaler Antikörper dagegen
US6207641B1 (en) * 1995-03-10 2001-03-27 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Pharmaceutical composition containing IFN-γ inducing polypeptide or factor for treating and/or preventing IFN-γ susceptive diseases
JP2724987B2 (ja) * 1994-11-15 1998-03-09 株式会社林原生物化学研究所 インターフェロン−γの産生を誘導するポリペプチド
JP2952750B2 (ja) * 1995-02-23 1999-09-27 株式会社林原生物化学研究所 モノクローナル抗体
TWI335336B (de) 2000-02-10 2011-01-01 Abbott Gmbh & Co Kg
WO2003057821A2 (en) 2001-10-26 2003-07-17 Centocor, Inc. Mut-il-18 or mut-il-18r proteins, antibodies, compositions, methods and uses

Also Published As

Publication number Publication date
WO2003089653A3 (en) 2005-12-15
US7253260B2 (en) 2007-08-07
JP2006508029A (ja) 2006-03-09
EP1573032B1 (de) 2008-04-09
WO2003089653A2 (en) 2003-10-30
DE60320304T2 (de) 2009-05-20
DE60320304D1 (de) 2008-05-21
EP1573032A4 (de) 2006-06-21
US20030232032A1 (en) 2003-12-18
EP1573032A2 (de) 2005-09-14
AU2003222627A1 (en) 2003-11-03
ES2303899T3 (es) 2008-09-01

Similar Documents

Publication Publication Date Title
ATE520674T1 (de) Natriumkanalblocker
ATE442364T1 (de) Kristalline form von linezolid
ATE490253T1 (de) Synthese von 5-substituierten 7-azaindolen und 7- azaindolinen
ATE461217T1 (de) Glp-1-verbindungen
NO20045529L (no) Substituerte heterocykliske derivater hvilke er anvendelige som antidiabetes- og antiovervektsmidler og metode
DE60312412D1 (de) Medizinische Elektroden
FI20021262A0 (fi) Sokerien kiteytys
DE60324178D1 (de) THIAZOLIDIN-4-ONES UM hYAK3 PROTEINEN ZU HEMMEN
DK1668001T3 (da) Substituerede heteroarylbenzofuransyrer
UY3375Q (es) Esponja
DK1572229T3 (da) Stabilt terapeutisk fibrinogen
EA200700702A1 (ru) Аналоги локсапина и способы их применения
ATE391725T1 (de) Kristallstruktur von menschlichem il-18
ITMI20031797A1 (it) Procedimento e dispositivo per evitare spostamenti della
TNSN06138A1 (fr) Inhibitors of the mutant form of kit
DK1558580T3 (da) N-sulfonyl-4-methylenamino-3-hydroxy-2-pyridoner
DE50311406D1 (de) Verwendung von Formkörpern
DK1644385T3 (da) Siliciumforbindelser og deres anvendelse
ATE474824T1 (de) Herstellung von olefinen
DE60330315D1 (de) Acylfluorid-aktivierung von mit carboxysilyl beschichteten glassubstraten
DK1648906T3 (da) Organo-silicium-forbindelser og deres anvendelse
DE60326437D1 (de) Therapeutische verwendung von sapogeninen
EA200000946A1 (ru) Кристаллическая форма пароксетина
DE602004016959D1 (de) Kristallmodifikationen von triazinylaminostilbenen
DE60222939D1 (de) Festkörper-synthese von lithium-meta-arsenit

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties