ATE409462T1 - Pharmazeutische zusammensetzungen mit verbesserter leistung enthaltend ein hpmca polymer - Google Patents
Pharmazeutische zusammensetzungen mit verbesserter leistung enthaltend ein hpmca polymerInfo
- Publication number
- ATE409462T1 ATE409462T1 AT05742034T AT05742034T ATE409462T1 AT E409462 T1 ATE409462 T1 AT E409462T1 AT 05742034 T AT05742034 T AT 05742034T AT 05742034 T AT05742034 T AT 05742034T AT E409462 T1 ATE409462 T1 AT E409462T1
- Authority
- AT
- Austria
- Prior art keywords
- pharmaceutical compositions
- improved performance
- polymers
- hpmca
- performance containing
- Prior art date
Links
- 229920000642 polymer Polymers 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- -1 hydroxypropoxy, methoxy, acetyl Chemical class 0.000 abstract 2
- 229920000639 hydroxypropylmethylcellulose acetate succinate Polymers 0.000 abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 abstract 1
- ZUAAPNNKRHMPKG-UHFFFAOYSA-N acetic acid;butanedioic acid;methanol;propane-1,2-diol Chemical compound OC.CC(O)=O.CC(O)CO.OC(=O)CCC(O)=O ZUAAPNNKRHMPKG-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B13/00—Preparation of cellulose ether-esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B11/00—Preparation of cellulose ethers
- C08B11/02—Alkyl or cycloalkyl ethers
- C08B11/04—Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals
- C08B11/08—Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals with hydroxylated hydrocarbon radicals; Esters, ethers, or acetals thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
- C08L1/08—Cellulose derivatives
- C08L1/26—Cellulose ethers
- C08L1/28—Alkyl ethers
- C08L1/284—Alkyl ethers with hydroxylated hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
- C08L1/08—Cellulose derivatives
- C08L1/32—Cellulose ether-esters
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Materials Engineering (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57554104P | 2004-05-28 | 2004-05-28 | |
| US58654904P | 2004-07-09 | 2004-07-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE409462T1 true ATE409462T1 (de) | 2008-10-15 |
Family
ID=35451370
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05742034T ATE409462T1 (de) | 2004-05-28 | 2005-05-18 | Pharmazeutische zusammensetzungen mit verbesserter leistung enthaltend ein hpmca polymer |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8207232B2 (de) |
| EP (1) | EP1753402B1 (de) |
| JP (1) | JP2008501009A (de) |
| AT (1) | ATE409462T1 (de) |
| CA (1) | CA2568007A1 (de) |
| DE (1) | DE602005010074D1 (de) |
| MX (1) | MXPA06013891A (de) |
| WO (1) | WO2005115330A2 (de) |
Families Citing this family (94)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA03011784A (es) * | 2001-06-22 | 2004-04-02 | Pfizer Prod Inc | Composiciones farmaceuticas de dispersiones de farmacos y polimeros neutros. |
| EP1844078B1 (de) * | 2005-02-03 | 2016-09-28 | Bend Research, Inc | Pharmazeutische zusammensetzungen mit erhöhter leistung |
| JP2010526848A (ja) * | 2007-05-11 | 2010-08-05 | エフ．ホフマン−ラ ロシュ アーゲー | 難溶性薬物用の医薬組成物 |
| WO2009125415A1 (en) * | 2008-04-07 | 2009-10-15 | Hetero Research Foundation | Amorphous form of sildenafil citrate |
| WO2010102065A1 (en) | 2009-03-05 | 2010-09-10 | Bend Research, Inc. | Pharmaceutical compositions of dextran polymer derivatives |
| PT3130396T (pt) | 2009-03-27 | 2021-05-12 | Bend Res Inc | Processo de secagem por pulverização |
| KR101682466B1 (ko) * | 2010-02-01 | 2016-12-05 | 롯데정밀화학 주식회사 | 아세틸화 셀룰로오스 에테르 및 이를 포함하는 물품 |
| WO2011148253A2 (en) | 2010-05-25 | 2011-12-01 | Aurobindo Pharma Limited | Solid dosage forms of antipsychotics |
| WO2011159626A1 (en) | 2010-06-14 | 2011-12-22 | Bend Research, Inc. | Hydroxypropyl methyl cellulose acetate succinate with enhanced acetate and succinate substitution |
| WO2012031133A2 (en) | 2010-09-03 | 2012-03-08 | Bench Research, Inc. | Spray-drying apparatus and methods of using the same |
| WO2012031129A2 (en) | 2010-09-03 | 2012-03-08 | Bend Research, Inc. | Spray-drying apparatus and methods of using the same |
| US9248584B2 (en) | 2010-09-24 | 2016-02-02 | Bend Research, Inc. | High-temperature spray drying process and apparatus |
| KR101088845B1 (ko) * | 2011-01-21 | 2011-12-06 | 원광대학교산학협력단 | 황금 추출물의 속효성 고체 분산체, 이를 함유한 경구용 제제 및 이들의 제조방법 |
| US8409560B2 (en) | 2011-03-08 | 2013-04-02 | Zalicus Pharmaceuticals Ltd. | Solid dispersion formulations and methods of use thereof |
| WO2012122279A1 (en) | 2011-03-08 | 2012-09-13 | Zalicus Pharmaceuticals Ltd. | Solid dispersion formulations and methods of use thereof |
| US9060938B2 (en) | 2011-05-10 | 2015-06-23 | Bend Research, Inc. | Pharmaceutical compositions of active agents and cationic dextran polymer derivatives |
| US9453081B2 (en) | 2012-03-27 | 2016-09-27 | Dow Global Technologies Llc | Process of preparing an ester of a cellulose ether |
| WO2013154977A1 (en) | 2012-04-11 | 2013-10-17 | Dow Global Technologies Llc | Novel sustained release dosage forms |
| JP6185559B2 (ja) | 2012-04-11 | 2017-08-23 | ダウ グローバル テクノロジーズ エルエルシー | 有機希釈剤およびセルロースエーテルを含む組成物 |
| EP2836517B1 (de) | 2012-04-11 | 2016-07-27 | Dow Global Technologies LLC | Schmelzextrudierte zusammensetzung mit einem celluloseether |
| US9320799B2 (en) | 2012-04-11 | 2016-04-26 | Dow Global Technologies Llc | Esterified cellulose ethers having a specific substituent distribution |
| BR112014032017A2 (pt) | 2012-07-17 | 2017-06-27 | Dow Global Technologies Llc | dispersão sólida, dispersão sólida extrudada e processo para produzir uma dispersão sólida |
| CN104603194B (zh) | 2012-07-17 | 2017-11-24 | 陶氏环球技术有限责任公司 | 包含有机液体稀释剂和低粘度纤维素醚的组合物 |
| CN102807625A (zh) * | 2012-08-23 | 2012-12-05 | 浙江中维药业有限公司 | 一种醋酸羟丙甲纤维素琥珀酸酯的制备方法 |
| EP2888291A1 (de) | 2012-08-24 | 2015-07-01 | Dow Global Technologies LLC | Verfahren zur herstellung eines esters aus einem celluloseether unter verwendung einer aliphatischen carbonsäure |
| BR112015002055A2 (pt) * | 2012-08-24 | 2017-07-04 | Dow Global Technologies Llc | acetato succinato de hidroxialquil metil celulose, composição, dispersão sólida, processo para produzir uma dispersão sólida, forma de dosagem e cápsula de envoltório |
| CN107602710A (zh) * | 2012-08-24 | 2018-01-19 | 陶氏环球技术有限责任公司 | 新的具有高分子量和均匀性的酯化纤维素醚 |
| EP2888289B1 (de) | 2012-08-24 | 2019-08-07 | Dow Global Technologies LLC | Teilvernetzte veresterte celluloseether |
| MX2015002426A (es) | 2012-08-24 | 2015-06-22 | Dow Global Technologies Llc | Procedimiento para preparar un eter de celulosa esterificado en presencia de un carboxilato de metal alcalino y un acido carboxilico alifatico. |
| US9737538B2 (en) * | 2013-02-12 | 2017-08-22 | Bend Research, Inc. | Solid dispersions of low-water solubility actives |
| WO2014126969A1 (en) | 2013-02-12 | 2014-08-21 | Bend Research, Inc. | Solid dispersions of low-water solubility actives |
| JP6456849B2 (ja) * | 2013-03-01 | 2019-01-23 | ハーキュリーズ・インコーポレーテッドＨｅｒｃｕｌｅｓ Ｉｎｃｏｒｐｏｒａｔｅｄ | 高められた性能及び改善された加工性を有する医薬組成物 |
| BR112015019807B1 (pt) * | 2013-03-07 | 2020-12-08 | Dow Global Technologies Llc | acetato succinato de hidroxipropil metilcelulose, composição, dispersão sólida, forma de dosagem e envoltório de cápsula |
| JP6334574B2 (ja) * | 2013-03-07 | 2018-05-30 | ダウ グローバル テクノロジーズ エルエルシー | 新規の超高分子量のエステル化セルロースエーテル |
| CN105025887B (zh) * | 2013-03-07 | 2017-07-28 | 陶氏环球技术有限责任公司 | 新颖极低粘度酯化纤维素醚 |
| WO2014137789A1 (en) * | 2013-03-07 | 2014-09-12 | Dow Global Technologies Llc | Novel esterified cellulose ethers of low viscosity and high molecular weight |
| EP2997046B1 (de) | 2013-05-14 | 2019-09-25 | Dow Global Technologies LLC | Mit dicarbonsäuren veresterte celluloseether |
| CN105283203B (zh) | 2013-06-03 | 2018-12-28 | 信越化学工业株式会社 | 用于热熔挤出的组合物以及通过使用该组合物制备热熔挤出物的方法 |
| CN105829352B (zh) * | 2013-09-23 | 2018-04-10 | 陶氏环球技术有限责任公司 | 用于从反应产物混合物中回收酯化纤维素醚的方法 |
| US10610491B2 (en) | 2013-09-25 | 2020-04-07 | Dow Global Technologies Llc | Composition comprising an organic liquid diluent and a specific hydroxyalkyl methylcellulose |
| WO2015061602A1 (en) | 2013-10-23 | 2015-04-30 | Dow Global Technologies Llc | Methods, systems, and devices for designing molecules |
| JP6212538B2 (ja) * | 2013-12-20 | 2017-10-11 | 株式会社ダイセル | 脂質代謝改善作用を有する栄養組成物 |
| KR102286952B1 (ko) * | 2013-12-31 | 2021-08-09 | 롯데정밀화학 주식회사 | 입도분포가 조절된 히드록시프로필 메틸셀룰로오스 아세테이트 숙시네이트(hpmcas) 입자의 제조방법 및 hpmcas 분말 |
| WO2015126576A1 (en) | 2014-02-20 | 2015-08-27 | Dow Global Technologies Llc | Novel esterified cellulose ethers of high molecular weight and homogeneity |
| EP3130236B1 (de) * | 2014-03-24 | 2020-08-05 | Daicel Corporation | Ernährungszusammensetzung |
| GR1008554B (el) | 2014-06-12 | 2015-09-03 | ΦΑΡΜΑΤΕΝ ΑΝΩΝΥΜΟΣ ΒΙΟΜΗΧΑΝΙΚΗ ΚΑΙ ΕΜΠΟΡΙΚΗ ΕΤΑΙΡΕΙΑ ΦΑΡΜΑΚΕΥΤΙΚΩΝ ΙΑΤΡΙΚΩΝ ΚΑΙ ΚΑΛΛΥΝΤΙΚΩΝ ΠΡΟΪΟΝΤΩΝ με δ.τ. ΦΑΡΜΑΤΕΝ, | Φαρμακευτικο σκευασμα περιεχον εναν αντιμυκητιασικο παραγοντα τριaζολης και μεθοδος για την παρασκευη αυτου |
| EP3186285B1 (de) | 2014-08-27 | 2022-04-13 | Nutrition & Biosciences USA 1, LLC | Veresterte celluloseether mit niedrigem unlöslichem acetongehalt |
| WO2016069343A1 (en) | 2014-10-31 | 2016-05-06 | Dow Global Technologies Llc | Efficient process for preparing an ester of a cellulose ether |
| CA2962719A1 (en) | 2014-10-31 | 2016-05-06 | Bend Research Inc. | Process for forming active domains dispersed in a matrix |
| EP3212674B1 (de) | 2014-10-31 | 2018-08-22 | Dow Global Technologies LLC | Verfahren zur herstellung eines esters aus einem celluloseether |
| MX356115B (es) * | 2014-10-31 | 2018-05-15 | Dow Global Technologies Llc | Proceso para producir un succinato de acetato de eter de celulosa. |
| JP6203702B2 (ja) | 2014-11-18 | 2017-09-27 | 信越化学工業株式会社 | ヒプロメロース酢酸エステルコハク酸エステルを用いたスプレードライ用溶液及び固体分散体の製造方法 |
| CN113735982A (zh) | 2015-01-08 | 2021-12-03 | 陶氏环球技术有限责任公司 | 用于生产具有降低含量的水不溶性颗粒的水溶性纤维素衍生物的方法 |
| BR112017018146A2 (pt) | 2015-03-16 | 2018-04-10 | Dow Global Technologies Llc | processo para a preparação de um éter de celulose esterificado na presença de um ácido carboxílico alifático |
| WO2016148970A1 (en) | 2015-03-16 | 2016-09-22 | Dow Global Technologies Llc | Aqueous solution of an esterified cellulose ether |
| MX2017011128A (es) | 2015-03-16 | 2017-11-28 | Dow Global Technologies Llc | Eteres de celulosa esterificada de gelificacion. |
| MX2017011095A (es) | 2015-03-16 | 2017-11-10 | Dow Global Technologies Llc | Eteres de celulosa esterificados solubles en agua que tienen grado bajo de neutralizacion. |
| MX2017011092A (es) | 2015-03-16 | 2017-11-10 | Dow Global Technologies Llc | Proceso para fraccionar un eter esterificado de celulosa. |
| JP6356923B2 (ja) | 2015-03-16 | 2018-07-11 | ダウ グローバル テクノロジーズ エルエルシー | 水溶性エステル化セルロースエーテル |
| CN107567462B (zh) | 2015-05-15 | 2020-10-16 | 陶氏环球技术有限责任公司 | 用于制造具有极高分子量和低粘度的酯化纤维素醚的方法 |
| JP6737810B2 (ja) * | 2015-05-15 | 2020-08-12 | ダウ グローバル テクノロジーズ エルエルシー | 高分子量のエステル化セルロースエーテルを調製するプロセス |
| US20180273646A1 (en) | 2015-09-24 | 2018-09-27 | Dow Global Technologies Llc. | Process for preparing an ester of a cellulose ether in the presence of acetic acid and a reaction catalyst |
| BR112018005463A2 (pt) | 2015-10-02 | 2018-10-09 | Dow Global Technologies Llc | composição aquosa compreendendo éter de celulose esterificado disperso |
| BR112018010354A2 (pt) | 2015-12-08 | 2018-12-04 | Dow Global Technologies Llc | composições compreendendo éteres de celulose e éteres de celulose esterificados solúveis em água |
| WO2017146853A1 (en) | 2016-02-24 | 2017-08-31 | Dow Global Technologies Llc | Aqueous composition comprising water-soluble esterified cellulose ethers |
| US10604588B2 (en) * | 2016-04-05 | 2020-03-31 | Shin-Etsu Chemical Co., Ltd. | Hypromellose acetate succinate powder excellent in dissolved state and production method thereof, and production methods for composition for solid dispersion, coating composition, drug-containing particle, and solid preparation |
| WO2017181141A2 (en) | 2016-04-15 | 2017-10-19 | Novira Therapeutics, Inc. | Combinations and methods comprising a capsid assembly inhibitor |
| EP3463314B1 (de) | 2016-05-25 | 2020-07-22 | Dow Global Technologies LLC | Wässrige lösung von celluloseetheracetat |
| GB201609222D0 (en) | 2016-05-25 | 2016-07-06 | F2G Ltd | Pharmaceutical formulation |
| BR112018074763A2 (pt) | 2016-06-23 | 2019-03-06 | Dow Global Technologies Llc | éteres de celulose esterificados que compreendem grupos ftalila |
| WO2017223018A1 (en) | 2016-06-23 | 2017-12-28 | Dow Global Technologies Llc | Esterified cellulose ethers comprising trimellityl groups |
| CN106317229A (zh) * | 2016-08-22 | 2017-01-11 | 四川北方硝化棉股份有限公司 | 一种制备低取代度醋酸纤维素的生产方法 |
| JP2019529592A (ja) | 2016-08-23 | 2019-10-17 | ダウ グローバル テクノロジーズ エルエルシー | セルロースエーテルアセテートフタレート |
| WO2018039214A1 (en) | 2016-08-23 | 2018-03-01 | Dow Global Technologies Llc | Esterified cellulose ethers comprising maleyl groups |
| JP2019531390A (ja) | 2016-10-18 | 2019-10-31 | ダウ グローバル テクノロジーズ エルエルシー | エステル化セルロースエーテルを調製する効率的な方法 |
| KR102490265B1 (ko) | 2016-11-02 | 2023-01-20 | 신에쓰 가가꾸 고교 가부시끼가이샤 | 히프로멜로오스아세트산에스테르숙신산에스테르 및 제조 방법 |
| WO2018170060A1 (en) | 2017-03-17 | 2018-09-20 | Dow Global Technologies Llc | Process for recovering an esterified cellulose ether from a reaction product mixture |
| WO2018170083A1 (en) | 2017-03-17 | 2018-09-20 | Dow Global Technologies Llc | Process for recovering an esterified cellulose ether from a reaction product mixture |
| EP3596132B1 (de) | 2017-03-17 | 2021-05-05 | Nutrition & Biosciences USA 1, LLC | Verfahren zur rückgewinnung eines veresterten celluloseethers aus einem reaktionsproduktgemisch |
| SG11202007097QA (en) | 2018-03-14 | 2020-08-28 | Janssen Sciences Ireland Unlimited Co | Capsid assembly modulator dosing regimen |
| CN112118830B (zh) * | 2018-05-14 | 2023-11-10 | 比利时胶囊公司 | 高活性剂载量的固体剂型 |
| WO2020117736A1 (en) | 2018-12-04 | 2020-06-11 | DDP Specialty Electronic Materials US, Inc. | Hydroxypropyl methylcellulose acetate succinates of very high molecular weight |
| WO2020131785A1 (en) * | 2018-12-18 | 2020-06-25 | DDP Specialty Electronic Materials US, Inc. | A sustained release composition comprising a hydroxypropyl methylcellulose acetate succinate |
| WO2020131801A1 (en) * | 2018-12-18 | 2020-06-25 | DDP Specialty Electronic Materials US, Inc. | A sustained release composition comprising a hydroxypropyl methylcellulose acetate succinate |
| CA3136632A1 (en) | 2019-04-11 | 2020-10-15 | Goldfinch Bio, Inc. | Spray-dried formulation of a pyridazinone trpc5 inhibitor |
| US11819503B2 (en) | 2019-04-23 | 2023-11-21 | F2G Ltd | Method of treating coccidioides infection |
| WO2021118915A1 (en) | 2019-12-09 | 2021-06-17 | Nutrition & Biosciences Usa 1, Llc | Hydroxypropyl alkyl cellulose acetate succinate heteropolymers |
| EP4073167A1 (de) | 2019-12-09 | 2022-10-19 | Nutrition & Biosciences USA 1, LLC | Zusammensetzung mit einer hochsubstituierten hydroxypropylmethylcellulose und einem zuckeralkohol |
| IL294928A (en) | 2020-01-24 | 2022-09-01 | Nanocopoeia Llc | Amorphous solid dispersions of dasatinib and uses thereof |
| IL295007A (en) | 2020-01-31 | 2022-09-01 | Nanocopoeia Llc | Amorphous nilotinib microparticles and uses thereof |
| WO2021222739A1 (en) | 2020-04-30 | 2021-11-04 | Nanocopoeia, Llc | Orally disintegrating tablet comprising amorphous solid dispersion of nilotinib |
| CA3202761A1 (en) | 2020-11-25 | 2022-06-02 | Nanocopoeia, Llc | Amorphous cabozantinib particles and uses thereof |
| JP2024520798A (ja) * | 2021-06-09 | 2024-05-24 | ロンザ・ベンド・インコーポレーテッド | 非晶質固体分散体の調製のための噴霧乾燥のための混合溶媒 |
| US11980619B2 (en) | 2021-07-28 | 2024-05-14 | Nanocopoeia, Llc | Pharmaceutical compositions and crushable tablets including amorphous solid dispersions of dasatinib and uses |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4226981A (en) * | 1977-09-28 | 1980-10-07 | Shin-Etsu Chemical Co., Ltd. | Ether-ester derivatives of cellulose and their applications |
| JPS5535031A (en) * | 1978-09-04 | 1980-03-11 | Shin Etsu Chem Co Ltd | Enteric coating composition |
| JP2528706B2 (ja) | 1988-05-30 | 1996-08-28 | ゼリア新薬工業株式会社 | ジヒドロピリジン化合物の製剤組成物 |
| ES2111065T5 (es) * | 1991-04-16 | 2005-06-16 | Nippon Shinyaku Company, Limited | Procedimiento para producir una dispersion solida. |
| JP3149122B2 (ja) * | 1994-11-07 | 2001-03-26 | 信越化学工業株式会社 | 固形腸溶製剤のコーティング用基剤 |
| JP3149125B2 (ja) * | 1995-05-01 | 2001-03-26 | 信越化学工業株式会社 | 固形腸溶製剤のコーティング用基剤 |
| PT901786E (pt) * | 1997-08-11 | 2007-08-07 | Pfizer Prod Inc | Disperções farmacêuticas sólidas com biodisponibilidade melhorada |
| EP1027885B1 (de) * | 1999-02-09 | 2008-07-09 | Pfizer Products Inc. | Zusammensetzungen basischer Arzneistoffe mit verbesserter Bioverfügbarkeit |
| ES2307482T3 (es) | 1999-02-10 | 2008-12-01 | Pfizer Products Inc. | Dispersiones farmaceuticas solidas. |
| AR028253A1 (es) * | 2000-03-16 | 2003-04-30 | Pfizer Prod Inc | Inhibidores de la glucogeno fosforilasa |
| AU2002212102A1 (en) * | 2000-11-08 | 2002-05-21 | Aeromatic-Fielder Ag | A process for production of particles for pharmaceutical compositions having increased bioavailability |
| CA2450762A1 (en) * | 2001-06-22 | 2003-01-03 | Pfizer Products Inc. | Pharmaceutical compositions comprising low-solubility and/or acid-sensitive drugs and neutralized acidic polymers |
| PL372247A1 (en) | 2002-02-01 | 2005-07-11 | Pfizer Products Inc. | Method for making homogeneous spray-dried solid amorphous drug dispersions utilizing modified spray-drying apparatus |
| KR20060115350A (ko) | 2003-09-02 | 2006-11-08 | 화이자 프로덕츠 인크. | 지프라시돈의 지속 방출형 투여 형태 |
| WO2005102092A1 (ja) | 2004-04-20 | 2005-11-03 | Urban-Nawachi Co., Ltd | 靴構造の履物 |
-
2005
- 2005-05-18 EP EP05742034A patent/EP1753402B1/de not_active Expired - Lifetime
- 2005-05-18 US US11/569,433 patent/US8207232B2/en not_active Expired - Fee Related
- 2005-05-18 CA CA002568007A patent/CA2568007A1/en not_active Abandoned
- 2005-05-18 DE DE602005010074T patent/DE602005010074D1/de not_active Expired - Fee Related
- 2005-05-18 MX MXPA06013891A patent/MXPA06013891A/es not_active Application Discontinuation
- 2005-05-18 JP JP2007514203A patent/JP2008501009A/ja active Pending
- 2005-05-18 AT AT05742034T patent/ATE409462T1/de not_active IP Right Cessation
- 2005-05-18 WO PCT/IB2005/001580 patent/WO2005115330A2/en not_active Ceased
-
2012
- 2012-06-26 US US13/533,637 patent/US8940800B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA06013891A (es) | 2007-01-26 |
| EP1753402B1 (de) | 2008-10-01 |
| WO2005115330A3 (en) | 2006-07-06 |
| US20080262107A1 (en) | 2008-10-23 |
| US8207232B2 (en) | 2012-06-26 |
| US20120264833A1 (en) | 2012-10-18 |
| JP2008501009A (ja) | 2008-01-17 |
| DE602005010074D1 (de) | 2008-11-13 |
| WO2005115330A2 (en) | 2005-12-08 |
| CA2568007A1 (en) | 2005-12-08 |
| EP1753402A2 (de) | 2007-02-21 |
| US8940800B2 (en) | 2015-01-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE602005010074D1 (de) | Pharmazeutische zusammensetzungen mit verbesserter leistung enthaltend ein hpmca polymer | |
| MX2012014849A (es) | Acetato succinato de hidroxipropil metil celulosa con substitucion de acetato de y succinato intensificada. | |
| ATE444060T1 (de) | Pharmazeutische zusammensetzungen enthaltend dispersionen aus arzneistoffen und neutralen polymeren | |
| AR048331A1 (es) | Sistema de administracion de farmacos con retencion gastrica | |
| WO2008149440A1 (ja) | 速溶性及び可撓性を有するフィルム製剤 | |
| ATE361758T1 (de) | Pharmazeutische zusammensetzungen enthaltend eine feste dispersion eines im wasser schwerlöslichen arzneimittels und ein löslichkeitsteigerndes polymer | |
| NO20022998D0 (no) | Farmasöytiske preparater som tilveiebringer foröket konsentrasjon av medikament | |
| EA200301250A1 (ru) | Фармацевтические композиции, содержащие слаборастворимые и/или чувствительные к кислотам лекарственные средства и нейтрализованные кислотные полимеры | |
| ATE432919T1 (de) | Azetidinderivate, ihre herstellung und sie enthaltende pharmazeutische zusammensetzungen | |
| NO20070779L (no) | Farmasoytiske doseringsformer omfattende et lavt-loselig medikament og en polymer | |
| ATE499121T1 (de) | Viskoelastische lösungen mit natriumhyaluronat und hydroxypropylmethylcellulose, herstellung und verwendungen | |
| EP1992645A4 (de) | Neue niedermolekulare hyaluronsäure und/oder salz davon und kosmetische zubereitung, pharmazeutische zusammenstezung und lebensmittelzusammensetzung damit | |
| DE602007002295D1 (de) | Arzneimittelabgabevorrichtung | |
| DE602005026395D1 (de) | Neue zyklische harnstoffderivate, deren herstellung und pharmazeutische verwendung damit als kinase-inhibitoren | |
| BRPI0408243A (pt) | método para fabricação de partìculas de polìmeros superabsorvente de cor estável, partìculas superabsorventes de cor estável, artigo absorvente, e, fralda | |
| NO20064570L (no) | Farmasoytiske preparater | |
| DE60026357D1 (de) | An- und abschwellende polymermischungen | |
| MXPA03011935A (es) | Composiciones farmaceuticas que contienen conjuntos de polimero y farmaco. | |
| NO20025759L (no) | Formulering basert på heparin, glykosaminoglykan eller heparinoid, anvendelse av formuleringen og formuleringsbasen | |
| NO20050419L (no) | Farmasoytiske blandinger av legemidler og polymerer av halv-orden | |
| BRPI0717369A2 (pt) | Composto, medicamento, composição farmacêutica que o contém e uso do composto. | |
| DE602004014765D1 (de) | Pharmazeutische zusammensetzungen mit atorvastatin, hergestellt ohne granulation | |
| DE602004031767D1 (de) | Stabilisierte pharmazeutische feste zusammensetzungen von arzneimitteln mit geringer löslichkeit, poloxameren und stabilisierenden polymeren | |
| ATE490967T1 (de) | 18-methyl-19-nor-androst-4-en-17,17-spiroether (18-methyl-19-nor-20- spirox-4-en-3-one), sowie diese enthaltende pharmazeutische präparate | |
| CL2008003230A1 (es) | Composicion de recubrimiento de tableta que comprende polimero celulosico, plastificante, edulcorante y composicion de sabor en polvo la que comprende saborizante asociado con portador solido; fluido de recubrimiento de tableta que comprende dicha composicion; tableta farmaceutica; proceso de preparacion de dicha tableta. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |