ATE395603T1 - Reagenziensatz zum nachweis von lupus- antikoagulant. - Google Patents
Reagenziensatz zum nachweis von lupus- antikoagulant.Info
- Publication number
- ATE395603T1 ATE395603T1 AT05002403T AT05002403T ATE395603T1 AT E395603 T1 ATE395603 T1 AT E395603T1 AT 05002403 T AT05002403 T AT 05002403T AT 05002403 T AT05002403 T AT 05002403T AT E395603 T1 ATE395603 T1 AT E395603T1
- Authority
- AT
- Austria
- Prior art keywords
- phosphatidylethanolamine
- time measurement
- detection
- coagulation time
- lupus anticoagulant
- Prior art date
Links
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 6
- 239000003146 anticoagulant agent Substances 0.000 title abstract 2
- 229940127219 anticoagulant drug Drugs 0.000 title abstract 2
- 206010025135 lupus erythematosus Diseases 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title 1
- JZNWSCPGTDBMEW-UHFFFAOYSA-N Glycerophosphorylethanolamin Natural products NCCOP(O)(=O)OCC(O)CO JZNWSCPGTDBMEW-UHFFFAOYSA-N 0.000 abstract 4
- 230000015271 coagulation Effects 0.000 abstract 4
- 238000005345 coagulation Methods 0.000 abstract 4
- 238000005259 measurement Methods 0.000 abstract 4
- 150000008104 phosphatidylethanolamines Chemical class 0.000 abstract 4
- TZCPCKNHXULUIY-RGULYWFUSA-N 1,2-distearoyl-sn-glycero-3-phosphoserine Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OC[C@H](N)C(O)=O)OC(=O)CCCCCCCCCCCCCCCCC TZCPCKNHXULUIY-RGULYWFUSA-N 0.000 abstract 2
- ZWZWYGMENQVNFU-UHFFFAOYSA-N Glycerophosphorylserin Natural products OC(=O)C(N)COP(O)(=O)OCC(O)CO ZWZWYGMENQVNFU-UHFFFAOYSA-N 0.000 abstract 2
- 150000003904 phospholipids Chemical class 0.000 abstract 2
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
- G01N2405/04—Phospholipids, i.e. phosphoglycerides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004031372 | 2004-02-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE395603T1 true ATE395603T1 (de) | 2008-05-15 |
Family
ID=34675576
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05002403T ATE395603T1 (de) | 2004-02-06 | 2005-02-04 | Reagenziensatz zum nachweis von lupus- antikoagulant. |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20050175983A1 (de) |
| EP (1) | EP1562047B1 (de) |
| AT (1) | ATE395603T1 (de) |
| DE (1) | DE602005006633D1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7932021B2 (en) * | 2005-07-28 | 2011-04-26 | American Diagnostica, Inc. | Lupus anticoagulant testing |
| GB0809511D0 (en) * | 2008-05-23 | 2008-07-02 | Guy S And St Thomas S Nhs Foun | Method of testing for antiphospholipid antibodies |
| CN102066947B (zh) * | 2008-06-18 | 2015-10-14 | 积水医疗株式会社 | 凝血时间延长原因的判定方法 |
| JP5537338B2 (ja) * | 2010-08-26 | 2014-07-02 | シスメックス株式会社 | ループスアンチコアグラント検出用試薬キット及びループスアンチコアグラントの存否を判定する方法 |
| JP5903215B2 (ja) * | 2011-02-28 | 2016-04-13 | シスメックス株式会社 | ループスアンチコアグラント検出用試薬キット及びループスアンチコアグラントの存否を判定する方法 |
| KR101979865B1 (ko) * | 2011-06-17 | 2019-05-17 | 학교법인 히가시-니뽄-가쿠엔 | 루프스 안티코아귤란트의 검출방법 |
| WO2016136558A1 (ja) * | 2015-02-27 | 2016-09-01 | 学校法人東日本学園 | 凝固時間の延長原因に関する情報を取得する方法とそれを実施するための装置及びプログラム |
| JP6499488B2 (ja) * | 2015-03-31 | 2019-04-10 | 学校法人東日本学園 | 凝固時間の測定方法、ループスアンチコアグラントの存否の判定方法及びループスアンチコアグラント検出用試薬キット |
| CN106093440A (zh) * | 2016-06-06 | 2016-11-09 | 中国人民解放军总医院 | 一种用于检测人体血液凝集功能的诊断试剂及其制备方法与使用方法 |
| CN107589251B (zh) * | 2017-05-19 | 2020-04-28 | 上海原科实业发展有限公司 | 狼疮抗凝物检测用试剂盒及狼疮抗凝物存在与否判断方法 |
| CN111707837A (zh) * | 2020-05-29 | 2020-09-25 | 上海太阳生物技术有限公司 | 狼疮抗凝物确认试剂盒(凝固法) |
| CN117825681A (zh) * | 2023-12-26 | 2024-04-05 | 米度医疗科技(中山)有限公司 | 一种狼疮抗凝物全液体试剂及其制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4281061A (en) * | 1979-07-27 | 1981-07-28 | Syva Company | Double antibody for enhanced sensitivity in immunoassay |
| US4914040A (en) * | 1988-03-03 | 1990-04-03 | Boehringer Mannheim Gmbh | Reagent and method for determination of a polyvalent substance using an immunoaggregate |
| US5314695A (en) * | 1990-11-13 | 1994-05-24 | Corvas International, Inc. | Tissue factor based prothrombin time reagent |
| US6261792B1 (en) * | 1990-12-07 | 2001-07-17 | The Liposome Company, Inc. | Lipid-dependent diagnostic assays |
| EP0585504A1 (de) * | 1992-09-04 | 1994-03-09 | Pentapharm A.G. | Phospholipidabhängiger Prothrombinaktivator und seine Anwendung in Lupusantikoagulanttesten |
| US5705395A (en) * | 1994-11-14 | 1998-01-06 | The Scripps Research Institute | Method for diagnosis of thrombotic disorders |
| PT947585E (pt) * | 1998-03-19 | 2001-11-30 | Instrumentation Lab Spa | Metodo in vitro melhorado, kits e reagentes para a peaquisa de defeitos de coagulacao sanguinea |
| US6777193B1 (en) * | 2000-08-04 | 2004-08-17 | Escuela Nacional De Ciencias Biologicas, Del Instituto Politecnico Nacional | Methods for diagnostic and/or treatment of antiphospholipids antibodies-related diseases, and devices |
| US20030232075A1 (en) * | 2002-05-06 | 2003-12-18 | University Of Minnesota, A Minnesota Corporation | Compositions for producing factor Xa |
| US20040091952A1 (en) * | 2002-07-25 | 2004-05-13 | Sysmex Corporation | Reagent kit for detecting lupus anticoagulant |
| DE602004016906D1 (de) * | 2003-03-28 | 2008-11-20 | Sysmex Corp | Reagenz zum Nachweis von anti-Phospholipid Antikörper |
| US7932021B2 (en) * | 2005-07-28 | 2011-04-26 | American Diagnostica, Inc. | Lupus anticoagulant testing |
-
2005
- 2005-02-04 DE DE602005006633T patent/DE602005006633D1/de not_active Expired - Lifetime
- 2005-02-04 EP EP05002403A patent/EP1562047B1/de not_active Expired - Lifetime
- 2005-02-04 AT AT05002403T patent/ATE395603T1/de not_active IP Right Cessation
- 2005-02-07 US US11/050,766 patent/US20050175983A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1562047B1 (de) | 2008-05-14 |
| DE602005006633D1 (de) | 2008-06-26 |
| EP1562047A1 (de) | 2005-08-10 |
| US20050175983A1 (en) | 2005-08-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |