ATE408615T1 - Steroidale verbindungen zur hemmung von steroid sulfotase - Google Patents

Steroidale verbindungen zur hemmung von steroid sulfotase

Info

Publication number: ATE408615T1
Authority: AT; Austria
Prior art keywords: sulfotase; steroidal compounds; inhibiting steroid; group; steroid
Prior art date: 2001-10-18

Application number

AT06000817T

Other languages

English (en)

Inventor

Barry Victor Lloyd Potter

Michael John Reed

Lok Wai Lawrence Woo

Original Assignee

Sterix Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-10-18

Filing date

2002-10-17

Publication date

2008-10-15

2001-10-18 Priority claimed from PCT/GB2001/004645 external-priority patent/WO2002032409A2/en

2001-10-18 Priority claimed from GB0125073A external-priority patent/GB0125073D0/en

2002-04-23 Priority claimed from GB0209274A external-priority patent/GB0209274D0/en

2002-10-17 Application filed by Sterix Ltd filed Critical Sterix Ltd

2008-10-15 Application granted granted Critical

2008-10-15 Publication of ATE408615T1 publication Critical patent/ATE408615T1/de

Links

150000001875 compounds Chemical class 0.000 title abstract 2
230000002401 inhibitory effect Effects 0.000 title 1
230000003637 steroidlike Effects 0.000 title 1
150000003431 steroids Chemical class 0.000 title 1
ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical group OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 abstract 1
IIACRCGMVDHOTQ-UHFFFAOYSA-N sulfamic acid Chemical group NS(O)(=O)=O IIACRCGMVDHOTQ-UHFFFAOYSA-N 0.000 abstract 1
125000000565 sulfonamide group Chemical group 0.000 abstract 1
125000001273 sulfonato group Chemical group [O-]S(*)(=O)=O 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)

AT06000817T 2001-10-18 2002-10-17 Steroidale verbindungen zur hemmung von steroid sulfotase ATE408615T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
PCT/GB2001/004645 WO2002032409A2 (en)	2000-10-20	2001-10-18	Use of compound in the manufacture of a pharmaceutical for inhibiting steroid sulphatase and steroid dehydrogenase activity
GB0125073A GB0125073D0 (en)	2001-10-18	2001-10-18	Compound
GB0209274A GB0209274D0 (en)	2002-04-23	2002-04-23	Compound

Publications (1)

Publication Number	Publication Date
ATE408615T1 true ATE408615T1 (de)	2008-10-15

Family

ID=34066588

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT06000817T ATE408615T1 (de)	2001-10-18	2002-10-17	Steroidale verbindungen zur hemmung von steroid sulfotase

Country Status (7)

Country	Link
US (3)	US7098218B2 (de)
EP (1)	EP1657247B1 (de)
AT (1)	ATE408615T1 (de)
CA (1)	CA2463227C (de)
DE (1)	DE60229009D1 (de)
DK (1)	DK1448592T3 (de)
ES (2)	ES2258174T3 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2258174T3 (es) *	2001-10-18	2006-08-16	Sterix Limited	Compuestos esteroideos para la inhibicion de la sulfatasa esteroidea.
GB0604142D0 (en) *	2006-03-01	2006-04-12	Sterix Ltd	Compound
WO2009055366A1 (en) *	2007-10-22	2009-04-30	Translational Genomics Research Institute (Tgen)	Method and kit used in performing high resolution genomic profiling of clonal cell populations in heterogeneous tissues

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US1972884A (en) *	1932-03-31	1934-09-11	Guggenhelm Brothers	Recovery of sulphur
AT314746B (de)	1970-06-18	1974-04-25	Richter Gedeon Vegyeszet	Verfahren zur Herstellung von neuen D-Homo-imid-Derivaten mit Sterangerüst
US3972884A (en)	1974-09-06	1976-08-03	Eli Lilly And Company	D-homo-aza-steroids
US4039547A (en)	1974-09-06	1977-08-02	Eli Lilly And Company	24-Methyl-14a-aza-D-homo-cholest-8(9)-enes
HU175287B (hu)	1977-08-18	1980-06-28	Richter Gedeon Vegyeszet	Sposob poluchenija novykh proizvodnykh 3-amino-17al'fa-aza-d-gomo-androstana,dalee ikh kislotoaddicionnykh i chetvjortichnykh solej
US5140022A (en)	1990-10-01	1992-08-18	Anaquest, Inc.	3-acyclic or cyclicaminomethyl-17a-lower-alkyl-17a-aza-d-homo-5-alpha-androstanes
GB9118478D0 (en) *	1991-08-29	1991-10-16	Imperial College	Steroid sulphatase inhibitors
GB0025788D0 (en) *	2000-10-20	2000-12-06	Sterix Ltd	Use
ES2258174T3 (es) *	2001-10-18	2006-08-16	Sterix Limited	Compuestos esteroideos para la inhibicion de la sulfatasa esteroidea.

2002
- 2002-10-17 ES ES02801418T patent/ES2258174T3/es not_active Expired - Lifetime
- 2002-10-17 AT AT06000817T patent/ATE408615T1/de not_active IP Right Cessation
- 2002-10-17 DE DE60229009T patent/DE60229009D1/de not_active Expired - Lifetime
- 2002-10-17 CA CA2463227A patent/CA2463227C/en not_active Expired - Fee Related
- 2002-10-17 ES ES06000817T patent/ES2314760T3/es not_active Expired - Lifetime
- 2002-10-17 DK DK02801418T patent/DK1448592T3/da active
- 2002-10-17 EP EP06000817A patent/EP1657247B1/de not_active Expired - Lifetime
2004
- 2004-04-16 US US10/825,758 patent/US7098218B2/en not_active Expired - Fee Related
2006
- 2006-01-11 US US11/329,982 patent/US7276513B2/en not_active Expired - Fee Related
2007
- 2007-09-14 US US11/855,603 patent/US8124614B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CA2463227C (en)	2010-08-10
US20050014776A1 (en)	2005-01-20
ES2314760T3 (es)	2009-03-16
EP1657247B1 (de)	2008-09-17
US20080312266A1 (en)	2008-12-18
US8124614B2 (en)	2012-02-28
DE60229009D1 (de)	2008-10-30
US7276513B2 (en)	2007-10-02
CA2463227A1 (en)	2003-04-24
DK1448592T3 (da)	2006-07-17
HK1084955A1 (en)	2006-08-11
US7098218B2 (en)	2006-08-29
EP1657247A1 (de)	2006-05-17
US20070105886A1 (en)	2007-05-10
ES2258174T3 (es)	2006-08-16

Legal Events

Date	Code	Title	Description
2009-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties
2010-01-15	REN	Ceased due to non-payment of the annual fee

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