ATE412001T1 - Zwischenprodukte bei der cephalosoprinherstellung - Google Patents

Zwischenprodukte bei der cephalosoprinherstellung

Info

Publication number
ATE412001T1
ATE412001T1 AT01967326T AT01967326T ATE412001T1 AT E412001 T1 ATE412001 T1 AT E412001T1 AT 01967326 T AT01967326 T AT 01967326T AT 01967326 T AT01967326 T AT 01967326T AT E412001 T1 ATE412001 T1 AT E412001T1
Authority
AT
Austria
Prior art keywords
cephalosoprin
production
intermediate products
products
cephalosoprin production
Prior art date
Application number
AT01967326T
Other languages
English (en)
Inventor
Peter Kremminger
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Application granted granted Critical
Publication of ATE412001T1 publication Critical patent/ATE412001T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C07D501/06—Acylation of 7-aminocephalosporanic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT01967326T 2000-09-11 2001-09-10 Zwischenprodukte bei der cephalosoprinherstellung ATE412001T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0153700A AT411996B (de) 2000-09-11 2000-09-11 Verfahren zur herstellung von cefuroxim in der form seines n-butylammoniumsalzes
EP01967326A EP1319009B1 (de) 2000-09-11 2001-09-10 Zwischenprodukte bei der cephalosoprinherstellung

Publications (1)

Publication Number Publication Date
ATE412001T1 true ATE412001T1 (de) 2008-11-15

Family

ID=3688325

Family Applications (2)

Application Number Title Priority Date Filing Date
AT0153700A AT411996B (de) 2000-09-11 2000-09-11 Verfahren zur herstellung von cefuroxim in der form seines n-butylammoniumsalzes
AT01967326T ATE412001T1 (de) 2000-09-11 2001-09-10 Zwischenprodukte bei der cephalosoprinherstellung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT0153700A AT411996B (de) 2000-09-11 2000-09-11 Verfahren zur herstellung von cefuroxim in der form seines n-butylammoniumsalzes

Country Status (12)

Country Link
US (1) US6894162B2 (de)
EP (1) EP1319009B1 (de)
JP (1) JP2004508378A (de)
KR (1) KR100864405B1 (de)
CN (1) CN1200941C (de)
AT (2) AT411996B (de)
AU (1) AU2001287725A1 (de)
CA (1) CA2419258C (de)
DE (1) DE60136285D1 (de)
DK (1) DK1319009T3 (de)
TW (1) TWI282339B (de)
WO (1) WO2002020532A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN190849B (de) * 2000-07-17 2003-08-23 Ranbaxy Lab Ltd
US20040092735A1 (en) * 2002-11-08 2004-05-13 Orchid Chemicals & Pharmaceuticals Limited Process for the preparation of cefuroxime sodium
WO2004050663A2 (en) * 2002-12-05 2004-06-17 Orchid Chemicals & Pharmaceuticals Ltd An improved process for the preparation of cefuroxime sodium
US7662955B2 (en) * 2003-03-20 2010-02-16 Orchid Chemicals And Pharmaceuticals Ltd. Process for the preparation of cefoxitin
ES2334685T3 (es) * 2005-03-29 2010-03-15 Hetero Drugs Limited Procedimiento mejorado de preparacion de cefixima.
ITMI20050871A1 (it) * 2005-05-13 2006-11-14 Acs Dobfar Spa Solvato cristallino di cefuroxima acido
CN104961749B (zh) * 2015-06-15 2016-01-13 海南灵康制药有限公司 一种头孢呋辛钠的新型工业结晶方法及其制剂
CN105440052A (zh) * 2016-01-13 2016-03-30 广东立国制药有限公司 一种头孢呋辛酸的制备方法
CN106554361B (zh) * 2016-09-30 2018-10-09 华北制药河北华民药业有限责任公司 一种头孢呋辛酯口服制剂的制备方法
CN112745338B (zh) * 2020-12-30 2022-08-16 山东金城昆仑药业有限公司 消除头孢呋辛酸中内酯杂质的方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US391589A (en) * 1888-10-23 Variety wood-worker
GB1474519A (de) * 1973-05-14 1977-05-25
US4122259A (en) 1974-08-23 1978-10-24 Glaxo Laboratories Limited 7β-[2-Aryl-2-(etherified oximino)acetamido]-3-N-substituted carbamoyloxymethylceph-3-em-4-carboxylic acids
CA1094545A (en) * 1976-02-16 1981-01-27 Michael Gregson Cephalosporin antibiotics
GB1575905A (en) 1976-04-28 1980-10-01 Glaxo Lab Ltd Salt of cefuroxime
GB2018764B (en) * 1978-04-07 1982-09-02 Glaxo Group Ltd Cephalosporin compounds
DK392779A (da) 1978-09-21 1980-03-22 Glaxo Group Ltd Fremgangsmaade til fremstilling af cephalosporinforbindelser
NL191844C (nl) 1979-02-15 1996-09-03 Glaxo Group Ltd Werkwijze voor het bereiden van natriumcefuroxime.
DE2938065A1 (de) 1979-04-06 1980-10-16 Glaxo Group Ltd Verfahren zur herstellung von cephalosporinverbindungen
DK165118C (da) 1980-11-22 1993-03-01 Gema Sa Fremgangsmaade til fremstilling af oploesninger af 7-aminocephalosporansyrer
YU44680B (en) 1982-07-30 1990-12-31 Glaxo Lab Ltd Process for obtaining very pure amorphous form of cephuroxim axetile
ES522728A0 (es) 1983-05-26 1985-06-01 Gema Sa "sales de acidos amino-beta-lactamicos, para su aplicacion a la obtencion de n-acil derivados de los mismos, y procedimiento para la obtencion de dichas sales"
GB8320520D0 (en) 1983-07-29 1983-09-01 Glaxo Group Ltd Chemical process
GB8320521D0 (en) 1983-07-29 1983-09-01 Glaxo Group Ltd Chemical process
IT1214587B (it) 1986-12-23 1990-01-18 Giovanni Bonfanti Metodo per la produzione diprodotti cristallini puri.
PL151670B1 (pl) * 1987-03-19 1990-09-28 Sposób otrzymywania półsyntetycznych cefalosporyn
JP3121903B2 (ja) 1992-02-07 2001-01-09 塩野義製薬株式会社 デアセチルセファロスポラン酸のカルバモイル化方法
AT400717B (de) 1993-07-30 1996-03-25 Biochemie Gmbh Neue guanidin- und amidinsalze von 7-amino-3- hydroxymethyl-3-cephem-4-carbonsäure
WO2000053609A1 (en) 1999-03-09 2000-09-14 Ranbaxy Laboratories Limited Process for the preparation of cefuroxime
IT1313569B1 (it) 1999-07-27 2002-09-09 Antibioticos Spa Processo per la sintesi di derivati beta-lattamici.
IN190849B (de) * 2000-07-17 2003-08-23 Ranbaxy Lab Ltd

Also Published As

Publication number Publication date
CA2419258A1 (en) 2002-03-14
EP1319009B1 (de) 2008-10-22
KR100864405B1 (ko) 2008-10-20
US20030171577A1 (en) 2003-09-11
DK1319009T3 (da) 2009-02-16
EP1319009A1 (de) 2003-06-18
ATA15372000A (de) 2004-01-15
AT411996B (de) 2004-08-26
KR20030040404A (ko) 2003-05-22
HK1057542A1 (en) 2004-04-08
CN1200941C (zh) 2005-05-11
CN1454212A (zh) 2003-11-05
TWI282339B (en) 2007-06-11
JP2004508378A (ja) 2004-03-18
WO2002020532A1 (en) 2002-03-14
AU2001287725A1 (en) 2002-03-22
DE60136285D1 (de) 2008-12-04
CA2419258C (en) 2009-12-29
US6894162B2 (en) 2005-05-17

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties