|
WO1994003624A1
(en)
*
|
1992-08-04 |
1994-02-17 |
Auerbach Jeffrey I |
Methods for the isothermal amplification of nucleic acid molecules
|
|
US6261808B1
(en)
*
|
1992-08-04 |
2001-07-17 |
Replicon, Inc. |
Amplification of nucleic acid molecules via circular replicons
|
|
US5854033A
(en)
|
1995-11-21 |
1998-12-29 |
Yale University |
Rolling circle replication reporter systems
|
|
US20060166227A1
(en)
*
|
2000-06-20 |
2006-07-27 |
Stephen Kingsmore |
Protein expression profiling
|
|
US6323009B1
(en)
*
|
2000-06-28 |
2001-11-27 |
Molecular Staging, Inc. |
Multiply-primed amplification of nucleic acid sequences
|
|
US6573051B2
(en)
*
|
2001-03-09 |
2003-06-03 |
Molecular Staging, Inc. |
Open circle probes with intramolecular stem structures
|
|
US8137911B2
(en)
*
|
2001-05-22 |
2012-03-20 |
Cellscript, Inc. |
Preparation and use of single-stranded transcription substrates for synthesis of transcription products corresponding to target sequences
|
|
US7297485B2
(en)
*
|
2001-10-15 |
2007-11-20 |
Qiagen Gmbh |
Method for nucleic acid amplification that results in low amplification bias
|
|
US7553619B2
(en)
*
|
2002-02-08 |
2009-06-30 |
Qiagen Gmbh |
Detection method using dissociated rolling circle amplification
|
|
US20040058330A1
(en)
*
|
2002-09-20 |
2004-03-25 |
Prokaria, Ltd. |
Methods of use for thermostable RNA ligases
|
|
AU2003297557B2
(en)
|
2002-11-21 |
2009-02-26 |
Cellscript, Inc. |
Methods for using primers that encode one strand of a double-stranded promoter
|
|
US20040121338A1
(en)
*
|
2002-12-19 |
2004-06-24 |
Alsmadi Osama A. |
Real-time detection of rolling circle amplification products
|
|
US7955795B2
(en)
|
2003-06-06 |
2011-06-07 |
Qiagen Gmbh |
Method of whole genome amplification with reduced artifact production
|
|
US9487823B2
(en)
|
2002-12-20 |
2016-11-08 |
Qiagen Gmbh |
Nucleic acid amplification
|
|
US7192703B2
(en)
*
|
2003-02-14 |
2007-03-20 |
Intel Corporation, Inc. |
Biomolecule analysis by rolling circle amplification and SERS detection
|
|
US20040259128A1
(en)
*
|
2003-03-24 |
2004-12-23 |
Glenn Kawasaki |
Methods and compositions for detecting the presence of target nucleic acids in a sample
|
|
US8043834B2
(en)
*
|
2003-03-31 |
2011-10-25 |
Qiagen Gmbh |
Universal reagents for rolling circle amplification and methods of use
|
|
US20040248103A1
(en)
*
|
2003-06-04 |
2004-12-09 |
Feaver William John |
Proximity-mediated rolling circle amplification
|
|
US7446202B2
(en)
|
2003-12-05 |
2008-11-04 |
Molecular Probes, Inc. |
Cyanine dye compounds
|
|
US7776529B2
(en)
|
2003-12-05 |
2010-08-17 |
Life Technologies Corporation |
Methine-substituted cyanine dye compounds
|
|
GB0422730D0
(en)
*
|
2004-10-13 |
2004-11-17 |
Lingvitae As |
Method
|
|
US20070020644A1
(en)
*
|
2005-01-26 |
2007-01-25 |
Kolykhalov Alexander A |
Method for detection and characterization of short nucleic acids
|
|
WO2006091813A2
(en)
*
|
2005-02-25 |
2006-08-31 |
Stowers Institute For Medical Research |
Novel thermophilic proteins and the nucleic acids encoding them
|
|
EP1863908B1
(de)
|
2005-04-01 |
2010-11-17 |
Qiagen GmbH |
Reverse transkription und amplifikation von rna bei simultaner degradierung von dna
|
|
EP1885718B1
(de)
|
2005-05-11 |
2017-03-15 |
Life Technologies Corporation |
Chemische fluoreszente verbindungen mit hoher selektivität für doppelstrang-dna sowie verfahren zu ihrer verwendung
|
|
US20080293051A1
(en)
*
|
2005-08-30 |
2008-11-27 |
Board Of Regents, The University Of Texas System |
proximity ligation assay
|
|
US20080008997A1
(en)
*
|
2005-08-30 |
2008-01-10 |
Board Of Regents, The University Of Texas System |
Proximity ligation assays with peptide conjugate 'burrs' and aptamers for the sensitive detection of spores and cancer cells
|
|
EP1762627A1
(de)
|
2005-09-09 |
2007-03-14 |
Qiagen GmbH |
Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion
|
|
LT3018206T
(lt)
*
|
2005-12-01 |
2021-12-10 |
Nuevolution A/S |
Fermentiniai kodavimo būdai, skirti didelių bibliotekų efektyviai sintezei
|
|
US8383370B2
(en)
*
|
2007-01-30 |
2013-02-26 |
The Rockefeller University |
Modified RNA ligase for efficient 3′ modification of RNA
|
|
CN101329250B
(zh)
*
|
2007-06-20 |
2011-11-30 |
上海翼和应用生物技术有限公司 |
一种荧光标记探针的pcr-ldr基因多态性检测测序方法
|
|
WO2009056966A1
(en)
*
|
2007-10-31 |
2009-05-07 |
Debiopharm Sa |
Near full-genome assay of hcv drug resistance
|
|
US20100034445A1
(en)
*
|
2008-08-06 |
2010-02-11 |
Genome Corporation |
Continuous imaging of nucleic acids
|
|
US20100032295A1
(en)
*
|
2008-08-06 |
2010-02-11 |
Genome Corporation |
Continuous film electrophoresis
|
|
US20100035325A1
(en)
*
|
2008-08-06 |
2010-02-11 |
Genome Corporation |
Microcapsules and methods of use for amplification and sequencing
|
|
US20100035323A1
(en)
*
|
2008-08-06 |
2010-02-11 |
Genome Corporation |
Methods of using a multiple sheath flow device for the production of microcapsules
|
|
KR101866401B1
(ko)
|
2010-04-05 |
2018-06-11 |
프로그노시스 바이오사이언스, 인코포레이티드 |
공간적으로 엔코딩된 생물학적 검정
|
|
US10787701B2
(en)
|
2010-04-05 |
2020-09-29 |
Prognosys Biosciences, Inc. |
Spatially encoded biological assays
|
|
US20190300945A1
(en)
|
2010-04-05 |
2019-10-03 |
Prognosys Biosciences, Inc. |
Spatially Encoded Biological Assays
|
|
CA2807552A1
(en)
|
2010-08-06 |
2012-02-09 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
CN103228796B
(zh)
*
|
2010-08-11 |
2016-06-01 |
赛路拉公司 |
基因分型dna
|
|
EP2857499A1
(de)
|
2010-10-01 |
2015-04-08 |
Moderna Therapeutics, Inc. |
Manipulierte Nukleinsäuren und Verfahren zur Verwendung davon
|
|
US20120196294A1
(en)
|
2011-01-17 |
2012-08-02 |
Life Technologies Corporation |
Workflow for detection of ligands using nucleic acids
|
|
CA2831613A1
(en)
|
2011-03-31 |
2012-10-04 |
Moderna Therapeutics, Inc. |
Delivery and formulation of engineered nucleic acids
|
|
GB201106254D0
(en)
|
2011-04-13 |
2011-05-25 |
Frisen Jonas |
Method and product
|
|
EP2744916A4
(de)
|
2011-07-13 |
2015-06-17 |
Primeradx Inc |
Multimodale verfahren zur simultanen erkennung und quantifizierung mehrerer nukleinsäuren in einer probe
|
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
EP2570487A1
(de)
|
2011-09-16 |
2013-03-20 |
Lexogen GmbH |
Verfahren zur Nukleinsäuretranskription
|
|
WO2013038010A2
(en)
|
2011-09-16 |
2013-03-21 |
Lexogen Gmbh |
Nucleic acid transcription method
|
|
PT3682905T
(pt)
|
2011-10-03 |
2022-04-07 |
Modernatx Inc |
Nucleósidos, nucleótidos e ácidos nucleicos modificados e respetivas utilizações
|
|
US20130157259A1
(en)
*
|
2011-12-15 |
2013-06-20 |
Samsung Electronics Co., Ltd. |
Method of amplifying dna from rna in sample and use thereof
|
|
ES2923757T3
(es)
|
2011-12-16 |
2022-09-30 |
Modernatx Inc |
Composiciones de ARNm modificado
|
|
EP2794926B1
(de)
*
|
2011-12-22 |
2018-01-17 |
SomaGenics Inc. |
Verfahren zur herstellung kleiner rna-bibliotheken und ihre verwendung zur expressionsprofilierung von ziel-rnas
|
|
WO2013151664A1
(en)
|
2012-04-02 |
2013-10-10 |
modeRNA Therapeutics |
Modified polynucleotides for the production of proteins
|
|
JP6224689B2
(ja)
|
2012-03-15 |
2017-11-01 |
ニユー・イングランド・バイオレイブス・インコーポレイテツド |
シトシンとこれの修飾物とを識別するための、およびメチローム分析のための方法および組成物
|
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
|
US9572897B2
(en)
|
2012-04-02 |
2017-02-21 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
|
US10501512B2
(en)
|
2012-04-02 |
2019-12-10 |
Modernatx, Inc. |
Modified polynucleotides
|
|
US9193994B2
(en)
*
|
2012-04-20 |
2015-11-24 |
Samsung Electronics Co., Ltd. |
Polynucleotide and use thereof
|
|
EP3901280B1
(de)
|
2012-10-17 |
2025-03-12 |
10x Genomics Sweden AB |
Verfahren und produkt zur optimierung einer lokalisierten oder räumlichen detektion einer genexpression in einer gewebeprobe
|
|
PT2922554T
(pt)
|
2012-11-26 |
2022-06-28 |
Modernatx Inc |
Arn modificado nas porções terminais
|
|
US10597650B2
(en)
|
2012-12-21 |
2020-03-24 |
New England Biolabs, Inc. |
Ligase activity
|
|
US10597710B2
(en)
|
2012-12-21 |
2020-03-24 |
New England Biolabs, Inc. |
Ligase activity
|
|
US10114015B2
(en)
|
2013-03-13 |
2018-10-30 |
Meso Scale Technologies, Llc. |
Assay methods
|
|
CN117288934A
(zh)
|
2013-03-13 |
2023-12-26 |
中尺度技术有限责任公司 |
改进的测定方法
|
|
CN105209532B
(zh)
|
2013-03-15 |
2017-11-28 |
路博润先进材料公司 |
不含重金属的cpvc组合物
|
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
|
CN103160594B
(zh)
*
|
2013-04-03 |
2015-03-04 |
中国科学院苏州纳米技术与纳米仿生研究所 |
基于疏水芯片的多重pcr方法
|
|
CN111500680B
(zh)
|
2013-06-25 |
2024-04-16 |
普罗格诺西斯生物科学公司 |
检测样品中生物靶标的空间分布的方法和系统
|
|
CA2923029A1
(en)
|
2013-09-03 |
2015-03-12 |
Moderna Therapeutics, Inc. |
Chimeric polynucleotides
|
|
US10023626B2
(en)
|
2013-09-30 |
2018-07-17 |
Modernatx, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
|
KR20160067219A
(ko)
|
2013-10-03 |
2016-06-13 |
모더나 세라퓨틱스, 인코포레이티드 |
저밀도 지단백질 수용체를 암호화하는 폴리뉴클레오타이드
|
|
KR102757668B1
(ko)
|
2014-05-15 |
2025-01-21 |
메소 스케일 테크놀러지즈, 엘엘시 |
개선된 분석 방법
|
|
WO2016011226A1
(en)
|
2014-07-16 |
2016-01-21 |
Moderna Therapeutics, Inc. |
Chimeric polynucleotides
|
|
CN106661637B
(zh)
|
2014-09-05 |
2021-04-27 |
郑直 |
检测核酸的方法和其应用
|
|
US11091810B2
(en)
*
|
2015-01-27 |
2021-08-17 |
BioSpyder Technologies, Inc. |
Focal gene expression profiling of stained FFPE tissues with spatial correlation to morphology
|
|
US10683534B2
(en)
|
2015-01-27 |
2020-06-16 |
BioSpyder Technologies, Inc. |
Ligation assays in liquid phase
|
|
US9856521B2
(en)
*
|
2015-01-27 |
2018-01-02 |
BioSpyder Technologies, Inc. |
Ligation assays in liquid phase
|
|
US20160108458A1
(en)
*
|
2014-10-06 |
2016-04-21 |
The Board Of Trustees Of The Leland Stanford Junior University |
Multiplexed detection and quantification of nucleic acids in single-cells
|
|
EP4321627A3
(de)
|
2015-04-10 |
2024-04-17 |
10x Genomics Sweden AB |
Räumlich getrennte multiplex-nukleinsäureanalyse von biologischen proben
|
|
WO2016187583A1
(en)
|
2015-05-21 |
2016-11-24 |
Cofactor Genomics, Inc. |
Methods for generating circular dna from circular rna
|
|
US11014957B2
(en)
|
2015-12-21 |
2021-05-25 |
Realseq Biosciences, Inc. |
Methods of library construction for polynucleotide sequencing
|
|
EP4015647B1
(de)
|
2016-02-26 |
2023-08-30 |
The Board of Trustees of the Leland Stanford Junior University |
Multiplexierte einzelmolekül-rna-visualisierung mit einem zwei-sonden-proximitätsligationssystem
|
|
EP3793715A2
(de)
|
2018-05-17 |
2021-03-24 |
Meso Scale Technologies, LLC |
Verfahren zur isolierung von oberflächenmarkerindikatoren
|
|
US11519033B2
(en)
|
2018-08-28 |
2022-12-06 |
10X Genomics, Inc. |
Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample
|
|
US12631624B2
(en)
|
2018-10-23 |
2026-05-19 |
Meso Scale Technologies, Llc. |
Methods for isolating surface marker displaying agents
|
|
EP3894585A2
(de)
|
2018-12-10 |
2021-10-20 |
10X Genomics, Inc. |
Erzeugung von erfassungssonden zur räumlichen analyse
|
|
US12529094B2
(en)
|
2018-12-10 |
2026-01-20 |
10X Genomics, Inc. |
Imaging system hardware
|
|
US11649485B2
(en)
|
2019-01-06 |
2023-05-16 |
10X Genomics, Inc. |
Generating capture probes for spatial analysis
|
|
US11926867B2
(en)
|
2019-01-06 |
2024-03-12 |
10X Genomics, Inc. |
Generating capture probes for spatial analysis
|
|
CN120098057A
(zh)
|
2019-03-01 |
2025-06-06 |
中尺度技术有限责任公司 |
用于免疫方法的被电化学发光标记的探针、使用这类探针的方法和包含这类探针的试剂盒
|
|
EP3976820A1
(de)
|
2019-05-30 |
2022-04-06 |
10X Genomics, Inc. |
Verfahren zum nachweis der räumlichen heterogenität einer biologischen probe
|
|
KR20220100589A
(ko)
|
2019-10-18 |
2022-07-15 |
더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티 |
임상 및 산업 규모의 온전한 조직 시퀀싱
|
|
EP4025711A2
(de)
|
2019-11-08 |
2022-07-13 |
10X Genomics, Inc. |
Erhöhung der spezifität einer analytbindung
|
|
WO2021091611A1
(en)
|
2019-11-08 |
2021-05-14 |
10X Genomics, Inc. |
Spatially-tagged analyte capture agents for analyte multiplexing
|
|
EP4752521A3
(de)
|
2019-12-23 |
2026-08-12 |
10X Genomics, Inc. |
Reversible fixierreagenzien und verfahren zur verwendung davon
|
|
EP4081656A1
(de)
|
2019-12-23 |
2022-11-02 |
10X Genomics, Inc. |
Zusammensetzungen und verfahren zur verwendung von fixierten biologischen proben bei partitionsbasierten tests
|
|
CN121022991A
(zh)
|
2019-12-23 |
2025-11-28 |
10X基因组学有限公司 |
使用rna模板化连接进行空间分析的方法
|
|
US12365942B2
(en)
|
2020-01-13 |
2025-07-22 |
10X Genomics, Inc. |
Methods of decreasing background on a spatial array
|
|
US12405264B2
(en)
|
2020-01-17 |
2025-09-02 |
10X Genomics, Inc. |
Electrophoretic system and method for analyte capture
|
|
US11732299B2
(en)
|
2020-01-21 |
2023-08-22 |
10X Genomics, Inc. |
Spatial assays with perturbed cells
|
|
US11702693B2
(en)
|
2020-01-21 |
2023-07-18 |
10X Genomics, Inc. |
Methods for printing cells and generating arrays of barcoded cells
|
|
US20210230681A1
(en)
|
2020-01-24 |
2021-07-29 |
10X Genomics, Inc. |
Methods for spatial analysis using proximity ligation
|
|
US11821035B1
(en)
|
2020-01-29 |
2023-11-21 |
10X Genomics, Inc. |
Compositions and methods of making gene expression libraries
|
|
US12076701B2
(en)
|
2020-01-31 |
2024-09-03 |
10X Genomics, Inc. |
Capturing oligonucleotides in spatial transcriptomics
|
|
US12110548B2
(en)
|
2020-02-03 |
2024-10-08 |
10X Genomics, Inc. |
Bi-directional in situ analysis
|
|
US11898205B2
(en)
|
2020-02-03 |
2024-02-13 |
10X Genomics, Inc. |
Increasing capture efficiency of spatial assays
|
|
US12110541B2
(en)
|
2020-02-03 |
2024-10-08 |
10X Genomics, Inc. |
Methods for preparing high-resolution spatial arrays
|
|
US11732300B2
(en)
|
2020-02-05 |
2023-08-22 |
10X Genomics, Inc. |
Increasing efficiency of spatial analysis in a biological sample
|
|
US12129516B2
(en)
|
2020-02-07 |
2024-10-29 |
10X Genomics, Inc. |
Quantitative and automated permeabilization performance evaluation for spatial transcriptomics
|
|
US11835462B2
(en)
|
2020-02-11 |
2023-12-05 |
10X Genomics, Inc. |
Methods and compositions for partitioning a biological sample
|
|
US12399123B1
(en)
|
2020-02-14 |
2025-08-26 |
10X Genomics, Inc. |
Spatial targeting of analytes
|
|
US12281357B1
(en)
|
2020-02-14 |
2025-04-22 |
10X Genomics, Inc. |
In situ spatial barcoding
|
|
WO2021167986A1
(en)
|
2020-02-17 |
2021-08-26 |
10X Genomics, Inc. |
In situ analysis of chromatin interaction
|
|
CN116157533A
(zh)
|
2020-02-21 |
2023-05-23 |
10X基因组学有限公司 |
使用杂交方法捕获遗传靶标
|
|
EP4107285B1
(de)
|
2020-02-21 |
2024-10-09 |
10X Genomics, Inc. |
Verfahren und zusammensetzungen für integrierten räumlichen in-situ-test
|
|
US11891654B2
(en)
|
2020-02-24 |
2024-02-06 |
10X Genomics, Inc. |
Methods of making gene expression libraries
|
|
US11926863B1
(en)
|
2020-02-27 |
2024-03-12 |
10X Genomics, Inc. |
Solid state single cell method for analyzing fixed biological cells
|
|
US11768175B1
(en)
|
2020-03-04 |
2023-09-26 |
10X Genomics, Inc. |
Electrophoretic methods for spatial analysis
|
|
US12188085B2
(en)
|
2020-03-05 |
2025-01-07 |
10X Genomics, Inc. |
Three-dimensional spatial transcriptomics with sequencing readout
|
|
US20230125232A1
(en)
*
|
2020-03-31 |
2023-04-27 |
Arcticzymes As |
Atp-dependent dna ligase
|
|
CZ308956B6
(cs)
*
|
2020-04-14 |
2021-10-06 |
Ústav molekulární genetiky AV ČR, v.v.i. |
Způsob detekce RNA se zvýšenou účinností a citlivostí vhodný pro kvantitativní stanovení mRNA a reakční pufr pro použití při tomto způsobu
|
|
EP4139485B1
(de)
|
2020-04-22 |
2023-09-06 |
10X Genomics, Inc. |
Verfahren zur räumlichen analyse unter verwendung von gezieltem rna-abbau
|
|
US20240018571A1
(en)
|
2020-05-19 |
2024-01-18 |
Meso Scale Technologies, Llc. |
Methods, compositions, and kits for nucleic acid detection
|
|
US12416603B2
(en)
|
2020-05-19 |
2025-09-16 |
10X Genomics, Inc. |
Electrophoresis cassettes and instrumentation
|
|
AU2021275906A1
(en)
|
2020-05-22 |
2022-12-22 |
10X Genomics, Inc. |
Spatial analysis to detect sequence variants
|
|
EP4153775B1
(de)
|
2020-05-22 |
2024-07-24 |
10X Genomics, Inc. |
Simultane räumlich-zeitliche messung der genexpression und der zellaktivität
|
|
WO2021242834A1
(en)
|
2020-05-26 |
2021-12-02 |
10X Genomics, Inc. |
Method for resetting an array
|
|
EP4025692A2
(de)
|
2020-06-02 |
2022-07-13 |
10X Genomics, Inc. |
Nukleinsäure-bibliotheksverfahren
|
|
US12265079B1
(en)
|
2020-06-02 |
2025-04-01 |
10X Genomics, Inc. |
Systems and methods for detecting analytes from captured single biological particles
|
|
EP4600376A3
(de)
|
2020-06-02 |
2025-10-22 |
10X Genomics, Inc. |
Räumliche transkriptomik für antigenrezeptoren
|
|
US12031177B1
(en)
|
2020-06-04 |
2024-07-09 |
10X Genomics, Inc. |
Methods of enhancing spatial resolution of transcripts
|
|
EP4421186B1
(de)
|
2020-06-08 |
2025-08-13 |
10X Genomics, Inc. |
Verfahren zur bestimmung eines chirurgischen randes und verfahren zur verwendung davon
|
|
EP4164796A4
(de)
|
2020-06-10 |
2024-03-06 |
10x Genomics, Inc. |
Flüssigkeitsabgabeverfahren
|
|
EP4446430A3
(de)
|
2020-06-10 |
2024-12-18 |
10X Genomics, Inc. |
Verfahren zur bestimmung einer position eines analyten in einer biologischen probe
|
|
US12435363B1
(en)
|
2020-06-10 |
2025-10-07 |
10X Genomics, Inc. |
Materials and methods for spatial transcriptomics
|
|
US12209273B2
(en)
|
2020-06-12 |
2025-01-28 |
10X Genomics, Inc. |
Nucleic acid assays using click chemistry bioconjugation
|
|
EP4450639B1
(de)
|
2020-06-25 |
2025-10-15 |
10X Genomics, Inc. |
Räumliche analyse der dna-methylierung
|
|
US11761038B1
(en)
|
2020-07-06 |
2023-09-19 |
10X Genomics, Inc. |
Methods for identifying a location of an RNA in a biological sample
|
|
US11981960B1
(en)
|
2020-07-06 |
2024-05-14 |
10X Genomics, Inc. |
Spatial analysis utilizing degradable hydrogels
|
|
US12209280B1
(en)
|
2020-07-06 |
2025-01-28 |
10X Genomics, Inc. |
Methods of identifying abundance and location of an analyte in a biological sample using second strand synthesis
|
|
US12553898B1
(en)
|
2020-08-10 |
2026-02-17 |
10X Genomics, Inc. |
Fluorescent hybridization of antibody-oligonucleotide for multiplexing and signal amplification
|
|
US12297499B2
(en)
|
2020-08-17 |
2025-05-13 |
10X Genomics, Inc. |
Multicomponent nucleic acid probes for sample analysis
|
|
US11981958B1
(en)
|
2020-08-20 |
2024-05-14 |
10X Genomics, Inc. |
Methods for spatial analysis using DNA capture
|
|
WO2022051485A2
(en)
|
2020-09-02 |
2022-03-10 |
Meso Scale Technologies,Llc. |
Kits for detecting one or more target analytes in a sample and methods of making and using the same
|
|
US20230349920A1
(en)
|
2020-09-04 |
2023-11-02 |
Meso Scale Technologies, Llc. |
Methods for isolating central nervous system surface marker displaying agents
|
|
CN116194590A
(zh)
|
2020-09-18 |
2023-05-30 |
10X基因组学有限公司 |
样品处理设备和图像配准方法
|
|
US11926822B1
(en)
|
2020-09-23 |
2024-03-12 |
10X Genomics, Inc. |
Three-dimensional spatial analysis
|
|
US12071667B2
(en)
|
2020-11-04 |
2024-08-27 |
10X Genomics, Inc. |
Sequence analysis using meta-stable nucleic acid molecules
|
|
US11827935B1
(en)
|
2020-11-19 |
2023-11-28 |
10X Genomics, Inc. |
Methods for spatial analysis using rolling circle amplification and detection probes
|
|
EP4012046A1
(de)
|
2020-12-11 |
2022-06-15 |
10X Genomics, Inc. |
Verfahren und zusammensetzungen zur multimodalen in-situ-analyse
|
|
WO2022140028A1
(en)
|
2020-12-21 |
2022-06-30 |
10X Genomics, Inc. |
Methods, compositions, and systems for capturing probes and/or barcodes
|
|
CN116848263A
(zh)
|
2020-12-23 |
2023-10-03 |
10X基因组学有限公司 |
用于分析物检测的方法和组合物
|
|
US12060603B2
(en)
|
2021-01-19 |
2024-08-13 |
10X Genomics, Inc. |
Methods for internally controlled in situ assays using padlock probes
|
|
EP4284945B1
(de)
|
2021-01-26 |
2024-10-23 |
10X Genomics, Inc. |
Nukleinsäureanalogsonden zur in-situ-analyse
|
|
ES2989523T3
(es)
|
2021-02-19 |
2024-11-26 |
10X Genomics Inc |
Método de uso de un dispositivo modular de soporte para ensayos
|
|
EP4738279A3
(de)
|
2021-02-19 |
2026-05-13 |
The Broad Institute Inc. |
Multiskalare räumliche transkriptomikanalyse
|
|
US12275984B2
(en)
|
2021-03-02 |
2025-04-15 |
10X Genomics, Inc. |
Sequential hybridization and quenching
|
|
WO2022187366A1
(en)
|
2021-03-03 |
2022-09-09 |
10X Genomics, Inc. |
Analyte detection in situ using nucleic acid origami
|
|
EP4524261B1
(de)
|
2021-03-18 |
2026-07-22 |
10X Genomics, Inc. |
Multiplex-erfassung von gen- und proteinexpression aus einer biologischen probe
|
|
EP4305196B1
(de)
|
2021-04-14 |
2025-04-02 |
10X Genomics, Inc. |
Verfahren zur messung der fehllokalisierung eines analyten
|
|
WO2022221660A1
(en)
|
2021-04-16 |
2022-10-20 |
Meso Scale Technologies, Llc. |
Methods, compositions, and kits for detecting hydrolase enzyme activity
|
|
WO2022231900A1
(en)
|
2021-04-26 |
2022-11-03 |
Meso Scale Technologies, Llc. |
Methods for isolating and analyzing a target analyte encapsulated by a surface marker displaying agent
|
|
EP4320271B1
(de)
|
2021-05-06 |
2025-03-19 |
10X Genomics, Inc. |
Verfahren zur erhöhung der auflösung von räumlicher analyse
|
|
EP4334471A1
(de)
|
2021-05-07 |
2024-03-13 |
The Broad Institute Inc. |
Räumlich-zeitlich aufgelöste transkriptomik bei subzellulärer auflösung
|
|
WO2022241227A1
(en)
|
2021-05-14 |
2022-11-17 |
Akoya Biosciences, Inc. |
Amplification of rna detection signals in biological samples
|
|
CN117396613A
(zh)
|
2021-06-01 |
2024-01-12 |
10X基因组学有限公司 |
用于分析物检测和探针解析的方法和组合物
|
|
US20230084407A1
(en)
|
2021-06-02 |
2023-03-16 |
10X Genomics, Inc. |
Sample analysis using asymmetric circularizable probes
|
|
ES3030033T3
(en)
|
2021-06-03 |
2025-06-26 |
10X Genomics Inc |
Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis
|
|
AU2022304570A1
(en)
|
2021-06-28 |
2024-01-18 |
Meso Scale Technologies, Llc. |
Methods, compositions, and kits for assay signal amplification
|
|
EP4367262A1
(de)
|
2021-07-09 |
2024-05-15 |
10X Genomics, Inc. |
Verfahren zum nachweis von analyten mit spärlicher markierung
|
|
EP4779305A2
(de)
|
2021-07-13 |
2026-07-22 |
10X Genomics, Inc. |
Verfahren zur herstellung einer polymerisierten matrix mit steuerbarer dicke
|
|
US12139751B2
(en)
|
2021-07-30 |
2024-11-12 |
10X Genomics, Inc. |
Circularizable probes for in situ analysis
|
|
EP4326900B1
(de)
|
2021-07-30 |
2024-09-04 |
10X Genomics, Inc. |
Verfahren und zusammensetzungen zur in-situ-synchronisierung von reaktionen
|
|
US12553805B2
(en)
|
2021-08-02 |
2026-02-17 |
10X Genomics, Inc. |
Methods of preserving a biological sample
|
|
US12391984B2
(en)
|
2021-08-03 |
2025-08-19 |
10X Genomics, Inc. |
Compositions and methods for rolling circle amplification
|
|
EP4381095A1
(de)
|
2021-08-03 |
2024-06-12 |
10X Genomics, Inc. |
Nukleinsäurekoncatamere und verfahren zur stabilisierung und/oder verdichtung davon
|
|
US12529096B2
(en)
|
2021-08-03 |
2026-01-20 |
10X Genomics, Inc. |
Stabilization and/or compaction of nucleic acid structures
|
|
US12460251B2
(en)
|
2021-08-03 |
2025-11-04 |
10X Genomics, Inc. |
Stabilization and/or compaction of nucleic acid molecules
|
|
US12435364B2
(en)
|
2021-08-16 |
2025-10-07 |
10X Genomics, Inc. |
Probes comprising a split barcode region and methods of use
|
|
WO2023034489A1
(en)
|
2021-09-01 |
2023-03-09 |
10X Genomics, Inc. |
Methods, compositions, and kits for blocking a capture probe on a spatial array
|
|
EP4419707A1
(de)
|
2021-11-10 |
2024-08-28 |
10X Genomics, Inc. |
Verfahren, zusammensetzungen und kits zur bestimmung der position eines analyten in einer biologischen probe
|
|
EP4305195A2
(de)
|
2021-12-01 |
2024-01-17 |
10X Genomics, Inc. |
Verfahren, zusammensetzungen und systeme für verbesserten in-situ-nachweis von analyten und raumanalyse
|
|
EP4445377A2
(de)
|
2021-12-10 |
2024-10-16 |
10X Genomics, Inc. |
In-situ-decodierung mit mehreren auflösungen
|
|
EP4441711A1
(de)
|
2021-12-20 |
2024-10-09 |
10X Genomics, Inc. |
Selbsttest für eine pathologie-/histologie-objektträgerbildgebungsvorrichtung
|
|
US20230242974A1
(en)
|
2021-12-27 |
2023-08-03 |
10X Genomics, Inc. |
Methods and compositions for rolling circle amplification
|
|
US12674196B2
(en)
|
2022-01-18 |
2026-07-07 |
10X Genomics, Inc. |
Methods and compositions for improved probe specificity
|
|
EP4733410A3
(de)
|
2022-01-21 |
2026-05-27 |
10X Genomics, Inc. |
Mehrere auslesesignale zur analyse einer probe
|
|
US20240254537A1
(en)
|
2022-02-23 |
2024-08-01 |
Insitro, Inc. |
Pooled optical screening and transcriptional measurements of cells comprising barcoded genetic perturbations
|
|
WO2023172915A1
(en)
|
2022-03-08 |
2023-09-14 |
10X Genomics, Inc. |
In situ code design methods for minimizing optical crowding
|
|
US12637706B2
(en)
|
2022-03-23 |
2026-05-26 |
10X Genomics, Inc. |
Methods and compositions related to microsphere surface gelation
|
|
EP4500481A1
(de)
|
2022-03-29 |
2025-02-05 |
10X Genomics, Inc. |
Spektrumsentmischung in kombination mit decodierung für supermultiplexierte in-situ-analyse
|
|
US12687494B2
(en)
|
2022-04-04 |
2026-07-21 |
10X Genomics, Inc. |
Systems and methods for nearly isotropic optical resolution using tilted structured illumination microscopy
|
|
WO2023196526A1
(en)
|
2022-04-06 |
2023-10-12 |
10X Genomics, Inc. |
Methods for multiplex cell analysis
|
|
US20240002902A1
(en)
|
2022-05-06 |
2024-01-04 |
10X Genomics, Inc. |
Analysis of antigen and antigen receptor interactions
|
|
CN119213143A
(zh)
|
2022-05-11 |
2024-12-27 |
10X基因组学有限公司 |
用于原位测序的组合物和方法
|
|
US20240035071A1
(en)
|
2022-06-17 |
2024-02-01 |
10X Genomics, Inc. |
Catalytic de-crosslinking of samples for in situ analysis
|
|
US20240191297A1
(en)
|
2022-10-14 |
2024-06-13 |
10X Genomics, Inc. |
Methods, compositions, and systems for assessing biological sample quality
|
|
EP4685239A1
(de)
|
2022-11-09 |
2026-01-28 |
10X Genomics, Inc. |
Verfahren, zusammensetzungen und kits zur bestimmung der position mehrerer analyten in einer biologischen probe
|
|
US20240158852A1
(en)
|
2022-11-16 |
2024-05-16 |
10X Genomics, Inc. |
Methods and compositions for assessing performance of in situ assays
|
|
US20240218437A1
(en)
|
2022-12-16 |
2024-07-04 |
10X Genomics, Inc. |
Methods and compositions for assessing performance
|
|
WO2024229260A1
(en)
|
2023-05-03 |
2024-11-07 |
10X Genomics, Inc. |
Methods and compositions for spatial assay
|
|
EP4720676A1
(de)
|
2023-05-24 |
2026-04-08 |
Meso Scale Technologies, LLC |
Verfahren zur beurteilung von kolorektalkarzinom mit extrazellulären vesikeln
|
|
WO2025014758A1
(en)
|
2023-07-07 |
2025-01-16 |
10X Genomics, Inc. |
Systems and methods for tissue bounds detection
|
|
WO2025038914A1
(en)
|
2023-08-16 |
2025-02-20 |
10X Genomics, Inc. |
Systems and methods for image segmentation
|
|
WO2025076421A1
(en)
|
2023-10-06 |
2025-04-10 |
10X Genomics, Inc. |
Feature pyramiding for in situ data visualizations
|
|
US20250163502A1
(en)
|
2023-11-22 |
2025-05-22 |
10X Genomics, Inc. |
Methods for processing ribonucleic acids in biological samples
|
|
US20250188524A1
(en)
|
2023-12-07 |
2025-06-12 |
10X Genomics, Inc. |
Graphical user interface and method of estimating an instrument run completion time
|
|
EP4578960A1
(de)
|
2023-12-20 |
2025-07-02 |
10x Genomics, Inc. |
In-situ-detektion von kopienzahlvariationen in biologischen proben
|
|
US12406371B2
(en)
|
2024-01-25 |
2025-09-02 |
10X Genomics, Inc. |
Systems and methods for image segmentation using multiple stain indicators
|
|
WO2025189030A1
(en)
|
2024-03-07 |
2025-09-12 |
Stellaromics, Inc. |
Methods and systems for volumetric imaging
|
|
US20250285229A1
(en)
|
2024-03-08 |
2025-09-11 |
10X Genomics, Inc. |
Multi-focus image fusion with background removal
|
|
WO2025255457A1
(en)
|
2024-06-07 |
2025-12-11 |
10X Genomics, Inc. |
Compositions and methods for improved on-target spatial profiling
|
|
WO2025264702A1
(en)
|
2024-06-18 |
2025-12-26 |
10X Genomics, Inc. |
3d hydrogels for nucleic acid sequencing
|
|
WO2026055487A1
(en)
|
2024-09-06 |
2026-03-12 |
10X Genomics, Inc. |
Modified nucleotides with oligomer spacers
|
|
WO2026076066A1
(en)
|
2024-10-01 |
2026-04-09 |
10X Genomics, Inc. |
Systems and methods for illumination of a sample
|
|
WO2026097020A1
(en)
|
2024-11-04 |
2026-05-07 |
10X Genomics, Inc. |
Polymerase for sequencing by synthesis
|
|
WO2026112273A1
(en)
|
2024-11-20 |
2026-05-28 |
10X Genomics, Inc. |
Assembly for mounting optical filters
|
|
WO2026136874A1
(en)
|
2024-12-20 |
2026-06-25 |
10X Genomics, Inc. |
Systems and methods for image segmentation
|
|
WO2026136945A1
(en)
|
2024-12-20 |
2026-06-25 |
10X Genomics, Inc. |
Methods and compositions for selective control of signal generation efficiency
|
|
WO2026143189A1
(en)
|
2024-12-26 |
2026-07-02 |
10X Genomics, Inc. |
Systems and methods for dynamic volumetric imaging
|
|
WO2026147929A2
(en)
|
2024-12-30 |
2026-07-09 |
10X Genomics, Inc. |
Systems and methods for fluorescence imaging
|
|
WO2026147936A1
(en)
|
2024-12-30 |
2026-07-09 |
10X Genomics, Inc. |
Systems and methods for drift compensation
|
|
WO2026147876A1
(en)
|
2024-12-31 |
2026-07-09 |
10X Genomics, Inc. |
Optical assemblies and methods for optical assembly alignment
|
|
WO2026147822A1
(en)
|
2024-12-31 |
2026-07-09 |
10X Genomics, Inc. |
Systems and methods for autofocus
|
|
WO2026148052A1
(en)
|
2024-12-31 |
2026-07-09 |
10X Genomics, Inc. |
Modified nucleotides with negatively charged spacers
|