ATE391725T1 - Kristallstruktur von menschlichem il-18 - Google Patents

Kristallstruktur von menschlichem il-18

Info

Publication number
ATE391725T1
ATE391725T1 AT03719821T AT03719821T ATE391725T1 AT E391725 T1 ATE391725 T1 AT E391725T1 AT 03719821 T AT03719821 T AT 03719821T AT 03719821 T AT03719821 T AT 03719821T AT E391725 T1 ATE391725 T1 AT E391725T1
Authority
AT
Austria
Prior art keywords
human
crystal structure
identified
crystalline structure
novel human
Prior art date
Application number
AT03719821T
Other languages
English (en)
Inventor
Cheryl JANSON
Nestor Concha
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of ATE391725T1 publication Critical patent/ATE391725T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Laminated Bodies (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT03719821T 2002-04-17 2003-04-17 Kristallstruktur von menschlichem il-18 ATE391725T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37329302P 2002-04-17 2002-04-17

Publications (1)

Publication Number Publication Date
ATE391725T1 true ATE391725T1 (de) 2008-04-15

Family

ID=29251010

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03719821T ATE391725T1 (de) 2002-04-17 2003-04-17 Kristallstruktur von menschlichem il-18

Country Status (8)

Country Link
US (1) US7253260B2 (de)
EP (1) EP1573032B1 (de)
JP (1) JP2006508029A (de)
AT (1) ATE391725T1 (de)
AU (1) AU2003222627A1 (de)
DE (1) DE60320304T2 (de)
ES (1) ES2303899T3 (de)
WO (1) WO2003089653A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2399148A1 (en) * 2000-02-10 2001-08-16 Abbott Laboratories Antibodies that bind human interleukin-18 and methods of making and using
US20060177871A1 (en) * 2002-08-13 2006-08-10 Janson Cheryl A Murine IL-18 crystal structure
EP2261244A3 (de) 2003-04-15 2011-02-23 Glaxosmithkline LLC Humane IL-18 Substitutionsmutanten und deren Konjugate
US7968684B2 (en) 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
IL272635B2 (en) 2017-09-06 2024-02-01 Univ Yale Variants of interleukin-18 and methods of use
US12029778B2 (en) 2019-05-13 2024-07-09 Yale University Interleukin-18 mimics and methods of use
AU2023226512A1 (en) 2022-02-23 2024-08-29 Bright Peak Therapeutics Ag Immune antigen specific il-18 immunocytokines and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5192324A (en) * 1982-02-18 1993-03-09 Howmedica Inc. Bone prosthesis with porous coating
AU1270592A (en) 1991-02-05 1992-09-07 University Of Maryland Modified interleukin-1beta
DE69519454T2 (de) * 1994-07-14 2001-05-03 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo, Okayama Protein, das Interferon-Gamma Herstellung induziert und monoklonaler Antikörper dagegen
JP2724987B2 (ja) * 1994-11-15 1998-03-09 株式会社林原生物化学研究所 インターフェロン−γの産生を誘導するポリペプチド
JP2952750B2 (ja) * 1995-02-23 1999-09-27 株式会社林原生物化学研究所 モノクローナル抗体
US6207641B1 (en) * 1995-03-10 2001-03-27 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Pharmaceutical composition containing IFN-γ inducing polypeptide or factor for treating and/or preventing IFN-γ susceptive diseases
CA2399148A1 (en) 2000-02-10 2001-08-16 Abbott Laboratories Antibodies that bind human interleukin-18 and methods of making and using
US20040023336A1 (en) 2001-10-26 2004-02-05 Heavner George A. Mut-IL-18 or Mut-IL-18R proteins, antibodies, compositions, methods and uses

Also Published As

Publication number Publication date
WO2003089653A2 (en) 2003-10-30
JP2006508029A (ja) 2006-03-09
DE60320304D1 (de) 2008-05-21
ES2303899T3 (es) 2008-09-01
DE60320304T2 (de) 2009-05-20
AU2003222627A1 (en) 2003-11-03
US7253260B2 (en) 2007-08-07
EP1573032A2 (de) 2005-09-14
EP1573032B1 (de) 2008-04-09
EP1573032A4 (de) 2006-06-21
WO2003089653A3 (en) 2005-12-15
US20030232032A1 (en) 2003-12-18

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Legal Events

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