DK1448592T3 - Steroide forbindelser til inhibering af steroidsulfataser - Google Patents

Steroide forbindelser til inhibering af steroidsulfataser

Info

Publication number: DK1448592T3
Authority: DK; Denmark
Prior art keywords: steroidal compounds; inhibiting steroid; group; sulfatases; steroid sulfatases
Prior art date: 2001-10-18

Application number

DK02801418T

Other languages

Danish (da)

English (en)

Inventor

Barry V L Potter

Michael J Reed

Lok Wai L Woo

Original Assignee

Sterix Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-10-18

Filing date

2002-10-17

Publication date

2006-07-17

2001-10-18 Priority claimed from GB0125073A external-priority patent/GB0125073D0/en

2001-10-18 Priority claimed from PCT/GB2001/004645 external-priority patent/WO2002032409A2/en

2002-04-23 Priority claimed from GB0209274A external-priority patent/GB0209274D0/en

2002-10-17 Application filed by Sterix Ltd filed Critical Sterix Ltd

2006-07-17 Application granted granted Critical

2006-07-17 Publication of DK1448592T3 publication Critical patent/DK1448592T3/da

Links

150000001875 compounds Chemical class 0.000 title abstract 2
108010087999 Steryl-Sulfatase Proteins 0.000 title 1
102100038021 Steryl-sulfatase Human genes 0.000 title 1
230000002401 inhibitory effect Effects 0.000 title 1
230000003637 steroidlike Effects 0.000 title 1
ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical group OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 abstract 1
IIACRCGMVDHOTQ-UHFFFAOYSA-N sulfamic acid Chemical group NS(O)(=O)=O IIACRCGMVDHOTQ-UHFFFAOYSA-N 0.000 abstract 1
125000000565 sulfonamide group Chemical group 0.000 abstract 1
125000001273 sulfonato group Chemical group [O-]S(*)(=O)=O 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Immunology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)

DK02801418T 2001-10-18 2002-10-17 Steroide forbindelser til inhibering af steroidsulfataser DK1448592T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB0125073A GB0125073D0 (en)	2001-10-18	2001-10-18	Compound
PCT/GB2001/004645 WO2002032409A2 (en)	2000-10-20	2001-10-18	Use of compound in the manufacture of a pharmaceutical for inhibiting steroid sulphatase and steroid dehydrogenase activity
GB0209274A GB0209274D0 (en)	2002-04-23	2002-04-23	Compound

Publications (1)

Publication Number	Publication Date
DK1448592T3 true DK1448592T3 (da)	2006-07-17

Family

ID=34066588

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK02801418T DK1448592T3 (da)	2001-10-18	2002-10-17	Steroide forbindelser til inhibering af steroidsulfataser

Country Status (7)

Country	Link
US (3)	US7098218B2 (de)
EP (1)	EP1657247B1 (de)
AT (1)	ATE408615T1 (de)
CA (1)	CA2463227C (de)
DE (1)	DE60229009D1 (de)
DK (1)	DK1448592T3 (de)
ES (2)	ES2258174T3 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2258174T3 (es) *	2001-10-18	2006-08-16	Sterix Limited	Compuestos esteroideos para la inhibicion de la sulfatasa esteroidea.
GB0604142D0 (en) *	2006-03-01	2006-04-12	Sterix Ltd	Compound
WO2009055366A1 (en) *	2007-10-22	2009-04-30	Translational Genomics Research Institute (Tgen)	Method and kit used in performing high resolution genomic profiling of clonal cell populations in heterogeneous tissues

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US1972884A (en) *	1932-03-31	1934-09-11	Guggenhelm Brothers	Recovery of sulphur
AT314746B (de)	1970-06-18	1974-04-25	Richter Gedeon Vegyeszet	Verfahren zur Herstellung von neuen D-Homo-imid-Derivaten mit Sterangerüst
US3972884A (en)	1974-09-06	1976-08-03	Eli Lilly And Company	D-homo-aza-steroids
US4039547A (en) *	1974-09-06	1977-08-02	Eli Lilly And Company	24-Methyl-14a-aza-D-homo-cholest-8(9)-enes
HU175287B (hu)	1977-08-18	1980-06-28	Richter Gedeon Vegyeszet	Sposob poluchenija novykh proizvodnykh 3-amino-17al'fa-aza-d-gomo-androstana,dalee ikh kislotoaddicionnykh i chetvjortichnykh solej
US5140022A (en)	1990-10-01	1992-08-18	Anaquest, Inc.	3-acyclic or cyclicaminomethyl-17a-lower-alkyl-17a-aza-d-homo-5-alpha-androstanes
GB9118478D0 (en) *	1991-08-29	1991-10-16	Imperial College	Steroid sulphatase inhibitors
GB0025788D0 (en) *	2000-10-20	2000-12-06	Sterix Ltd	Use
ES2258174T3 (es) *	2001-10-18	2006-08-16	Sterix Limited	Compuestos esteroideos para la inhibicion de la sulfatasa esteroidea.

2002
- 2002-10-17 ES ES02801418T patent/ES2258174T3/es not_active Expired - Lifetime
- 2002-10-17 DE DE60229009T patent/DE60229009D1/de not_active Expired - Lifetime
- 2002-10-17 EP EP06000817A patent/EP1657247B1/de not_active Expired - Lifetime
- 2002-10-17 AT AT06000817T patent/ATE408615T1/de not_active IP Right Cessation
- 2002-10-17 ES ES06000817T patent/ES2314760T3/es not_active Expired - Lifetime
- 2002-10-17 CA CA2463227A patent/CA2463227C/en not_active Expired - Fee Related
- 2002-10-17 DK DK02801418T patent/DK1448592T3/da active
2004
- 2004-04-16 US US10/825,758 patent/US7098218B2/en not_active Expired - Fee Related
2006
- 2006-01-11 US US11/329,982 patent/US7276513B2/en not_active Expired - Fee Related
2007
- 2007-09-14 US US11/855,603 patent/US8124614B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE60229009D1 (de)	2008-10-30
EP1657247A1 (de)	2006-05-17
US20080312266A1 (en)	2008-12-18
CA2463227C (en)	2010-08-10
US20070105886A1 (en)	2007-05-10
US8124614B2 (en)	2012-02-28
CA2463227A1 (en)	2003-04-24
ATE408615T1 (de)	2008-10-15
ES2314760T3 (es)	2009-03-16
ES2258174T3 (es)	2006-08-16
US7276513B2 (en)	2007-10-02
EP1657247B1 (de)	2008-09-17
US7098218B2 (en)	2006-08-29
US20050014776A1 (en)	2005-01-20
HK1084955A1 (en)	2006-08-11

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