ATE394473T1 - Fermentationsverfahren mit geringer zelldichte zur produktion heterologer rekombinanter proteine in mikroorganismen - Google Patents

Fermentationsverfahren mit geringer zelldichte zur produktion heterologer rekombinanter proteine in mikroorganismen

Info

Publication number
ATE394473T1
ATE394473T1 AT04821402T AT04821402T ATE394473T1 AT E394473 T1 ATE394473 T1 AT E394473T1 AT 04821402 T AT04821402 T AT 04821402T AT 04821402 T AT04821402 T AT 04821402T AT E394473 T1 ATE394473 T1 AT E394473T1
Authority
AT
Austria
Prior art keywords
production
fermentation
cell density
feed medium
microorganisms
Prior art date
Application number
AT04821402T
Other languages
English (en)
Inventor
Milind Prabhakar Usv Niphadkar
Genevieve Suzie Nazareth
Neelesh Ramesh Surlikar
Monsur Ahmed Borbhuiya
Uma Sankararaman
Dipanwita Maiti
Laxmi Rao
Saptarshi Paul
Shrikant Mishra
Original Assignee
Usv Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Usv Ltd filed Critical Usv Ltd
Application granted granted Critical
Publication of ATE394473T1 publication Critical patent/ATE394473T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT04821402T 2004-12-21 2004-12-21 Fermentationsverfahren mit geringer zelldichte zur produktion heterologer rekombinanter proteine in mikroorganismen ATE394473T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IN2004/000393 WO2006067793A1 (en) 2004-12-21 2004-12-21 Low cell density fermentation process for the production of heterologous recombinant proteins in microorganisms

Publications (1)

Publication Number Publication Date
ATE394473T1 true ATE394473T1 (de) 2008-05-15

Family

ID=36601439

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04821402T ATE394473T1 (de) 2004-12-21 2004-12-21 Fermentationsverfahren mit geringer zelldichte zur produktion heterologer rekombinanter proteine in mikroorganismen

Country Status (8)

Country Link
US (2) US20100047870A1 (de)
EP (1) EP1828375B1 (de)
AT (1) ATE394473T1 (de)
AU (1) AU2004325822A1 (de)
BR (1) BRPI0419235A (de)
CA (1) CA2589716A1 (de)
DE (1) DE602004013648D1 (de)
WO (1) WO2006067793A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1885847B1 (de) * 2005-05-26 2011-07-06 Cytos Biotechnology AG Skalierbares fermentationsverfahren
RU2592671C2 (ru) 2010-09-21 2016-07-27 Ферринг Б.В. Улучшенный способ получения рекомбинантного человеческого гормона роста
DK2732024T3 (en) 2011-07-13 2017-05-22 Foodchek Systems Inc CULTURE MEDIUM, METHOD FOR CULTIVATING LISTERIA, AND METHOD FOR DETERMINING LISTERIA
CN109504714B (zh) * 2017-09-15 2022-04-12 北京蓝晶微生物科技有限公司 一种无灭菌发酵生产聚羟基脂肪酸酯的方法
CN114015628A (zh) * 2021-12-17 2022-02-08 河南兴华生物技术有限公司 表达pmt蛋白的培养基及培养方法
CN120699876B (zh) * 2025-08-14 2026-03-06 天津中合基因科技有限公司 一种发酵末端脱氧核苷酸转移酶的培养基及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5595905A (en) * 1992-03-12 1997-01-21 G.D. Searle & Co. Process control system for fed-batch fermentation using a computer to predict nutrient consumption
DE4337787A1 (de) * 1993-11-05 1995-05-11 Hoechst Ag Sauerstoffabhängige Fermentation von Mikroorganismen
SE9904502D0 (sv) * 1999-12-09 1999-12-09 Pharmacia & Upjohn Ab Production of peptides
US6955892B2 (en) * 2002-11-12 2005-10-18 Akzo Nobel N.V. Feeding processes for fermentation

Also Published As

Publication number Publication date
DE602004013648D1 (de) 2008-06-19
WO2006067793A1 (en) 2006-06-29
EP1828375B1 (de) 2008-05-07
US20110189733A1 (en) 2011-08-04
EP1828375A1 (de) 2007-09-05
US20100047870A1 (en) 2010-02-25
AU2004325822A1 (en) 2006-06-29
CA2589716A1 (en) 2006-06-29
BRPI0419235A (pt) 2007-12-18

Similar Documents

Publication Publication Date Title
Aristidou et al. Metabolic engineering of Escherichia coli to enhance recombinant protein production through acetate reduction
Park et al. Enhanced β‐galactosidase production by high cell‐density culture of recombinant Bacillus subtilis with glucose concentration control
Panda et al. Kinetics of inclusion body production in batch and high cell density fed-batch culture of Escherichia coli expressing ovine growth hormone
MacDonald et al. Effects of medium quality on the expression of human interleukin-2 at high cell density in fermentor cultures of Escherichia coli K-12
KR102036671B1 (ko) 대장균의 고농도 배양방법
US7521203B2 (en) Feeding processes for fermentation
EP1689875B2 (de) Herstellung von amiden
CN119654420A (zh) 使用芽孢杆菌宿主细胞的稳定的蛋白质生产方法
CN116157530A (zh) 使用温度变化的芽孢杆菌工业发酵工艺
Vuolanto et al. Phytase production by high cell density culture of recombinant Bacillus subtilis
Kim et al. Continuous glutamate production using an immobilized whole‐cell system
ATE394473T1 (de) Fermentationsverfahren mit geringer zelldichte zur produktion heterologer rekombinanter proteine in mikroorganismen
US5139938A (en) Production of substances with an acetic acid-producing and assimilating bacterium inhibited by acetic acid
CN118792234B (zh) 一种增强secD和ftsY基因转录水平的谷氨酰胺转氨酶高产菌株及其制备方法
CN1254545C (zh) 蛋白质的生产方法
Nakagawa et al. High cell density cultivation and high recombinant protein production of Escherichia coli strain expressing uricase
WO1999061633A3 (en) Method for the isolation of ccc plasmid dna
KR20230042509A (ko) 공급 속도 이동을 이용한 바실러스의 산업적 발효 방법
Lee et al. Mass production of thermostable D‐hydantoinase by batch culture of recombinant Escherichia coli with a constitutive expression system
KR20120011261A (ko) 바실러스속 균주의 유가식 배양 방법에 의한 나토키나아제 대량 생산 방법
Tulin et al. Effective extracellular production of Bacillus stearothermophilus esterase by pH‐stat modal fed‐batch culture of recombinant Bacillus brevis
Delacruz et al. Bioprocess development to improve foreign protein production from recombinant Streptomyces
Brandes et al. Fed‐batch cultivation of recombinant Escherichia coli JM103 and production of the fusion protein SPA:: EcoRI in a 60‐L working volume airlift tower loop reactor
CN116286583A (zh) 一种能高效分解单氰胺和氧化亚磷酸盐的重组枯草芽孢杆菌及其构建方法与应用
JP3239903B2 (ja) エシェリヒア・コリによる新規l−スレオニン生産菌の創成とそれによるl−スレオニンの生産方法

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties