ATE406376T1 - Verfahren zur herstellung von finasterid form i - Google Patents

Verfahren zur herstellung von finasterid form i

Info

Publication number
ATE406376T1
ATE406376T1 AT04743251T AT04743251T ATE406376T1 AT E406376 T1 ATE406376 T1 AT E406376T1 AT 04743251 T AT04743251 T AT 04743251T AT 04743251 T AT04743251 T AT 04743251T AT E406376 T1 ATE406376 T1 AT E406376T1
Authority
AT
Austria
Prior art keywords
finasteride
finasteride form
solvent
producing
producing finasteride
Prior art date
Application number
AT04743251T
Other languages
English (en)
Inventor
Rajendra Kankan
Dharmaraj Rao
Original Assignee
Cipla Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cipla Ltd filed Critical Cipla Ltd
Application granted granted Critical
Publication of ATE406376T1 publication Critical patent/ATE406376T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT04743251T 2003-07-03 2004-07-05 Verfahren zur herstellung von finasterid form i ATE406376T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN676MU2003 2003-07-03

Publications (1)

Publication Number Publication Date
ATE406376T1 true ATE406376T1 (de) 2008-09-15

Family

ID=33561923

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04743251T ATE406376T1 (de) 2003-07-03 2004-07-05 Verfahren zur herstellung von finasterid form i

Country Status (5)

Country Link
US (1) US7550593B2 (de)
EP (1) EP1651661B1 (de)
AT (1) ATE406376T1 (de)
DE (1) DE602004016170D1 (de)
WO (1) WO2005003149A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103169984B (zh) 2006-07-25 2016-08-03 利普生技术有限公司 N末端聚唾液酸化
GB2514958A (en) 2012-02-21 2014-12-10 Sujoy Kumar Guha Drug delivery system for finasteride to prostate
WO2015130963A2 (en) 2014-02-27 2015-09-03 Xenetic Biosciences, Inc. Compositions and methods for administering insulin or insulin-like protein to the brain
US20220023430A1 (en) 2018-11-13 2022-01-27 Lipoxen Technologies Limited Glycopolysialylation of blinatumomab
CN111896658B (zh) * 2020-08-10 2022-10-04 扬子江药业集团四川海蓉药业有限公司 一种利用高效液相色谱仪检测非那雄胺中异构体杂质的方法
CN117886880A (zh) * 2024-01-12 2024-04-16 天方药业有限公司 一种产业化制备非那雄胺过程中提高产品纯度的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4760071A (en) * 1984-02-27 1988-07-26 Merck & Co., Inc. 17β-N-monosubstituted carbamoyl-4-aza-5α-androst-1-en-3-ones which are active as testosterone 5α-reductase inhibitors
US5468860A (en) * 1992-11-19 1995-11-21 Merck & Co., Inc. New finasteride processes
US5547957A (en) * 1993-10-15 1996-08-20 Merck & Co., Inc. Method of treating androgenic alopecia with 5-α reductase inhibitors
US5670643A (en) * 1995-03-16 1997-09-23 Glaxo Wellcome Inc. Method for preparing finasteride
EA200200524A1 (ru) 1999-11-01 2002-10-31 Торкан Кемикал Лтд. Получение полиморфных форм i и ii финастерида путем образования комплексов с солями металлов группы i или ii
CA2422159A1 (en) * 2000-09-07 2002-03-14 Dr. Reddy's Laboratories Ltd. Novel polymorphic form of 17-beta-(n-ter.butyl carbamoyl)-4-aza-5-alpha-androst-1-en-3-one and a process for preparing it
ES2206065B1 (es) 2002-10-31 2005-08-16 Ragactives, S.L. Procedimiento para la obtencion de la forma polimorfica i de finasterida.

Also Published As

Publication number Publication date
WO2005003149A1 (en) 2005-01-13
EP1651661B1 (de) 2008-08-27
US20070021455A1 (en) 2007-01-25
EP1651661A1 (de) 2006-05-03
DE602004016170D1 (de) 2008-10-09
US7550593B2 (en) 2009-06-23

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Legal Events

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