ATE408004T1 - Vögelzell-linien und deren verwendung zur herstellung interessanter biologischer substanzen - Google Patents
Vögelzell-linien und deren verwendung zur herstellung interessanter biologischer substanzenInfo
- Publication number
- ATE408004T1 ATE408004T1 AT03725273T AT03725273T ATE408004T1 AT E408004 T1 ATE408004 T1 AT E408004T1 AT 03725273 T AT03725273 T AT 03725273T AT 03725273 T AT03725273 T AT 03725273T AT E408004 T1 ATE408004 T1 AT E408004T1
- Authority
- AT
- Austria
- Prior art keywords
- cell lines
- serum
- growth factors
- medium
- feeder layer
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
- C12N2500/92—Medium free of human- or animal-derived components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
- C12N2500/95—Protein-free medium and culture conditions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Chemical & Material Sciences (AREA)
- Gynecology & Obstetrics (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Reproductive Health (AREA)
- Developmental Biology & Embryology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Farming Of Fish And Shellfish (AREA)
- Peptides Or Proteins (AREA)
- Feeding And Watering For Cattle Raising And Animal Husbandry (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0202945A FR2836924B1 (fr) | 2002-03-08 | 2002-03-08 | Lignees de cellules aviaires utiles pour la production de substances d'interet |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE408004T1 true ATE408004T1 (de) | 2008-09-15 |
Family
ID=27763651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03725273T ATE408004T1 (de) | 2002-03-08 | 2003-03-07 | Vögelzell-linien und deren verwendung zur herstellung interessanter biologischer substanzen |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US20040058441A1 (de) |
| EP (2) | EP1992687B1 (de) |
| JP (2) | JP5025888B2 (de) |
| CN (2) | CN101676388B (de) |
| AT (1) | ATE408004T1 (de) |
| AU (1) | AU2003227820B2 (de) |
| CA (1) | CA2478125C (de) |
| DE (1) | DE60323468D1 (de) |
| DK (1) | DK1483369T3 (de) |
| ES (1) | ES2312775T3 (de) |
| FR (1) | FR2836924B1 (de) |
| PT (1) | PT1483369E (de) |
| SI (1) | SI1483369T1 (de) |
| WO (1) | WO2003076601A1 (de) |
Families Citing this family (120)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7445924B2 (en) * | 2000-11-23 | 2008-11-04 | Bavarian Nordic A/S | Modified Vaccinia Ankara virus variant and cultivation method |
| US7145057B2 (en) | 2002-02-01 | 2006-12-05 | Origen Therapeutics, Inc. | Chimeric bird from embryonic stem cells |
| US20060191026A1 (en) | 2005-02-18 | 2006-08-24 | Origen Therapeutics, Inc. | Tissue specific expression of antibodies in chickens |
| FR2836924B1 (fr) | 2002-03-08 | 2005-01-14 | Vivalis | Lignees de cellules aviaires utiles pour la production de substances d'interet |
| UA85543C2 (ru) | 2002-09-05 | 2009-02-10 | Бавариан Нордик А/С | Способ культивирования первичных клеток и амплификации вирусов в условиях безсывороточной среды, композиция и ее применение, и способ лечения или вакцинации животных |
| CN1726276A (zh) * | 2002-12-13 | 2006-01-25 | 艾文蒂斯·帕斯图尔公司 | Alvac在禽胚胎干细胞上的生产 |
| CA2531565C (en) | 2003-07-22 | 2014-02-11 | Vivalis | Production of poxviruses with adherent or non adherent avian cell lines |
| EP1500699A1 (de) * | 2003-07-22 | 2005-01-26 | Vivalis | Herstellung von Vacciniaviren mit Hilfe adhärenter oder nicht adhärenter Vogelzelllinien |
| EP1678292A4 (de) * | 2003-09-18 | 2008-05-07 | Univ Emory | Verbesserte mva-impfstoffe |
| JP4896021B2 (ja) | 2004-05-21 | 2012-03-14 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス, インコーポレイテッド | 呼吸器系病原体ワクチンのためのアルファウイルスベクター |
| PL2236155T3 (pl) | 2004-09-09 | 2012-10-31 | Novartis Ag | Zmniejszenie potencjalnego zagrożenia jatrogennego związanego ze szczepionkami przeciwko grypie |
| EP2923711A1 (de) | 2004-11-03 | 2015-09-30 | Novartis Vaccines and Diagnostics, Inc. | Grippeimpfung |
| FR2878860A1 (fr) * | 2004-12-08 | 2006-06-09 | Vivalis Sa | Lignees de cellules souches humaines derivees de cellules es et utilisations pour la production de vaccins et de proteines recombinantes |
| AU2011253998B2 (en) * | 2005-04-11 | 2014-04-24 | Valneva | Process of manufacturing viral vaccines in suspension avian embryonic derived stem cell lines |
| FR2884255B1 (fr) * | 2005-04-11 | 2010-11-05 | Vivalis | Utilisation de lignees de cellules souches aviaires ebx pour la production de vaccin contre la grippe |
| ES2359214T5 (es) | 2005-11-01 | 2014-10-08 | Novartis Vaccines And Diagnostics Gmbh | Vacunas virales derivadas de células con niveles reducidos de ADN celular residual por tratamiento con beta-propiolactona |
| PL1945252T3 (pl) | 2005-11-04 | 2013-11-29 | Seqirus Uk Ltd | Szczepionki zawierające oczyszczone antygeny powierzchniowe otrzymane z wirusów grypy hodowanych w hodowli komórkowej i skwalen jako adiuwant |
| BRPI0618254A2 (pt) | 2005-11-04 | 2011-08-23 | Novartis Vaccines & Diagnostic | emulsões com agente tensoativo de fase aquosa livre para fornecer adjuvante às vacinas contra influenza dividido |
| CN102755645A (zh) | 2005-11-04 | 2012-10-31 | 诺华疫苗和诊断有限公司 | 佐剂配制的包含细胞因子诱导剂的流感疫苗 |
| PL1951299T3 (pl) | 2005-11-04 | 2012-07-31 | Novartis Ag | Szczepionki przeciw grypie zawierające kombinacje adiuwantów cząsteczkowych i czynników wzmacniających immunogenność |
| US20090304742A1 (en) | 2005-11-04 | 2009-12-10 | Novartis Vaccines And Diagnostics Srl | Influenza vaccines with reduced amount of emulsion adjuvant |
| KR20080089663A (ko) | 2006-01-27 | 2008-10-07 | 노바티스 백신즈 앤드 다이아그노스틱스 게엠베하 운트 콤파니 카게 | 적혈구응집소 및 기질 단백질을 함유한 인플루엔자 백신 |
| FR2898909A1 (fr) | 2006-03-24 | 2007-09-28 | Agronomique Inst Nat Rech | Combinaison de marqueurs de cellules aviaires |
| JP2009534303A (ja) | 2006-03-24 | 2009-09-24 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス ゲーエムベーハー アンド カンパニー カーゲー | 冷蔵しないインフルエンザワクチンの保存 |
| GB0614460D0 (en) | 2006-07-20 | 2006-08-30 | Novartis Ag | Vaccines |
| MX2009001477A (es) | 2006-08-09 | 2009-02-18 | Vivalis | Metodo de produccion de un aviar transgenico utilizando celulas progenitoras embrionicas. |
| WO2008032219A2 (en) | 2006-09-11 | 2008-03-20 | Novartis Ag | Making influenza virus vaccines without using eggs |
| CN101553252A (zh) | 2006-12-06 | 2009-10-07 | 诺华有限公司 | 包含来自于四株流感病毒的抗原的疫苗 |
| CN100443588C (zh) * | 2006-12-11 | 2008-12-17 | 中国农业科学院北京畜牧兽医研究所 | 静宁鸡胚成纤维细胞系及其培养方法 |
| EP1985305A1 (de) * | 2007-04-24 | 2008-10-29 | Vivalis | Aus Entenembryonen gewonnene Stammzellkulturen zur Herstellung von Impfstoffen gegen Viren |
| EP1995309A1 (de) * | 2007-05-21 | 2008-11-26 | Vivalis | Rekombinante Proteinproduktion in EBx -Vogelzellen |
| HRP20120790T1 (hr) | 2007-06-27 | 2013-01-31 | Novartis Ag | Cjepiva protiv influence sa niskom koliäśinom aditiva |
| ES2618490T3 (es) * | 2007-07-03 | 2017-06-21 | Transgene Sa | Estirpes celulares aviares inmortalizadas |
| US20090028831A1 (en) * | 2007-07-23 | 2009-01-29 | University Of Kentucky Research Foundation | Stem cell regulator, compositions and methods of use |
| GB0810305D0 (en) | 2008-06-05 | 2008-07-09 | Novartis Ag | Influenza vaccination |
| WO2009081172A1 (en) | 2007-12-24 | 2009-07-02 | Novartis Ag | Assays for adsorbed influenza vaccines |
| US8506966B2 (en) | 2008-02-22 | 2013-08-13 | Novartis Ag | Adjuvanted influenza vaccines for pediatric use |
| KR101445433B1 (ko) | 2008-02-25 | 2014-09-26 | 백스터 인터내셔널 인코포레이티드 | 연속 세포주 제조 방법 |
| ES2535101T3 (es) | 2008-03-18 | 2015-05-05 | Novartis Ag | Mejoras en la preparación de antígenos en vacuna de virus de la gripe |
| WO2009132195A1 (en) * | 2008-04-23 | 2009-10-29 | Michigan State University | Immortal avian cell line and methods of use |
| US9181341B2 (en) | 2009-01-19 | 2015-11-10 | Innate Pharma | Anti-KIR3D antibodies |
| EP2396032B1 (de) | 2009-02-10 | 2016-09-28 | Seqirus UK Limited | Influenza-impfstoffe mit reduzierten squalen-mengen |
| WO2010092477A1 (en) | 2009-02-10 | 2010-08-19 | Novartis Ag | Influenza vaccines with increased amounts of h3 antigen |
| WO2010092476A1 (en) | 2009-02-10 | 2010-08-19 | Novartis Ag | Influenza vaccine regimens for pandemic-associated strains |
| CA2763816A1 (en) | 2009-04-27 | 2010-11-04 | Novartis Ag | Adjuvanted vaccines for protecting against influenza |
| PL3178490T3 (pl) | 2009-07-15 | 2022-08-01 | Glaxosmithkline Biologicals S.A. | Kompozycje białka f rsv i sposoby ich wytwarzania |
| CA2773637A1 (en) | 2009-09-10 | 2011-03-17 | Novartis Ag | Combination vaccines against respiratory tract diseases |
| GB0918830D0 (en) | 2009-10-27 | 2009-12-09 | Glaxosmithkline Biolog Niederl | Process |
| GB0919117D0 (en) * | 2009-10-30 | 2009-12-16 | Glaxosmithkline Biolog Sa | Process |
| CA3177833A1 (en) | 2009-12-15 | 2011-06-15 | University Of Saskatchewan | Vaccines for inclusion body hepatitis |
| US20120309056A1 (en) | 2010-02-04 | 2012-12-06 | Leon Arnaud | Fed-batch process using concentrated cell culture medium for the efficient production of biologics in eb66 cells |
| FR2956409A1 (fr) | 2010-02-15 | 2011-08-19 | Univ Claude Bernard Lyon | Procedes pour optimiser la production virale par l'inactivation ou l'inhibition du gene hipk2 et cellules modifiees pour la production virale |
| JP2013521771A (ja) | 2010-03-08 | 2013-06-13 | ノバルティス アーゲー | 細胞内病原体について試験する方法 |
| EP2556151A1 (de) | 2010-04-07 | 2013-02-13 | Novartis AG | Verfahren zur erzeugung von virusähnlichen parvovirus-b19-partikeln |
| US9441032B2 (en) | 2010-04-07 | 2016-09-13 | Agency For Science, Technology And Research | Binding molecules against Chikungunya virus and uses thereof |
| EP2374816B1 (de) | 2010-04-07 | 2016-09-28 | Agency For Science, Technology And Research | Bindemoleküle gegen Chikungunya-Virus und Verwendungen davon |
| BR112012028146A2 (pt) | 2010-05-06 | 2015-09-15 | Novartis Ag | compostos de peróxido orgânico para inativação de microorganismos |
| JP5876036B2 (ja) | 2010-05-21 | 2016-03-02 | ノバルティス アーゲー | インフルエンザウイルス再集合方法 |
| DK2575872T3 (da) | 2010-06-01 | 2020-10-19 | Seqirus Uk Ltd | Koncentrering af influenzavaccineantigener uden frysetørring |
| US20130243841A1 (en) | 2010-06-01 | 2013-09-19 | Novartis Ag | Concentration of vaccine antigens with lyophilization |
| CN103154242B (zh) | 2010-07-06 | 2015-09-30 | 诺华股份有限公司 | 诺如病毒衍生的免疫原性组合物和方法 |
| GB201011502D0 (en) | 2010-07-08 | 2010-08-25 | Glaxosmithkline Biolog Sa | Novel process |
| US9517205B2 (en) | 2010-08-20 | 2016-12-13 | Seqirus UK Limited | Soluble needle arrays for delivery of influenza vaccines |
| US10214722B2 (en) | 2010-09-07 | 2019-02-26 | Technion Research & Development Foundation Limited | Methods for expanding and maintaining human pluripotent stem cells (PSCs) in an undifferentiated state in a single cell suspension culture |
| FR2967072B1 (fr) | 2010-11-05 | 2013-03-29 | Univ Dundee | Procede pour ameliorer la production de virus et semences vaccinales influenza |
| WO2012095514A1 (en) | 2011-01-14 | 2012-07-19 | Vivalis | Recombinant protein production system |
| PL2667892T3 (pl) | 2011-01-26 | 2019-09-30 | Glaxosmithkline Biologicals Sa | Schemat szczepień przeciwko rsv |
| ES2651143T3 (es) | 2011-05-13 | 2018-01-24 | Glaxosmithkline Biologicals Sa | Antígenos de F de prefusión del VRS |
| EP3508219A1 (de) | 2011-07-06 | 2019-07-10 | GlaxoSmithKline Biologicals S.A. | Selbst-replizierende rna-prime - protein boost impfstoffe |
| EP3854413A1 (de) | 2011-07-06 | 2021-07-28 | GlaxoSmithKline Biologicals SA | Immunogene kombinationszusammensetzungen und ihre verwendung |
| TWI575070B (zh) | 2011-07-12 | 2017-03-21 | 傳斯堅公司 | Hbv聚合酶突變體 |
| TW201318637A (zh) | 2011-09-29 | 2013-05-16 | Transgene Sa | 免疫療法組成物及用於治療c型肝炎病毒感染之療程(一) |
| TW201321016A (zh) | 2011-09-29 | 2013-06-01 | Transgene Sa | 免疫療法組成物及用於治療c型肝炎病毒感染之療程(二) |
| US20140348863A1 (en) | 2011-10-12 | 2014-11-27 | Alessia Bianchi | Cmv antigens and uses thereof |
| GB201216121D0 (en) | 2012-09-10 | 2012-10-24 | Novartis Ag | Sample quantification by disc centrifugation |
| EP2768528A1 (de) | 2011-10-20 | 2014-08-27 | Novartis AG | Adjuvierte influenza-b-viren-impfstoffe für kinder |
| EP2660316A1 (de) | 2012-05-02 | 2013-11-06 | Helmholtz-Zentrum für Infektionsforschung GmbH | Vogelzelllinie und deren Verwendung bei der Herstellung eines Proteins |
| CN104853770A (zh) | 2012-07-06 | 2015-08-19 | 诺华股份有限公司 | 免疫原性组合物及其应用 |
| CA2878800A1 (en) | 2012-07-10 | 2014-01-16 | Transgene Sa | Mycobacterial antigen vaccine |
| WO2014009433A1 (en) | 2012-07-10 | 2014-01-16 | Transgene Sa | Mycobacterium resuscitation promoting factor for use as adjuvant |
| GB201218195D0 (en) | 2012-10-10 | 2012-11-21 | Istituto Zooprofilattico Sperimentale Delle Venezie | Composition |
| EP2922570A1 (de) | 2012-11-20 | 2015-09-30 | GlaxoSmithKline Biologicals SA | Präfusionierte rsv-f-trimere |
| US20140255447A1 (en) * | 2013-03-05 | 2014-09-11 | Biomune Company | Production of avian embryo cells |
| FR3008992A1 (fr) * | 2013-07-25 | 2015-01-30 | Agronomique Inst Nat Rech | Procede de selection d'une lignee cellulaire permissive pour la replication de virus aviaires |
| RU2695462C2 (ru) | 2014-01-09 | 2019-07-23 | Трансген Са | Гибридизация гетероолигомерных микобактериальных антигенов |
| EP2974739A1 (de) | 2014-07-15 | 2016-01-20 | Novartis AG | RSVF-Trimerisierungsdomänen |
| EP3031822A1 (de) | 2014-12-08 | 2016-06-15 | Novartis AG | Cytomegalovirus-Antigene |
| US11118238B2 (en) | 2014-12-17 | 2021-09-14 | Fundación Para La Investigación Mèdica Aplicada | Nucleic acid constructs and gene therapy vectors for use in the treatment of Wilson's disease and other conditions |
| RU2745567C2 (ru) | 2014-12-17 | 2021-03-29 | Фундасион Пара Ла Инвестигасион Медика Апликада | Конструкции нуклеиновой кислоты и векторы для генотерапии для применения для лечения болезни вильсона и других состояний |
| EP3047856A1 (de) | 2015-01-23 | 2016-07-27 | Novartis AG | Cmv-antigene und ihre verwendungen |
| AU2016281904B2 (en) | 2015-06-26 | 2022-08-11 | Seqirus UK Limited | Antigenically matched influenza vaccines |
| WO2017005880A1 (en) | 2015-07-07 | 2017-01-12 | Seqirus UK Limited | Influenza potency assays |
| CN110506060B (zh) | 2017-03-30 | 2024-05-07 | 昆士兰大学 | 嵌合分子及其用途 |
| EP3687561A4 (de) | 2017-09-01 | 2021-06-09 | The Australian National University | Immunregulatorische moleküle und deren verwendung |
| SG11202004926WA (en) | 2017-12-01 | 2020-06-29 | Encoded Therapeutics Inc | Engineered dna binding proteins |
| US20210180084A1 (en) | 2018-05-14 | 2021-06-17 | Vivet Therapeutics | Gene therapy vectors comprising s/mar sequences |
| CN112384627A (zh) | 2018-05-30 | 2021-02-19 | 生物医学研究所 | 通过利用内源激活诱导性胞嘧啶脱氨酶改造b淋巴细胞 |
| WO2020012037A1 (en) | 2018-07-13 | 2020-01-16 | Valneva Se | Method for rescuing and producing a virus in avian cells |
| BR112021006881A2 (pt) | 2018-10-12 | 2021-07-13 | Vivet Therapeutics | transgene otimizado por códon para o tratamento de colestase intra-hepática familiar progressiva tipo 3 (pfic3) |
| SG11202104634UA (en) | 2018-11-07 | 2021-06-29 | Vivet Therapeutics | Codon-optimized abcb11 transgene for the treatment of progressive familial intrahepatic cholestasis type 2 (pfic2) |
| WO2020102723A1 (en) | 2018-11-16 | 2020-05-22 | Encoded Therapeutics, Inc. | Compositions and methods for treating wilson's disease |
| EP3884039A1 (de) | 2018-11-23 | 2021-09-29 | Valneva SE | Nahrungsmittel mit aviären stammzellen |
| AU2020279080B2 (en) | 2019-05-22 | 2025-11-27 | Hadasit Medical Research Services And Development Ltd. | Methods of culturing human pluripotent cells |
| BR112021024055A2 (pt) | 2019-05-29 | 2022-02-08 | Encoded Therapeutics Inc | Composições e métodos para a regulação seletiva de gene |
| WO2021001377A1 (en) | 2019-07-02 | 2021-01-07 | Fundacion Para La Investigacion Medica Aplicada | cPLA2e INDUCING AGENTS AND USES THEREOF |
| AU2020318680B2 (en) | 2019-07-21 | 2025-04-24 | Glaxosmithkline Biologicals Sa | Therapeutic viral vaccine |
| EP4004018A1 (de) | 2019-07-24 | 2022-06-01 | GlaxoSmithKline Biologicals SA | Modifizierte humane cytomegalovirus-proteine |
| BR112022004333A2 (pt) * | 2019-09-10 | 2022-05-31 | Vital Meat | Produtos alimentícios, método para preparar os referidos produtos e uso de células-tronco aviárias para a fabricação dos mesmos |
| US12576146B2 (en) | 2019-11-18 | 2026-03-17 | Seqirus UK Limited | Method for producing reassortant influenza viruses |
| CA3181024A1 (en) | 2020-08-06 | 2022-02-10 | Fundacion Para La Investigacion Medica Aplicada | Viral particles for use in treating tauopathies such as alzheimer's diseases by gene therapy |
| US20230265456A1 (en) | 2020-08-10 | 2023-08-24 | Fundacion Para La Investigacion Medica Aplicada | Gene therapy vector expressing cyp27a1 for the treatment of cerebrotendinous xanthomatosis |
| CN116390935A (zh) | 2020-10-09 | 2023-07-04 | Ucb生物制药有限责任公司 | 核酸构建体、病毒载体和病毒颗粒 |
| EP4267197A1 (de) | 2020-12-23 | 2023-11-01 | Vivet Therapeutics | Durch minimale gallensäure induzierbare promotoren zur gentherapie |
| EP4032547A1 (de) | 2021-01-20 | 2022-07-27 | GlaxoSmithKline Biologicals S.A. | Hsv1 fce abgeleitete fragemente zur hsv therapie |
| MX2024005171A (es) | 2021-10-28 | 2024-05-13 | UCB Biopharma SRL | Constructos de acido nucleico, vectores viricos y particulas viricas. |
| WO2023144665A1 (en) | 2022-01-28 | 2023-08-03 | Glaxosmithkline Biologicals Sa | Modified human cytomegalovirus proteins |
| CN114480286B (zh) * | 2022-02-16 | 2024-05-31 | 上海健士拜生物科技有限公司 | 无血清悬浮型lmh细胞系及其制备方法和应用 |
| CN116656628A (zh) * | 2023-07-31 | 2023-08-29 | 深圳市卫光生物制品股份有限公司 | 一种痘病毒载体疫苗的制备方法 |
| EP4567102A1 (de) | 2023-12-05 | 2025-06-11 | Suprême | Verfahren zur isolierung embryonaler stammzellen aus embryonalen vogelzellen |
| CN118956737A (zh) * | 2024-07-17 | 2024-11-15 | 广州沃亘生物科技有限公司 | 一种长期维持df-1细胞活力的培养基及其用途 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4388298A (en) | 1982-07-14 | 1983-06-14 | The United States Of America As Represented By The Secretary Of Agriculture | Propagation of hemorrhagic enteritis virus in a turkey cell line and vaccine produced |
| JP2740320B2 (ja) | 1988-08-04 | 1998-04-15 | アムラド・コーポレイション・リミテッド | 胚幹細胞のインビトロ増殖 |
| US5162215A (en) * | 1988-09-22 | 1992-11-10 | Amgen Inc. | Method of gene transfer into chickens and other avian species |
| US5388680A (en) | 1990-10-09 | 1995-02-14 | Intellicall, Inc. | Coin handling system with an improved coin chute |
| ES2137190T3 (es) | 1991-07-12 | 1999-12-16 | Pfizer | Linea de celulas continua y vacuna contra los coccidios aviarios. |
| JPH05227947A (ja) | 1992-01-14 | 1993-09-07 | Rikagaku Kenkyusho | 鳥類原始生殖細胞の分離方法 |
| WO1993015185A1 (en) | 1992-01-27 | 1993-08-05 | North Carolina State University | GENE TRANSFER IN POULTRY BY INTRODUCTION OF EMBRYO CELLS $i(IN OVO) |
| US5340740A (en) * | 1992-05-15 | 1994-08-23 | North Carolina State University | Method of producing an avian embryonic stem cell culture and the avian embryonic stem cell culture produced by the process |
| WO1994003585A1 (en) | 1992-08-04 | 1994-02-17 | Commonwealth Scientific And Industrial Research Organisation | A method for maintaining embryonic stem cells and avian factor useful for same |
| US5453357A (en) * | 1992-10-08 | 1995-09-26 | Vanderbilt University | Pluripotential embryonic stem cells and methods of making same |
| US5589458A (en) * | 1992-11-13 | 1996-12-31 | Thomas Jefferson University | Compounds that inhibit T cell proliferation and methods for using the same |
| FR2726003B1 (fr) * | 1994-10-21 | 2002-10-18 | Agronomique Inst Nat Rech | Milieu de culture de cellules embryonnaires totipotentes aviaires, procede de culture de ces cellules, et cellules embryonnaires totipotentes aviaires |
| US5989805A (en) | 1995-10-27 | 1999-11-23 | Board Of Trustees Operating Michigan State University | Immortal avian cell line to grow avian and animal viruses to produce vaccines |
| FR2749022B1 (fr) | 1996-05-23 | 2001-06-01 | Rhone Merieux | Cellules aviaires immortelles |
| US5691200A (en) | 1996-07-03 | 1997-11-25 | The United States Of America As Represented By The Secretary Of Agriculture | Method to produce granulocyte colony stimulating factor from immortalized avian T lymphocytes and method to produce immortalized cells |
| US5672485A (en) | 1996-08-13 | 1997-09-30 | Regents Of The University Of Minnesota | Immortalized cell lines for virus growth |
| US5830723A (en) | 1996-08-13 | 1998-11-03 | Regents Of The University Of Minnesota | Method for immortalizing chicken cells |
| EP1983044B1 (de) | 1996-10-10 | 2016-08-10 | Life Technologies Corporation | Tierzellkulturmedien mit Nährstoffen aus Pflanzen |
| EP0841392B1 (de) | 1996-11-12 | 2004-07-14 | Pfizer Inc. | Attenuierter lebender Neospora Impfstoff |
| BR9811830A (pt) * | 1997-08-04 | 2000-08-15 | Univ Massachusetts | Processo de cultivo que proporciona manutenção de células germinais primitivas de ave por perìodos prolongados, processo de produção de aves quiméricas, e, linhagem celular de pgc de ave |
| CA2300336A1 (en) * | 1997-08-04 | 1999-02-11 | University Of Massachusetts A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus | Production of avian embryonic germ (eg) cell lines by prolonged culturing of pgcs, use thereof for cloning and chimerization |
| US6406909B1 (en) | 1998-07-10 | 2002-06-18 | Chugai Seiyaku Kabushiki Kaisha | Serum-free medium for culturing animal cells |
| WO2000047717A1 (en) * | 1999-02-11 | 2000-08-17 | Hanmi Pharm. Co., Ltd. | Avian pluripotent embryonic germ cell line |
| JP4972261B2 (ja) * | 1999-08-27 | 2012-07-11 | ライフ テクノロジーズ コーポレーション | 金属結合化合物および細胞培養培地組成物中でのそれらの使用 |
| DE19947407C2 (de) | 1999-10-01 | 2002-08-01 | Bayerische Motoren Werke Ag | Datenbussystem für Kraftfahrzeuge |
| US20030036195A1 (en) * | 2001-04-20 | 2003-02-20 | Lorenz Studer | Generation of differentiated tissue from nuclear transfer embryonic stem cells and methods of use |
| FR2836924B1 (fr) | 2002-03-08 | 2005-01-14 | Vivalis | Lignees de cellules aviaires utiles pour la production de substances d'interet |
| JP2005532057A (ja) | 2002-07-09 | 2005-10-27 | バクスター・インターナショナル・インコーポレイテッド | 細胞を培養するための動物性タンパク質非含有培地 |
| CA2531565C (en) | 2003-07-22 | 2014-02-11 | Vivalis | Production of poxviruses with adherent or non adherent avian cell lines |
| EP1500699A1 (de) | 2003-07-22 | 2005-01-26 | Vivalis | Herstellung von Vacciniaviren mit Hilfe adhärenter oder nicht adhärenter Vogelzelllinien |
| KR100552844B1 (ko) * | 2003-12-31 | 2006-02-21 | 동부아남반도체 주식회사 | 반도체 소자의 제조 방법 |
| FR2884255B1 (fr) | 2005-04-11 | 2010-11-05 | Vivalis | Utilisation de lignees de cellules souches aviaires ebx pour la production de vaccin contre la grippe |
| WO2007135133A1 (en) | 2006-05-19 | 2007-11-29 | Vivalis | Avian cell lines derived from primordial germ cells useful for the production of substances of interest |
| MX2009001477A (es) | 2006-08-09 | 2009-02-18 | Vivalis | Metodo de produccion de un aviar transgenico utilizando celulas progenitoras embrionicas. |
| EP1985305A1 (de) | 2007-04-24 | 2008-10-29 | Vivalis | Aus Entenembryonen gewonnene Stammzellkulturen zur Herstellung von Impfstoffen gegen Viren |
-
2002
- 2002-03-08 FR FR0202945A patent/FR2836924B1/fr not_active Expired - Lifetime
-
2003
- 2003-03-07 AU AU2003227820A patent/AU2003227820B2/en not_active Expired
- 2003-03-07 EP EP08163979.1A patent/EP1992687B1/de not_active Expired - Lifetime
- 2003-03-07 AT AT03725273T patent/ATE408004T1/de active
- 2003-03-07 CN CN2009101796309A patent/CN101676388B/zh not_active Expired - Lifetime
- 2003-03-07 WO PCT/FR2003/000735 patent/WO2003076601A1/fr not_active Ceased
- 2003-03-07 CN CNB038101203A patent/CN100562567C/zh not_active Expired - Fee Related
- 2003-03-07 CA CA2478125A patent/CA2478125C/fr not_active Expired - Fee Related
- 2003-03-07 DK DK03725273T patent/DK1483369T3/da active
- 2003-03-07 DE DE60323468T patent/DE60323468D1/de not_active Expired - Lifetime
- 2003-03-07 SI SI200331354T patent/SI1483369T1/sl unknown
- 2003-03-07 ES ES03725273T patent/ES2312775T3/es not_active Expired - Lifetime
- 2003-03-07 JP JP2003574808A patent/JP5025888B2/ja not_active Expired - Fee Related
- 2003-03-07 PT PT03725273T patent/PT1483369E/pt unknown
- 2003-03-07 EP EP03725273A patent/EP1483369B1/de not_active Expired - Lifetime
- 2003-07-24 US US10/625,847 patent/US20040058441A1/en not_active Abandoned
-
2009
- 2009-01-08 US US12/350,781 patent/US20090239297A1/en not_active Abandoned
-
2010
- 2010-03-03 US US12/717,096 patent/US9382513B2/en not_active Expired - Fee Related
-
2011
- 2011-08-09 US US13/206,056 patent/US20110294209A1/en not_active Abandoned
-
2012
- 2012-02-09 JP JP2012026135A patent/JP5784521B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003227820A1 (en) | 2003-09-22 |
| FR2836924A1 (fr) | 2003-09-12 |
| JP2005525803A (ja) | 2005-09-02 |
| SI1483369T1 (sl) | 2008-12-31 |
| US9382513B2 (en) | 2016-07-05 |
| US20120070893A9 (en) | 2012-03-22 |
| DK1483369T3 (da) | 2008-12-01 |
| EP1483369A1 (de) | 2004-12-08 |
| WO2003076601A1 (fr) | 2003-09-18 |
| US20090239297A1 (en) | 2009-09-24 |
| CA2478125A1 (fr) | 2003-09-18 |
| CN100562567C (zh) | 2009-11-25 |
| PT1483369E (pt) | 2008-12-17 |
| CN1649999A (zh) | 2005-08-03 |
| US20040058441A1 (en) | 2004-03-25 |
| CN101676388A (zh) | 2010-03-24 |
| EP1992687A3 (de) | 2009-03-25 |
| CA2478125C (fr) | 2013-05-07 |
| US20110294209A1 (en) | 2011-12-01 |
| US20100221825A1 (en) | 2010-09-02 |
| JP5025888B2 (ja) | 2012-09-12 |
| DE60323468D1 (de) | 2008-10-23 |
| CN101676388B (zh) | 2013-09-04 |
| HK1142094A1 (en) | 2010-11-26 |
| FR2836924B1 (fr) | 2005-01-14 |
| JP2012110344A (ja) | 2012-06-14 |
| AU2003227820B2 (en) | 2008-04-03 |
| JP5784521B2 (ja) | 2015-09-24 |
| EP1483369B1 (de) | 2008-09-10 |
| ES2312775T3 (es) | 2009-03-01 |
| EP1992687A2 (de) | 2008-11-19 |
| EP1992687B1 (de) | 2019-06-26 |
| WO2003076601A8 (fr) | 2005-05-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE408004T1 (de) | Vögelzell-linien und deren verwendung zur herstellung interessanter biologischer substanzen | |
| GB2432846B (en) | Medium and culture of embryonic stem cells | |
| DK1155116T3 (da) | Anvendelse af kollagenase i fremstillingen af kulturer af neurale stamceller | |
| EA199800835A1 (ru) | Среда для культуры клеток млекопитающихся, способ ее получения и смесь компонентов, композиция, способы получения, продуцирования клонального роста, размножения и изменения фенотипа гепатоцитов in vitro, клетки, фармацевтический состав, способы получения рекомбинантной клетки и генного продукта, способы использования клеток, способ трансплантации гепатоцитов, способ испытания лекарственного препарата, способ поддержания жизнеспособности дифференцированных гепатоцитов | |
| ATE419332T1 (de) | Verfahren zur zellkultivierung in einer monoschicht | |
| ATE234933T1 (de) | Verfahren zur herstellung von d-aminosäuren durch direkte gärung | |
| CN109777773A (zh) | 一种从造血干细胞分化产生nk细胞的方法及其培养基 | |
| BR0316757A (pt) | Composições de meio de cultura de célula, processo para a cultura de célula progenitoras e/ou tronco, processo para a produção de mioblastos, população de células, e uso de mioblastos | |
| ATE479743T1 (de) | Verfahren zur herstellung von zellkulturen aus biologischen präparaten für chemotherapeutische und andere assays | |
| ATE510004T1 (de) | In-vitro-techniken zur verwendung mit stammzellen | |
| GB2429211A (en) | Feeder independent extended culture of embryonic stem cells | |
| Chim et al. | Human circulating peripheral blood mononuclear cells for calvarial bone tissue engineering | |
| TW201311141A (zh) | 微藻養殖模組 | |
| ATE449162T1 (de) | Herstellung von tcr gamma delta t-zellen | |
| ATE517176T1 (de) | Verfahren zur kultivierung von geschmackszellen aus säugern | |
| DE69940352D1 (de) | Verfahren zur herstellung von gamma delta t zellen | |
| WO2004033616A8 (de) | Einrichtung zur kultivierung von zellen, insbesondere menschlicher oder tierischer zellen | |
| WO2005054447A3 (en) | Müller stem cells | |
| EP1885844A4 (de) | Herstellung und verwendung von basalmembranpartikeln | |
| CN109679899A (zh) | 一种人脂肪干细胞与脐带间充质干细胞成软骨能力的比较方法 | |
| JP2610997B2 (ja) | 肝細胞培養方法 | |
| Ismet Gürhan et al. | Serial cultivation of suspended BHK 21/13 cells in serum-reduced and serum-free medium supplemented with various membrane protective agents | |
| JPS61124374A (ja) | 酢酸からメタンを生成する微生物の培養法 | |
| JPS5933353B2 (ja) | クロレラの培養法 | |
| CN1717478A (zh) | 用于人类胚胎干细胞体外培养的饲养细胞层以及培养胚胎干细胞的方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1483369 Country of ref document: EP |