ATE511549T1 - Kit zur messung der thrombinerzeugung in einer blut- oder plasmaprobe eines patienten - Google Patents

Kit zur messung der thrombinerzeugung in einer blut- oder plasmaprobe eines patienten

Info

Publication number
ATE511549T1
ATE511549T1 AT05729048T AT05729048T ATE511549T1 AT E511549 T1 ATE511549 T1 AT E511549T1 AT 05729048 T AT05729048 T AT 05729048T AT 05729048 T AT05729048 T AT 05729048T AT E511549 T1 ATE511549 T1 AT E511549T1
Authority
AT
Austria
Prior art keywords
kit
patient
thrombin generation
blood
sample
Prior art date
Application number
AT05729048T
Other languages
English (en)
Inventor
Katalin Varadi
Peter Turecek
Brigitte Keil
Sylvia Peyrer-Heimstaett
Hans-Peter Schwarz
Original Assignee
Baxter Int
Baxter Healthcare Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Int, Baxter Healthcare Sa filed Critical Baxter Int
Application granted granted Critical
Publication of ATE511549T1 publication Critical patent/ATE511549T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745Assays involving non-enzymic blood coagulation factors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT05729048T 2004-03-31 2005-03-30 Kit zur messung der thrombinerzeugung in einer blut- oder plasmaprobe eines patienten ATE511549T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/816,099 US20050221414A1 (en) 2004-03-31 2004-03-31 Kit for measuring the thrombin generation in a sample of a patient's blood or plasma
PCT/EP2005/003328 WO2005095638A2 (en) 2004-03-31 2005-03-30 A kit for measuring the thrombin generation in a sample of a patient’s blood or plasma

Publications (1)

Publication Number Publication Date
ATE511549T1 true ATE511549T1 (de) 2011-06-15

Family

ID=34963198

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05729048T ATE511549T1 (de) 2004-03-31 2005-03-30 Kit zur messung der thrombinerzeugung in einer blut- oder plasmaprobe eines patienten

Country Status (10)

Country Link
US (3) US20050221414A1 (de)
EP (1) EP1730299B1 (de)
JP (1) JP4620726B2 (de)
AT (1) ATE511549T1 (de)
AU (1) AU2005229408B2 (de)
CA (1) CA2558928A1 (de)
ES (1) ES2367439T3 (de)
PL (1) PL1730299T3 (de)
RU (1) RU2360970C2 (de)
WO (1) WO2005095638A2 (de)

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WO2005017486A2 (en) * 2003-06-09 2005-02-24 Mann Kenneth G A global test of the hemostatic system
EP2360269A1 (de) * 2005-07-28 2011-08-24 American Diagnostica Inc. Lupus-Gerinnungshemmerprüfung
US7932021B2 (en) * 2005-07-28 2011-04-26 American Diagnostica, Inc. Lupus anticoagulant testing
US8138308B2 (en) 2005-12-27 2012-03-20 Mcmaster University Modified peptide substrate
US9091700B2 (en) 2005-12-27 2015-07-28 Mcmaster University Modified peptide substrate
FR2978164B1 (fr) * 2011-07-22 2013-08-30 Stago Diagnostica Utilisation d'un substrat dans une methode pour mesurer l'activite des enzymes proteolytiques
FR2978163B1 (fr) * 2011-07-22 2013-08-30 Stago Diagnostica Utilisation d'un substrat dans une methode pour mesurer l'activite des enzymes proteolytiques disponibles
KR101383333B1 (ko) * 2012-01-13 2014-04-10 연세대학교 산학협력단 트롬빈 생성 측정 방법
WO2014098056A1 (ja) * 2012-12-18 2014-06-26 第一三共株式会社 トロンビン産生の測定方法
AU2013203043B2 (en) * 2013-03-15 2016-10-06 Takeda Pharmaceutical Company Limited Methods to produce a human plasma-derived igg preparation enriched in brain disease-related natural iggs
EA028016B1 (ru) * 2013-06-06 2017-09-29 Общество с ограниченной ответственностью "Гематологическая Корпорация" (ООО "ГемаКор") Набор для измерения параметров системы гемостаза в образце крови или ее компонентов
WO2016196207A1 (en) * 2015-05-29 2016-12-08 Water Lens, Llc. Compositions, apparatus, and methods for determining hardness of water and magnesium ion in an analyte composition
JP6626761B2 (ja) 2016-03-30 2019-12-25 シスメックス株式会社 プロトロンビン時間測定用試薬およびその製造方法
EP3455636B1 (de) 2016-05-13 2023-08-23 The Scripps Research Institute Zusammensetzungen und verfahren für antithrombotische und hämostatische therapien
RU177920U1 (ru) * 2016-11-30 2018-03-15 Общество с ограниченной ответственностью "ГемаКор Лабс" (ООО "ГемаКор Лабс") Устройство мониторинга пространственно-временной динамики тромбина
EP3363912B1 (de) * 2017-02-17 2020-10-28 Synapse B.V. Selbstkalibrierter assay zur bestimmung der erzeugung von proteolytischem enzym, dedizierte mittel und verwendungen davon
CN107796793B (zh) * 2017-09-28 2020-04-10 中国科学技术大学 FXa的检测试剂及检测方法
JP7110360B2 (ja) 2017-10-09 2022-08-01 テルモ ビーシーティー バイオテクノロジーズ,エルエルシー 凍結乾燥方法
MX2020007077A (es) 2018-01-04 2020-10-28 Iconic Therapeutics Inc Anticuerpos anti-factor tisular, conjugados anticuerpo-farmaco y metodos relacionados.
CN113597532B (zh) 2019-03-14 2023-02-17 泰尔茂比司特生物技术有限公司 冻干容器填充固定装置、系统及使用方法
CN110208552A (zh) * 2019-05-22 2019-09-06 深圳市国赛生物技术有限公司 凝血酶时间检测试剂及其制备方法
CN110412001B (zh) * 2019-08-01 2022-02-11 武汉塞力斯生物技术有限公司 一种动态监测凝血酶生成能力的试剂盒
WO2022011323A1 (en) * 2020-07-10 2022-01-13 Iconic Therapeutics, Inc. Ocular disease treatment using anti-tissue factor antibodies

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DE3516579A1 (de) * 1984-11-19 1986-05-22 Boehringer Mannheim Gmbh, 6800 Mannheim Gerinnungstest auf teststreifen
US5318899A (en) * 1989-06-16 1994-06-07 Cor Therapeutics, Inc. Platelet aggregation inhibitors
US5314695A (en) 1990-11-13 1994-05-24 Corvas International, Inc. Tissue factor based prothrombin time reagent
ES2115679T3 (es) * 1991-10-04 1998-07-01 Dade Behring Inc Preparacion de reactivos de tiempo de protrombina a partir de factor de tejido humano recombinante y de fosfolipidos sinteticos y naturales purificados.
AT397391B (de) * 1992-05-15 1994-03-25 Immuno Ag Verwendung von prothrombinfragmenten
US6387881B1 (en) * 1992-09-19 2002-05-14 Trigen Ltd Inhibitors and substrates of thrombin
US5418141A (en) * 1994-05-06 1995-05-23 Avocet Medical, Inc. Test articles for performing dry reagent prothrombin time assays
DK0805876T3 (da) * 1995-01-19 2000-11-06 Gen Probe Inc Nukleinsyreamplifikationsoligonukleotider og prober til Lyme-sygdom-associeret Borrelia
US5952198A (en) * 1995-05-04 1999-09-14 Bayer Corporation Production of recombinant Factor VIII in the presence of liposome-like substances of mixed composition
EP0975975A1 (de) * 1997-04-09 2000-02-02 Blutspendedienst der DRK-Landesverbände Nordrhein und Westfalen-Lippe GmbH Verfahren zur bestimmung von aktivierten blutgerinnungsfaktoren in plasma und plasmaderivaten
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Also Published As

Publication number Publication date
RU2360970C2 (ru) 2009-07-10
US20140232029A1 (en) 2014-08-21
EP1730299B1 (de) 2011-06-01
RU2006138237A (ru) 2008-05-10
CA2558928A1 (en) 2005-10-13
PL1730299T3 (pl) 2011-10-31
WO2005095638A3 (en) 2006-03-02
JP2007530963A (ja) 2007-11-01
AU2005229408A1 (en) 2005-10-13
AU2005229408B2 (en) 2009-06-11
JP4620726B2 (ja) 2011-01-26
US8735086B2 (en) 2014-05-27
WO2005095638A2 (en) 2005-10-13
EP1730299A2 (de) 2006-12-13
WO2005095638B1 (en) 2006-11-02
ES2367439T3 (es) 2011-11-03
US20130052672A1 (en) 2013-02-28
US20050221414A1 (en) 2005-10-06

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