ATE411318T1 - Immunmodulierende oxopyrazolocinnoline als cd80- inhibitoren - Google Patents
Immunmodulierende oxopyrazolocinnoline als cd80- inhibitorenInfo
- Publication number
- ATE411318T1 ATE411318T1 AT04768008T AT04768008T ATE411318T1 AT E411318 T1 ATE411318 T1 AT E411318T1 AT 04768008 T AT04768008 T AT 04768008T AT 04768008 T AT04768008 T AT 04768008T AT E411318 T1 ATE411318 T1 AT E411318T1
- Authority
- AT
- Austria
- Prior art keywords
- oxopyrazolocinnolines
- immunomodulating
- inhibitors
- cinnolin
- pyrazolo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Transplantation (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Vascular Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/GB2004/003422 WO2006016093A1 (en) | 2004-08-09 | 2004-08-09 | Immunomodulating oxopyrrazolocinnolines as cd80 inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE411318T1 true ATE411318T1 (de) | 2008-10-15 |
Family
ID=34958175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04768008T ATE411318T1 (de) | 2004-08-09 | 2004-08-09 | Immunmodulierende oxopyrazolocinnoline als cd80- inhibitoren |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7932253B2 (de) |
| EP (1) | EP1776366B1 (de) |
| JP (1) | JP4763697B2 (de) |
| CN (1) | CN1997645B (de) |
| AT (1) | ATE411318T1 (de) |
| AU (1) | AU2004322237B2 (de) |
| CA (1) | CA2576256C (de) |
| DE (1) | DE602004017231D1 (de) |
| DK (1) | DK1776366T3 (de) |
| ES (1) | ES2315695T3 (de) |
| MX (1) | MX2007001238A (de) |
| PL (1) | PL1776366T3 (de) |
| WO (1) | WO2006016093A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0408365B8 (pt) * | 2003-03-14 | 2021-05-25 | Avidex Ltd | compostos heterocíclicos de imunomodulação |
| CN1997645B (zh) | 2004-08-09 | 2012-05-23 | 麦迪金股份公司 | 免疫调节作为cd80抑制剂的氧代吡唑并噌啉类 |
| US7906645B2 (en) * | 2004-12-24 | 2011-03-15 | Astrazeneca Ab | Heterocyclic compounds as ccr2b antagonists |
| GB0603522D0 (en) * | 2006-02-22 | 2006-04-05 | Avidex Ltd | Kinase inhibition |
| KR20140110157A (ko) * | 2013-03-04 | 2014-09-17 | 삼성전자주식회사 | 시퀀스 데이터에서의 패턴 검색 방법 및 장치 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB629412A (en) | 1946-12-24 | 1949-09-20 | Geigy Ag J R | Manufacture of metallisable monoazo dyestuffs of the pyrazolone series |
| US3576637A (en) | 1967-04-20 | 1971-04-27 | Konishiroku Photo Ind | Lith-type of emulsion containing pyrozolone |
| JPS61161285A (ja) * | 1984-12-28 | 1986-07-21 | ルセル−ユクラフ | ピラゾロ〔４，３−ｃ〕シンノリン−３−オンの誘導体、それらの塩類、これらの製造法、薬剤としての使用、これらを含有する組成物及び中間体生成物 |
| US4591589A (en) * | 1985-01-16 | 1986-05-27 | Roussel Uclaf | 2-aryl pyrazolo[4,3-c]cinnolin-3-ones |
| DE3626221A1 (de) | 1986-08-02 | 1988-02-04 | Agfa Gevaert Ag | Farbfotografisches aufzeichnungsmaterial zur herstellung farbiger aufsichtsbilder |
| DE3789754T2 (de) | 1986-11-20 | 1994-12-15 | Mitsubishi Chem Ind | Die Bildung von Lipid-peroxiden hemmende Zusammenstzung und dafür geeignete Verbindungen. |
| DE3903993A1 (de) | 1989-02-10 | 1990-08-16 | Basf Ag | Diarylsubstituierte heterocyclische verbindungen, ihre herstellung und arzneimittel daraus |
| JPH07285952A (ja) * | 1994-04-08 | 1995-10-31 | Fujisawa Pharmaceut Co Ltd | 新規複素環誘導体 |
| AR006520A1 (es) * | 1996-03-20 | 1999-09-08 | Astra Pharma Prod | Derivados de 2-arilpirazolisoquinolina y cinolinona y procedimiento para su preparacion. |
| GB9713707D0 (en) | 1997-06-27 | 1997-09-03 | Merck Sharp & Dohme | Therapeutic agents |
| SE0102404D0 (sv) | 2001-07-04 | 2001-07-04 | Active Biotech Ab | Novel immunomodulating compounds |
| ATE527247T1 (de) | 2001-07-05 | 2011-10-15 | Takeda Pharmaceutical | Benzokondensierte 5gliedrige heterocyclische verbindungen, verfahren zu deren herstellung und deren verwendung |
| WO2004048378A1 (en) | 2002-11-22 | 2004-06-10 | Active Biotech Ab | Pyrazoloquinolines with immunomodulating activity |
| EP1572689B1 (de) | 2002-12-16 | 2009-03-11 | Active Biotech AB | Tetrazyklische immunmodulierende verbindungen |
| BRPI0408365B8 (pt) * | 2003-03-14 | 2021-05-25 | Avidex Ltd | compostos heterocíclicos de imunomodulação |
| GB0325644D0 (en) | 2003-11-04 | 2003-12-10 | Avidex Ltd | Immuno ihibitory pyrazolone compounds |
| GB0411770D0 (en) | 2004-05-26 | 2004-06-30 | Avidex Ltd | Immuno inhibitory heterocyclic compouds |
| CN1997645B (zh) | 2004-08-09 | 2012-05-23 | 麦迪金股份公司 | 免疫调节作为cd80抑制剂的氧代吡唑并噌啉类 |
| GB0603522D0 (en) | 2006-02-22 | 2006-04-05 | Avidex Ltd | Kinase inhibition |
-
2004
- 2004-08-09 CN CN2004800437569A patent/CN1997645B/zh not_active Expired - Lifetime
- 2004-08-09 ES ES04768008T patent/ES2315695T3/es not_active Expired - Lifetime
- 2004-08-09 AT AT04768008T patent/ATE411318T1/de active
- 2004-08-09 JP JP2007525329A patent/JP4763697B2/ja not_active Expired - Fee Related
- 2004-08-09 DK DK04768008T patent/DK1776366T3/da active
- 2004-08-09 MX MX2007001238A patent/MX2007001238A/es active IP Right Grant
- 2004-08-09 DE DE602004017231T patent/DE602004017231D1/de not_active Expired - Lifetime
- 2004-08-09 CA CA2576256A patent/CA2576256C/en not_active Expired - Lifetime
- 2004-08-09 EP EP04768008A patent/EP1776366B1/de not_active Expired - Lifetime
- 2004-08-09 PL PL04768008T patent/PL1776366T3/pl unknown
- 2004-08-09 US US11/659,035 patent/US7932253B2/en not_active Expired - Lifetime
- 2004-08-09 AU AU2004322237A patent/AU2004322237B2/en not_active Expired
- 2004-08-09 WO PCT/GB2004/003422 patent/WO2006016093A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2008509204A (ja) | 2008-03-27 |
| US20090062289A1 (en) | 2009-03-05 |
| WO2006016093A1 (en) | 2006-02-16 |
| CA2576256A1 (en) | 2006-02-16 |
| MX2007001238A (es) | 2007-04-17 |
| EP1776366B1 (de) | 2008-10-15 |
| CN1997645A (zh) | 2007-07-11 |
| DE602004017231D1 (de) | 2008-11-27 |
| ES2315695T3 (es) | 2009-04-01 |
| DK1776366T3 (da) | 2009-02-16 |
| CN1997645B (zh) | 2012-05-23 |
| US7932253B2 (en) | 2011-04-26 |
| EP1776366A1 (de) | 2007-04-25 |
| AU2004322237B2 (en) | 2011-09-22 |
| JP4763697B2 (ja) | 2011-08-31 |
| PL1776366T3 (pl) | 2009-06-30 |
| AU2004322237A1 (en) | 2006-02-16 |
| CA2576256C (en) | 2012-01-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1776366 Country of ref document: EP |
|
| EEIH | Change in the person of patent owner |