ATE408688T1 - Polypeptide zur modulierung des überlebens von zellen - Google Patents
Polypeptide zur modulierung des überlebens von zellenInfo
- Publication number
- ATE408688T1 ATE408688T1 AT99953434T AT99953434T ATE408688T1 AT E408688 T1 ATE408688 T1 AT E408688T1 AT 99953434 T AT99953434 T AT 99953434T AT 99953434 T AT99953434 T AT 99953434T AT E408688 T1 ATE408688 T1 AT E408688T1
- Authority
- AT
- Austria
- Prior art keywords
- death
- p75ntr
- cell survival
- present
- well
- Prior art date
Links
- 230000004083 survival effect Effects 0.000 title abstract 6
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 229920001184 polypeptide Polymers 0.000 title abstract 2
- 102000007339 Nerve Growth Factor Receptors Human genes 0.000 abstract 6
- 108010032605 Nerve Growth Factor Receptors Proteins 0.000 abstract 6
- 210000004027 cell Anatomy 0.000 abstract 6
- 230000034994 death Effects 0.000 abstract 6
- 230000011664 signaling Effects 0.000 abstract 4
- 230000030833 cell death Effects 0.000 abstract 3
- 230000001404 mediated effect Effects 0.000 abstract 2
- 230000001737 promoting effect Effects 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 210000003061 neural cell Anatomy 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000009131 signaling function Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- AIDS & HIV (AREA)
- Urology & Nephrology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Biotechnology (AREA)
- Hospice & Palliative Care (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPP6353A AUPP635398A0 (en) | 1998-10-06 | 1998-10-06 | A method of modulating cell survival and reagents useful for same |
| AUPP6351A AUPP635198A0 (en) | 1998-10-07 | 1998-10-07 | A method of modulating cell survival and reagents useful for same-ii |
| AUPQ0701A AUPQ070199A0 (en) | 1999-06-01 | 1999-06-01 | A method of modulating cell survival and reagents useful for same-iii |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE408688T1 true ATE408688T1 (de) | 2008-10-15 |
Family
ID=27158107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99953434T ATE408688T1 (de) | 1998-10-06 | 1999-10-05 | Polypeptide zur modulierung des überlebens von zellen |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20020137188A1 (de) |
| EP (1) | EP1121434B1 (de) |
| AT (1) | ATE408688T1 (de) |
| CA (1) | CA2345379C (de) |
| DE (1) | DE69939593D1 (de) |
| WO (1) | WO2000020578A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000020578A1 (en) | 1998-10-06 | 2000-04-13 | The Walter And Eliza Hall Institute Of Medical Research | A method of modulating cell survival and reagents useful for same |
| US6472176B2 (en) * | 2000-12-14 | 2002-10-29 | Genvec, Inc. | Polynucleotide encoding chimeric protein and related vector, cell, and method of expression thereof |
| AU2002339213A1 (en) * | 2001-08-09 | 2003-02-24 | Genset S.A. | Migenix agonists and antagonists for use in the treatment of metabolic disorders |
| AU2003222681B8 (en) * | 2002-05-14 | 2009-06-18 | The University Of Queensland | A method of treatment |
| AUPS230702A0 (en) * | 2002-05-14 | 2002-06-13 | Walter And Eliza Hall Institute Of Medical Research, The | A method of treatment |
| DE602005010436D1 (de) * | 2004-07-14 | 2008-11-27 | Janssen Pharmaceutica Nv | P75ntr-screeningtest zur identifizierung von modulatoren der apoptose |
| WO2014049556A2 (en) * | 2012-09-28 | 2014-04-03 | The University Of Queensland | Neurotrophin-tyrosine kinase receptor signaling |
| US10786543B2 (en) * | 2015-09-22 | 2020-09-29 | The Johns Hopkins University | P75NTR antagonists and treatment of acute and chronic cardiac disease |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5606023A (en) * | 1994-05-24 | 1997-02-25 | Thomas Jefferson University | Mutant tumor necrosis factor proteins |
| EP0846169B1 (de) * | 1995-08-04 | 2003-03-19 | Lek, Tovarna Farmacevtskih in Kemicnih Izdelkov, D.D. | Monoklonale antikörper gegen lösliche tnf-alpha rezeptoren p55 und p75 als auch gegen tnf-alpha und dessen analogen |
| WO2000020578A1 (en) | 1998-10-06 | 2000-04-13 | The Walter And Eliza Hall Institute Of Medical Research | A method of modulating cell survival and reagents useful for same |
| AU772811B2 (en) | 1998-10-06 | 2004-05-06 | University Of Queensland, The | A method of modulating cell survival and reagents useful for same |
-
1999
- 1999-10-05 WO PCT/AU1999/000860 patent/WO2000020578A1/en not_active Ceased
- 1999-10-05 EP EP99953434A patent/EP1121434B1/de not_active Expired - Lifetime
- 1999-10-05 DE DE69939593T patent/DE69939593D1/de not_active Expired - Lifetime
- 1999-10-05 AT AT99953434T patent/ATE408688T1/de not_active IP Right Cessation
- 1999-10-05 CA CA2345379A patent/CA2345379C/en not_active Expired - Fee Related
-
2001
- 2001-03-30 US US09/821,831 patent/US20020137188A1/en not_active Abandoned
-
2004
- 2004-08-18 US US10/921,065 patent/US7919471B2/en not_active Expired - Fee Related
-
2010
- 2010-09-17 US US12/885,194 patent/US8299027B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20020137188A1 (en) | 2002-09-26 |
| CA2345379A1 (en) | 2000-04-13 |
| DE69939593D1 (de) | 2008-10-30 |
| EP1121434A1 (de) | 2001-08-08 |
| US20050090442A1 (en) | 2005-04-28 |
| CA2345379C (en) | 2011-12-06 |
| EP1121434B1 (de) | 2008-09-17 |
| EP1121434A4 (de) | 2005-03-02 |
| US7919471B2 (en) | 2011-04-05 |
| US20110172143A1 (en) | 2011-07-14 |
| US8299027B2 (en) | 2012-10-30 |
| WO2000020578A1 (en) | 2000-04-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties | ||
| REN | Ceased due to non-payment of the annual fee |