ATE414707T1 - Verfahren zur herstellung von 4-amino-4'-demethyl-4-desoxypodophylotoxin - Google Patents

Verfahren zur herstellung von 4-amino-4'-demethyl-4-desoxypodophylotoxin

Info

Publication number: ATE414707T1
Authority: AT; Austria
Prior art keywords: demethyl; amino; desoxypodophyllotoxin; desoxypodophylotoxin; producing
Prior art date: 2005-07-19

Application number

AT06764221T

Other languages

English (en)

Inventor

Yves Guminski

Martial Grousseaud

Thierry Imbert

Original Assignee

Pf Medicament

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-07-19

Filing date

2006-07-19

Publication date

2008-12-15

2006-07-19 Application filed by Pf Medicament filed Critical Pf Medicament

2008-12-15 Application granted granted Critical

2008-12-15 Publication of ATE414707T1 publication Critical patent/ATE414707T1/de

Links

238000004519 manufacturing process Methods 0.000 title 1
239000002253 acid Substances 0.000 abstract 2
UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 abstract 2
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
239000003960 organic solvent Substances 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
230000002194 synthesizing effect Effects 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Telephone Set Structure (AREA)

AT06764221T 2005-07-19 2006-07-19 Verfahren zur herstellung von 4-amino-4'-demethyl-4-desoxypodophylotoxin ATE414707T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR0507642A FR2888849B1 (fr)	2005-07-19	2005-07-19	Procede de preparation de la 4b-amino-4'-demethyl-4-desoxypodophyllotoxine

Publications (1)

Publication Number	Publication Date
ATE414707T1 true ATE414707T1 (de)	2008-12-15

Family

ID=36035759

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT06764221T ATE414707T1 (de)	2005-07-19	2006-07-19	Verfahren zur herstellung von 4-amino-4'-demethyl-4-desoxypodophylotoxin

Country Status (29)

Country	Link
US (2)	US7932406B2 (de)
EP (1)	EP1907396B1 (de)
JP (1)	JP5140583B2 (de)
KR (1)	KR101357664B1 (de)
CN (1)	CN101223176B (de)
AT (1)	ATE414707T1 (de)
AU (1)	AU2006271645B2 (de)
BR (1)	BRPI0613418A2 (de)
CA (1)	CA2616064C (de)
CY (1)	CY1108804T1 (de)
DE (1)	DE602006003769D1 (de)
DK (1)	DK1907396T3 (de)
ES (1)	ES2317561T3 (de)
FR (1)	FR2888849B1 (de)
HR (1)	HRP20090103T3 (de)
IL (1)	IL188716A0 (de)
MA (1)	MA29690B1 (de)
MX (1)	MX2008000961A (de)
NO (1)	NO20080812L (de)
NZ (1)	NZ565923A (de)
PL (1)	PL1907396T3 (de)
PT (1)	PT1907396E (de)
RS (1)	RS50782B (de)
RU (1)	RU2405787C2 (de)
SI (1)	SI1907396T1 (de)
TN (1)	TNSN08030A1 (de)
UA (1)	UA90530C2 (de)
WO (1)	WO2007010007A1 (de)
ZA (1)	ZA200801577B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2637886A (en) *	1950-04-06	1953-05-12	Walther Trautwein	Slide fastener
FR2888849B1 (fr) *	2005-07-19	2007-10-05	Pierre Fabre Medicament Sa	Procede de preparation de la 4b-amino-4'-demethyl-4-desoxypodophyllotoxine
FR2921368B1 (fr) *	2007-09-25	2012-10-12	Pf Medicament	Nouveau procede de synthese de derives anticancereux de (poly) aminoalkylaminoacetamide d'epipodophyllotoxine.
FR2935143B1 (fr) *	2008-08-19	2010-12-03	Pf Medicament	Nouveaus derives (poly)aminoalkylaminoalkylamides, alkyl-urees, ou alkyl-sulfonamides d'epipodophyllotoxine, leur procede de preparation et leur application en therapeuthique comme agent cancereux
JP5749260B2 (ja) *	2009-06-29	2015-07-15	メルツ・ファルマ・ゲーエムベーハー・ウント・コ・カーゲーアーアー	ネラメキサンの製造方法
HRP20130485T1 (en) *	2009-06-29	2013-06-30	Merz Pharma Gmbh & Co. Kgaa	Method of preparing 1-amino-1,3,3,5,5-pentamethylcyclohexane
EP2448911A1 (de)	2009-06-29	2012-05-09	Merz Pharma GmbH & Co. KGaA	Verfahren zur herstellung von 1-chloracetamid-1,3,3,5,5-pentamethylcyclohexan
CN110294764B (zh) *	2019-07-15	2021-04-20	中国科学院兰州化学物理研究所	一种偶氮键连接的鬼臼毒素衍生物及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS61126095A (ja) *	1984-11-26	1986-06-13	Fuji Yakuhin Kogyo Kk	新規グルコサミン誘導体
JPS62215583A (ja) *	1986-03-14	1987-09-22	Takeda Chem Ind Ltd	ピラゾリジノン誘導体およびその製造法
US5332811A (en) *	1989-09-12	1994-07-26	The University Of North Carolina At Chapel Hill	Etopside analogs
PL204924B1 (pl) *	1999-10-06	2010-02-26	Tibotec Pharm Ltd	Heksahydrofuro [2,3-b] furanylo-3-N-{3(1,3-benzodioksolilo-5-sulfonylo) (izobutylo) amino] -1-benzylo-2-hydroksypropylo} karbaminian oraz jego zastosowanie
EP1599485A2 (de)	2003-02-18	2005-11-30	Ranbaxy Laboratories, Ltd.	Podophyllotoxinderivative als antitumormittel
FR2869035B1 (fr) *	2004-04-16	2006-07-14	Pierre Fabre Medicament Sa	Derives (poly)aminoalkylaminoacetamide d'epipodophyllotoxine leur procede de preparation et leurs applications en therapeutique comme agent anticancereux
FR2888849B1 (fr) *	2005-07-19	2007-10-05	Pierre Fabre Medicament Sa	Procede de preparation de la 4b-amino-4'-demethyl-4-desoxypodophyllotoxine

2005
- 2005-07-19 FR FR0507642A patent/FR2888849B1/fr not_active Expired - Fee Related
2006
- 2006-07-19 US US11/988,942 patent/US7932406B2/en not_active Expired - Fee Related
- 2006-07-19 PT PT06764221T patent/PT1907396E/pt unknown
- 2006-07-19 HR HR20090103T patent/HRP20090103T3/xx unknown
- 2006-07-19 AU AU2006271645A patent/AU2006271645B2/en not_active Ceased
- 2006-07-19 BR BRPI0613418-1A patent/BRPI0613418A2/pt not_active IP Right Cessation
- 2006-07-19 WO PCT/EP2006/064420 patent/WO2007010007A1/fr not_active Ceased
- 2006-07-19 MX MX2008000961A patent/MX2008000961A/es active IP Right Grant
- 2006-07-19 RS RSP-2009/0079A patent/RS50782B/sr unknown
- 2006-07-19 UA UAA200801997A patent/UA90530C2/uk unknown
- 2006-07-19 EP EP06764221A patent/EP1907396B1/de active Active
- 2006-07-19 AT AT06764221T patent/ATE414707T1/de active
- 2006-07-19 RU RU2008106100/04A patent/RU2405787C2/ru not_active IP Right Cessation
- 2006-07-19 SI SI200630166T patent/SI1907396T1/sl unknown
- 2006-07-19 NZ NZ565923A patent/NZ565923A/en not_active IP Right Cessation
- 2006-07-19 CN CN2006800262703A patent/CN101223176B/zh not_active Expired - Fee Related
- 2006-07-19 DE DE602006003769T patent/DE602006003769D1/de active Active
- 2006-07-19 ES ES06764221T patent/ES2317561T3/es active Active
- 2006-07-19 DK DK06764221T patent/DK1907396T3/da active
- 2006-07-19 PL PL06764221T patent/PL1907396T3/pl unknown
- 2006-07-19 CA CA2616064A patent/CA2616064C/fr not_active Expired - Fee Related
- 2006-07-19 JP JP2008521967A patent/JP5140583B2/ja not_active Expired - Fee Related
- 2006-07-19 KR KR1020087002443A patent/KR101357664B1/ko not_active Expired - Fee Related
2008
- 2008-01-10 IL IL188716A patent/IL188716A0/en unknown
- 2008-01-18 TN TNP2008000030A patent/TNSN08030A1/fr unknown
- 2008-02-01 MA MA30614A patent/MA29690B1/fr unknown
- 2008-02-14 NO NO20080812A patent/NO20080812L/no not_active Application Discontinuation
- 2008-02-18 ZA ZA200801577A patent/ZA200801577B/xx unknown
2009
- 2009-02-18 CY CY20091100177T patent/CY1108804T1/el unknown
2010
- 2010-09-30 US US12/894,684 patent/US8193379B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
RU2405787C2 (ru)	2010-12-10
SI1907396T1 (sl)	2009-04-30
HRP20090103T3 (hr)	2009-03-31
EP1907396B1 (de)	2008-11-19
NZ565923A (en)	2010-01-29
TNSN08030A1 (fr)	2009-07-14
FR2888849A1 (fr)	2007-01-26
CN101223176A (zh)	2008-07-16
WO2007010007A1 (fr)	2007-01-25
PT1907396E (pt)	2009-02-13
ES2317561T3 (es)	2009-04-16
IL188716A0 (en)	2008-08-07
CY1108804T1 (el)	2014-04-09
NO20080812L (no)	2008-02-14
JP2009501764A (ja)	2009-01-22
US20110021791A1 (en)	2011-01-27
JP5140583B2 (ja)	2013-02-06
BRPI0613418A2 (pt)	2011-01-11
AU2006271645A1 (en)	2007-01-25
ZA200801577B (en)	2009-01-28
MX2008000961A (es)	2008-03-27
US8193379B2 (en)	2012-06-05
EP1907396A1 (de)	2008-04-09
RU2008106100A (ru)	2009-08-27
UA90530C2 (uk)	2010-05-11
CA2616064C (fr)	2013-11-05
KR101357664B1 (ko)	2014-02-03
KR20080036058A (ko)	2008-04-24
HK1114101A1 (en)	2008-10-24
CA2616064A1 (fr)	2007-01-25
MA29690B1 (fr)	2008-08-01
RS50782B (sr)	2010-08-31
US20090137826A1 (en)	2009-05-28
PL1907396T3 (pl)	2009-04-30
DK1907396T3 (da)	2009-03-02
FR2888849B1 (fr)	2007-10-05
CN101223176B (zh)	2011-06-15
US7932406B2 (en)	2011-04-26
AU2006271645B2 (en)	2012-02-02
DE602006003769D1 (de)	2009-01-02

Legal Events

Date

Code

Title

Description

2009-07-15

UEP

Publication of translation of european patent specification

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