DK1907396T3 - Fremgangsmåde til fremstilling af 4-beta-amino-4'-demethyl-4-deoxypodophyllotoxin - Google Patents
Fremgangsmåde til fremstilling af 4-beta-amino-4'-demethyl-4-deoxypodophyllotoxinInfo
- Publication number
- DK1907396T3 DK1907396T3 DK06764221T DK06764221T DK1907396T3 DK 1907396 T3 DK1907396 T3 DK 1907396T3 DK 06764221 T DK06764221 T DK 06764221T DK 06764221 T DK06764221 T DK 06764221T DK 1907396 T3 DK1907396 T3 DK 1907396T3
- Authority
- DK
- Denmark
- Prior art keywords
- demethyl
- amino
- desoxypodophyllotoxin
- deoxypodophyllotoxin
- beta
- Prior art date
Links
- 239000002253 acid Substances 0.000 abstract 2
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 abstract 2
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Telephone Set Structure (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0507642A FR2888849B1 (fr) | 2005-07-19 | 2005-07-19 | Procede de preparation de la 4b-amino-4'-demethyl-4-desoxypodophyllotoxine |
| PCT/EP2006/064420 WO2007010007A1 (fr) | 2005-07-19 | 2006-07-19 | PROCEDE DE PREPARATION DE LA 4β-AMINO-4'-DEMETHYL-4-DESOXYPODOPHYLLOTOXINE |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1907396T3 true DK1907396T3 (da) | 2009-03-02 |
Family
ID=36035759
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06764221T DK1907396T3 (da) | 2005-07-19 | 2006-07-19 | Fremgangsmåde til fremstilling af 4-beta-amino-4'-demethyl-4-deoxypodophyllotoxin |
Country Status (29)
| Country | Link |
|---|---|
| US (2) | US7932406B2 (da) |
| EP (1) | EP1907396B1 (da) |
| JP (1) | JP5140583B2 (da) |
| KR (1) | KR101357664B1 (da) |
| CN (1) | CN101223176B (da) |
| AT (1) | ATE414707T1 (da) |
| AU (1) | AU2006271645B2 (da) |
| BR (1) | BRPI0613418A2 (da) |
| CA (1) | CA2616064C (da) |
| CY (1) | CY1108804T1 (da) |
| DE (1) | DE602006003769D1 (da) |
| DK (1) | DK1907396T3 (da) |
| ES (1) | ES2317561T3 (da) |
| FR (1) | FR2888849B1 (da) |
| HR (1) | HRP20090103T3 (da) |
| IL (1) | IL188716A0 (da) |
| MA (1) | MA29690B1 (da) |
| MX (1) | MX2008000961A (da) |
| NO (1) | NO20080812L (da) |
| NZ (1) | NZ565923A (da) |
| PL (1) | PL1907396T3 (da) |
| PT (1) | PT1907396E (da) |
| RS (1) | RS50782B (da) |
| RU (1) | RU2405787C2 (da) |
| SI (1) | SI1907396T1 (da) |
| TN (1) | TNSN08030A1 (da) |
| UA (1) | UA90530C2 (da) |
| WO (1) | WO2007010007A1 (da) |
| ZA (1) | ZA200801577B (da) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2637886A (en) * | 1950-04-06 | 1953-05-12 | Walther Trautwein | Slide fastener |
| FR2888849B1 (fr) * | 2005-07-19 | 2007-10-05 | Pierre Fabre Medicament Sa | Procede de preparation de la 4b-amino-4'-demethyl-4-desoxypodophyllotoxine |
| FR2921368B1 (fr) * | 2007-09-25 | 2012-10-12 | Pf Medicament | Nouveau procede de synthese de derives anticancereux de (poly) aminoalkylaminoacetamide d'epipodophyllotoxine. |
| FR2935143B1 (fr) | 2008-08-19 | 2010-12-03 | Pf Medicament | Nouveaus derives (poly)aminoalkylaminoalkylamides, alkyl-urees, ou alkyl-sulfonamides d'epipodophyllotoxine, leur procede de preparation et leur application en therapeuthique comme agent cancereux |
| CA2765743A1 (en) | 2009-06-29 | 2011-01-06 | Merz Pharma Gmbh & Co. Kgaa | Method of preparing 1-chloroacetamido-1,3,3,5,5-pentamethylcyclohexane |
| EP2448908B1 (en) * | 2009-06-29 | 2013-09-18 | Merz Pharma GmbH & Co. KGaA | Method of preparing neramexane |
| CA2765611A1 (en) * | 2009-06-29 | 2011-01-06 | Merz Pharma Gmbh & Co. Kgaa | Method of preparing 1-amino-1,3,3,5,5-pentamethylcyclohexane |
| CN110294764B (zh) * | 2019-07-15 | 2021-04-20 | 中国科学院兰州化学物理研究所 | 一种偶氮键连接的鬼臼毒素衍生物及其制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61126095A (ja) * | 1984-11-26 | 1986-06-13 | Fuji Yakuhin Kogyo Kk | 新規グルコサミン誘導体 |
| JPS62215583A (ja) * | 1986-03-14 | 1987-09-22 | Takeda Chem Ind Ltd | ピラゾリジノン誘導体およびその製造法 |
| US5332811A (en) * | 1989-09-12 | 1994-07-26 | The University Of North Carolina At Chapel Hill | Etopside analogs |
| EP1222192B8 (en) * | 1999-10-06 | 2008-10-01 | Tibotec Pharmaceuticals Ltd. | Hexahydrofuro¬2,3-b furan-3-yl-n- 3-¬(1,3-benzodioxol-5-ylsulfonyl)(isobutyl)amino -1-benzyl-2-hydroxypropyl carbamate as retroviral protease inhibitor |
| US20070066837A1 (en) * | 2003-02-18 | 2007-03-22 | Ahmed Kamal | Podophyllotoxin derivatives as antitumor agents |
| FR2869035B1 (fr) * | 2004-04-16 | 2006-07-14 | Pierre Fabre Medicament Sa | Derives (poly)aminoalkylaminoacetamide d'epipodophyllotoxine leur procede de preparation et leurs applications en therapeutique comme agent anticancereux |
| FR2888849B1 (fr) * | 2005-07-19 | 2007-10-05 | Pierre Fabre Medicament Sa | Procede de preparation de la 4b-amino-4'-demethyl-4-desoxypodophyllotoxine |
-
2005
- 2005-07-19 FR FR0507642A patent/FR2888849B1/fr not_active Expired - Fee Related
-
2006
- 2006-07-19 US US11/988,942 patent/US7932406B2/en not_active Expired - Fee Related
- 2006-07-19 EP EP06764221A patent/EP1907396B1/fr active Active
- 2006-07-19 AU AU2006271645A patent/AU2006271645B2/en not_active Ceased
- 2006-07-19 RU RU2008106100/04A patent/RU2405787C2/ru not_active IP Right Cessation
- 2006-07-19 JP JP2008521967A patent/JP5140583B2/ja not_active Expired - Fee Related
- 2006-07-19 RS RSP-2009/0079A patent/RS50782B/sr unknown
- 2006-07-19 CA CA2616064A patent/CA2616064C/fr not_active Expired - Fee Related
- 2006-07-19 DE DE602006003769T patent/DE602006003769D1/de active Active
- 2006-07-19 PT PT06764221T patent/PT1907396E/pt unknown
- 2006-07-19 WO PCT/EP2006/064420 patent/WO2007010007A1/fr not_active Ceased
- 2006-07-19 HR HR20090103T patent/HRP20090103T3/xx unknown
- 2006-07-19 UA UAA200801997A patent/UA90530C2/uk unknown
- 2006-07-19 DK DK06764221T patent/DK1907396T3/da active
- 2006-07-19 AT AT06764221T patent/ATE414707T1/de active
- 2006-07-19 ES ES06764221T patent/ES2317561T3/es active Active
- 2006-07-19 MX MX2008000961A patent/MX2008000961A/es active IP Right Grant
- 2006-07-19 KR KR1020087002443A patent/KR101357664B1/ko not_active Expired - Fee Related
- 2006-07-19 BR BRPI0613418-1A patent/BRPI0613418A2/pt not_active IP Right Cessation
- 2006-07-19 PL PL06764221T patent/PL1907396T3/pl unknown
- 2006-07-19 SI SI200630166T patent/SI1907396T1/sl unknown
- 2006-07-19 NZ NZ565923A patent/NZ565923A/en not_active IP Right Cessation
- 2006-07-19 CN CN2006800262703A patent/CN101223176B/zh not_active Expired - Fee Related
-
2008
- 2008-01-10 IL IL188716A patent/IL188716A0/en unknown
- 2008-01-18 TN TNP2008000030A patent/TNSN08030A1/fr unknown
- 2008-02-01 MA MA30614A patent/MA29690B1/fr unknown
- 2008-02-14 NO NO20080812A patent/NO20080812L/no not_active Application Discontinuation
- 2008-02-18 ZA ZA200801577A patent/ZA200801577B/xx unknown
-
2009
- 2009-02-18 CY CY20091100177T patent/CY1108804T1/el unknown
-
2010
- 2010-09-30 US US12/894,684 patent/US8193379B2/en not_active Expired - Fee Related
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