ATE403431T1 - Benzimidazolon-verbindungen - Google Patents

Benzimidazolon-verbindungen

Info

Publication number: ATE403431T1
Authority: AT; Austria
Prior art keywords: benzimidazolone compounds; compounds; benzimidazolone; analgetics; formula
Prior art date: 2001-04-18

Application number

AT02764243T

Other languages

English (en)

Inventor

R Goehring

Zhengming Chen

Donald Kyle

Sam Victory

Original Assignee

Euro Celtique Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-04-18

Filing date

2002-04-18

Publication date

2008-08-15

2002-04-18 Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa

2008-08-15 Application granted granted Critical

2008-08-15 Publication of ATE403431T1 publication Critical patent/ATE403431T1/de

Links

150000008641 benzimidazolones Chemical class 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
230000000202 analgesic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Addiction (AREA)
Hematology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Cardiology (AREA)
Obesity (AREA)
Hospice & Palliative Care (AREA)
Rheumatology (AREA)
Child & Adolescent Psychology (AREA)
Urology & Nephrology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Anesthesiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT02764243T 2001-04-18 2002-04-18 Benzimidazolon-verbindungen ATE403431T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US28466501P	2001-04-18	2001-04-18

Publications (1)

Publication Number	Publication Date
ATE403431T1 true ATE403431T1 (de)	2008-08-15

Family

ID=23091051

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT08011371T ATE456564T1 (de)	2001-04-18	2002-04-18	Octahydrobenzimidazolon-verbindungen als analgetika
AT02764243T ATE403431T1 (de)	2001-04-18	2002-04-18	Benzimidazolon-verbindungen

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT08011371T ATE456564T1 (de)	2001-04-18	2002-04-18	Octahydrobenzimidazolon-verbindungen als analgetika

Country Status (13)

Country	Link
US (2)	US6872733B2 (de)
EP (3)	EP1975164B1 (de)
JP (1)	JP4401076B2 (de)
AT (2)	ATE456564T1 (de)
AU (1)	AU2002338424B2 (de)
CA (1)	CA2444489C (de)
CY (2)	CY1108456T1 (de)
DE (2)	DE60228072D1 (de)
DK (2)	DK1385518T3 (de)
ES (2)	ES2312616T3 (de)
PT (2)	PT1975164E (de)
SI (2)	SI1385518T1 (de)
WO (1)	WO2002085361A1 (de)

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PT1491212E (pt)	2002-03-29	2012-11-16	Mitsubishi Tanabe Pharma Corp	Medicamento para distúrbios de sono
US20110008327A1 (en)	2004-03-29	2011-01-13	Cheng Jin Q	Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof
US20100173864A1 (en)	2004-03-29	2010-07-08	Cheng Jin Q	Compositions including triciribine and one or more platinum compounds and methods of use thereof
US20100009929A1 (en)	2004-03-29	2010-01-14	Cheng Jin Q	Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof
CA2561513C (en)	2004-03-29	2019-02-26	University Of South Florida	Effective treatment of tumors and cancer with triciribine and related compounds
US20100028339A1 (en)	2004-03-29	2010-02-04	Cheng Jin Q	Compositions including triciribine and trastuzumab and methods of use thereof
US20100009928A1 (en)	2004-03-29	2010-01-14	Cheng Jin Q	Compositions including triciribine and taxanes and methods of use thereof
EP1943230B1 (de) *	2005-09-30	2010-12-22	Glaxo Group Limited	Verbindungen mit aktivität am m1-rezeptor und ihre verwendung in der medizin
ES2391107T3 (es) *	2005-09-30	2012-11-21	Glaxo Group Limited	Compuestos que tienen actividad en el receptor M1 y sus usos en medicina
EP1937670A1 (de) *	2005-09-30	2008-07-02	Glaxo Group Limited	Benzimidazolone mit aktivität am m1-rezeptor
CN1870631B (zh) *	2005-11-11	2010-04-14	华为技术有限公司	媒体网关的门控方法
TW200813018A (en)	2006-06-09	2008-03-16	Astrazeneca Ab	Novel compounds
US20080051380A1 (en)	2006-08-25	2008-02-28	Auerbach Alan H	Methods and compositions for treating cancer
KR101370434B1 (ko) *	2007-01-16	2014-03-06	시오노기세이야쿠가부시키가이샤	Ｏｒｌ-1 리간드로서의 헤테로시클릭-치환 피페리딘
GB0706188D0 (en) *	2007-03-29	2007-05-09	Glaxo Group Ltd	Compounds
KR20140139125A (ko) *	2007-08-31	2014-12-04	퍼듀 퍼머 엘피	치환-퀴녹살린-형 피페리딘 화합물 및 그의 용도
US8119661B2 (en) *	2007-09-11	2012-02-21	Astrazeneca Ab	Piperidine derivatives and their use as muscarinic receptor modulators
GB0718415D0 (en) *	2007-09-20	2007-10-31	Glaxo Group Ltd	Compounds
HRP20120841T4 (hr)	2008-07-21	2015-07-03	Purdue Pharma L.P.	Premošteni piperidinski spojevi substituiranog kinoksalin-tipa i njihova uporaba
WO2014102594A2 (en)	2012-12-27	2014-07-03	Purdue Pharma L.P.	Substituted benzimidazole-type piperidine compounds and uses thereof
WO2014102590A1 (en)	2012-12-27	2014-07-03	Purdue Pharma L.P.	Substituted piperidin-4-amino-type compounds and uses thereof
WO2014102588A2 (en)	2012-12-27	2014-07-03	Purdue Pharma L.P.	Indole and indoline-type piperidine compounds and uses thereof
WO2014102589A1 (en)	2012-12-27	2014-07-03	Purdue Pharma L.P.	Quinazolin-4(3h)-one-type piperidine compounds and uses thereof
CN119606965A (zh)	2016-07-29	2025-03-14	詹森药业有限公司	治疗前列腺癌的方法

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EP1080091A1 (de)	1998-05-18	2001-03-07	Novo Nordisk A/S	Neue 1,3,8-triazaspiro[4.5]dekanone mit einer hohen affinität für opioid-rezeptor subtypen
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MA26659A1 (fr)	1998-08-06	2004-12-20	Pfizer	Dérivés de benzimidazole nouveaux, compositions pharmaceutiques les contenant et procédé pour leur préparation.
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DE60136546D1 (de)	2000-09-06	2008-12-24	Ortho Mcneil Pharm Inc	Methode zum bekämpfen der allergien durch verwendung von substituierten pyrazolen

2002
- 2002-04-18 PT PT08011371T patent/PT1975164E/pt unknown
- 2002-04-18 US US10/126,437 patent/US6872733B2/en not_active Expired - Lifetime
- 2002-04-18 DE DE60228072T patent/DE60228072D1/de not_active Expired - Lifetime
- 2002-04-18 SI SI200230749T patent/SI1385518T1/sl unknown
- 2002-04-18 ES ES02764243T patent/ES2312616T3/es not_active Expired - Lifetime
- 2002-04-18 DK DK02764243T patent/DK1385518T3/da active
- 2002-04-18 AT AT08011371T patent/ATE456564T1/de not_active IP Right Cessation
- 2002-04-18 JP JP2002582934A patent/JP4401076B2/ja not_active Expired - Fee Related
- 2002-04-18 AU AU2002338424A patent/AU2002338424B2/en not_active Ceased
- 2002-04-18 CA CA2444489A patent/CA2444489C/en not_active Expired - Fee Related
- 2002-04-18 WO PCT/US2002/012375 patent/WO2002085361A1/en not_active Ceased
- 2002-04-18 PT PT02764243T patent/PT1385518E/pt unknown
- 2002-04-18 AT AT02764243T patent/ATE403431T1/de not_active IP Right Cessation
- 2002-04-18 SI SI200230894T patent/SI1975164T1/sl unknown
- 2002-04-18 EP EP08011371A patent/EP1975164B1/de not_active Expired - Lifetime
- 2002-04-18 DE DE60235274T patent/DE60235274D1/de not_active Expired - Lifetime
- 2002-04-18 ES ES08011371T patent/ES2340441T3/es not_active Expired - Lifetime
- 2002-04-18 EP EP02764243A patent/EP1385518B1/de not_active Expired - Lifetime
- 2002-04-18 DK DK08011371.5T patent/DK1975164T3/da active
- 2002-04-18 EP EP10000601A patent/EP2172468A1/de not_active Withdrawn
2005
- 2005-03-28 US US11/091,229 patent/US20050192307A1/en not_active Abandoned
2008
- 2008-10-27 CY CY20081101210T patent/CY1108456T1/el unknown
2010
- 2010-04-14 CY CY20101100336T patent/CY1110000T1/el unknown

Also Published As

Publication number	Publication date
AU2002338424B2 (en)	2005-04-21
PT1385518E (pt)	2008-10-07
US20050192307A1 (en)	2005-09-01
EP1975164B1 (de)	2010-01-27
CY1110000T1 (el)	2012-05-23
SI1975164T1 (sl)	2010-05-31
EP1975164A2 (de)	2008-10-01
JP4401076B2 (ja)	2010-01-20
EP1385518A1 (de)	2004-02-04
DK1975164T3 (da)	2010-05-25
SI1385518T1 (sl)	2009-02-28
CA2444489A1 (en)	2002-10-31
PT1975164E (pt)	2010-04-20
WO2002085361A1 (en)	2002-10-31
CY1108456T1 (el)	2012-05-23
CA2444489C (en)	2010-06-22
EP1975164A3 (de)	2008-10-08
EP1385518A4 (de)	2005-10-05
ES2340441T3 (es)	2010-06-02
US20030008886A1 (en)	2003-01-09
DE60228072D1 (de)	2008-09-18
JP2004531532A (ja)	2004-10-14
EP2172468A1 (de)	2010-04-07
ATE456564T1 (de)	2010-02-15
ES2312616T3 (es)	2009-03-01
DE60235274D1 (de)	2010-03-18
US6872733B2 (en)	2005-03-29
EP1385518B1 (de)	2008-08-06
DK1385518T3 (da)	2008-10-27

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2009-03-15

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2012-01-15

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TH15976A (th)	1995-05-26	อนุพันธ์ของ 1,5-เบนโซไอแอซิพีน