ATE412898T1 - Magnetisch unterstützter bindungstest unter verwendung eines auf magnetismus reagierendes reagenzes - Google Patents

Magnetisch unterstützter bindungstest unter verwendung eines auf magnetismus reagierendes reagenzes

Info

Publication number
ATE412898T1
ATE412898T1 AT98921225T AT98921225T ATE412898T1 AT E412898 T1 ATE412898 T1 AT E412898T1 AT 98921225 T AT98921225 T AT 98921225T AT 98921225 T AT98921225 T AT 98921225T AT E412898 T1 ATE412898 T1 AT E412898T1
Authority
AT
Austria
Prior art keywords
magnetic field
reaction mixture
responsive reagent
binding test
magnetic assisted
Prior art date
Application number
AT98921225T
Other languages
English (en)
Inventor
Thomas Rohr
Tuan Elstrom
Lawrence Howard
Eric Shain
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE412898T1 publication Critical patent/ATE412898T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/806—Electrical property or magnetic property
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/70—Nanostructure
    • Y10S977/832—Nanostructure having specified property, e.g. lattice-constant, thermal expansion coefficient
    • Y10S977/838—Magnetic property of nanomaterial
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/84—Manufacture, treatment, or detection of nanostructure
    • Y10S977/89—Deposition of materials, e.g. coating, cvd, or ald
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/92—Detection of biochemical
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/932—Specified use of nanostructure for electronic or optoelectronic application
    • Y10S977/953—Detector using nanostructure
    • Y10S977/96—Of magnetic property

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Sampling And Sample Adjustment (AREA)
AT98921225T 1997-05-16 1998-05-15 Magnetisch unterstützter bindungstest unter verwendung eines auf magnetismus reagierendes reagenzes ATE412898T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/857,440 US5998224A (en) 1997-05-16 1997-05-16 Magnetically assisted binding assays utilizing a magnetically responsive reagent

Publications (1)

Publication Number Publication Date
ATE412898T1 true ATE412898T1 (de) 2008-11-15

Family

ID=25326006

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98921225T ATE412898T1 (de) 1997-05-16 1998-05-15 Magnetisch unterstützter bindungstest unter verwendung eines auf magnetismus reagierendes reagenzes

Country Status (8)

Country Link
US (1) US5998224A (de)
EP (2) EP0981749B1 (de)
JP (4) JP4237267B2 (de)
AT (1) ATE412898T1 (de)
CA (1) CA2290018C (de)
DE (1) DE69840166D1 (de)
ES (2) ES2316163T3 (de)
WO (1) WO1998052043A1 (de)

Families Citing this family (125)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19753851A1 (de) * 1997-12-04 1999-06-10 Roche Diagnostics Gmbh Vorrichtung zum kapillaren Flüssigkeitstransport
JP5122705B2 (ja) * 1999-01-25 2013-01-16 ミナーヴァ・バイオテクノロジーズ・コーポレーション 神経変性疾患における異常型タンパク質凝集の迅速かつ高感度の検出
WO2000049407A2 (de) * 1999-02-17 2000-08-24 Kilian Hennes Verfahren zum darstellen von biologisch aktivierten induktivitätsändernden partikeln sowie vorrichtung dafür
WO2001018235A2 (en) * 1999-09-09 2001-03-15 Eichrom Technologies, Inc. Lateral flow device with metal oxide indicator and assay method employing same
US7537938B2 (en) 2000-04-28 2009-05-26 Monogram Biosciences, Inc. Biomarker detection in circulating cells
US7015047B2 (en) * 2001-01-26 2006-03-21 Aviva Biosciences Corporation Microdevices having a preferential axis of magnetization and uses thereof
US7811768B2 (en) * 2001-01-26 2010-10-12 Aviva Biosciences Corporation Microdevice containing photorecognizable coding patterns and methods of using and producing the same
FR2826882B1 (fr) * 2001-07-09 2003-09-12 Bio Merieux Procede de traitement de particules magnetiques et configurations d'aimants permettant la mise en oeuvre de ce procede
US7169578B2 (en) * 2001-07-27 2007-01-30 Surface Logix, Inc. Cell isolation and screening device and method of using same
US7285412B2 (en) * 2001-07-27 2007-10-23 Surface Logix Inc. Device for magnetic immobilization of cells
US7169577B2 (en) * 2001-07-27 2007-01-30 Surface Logix, Inc. Cell isolation and screening device and method of using same
US10022078B2 (en) 2004-07-13 2018-07-17 Dexcom, Inc. Analyte sensor
WO2003072830A1 (en) * 2002-02-22 2003-09-04 Purdue Research Foundation Magnetic nanomaterials and methods for detection of biological materials
US8697029B2 (en) * 2002-04-18 2014-04-15 The Regents Of The University Of Michigan Modulated physical and chemical sensors
CA2491093A1 (en) * 2002-06-28 2004-01-08 Purdue Research Foundation Magnetic nanomaterials and methods for detection of biological materials
US7601491B2 (en) 2003-02-06 2009-10-13 Becton, Dickinson And Company Pretreatment method for extraction of nucleic acid from biological samples and kits therefor
CN1280428C (zh) * 2003-05-19 2006-10-18 清华大学 一种基于微小颗粒的生物芯片系统及其应用
FR2855613B1 (fr) * 2003-05-26 2005-08-19 Biocytex Procede de detection et de quantification multiplex d'analytes dans un echantillon a l'aide de microspheres
US7402398B2 (en) 2003-07-17 2008-07-22 Monogram Biosciences, Inc. Measuring receptor homodimerization
EP1673399B1 (de) 2003-08-11 2017-04-05 Monogram BioSciences, Inc. Nachweis und erstellung des profils eines molekularen komplexes
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
US20050282182A1 (en) * 2003-12-30 2005-12-22 Universal Bio Research Co., Ltd. Reaction vessel and reaction apparatus comprising three-dimensional particle array
JP2005315677A (ja) * 2004-04-28 2005-11-10 Canon Inc 検出装置および検出方法
DE102004033811A1 (de) * 2004-07-12 2006-02-02 Salama, Abdulgabar, Prof. Dr. Verfahren zum einfachen und schnellen Nachweis von Zellen und Biomolekülen mit Hilfe paramagnetischer Partikel
US7946984B2 (en) 2004-07-13 2011-05-24 Dexcom, Inc. Transcutaneous analyte sensor
US20060024776A1 (en) * 2004-08-02 2006-02-02 Mcmillian Ray Magnetic particle capture of whole intact organisms from clinical samples
US8133703B2 (en) 2004-10-27 2012-03-13 Ceoheid Closed-system multi-stage nucleic acid amplification reactions
US7939267B2 (en) * 2004-11-04 2011-05-10 Laboratory Corporation Of America Holdings Detection of activation of endothelial cells as surrogate marker for angiogenesis
CA2594483C (en) 2005-01-28 2014-08-26 Duke University Apparatuses and methods for manipulating droplets on a printed circuit board
EP1705486B1 (de) 2005-02-05 2008-03-19 Samsung Electronics Co., Ltd. Sensorschalter und seine Verwendung in einem Nachweisverfahren
US7781228B2 (en) * 2005-04-07 2010-08-24 Menon & Associates, Inc. Magnetic resonance system and method to detect and confirm analytes
US7300631B2 (en) 2005-05-02 2007-11-27 Bioscale, Inc. Method and apparatus for detection of analyte using a flexural plate wave device and magnetic particles
US7263874B2 (en) * 2005-06-08 2007-09-04 Bioscale, Inc. Methods and apparatus for determining properties of a fluid
US20060281104A1 (en) * 2005-06-13 2006-12-14 Macevicz Stephen C Leuco dye particles and uses thereof
US20070020699A1 (en) * 2005-07-19 2007-01-25 Idexx Laboratories, Inc. Lateral flow assay and device using magnetic particles
US20070059782A1 (en) * 2005-09-13 2007-03-15 Graham Henry A Magnetic particle tagged blood bank reagents and techniques
US9488665B2 (en) * 2005-09-13 2016-11-08 Chrome Red Technologies, Llc Magnetic particle tagged reagents and techniques
US20070166730A1 (en) 2006-01-19 2007-07-19 Menon & Associates, Inc. Magnetic resonance system and method to detect and confirm analytes
US20100239864A1 (en) * 2006-03-27 2010-09-23 Tokyo Institute Of Technology Method of manufacturing polymer coated ferromagnetic particles and polymer coated ferromagnetic particles
US8492168B2 (en) * 2006-04-18 2013-07-23 Advanced Liquid Logic Inc. Droplet-based affinity assays
US20140193807A1 (en) 2006-04-18 2014-07-10 Advanced Liquid Logic, Inc. Bead manipulation techniques
US9476856B2 (en) * 2006-04-13 2016-10-25 Advanced Liquid Logic, Inc. Droplet-based affinity assays
US7727723B2 (en) * 2006-04-18 2010-06-01 Advanced Liquid Logic, Inc. Droplet-based pyrosequencing
US7901947B2 (en) 2006-04-18 2011-03-08 Advanced Liquid Logic, Inc. Droplet-based particle sorting
US8637324B2 (en) 2006-04-18 2014-01-28 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
US10078078B2 (en) 2006-04-18 2018-09-18 Advanced Liquid Logic, Inc. Bead incubation and washing on a droplet actuator
US8809068B2 (en) 2006-04-18 2014-08-19 Advanced Liquid Logic, Inc. Manipulation of beads in droplets and methods for manipulating droplets
US7439014B2 (en) 2006-04-18 2008-10-21 Advanced Liquid Logic, Inc. Droplet-based surface modification and washing
US8900828B2 (en) 2006-05-01 2014-12-02 Cepheid Methods and apparatus for sequential amplification reactions
WO2009111769A2 (en) 2008-03-07 2009-09-11 Advanced Liquid Logic, Inc. Reagent and sample preparation and loading on a fluidic device
US8119352B2 (en) * 2006-06-20 2012-02-21 Cepheld Multi-stage amplification reactions by control of sequence replication times
JP5277165B2 (ja) * 2006-07-24 2013-08-28 ベクトン・ディキンソン・アンド・カンパニー 分析粒子凝集およびイメージング装置および方法
EP2570811B1 (de) 2007-02-09 2014-11-26 Advanced Liquid Logic, Inc. Tröpfchenaktuatorvorrichtungen und Verfahren mit magnetischen Beads
US9068977B2 (en) * 2007-03-09 2015-06-30 The Regents Of The University Of Michigan Non-linear rotation rates of remotely driven particles and uses thereof
WO2011084703A2 (en) 2009-12-21 2011-07-14 Advanced Liquid Logic, Inc. Enzyme assays on a droplet actuator
WO2009032863A2 (en) 2007-09-04 2009-03-12 Advanced Liquid Logic, Inc. Droplet actuator with improved top substrate
AU2008345138B2 (en) 2007-12-23 2014-05-29 Advanced Liquid Logic, Inc. Droplet actuator configurations and methods of conducting droplet operations
US7927561B2 (en) * 2008-01-10 2011-04-19 Becton, Dickinson And Company Rapid particle detection assay
JP5466651B2 (ja) 2008-01-17 2014-04-09 ザ リージェンツ オブ ザ ユニヴァーシティー オブ カリフォルニア 集積化された磁場生成および検出プラットフォーム
US8076162B2 (en) * 2008-04-07 2011-12-13 Life Bioscience, Inc. Method of providing particles having biological-binding areas for biological applications
US8852952B2 (en) 2008-05-03 2014-10-07 Advanced Liquid Logic, Inc. Method of loading a droplet actuator
US8926065B2 (en) 2009-08-14 2015-01-06 Advanced Liquid Logic, Inc. Droplet actuator devices and methods
US9091649B2 (en) 2009-11-06 2015-07-28 Advanced Liquid Logic, Inc. Integrated droplet actuator for gel; electrophoresis and molecular analysis
WO2011100358A2 (en) * 2010-02-09 2011-08-18 Fabrico Technology, Inc. Systems and methods for detecting target analytes
WO2012019104A1 (en) 2010-08-05 2012-02-09 Abbott Point Of Care Inc. Immunoassay method and device with magnetically susceptible bead capture
EP2601526B1 (de) 2010-08-05 2016-12-21 Abbott Point Of Care, Inc. Magnetischer immunsensor und anwendungsverfahren dafür
US9329175B2 (en) 2010-08-05 2016-05-03 Abbott Point Of Care Inc. Oscillating immunoassay method and device
US11402375B2 (en) 2010-08-05 2022-08-02 Abbott Point Of Care Inc. Magnetic immunosensor with trench configuration and method of use
US8846331B2 (en) 2010-08-27 2014-09-30 The Regents Of The University Of Michigan Asynchronous magnetic bead rotation sensing systems and methods
US20120077184A1 (en) * 2010-09-28 2012-03-29 Starkdx Incorporated Electromagnetic multiplex assay biosensor
WO2012142179A2 (en) 2011-04-11 2012-10-18 The Regents Of The University Of Michigan Magnetically induced microspinning for super-detection and super-characterization of biomarkers and live cells
EP2707131B1 (de) 2011-05-09 2019-04-24 Advanced Liquid Logic, Inc. Mikrofluidische rückkopplung mittels impedanzerkennung
JP5894272B2 (ja) 2011-07-06 2016-03-23 アドバンスト リキッド ロジック インコーポレイテッドＡｄｖａｎｃｅｄ Ｌｉｑｕｉｄ Ｌｏｇｉｃ， Ｉｎｃ． 液滴アクチュエーターにおける試薬保存
WO2013009927A2 (en) 2011-07-11 2013-01-17 Advanced Liquid Logic, Inc. Droplet actuators and techniques for droplet-based assays
WO2013016413A2 (en) 2011-07-25 2013-01-31 Advanced Liquid Logic Inc Droplet actuator apparatus and system
JP2013088164A (ja) * 2011-10-14 2013-05-13 Hitachi High-Technologies Corp 自動分析装置
WO2013078216A1 (en) 2011-11-21 2013-05-30 Advanced Liquid Logic Inc Glucose-6-phosphate dehydrogenase assays
US9797817B2 (en) 2012-05-03 2017-10-24 The Regents Of The University Of Michigan Multi-mode separation for target detection
EP2664914A1 (de) * 2012-05-16 2013-11-20 Koninklijke Philips N.V. Magnetisch unterstützte Verarbeitung eines Mediums
EP2867645B1 (de) 2012-06-27 2019-06-05 Advanced Liquid Logic, Inc. Verfahren und tropfenaktuatorkonzepte zur reduzierung einer bläschenbildung
JP6217936B2 (ja) * 2012-07-06 2017-10-25 凸版印刷株式会社 被検物質の検出システム
JP6120518B2 (ja) * 2012-10-10 2017-04-26 公益財団法人かずさＤｎａ研究所 簡易測定器具
US20160296945A1 (en) 2013-03-15 2016-10-13 Ancera, Inc. Systems and methods for active particle separation
WO2014144340A1 (en) 2013-03-15 2014-09-18 Ancera, Inc. Systems and methods for three-dimensional extraction of target particles ferrofluids
US20160299132A1 (en) 2013-03-15 2016-10-13 Ancera, Inc. Systems and methods for bead-based assays in ferrofluids
JP6420055B2 (ja) * 2013-03-29 2018-11-07 積水メディカル株式会社 イムノクロマト用着色粒子及びこれを用いた診断用イムノクロマト試薬
US9983110B2 (en) 2013-11-04 2018-05-29 The Regents Of The University Of Michigan Asynchronous magnetic bead rotation (AMBR) microviscometer for analysis of analytes
EP2883961B8 (de) * 2013-12-12 2017-09-27 Altratech Limited Nukleinsäureanalyseverfahren und -vorrichtung
JP6241537B2 (ja) * 2014-03-14 2017-12-06 株式会社島津製作所 磁性体粒子の操作方法および磁性体粒子操作用デバイス
JP6574207B2 (ja) 2014-05-05 2019-09-11 スリーディー グラス ソリューションズ，インク３Ｄ Ｇｌａｓｓ Ｓｏｌｕｔｉｏｎｓ，Ｉｎｃ 光活性基板を製造する、２ｄ及び３ｄインダクタ、アンテナ、並びにトランス
WO2015177933A1 (ja) * 2014-05-23 2015-11-26 株式会社島津製作所 磁性体粒子の操作方法および磁性体粒子操作用デバイス
WO2016013115A1 (ja) * 2014-07-25 2016-01-28 株式会社 リージャー 希釈生体試料成分の分析方法
KR101860543B1 (ko) * 2015-01-09 2018-05-24 한양대학교 에리카산학협력단 성호르몬 검출용 시약 키트 및 이를 이용한 성호르몬 검출 방법
US11285490B2 (en) 2015-06-26 2022-03-29 Ancera, Llc Background defocusing and clearing in ferrofluid-based capture assays
JP6865466B2 (ja) * 2015-06-26 2021-04-28 株式会社カワノラボ 分散質分析方法、および分析装置
WO2017052506A1 (en) * 2015-09-22 2017-03-30 Halliburton Energy Services, Inc. Optical device window cleaning system
US10070533B2 (en) 2015-09-30 2018-09-04 3D Glass Solutions, Inc. Photo-definable glass with integrated electronics and ground plane
AU2017223993B2 (en) 2016-02-25 2019-07-04 3D Glass Solutions, Inc. 3D capacitor and capacitor array fabricating photoactive substrates
US12165809B2 (en) 2016-02-25 2024-12-10 3D Glass Solutions, Inc. 3D capacitor and capacitor array fabricating photoactive substrates
WO2017177171A1 (en) 2016-04-08 2017-10-12 3D Glass Solutions, Inc. Methods of fabricating photosensitive substrates suitable for optical coupler
KR101994370B1 (ko) * 2016-08-24 2019-06-28 주식회사 제놉시 항체 및 자성 나노 입자가 결합된 전도성 고분자를 포함하는 혈중 암세포 검출 및 회수용 자성 나노 구조체
US10845449B2 (en) 2016-10-20 2020-11-24 Quantum Diamond Technologies Inc. Methods and apparatus for magnetic particle analysis using diamond magnetic imaging
US10590409B2 (en) 2016-12-06 2020-03-17 Wisconsin Alumni Research Foundation Method and device for disaggregation via heterogeneous particles
US11513115B2 (en) 2016-12-23 2022-11-29 Quantum Diamond Technologies Inc. Methods and apparatus for magnetic multi-bead assays
US11101532B2 (en) 2017-04-28 2021-08-24 3D Glass Solutions, Inc. RF circulator
KR102418671B1 (ko) 2017-07-07 2022-07-12 3디 글래스 솔루션즈 인코포레이티드 패키지 광활성 유리 기판들에서 ｒｆ 시스템을 위한 2ｄ 및 3ｄ 집중 소자 디바이스들
ES2932362T3 (es) 2017-07-31 2023-01-18 Quantum Diamond Tech Inc Sistema sensor que comprende un cartucho de muestras que incluye una membrana flexible para soportar una muestra
KR102614826B1 (ko) 2017-12-15 2023-12-19 3디 글래스 솔루션즈 인코포레이티드 결합 전송 라인 공진 rf 필터
KR102600200B1 (ko) 2018-01-04 2023-11-10 3디 글래스 솔루션즈 인코포레이티드 고효율 ｒｆ 회로들을 위한 임피던스 정합 도전성 구조
JP7272348B2 (ja) * 2018-03-20 2023-05-12 住友電気工業株式会社 微小粒子計測装置
US11076489B2 (en) 2018-04-10 2021-07-27 3D Glass Solutions, Inc. RF integrated power condition capacitor
US10903545B2 (en) 2018-05-29 2021-01-26 3D Glass Solutions, Inc. Method of making a mechanically stabilized radio frequency transmission line device
WO2019235270A1 (ja) * 2018-06-08 2019-12-12 国立研究開発法人産業技術総合研究所 標的物質検出方法及び標的物質検出キット
US11139582B2 (en) 2018-09-17 2021-10-05 3D Glass Solutions, Inc. High efficiency compact slotted antenna with a ground plane
KR102493538B1 (ko) 2018-12-28 2023-02-06 3디 글래스 솔루션즈 인코포레이티드 광활성 유리 기판들에서 ｒｆ, 마이크로파, 및 ｍｍ 파 시스템들을 위한 이종 통합
US11270843B2 (en) 2018-12-28 2022-03-08 3D Glass Solutions, Inc. Annular capacitor RF, microwave and MM wave systems
KR20210147040A (ko) 2019-04-05 2021-12-06 3디 글래스 솔루션즈 인코포레이티드 유리 기반의 빈 기판 집적 도파관 디바이스
KR102601781B1 (ko) 2019-04-18 2023-11-14 3디 글래스 솔루션즈 인코포레이티드 고효율 다이 다이싱 및 릴리스
JP7051004B2 (ja) * 2019-05-09 2022-04-08 三菱電機株式会社 磁性摩耗粉量測定装置及び機械装置
CA3177603C (en) 2020-04-17 2024-01-09 3D Glass Solutions, Inc. Broadband induction
WO2021230821A1 (en) * 2020-05-12 2021-11-18 National University Of Singapore A method for virus and biomarker detection
RU200521U1 (ru) * 2020-05-26 2020-10-28 Алексей Николаевич Темников Портативный сканер-дисплей магнитного поля
US12690457B2 (en) 2021-07-15 2026-07-21 3D Glass Solutions, Inc. Thermal transfer, management and integrated control structure
EP4252907A1 (de) * 2022-03-30 2023-10-04 Blink AG Verfahren zur anordnung von mikrokugeln in einer nichtwässrigen flüssigen phase

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985649A (en) * 1974-11-25 1976-10-12 Eddelman Roy T Ferromagnetic separation process and material
US4070246A (en) * 1976-04-09 1978-01-24 Abbott Laboratories Reactive matrices
GB8401368D0 (en) * 1984-01-19 1984-02-22 Amersham Int Plc Assay method
US5076950A (en) * 1985-12-20 1991-12-31 Syntex (U.S.A.) Inc. Magnetic composition for particle separation
JPH0614051B2 (ja) * 1986-02-10 1994-02-23 株式会社ニッテク 抗原―抗体不溶化担体の選別方法
US4960691A (en) * 1986-09-29 1990-10-02 Abbott Laboratories Chromatographic test strip for determining ligands or receptors
JPS63108264A (ja) * 1986-10-25 1988-05-13 Nippon Telegr & Teleph Corp <Ntt> 磁気免疫測定方法および該方法を実施するために使用する検査試薬片
US5236824A (en) * 1988-04-26 1993-08-17 Nippon Telegraph And Telephone Corporation Laser magnetic immunoassay method and method by a magnetophoresis apparatus therefor
JP2599175B2 (ja) * 1988-04-26 1997-04-09 日本電信電話株式会社 レーザ磁気免疫測定方法及び測定装置並びにレーザ磁気免疫測定に用いる超常磁性体標識体及びその製造方法
US5145784A (en) * 1988-05-04 1992-09-08 Cambridge Biotech Corporation Double capture assay method employing a capillary flow device
US5108933A (en) * 1988-09-16 1992-04-28 Immunicon Corporation Manipulation of colloids for facilitating magnetic separations
US5252459A (en) * 1988-09-23 1993-10-12 Abbott Laboratories Indicator reagents, diagnostic assays and test kits employing organic polymer latex particles
CA1335181C (en) * 1988-10-11 1995-04-11 R. Alan Hardwick System for selective cell separation from cell concentrate
TW221493B (de) * 1990-07-10 1994-03-01 Cardiovascular Diagnostics Inc
JPH0552849A (ja) * 1991-08-28 1993-03-02 Terumo Corp 検体の特異的検出および特異的分離方法
EP0631668B1 (de) * 1992-03-20 2002-09-04 Abbott Laboratories Bestimmung von bindungsaffinität mittels magnetisch markierter bindungspartner
US5445971A (en) * 1992-03-20 1995-08-29 Abbott Laboratories Magnetically assisted binding assays using magnetically labeled binding members
US5445970A (en) * 1992-03-20 1995-08-29 Abbott Laboratories Magnetically assisted binding assays using magnetically labeled binding members
JP2625577B2 (ja) * 1992-03-20 1997-07-02 アボツト・ラボラトリーズ 磁気標識した結合要素を用いた磁気制御型結合アッセイ
ATE140880T1 (de) * 1992-05-01 1996-08-15 Univ Pennsylvania Fluessigkeitsbehandlung in mikrofabrizierten analytischen vorrichtungen
US5322756A (en) * 1992-07-09 1994-06-21 Xerox Corporation Magnetic fluids and method of preparation
US5358659A (en) * 1992-07-09 1994-10-25 Xerox Corporation Magnetic materials with single-domain and multidomain crystallites and a method of preparation
WO1994020855A1 (en) * 1993-03-04 1994-09-15 Sapidyne, Inc. Assay flow apparatus and method
US5374531A (en) * 1993-03-22 1994-12-20 Zynaxis, Inc. Immunoassay for determination of cells
FR2708348B1 (fr) * 1993-07-28 1995-10-06 Stago Diagnostica Procédé de dosage d'une substance immunologique au moyen de particules de latex magnétiques et de particules non-magnétiques.
GB9409333D0 (en) 1994-05-10 1994-06-29 Palmer Richard F Analytical method and device for use therein
US5656429A (en) * 1994-10-03 1997-08-12 Adelman; Lonnie W. Polynucleotide and protein analysis method using magnetizable moieties
FR2732116B1 (fr) * 1995-03-21 1997-05-09 Bio Merieux Procede et dispositif pour la determination qualitative et/ou quantitative d'un analyte, notamment d'une bacterie, dans un echantillon, par voie magnetique
JPH08304399A (ja) * 1995-04-28 1996-11-22 Mitsubishi Chem Corp 磁性体粒子の分離方法およびそれを用いた免疫分析方法

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JP4806457B2 (ja) 2011-11-02
ES2378782T3 (es) 2012-04-17
JP2011257413A (ja) 2011-12-22
JP2002504993A (ja) 2002-02-12
WO1998052043A1 (en) 1998-11-19
EP1881325A1 (de) 2008-01-23
JP4324212B2 (ja) 2009-09-02
EP1881325B1 (de) 2012-01-11
CA2290018A1 (en) 1998-11-19
JP4237267B2 (ja) 2009-03-11
EP0981749A1 (de) 2000-03-01
JP2008003083A (ja) 2008-01-10
JP2009204617A (ja) 2009-09-10
CA2290018C (en) 2011-07-19
DE69840166D1 (de) 2008-12-11

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