ATE416158T1 - Verfahren zur herstellung von amidderivaten und ihren zwischenverbindungen - Google Patents

Verfahren zur herstellung von amidderivaten und ihren zwischenverbindungen

Info

Publication number
ATE416158T1
ATE416158T1 AT96931297T AT96931297T ATE416158T1 AT E416158 T1 ATE416158 T1 AT E416158T1 AT 96931297 T AT96931297 T AT 96931297T AT 96931297 T AT96931297 T AT 96931297T AT E416158 T1 ATE416158 T1 AT E416158T1
Authority
AT
Austria
Prior art keywords
compounds
producing
amide derivatives
intermediate compounds
xvi
Prior art date
Application number
AT96931297T
Other languages
English (en)
Inventor
Takashi Inaba
Yasuki Yamada
James Shanley
Michael Deason
Original Assignee
Japan Tobacco Inc
Agouron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Tobacco Inc, Agouron Pharma filed Critical Japan Tobacco Inc
Application granted granted Critical
Publication of ATE416158T1 publication Critical patent/ATE416158T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
    • C07D321/02—Seven-membered rings
    • C07D321/04—Seven-membered rings not condensed with other rings
    • C07D321/06—1,3-Dioxepines; Hydrogenated 1,3-dioxepines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT96931297T 1995-09-26 1996-09-24 Verfahren zur herstellung von amidderivaten und ihren zwischenverbindungen ATE416158T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP24818495 1995-09-26

Publications (1)

Publication Number Publication Date
ATE416158T1 true ATE416158T1 (de) 2008-12-15

Family

ID=17174459

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96931297T ATE416158T1 (de) 1995-09-26 1996-09-24 Verfahren zur herstellung von amidderivaten und ihren zwischenverbindungen

Country Status (10)

Country Link
US (1) US6121468A (de)
EP (1) EP0984000B1 (de)
JP (1) JP3611332B2 (de)
AT (1) ATE416158T1 (de)
AU (1) AU717710B2 (de)
DE (1) DE69637770D1 (de)
DK (1) DK0984000T3 (de)
ES (1) ES2318852T3 (de)
PT (1) PT984000E (de)
WO (1) WO1997011938A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU729415B2 (en) 1996-07-12 2001-02-01 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
UA67727C2 (uk) * 1996-09-05 2004-07-15 Агурон Фармасевтікелс, Інк. Проміжні сполуки для одержання інгібіторів віл-протеази і способи одержання інгібіторів віл-протеази
US5925759A (en) 1996-09-05 1999-07-20 Agouron Pharmaceuticals, Inc. Methods of making HIV-protease inhibitors and intermediates for making HIV-protease inhibitors
US5962725A (en) 1996-09-05 1999-10-05 Agouron Pharmaceuticals, Inc. Intermediate compounds useful for making HIV protease inhibitors such as nelfinavir
CA2286013C (en) * 1997-04-10 2003-07-15 F. Hoffmann-La Roche Ag Process for making a butylthio-isoquinoline and intermediates therefor
US6130348A (en) 1997-04-10 2000-10-10 Hoffmann-La Roche Inc. Process for a phenylthiobutyl-isoquinoline and intermediates therefor
US6084107A (en) * 1997-09-05 2000-07-04 Agouron Pharmaceuticals, Inc. Intermediates for making HIV-protease inhibitors
IN188157B (de) * 1998-01-16 2002-08-24 Japan Tobacco Inc
WO1999054297A1 (en) * 1998-04-16 1999-10-28 Nagase & Company, Ltd. Process for preparing chloro alcohol derivatives and intermediates
US6403799B1 (en) 1999-10-21 2002-06-11 Agouron Pharmaceuticals, Inc. Methods for the preparation of intermediates in the synthesis of HIV-protease inhibitors
JP2004115510A (ja) * 2002-09-05 2004-04-15 Toray Fine Chemicals Co Ltd ピペラジン誘導体の製造方法
SG145574A1 (en) * 2003-05-08 2008-09-29 Pfizer Intermediates useful in the synthesis of hiv-protease inhibitors and methods for preparing the same
US20070192711A1 (en) * 2006-02-13 2007-08-16 Research In Motion Limited Method and arrangement for providing a primary actions menu on a handheld communication device
US8367832B2 (en) 2004-08-23 2013-02-05 Mylan Laboratories Limited Crystalline forms of Nelfinavir mesylate
US20110046199A1 (en) * 2008-01-17 2011-02-24 Purdue Research Foundation Small molecule inhibitors of hiv proteases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341756A (en) * 1980-01-31 1982-07-27 The Regents Of The University Of California Novel amino-dioxepane intermediates for the synthesis of new non-ionic contrast media
JPS56127373A (en) * 1980-01-31 1981-10-06 Univ California Novel amino-dioxepane intermediate for synthesizing novel nonionic contrast agent
DE3150917A1 (de) * 1981-12-18 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen "2-amino-1-(1,3-dioxolan-4-yl)-ethanol-verbindungen, deren herstellung und verwendung zur weiterverarbeitung"
MX9308016A (es) * 1992-12-22 1994-08-31 Lilly Co Eli Compuestos inhibidores de la proteasa del virus de la inmunodeficiencia humana, procedimiento para su preparacion y formulacion farmaceutica que los contiene.
US5733906A (en) * 1993-10-12 1998-03-31 Eli Lilly And Company Inhibitors of HIV Protease useful for the treatment of Aids
US5484926A (en) * 1993-10-07 1996-01-16 Agouron Pharmaceuticals, Inc. HIV protease inhibitors
EP0668274B1 (de) * 1994-02-21 1998-08-26 PLIVA, farmaceutska, kemijska, prehrambena i kozmeticka industrija, dionicko drustvo Sulfonamidodioxepane mit hypoglykämischen Eigenschaften, Methoden zu ihrer Herstellung, ihre Zwischenprodukte und Salze

Also Published As

Publication number Publication date
WO1997011938A1 (en) 1997-04-03
AU7002196A (en) 1997-04-17
EP0984000A4 (de) 2004-08-11
ES2318852T3 (es) 2009-05-01
US6121468A (en) 2000-09-19
JP3611332B2 (ja) 2005-01-19
DK0984000T3 (da) 2009-04-06
EP0984000A1 (de) 2000-03-08
EP0984000B1 (de) 2008-12-03
PT984000E (pt) 2009-02-06
AU717710B2 (en) 2000-03-30
DE69637770D1 (de) 2009-01-15

Similar Documents

Publication Publication Date Title
ATE416158T1 (de) Verfahren zur herstellung von amidderivaten und ihren zwischenverbindungen
AU2001252595A1 (en) Process for producing optically active sulfoxide derivative
ATE174903T1 (de) Neues verfahren zur herstellung von 7- (substituierten)-9-((substistuierter
DE69415319D1 (de) Verfahren zur herstellung von piperidinderivaten
ATE280240T1 (de) Enzymatische verfahren zur aüftrennüng von enantiomeren-mischungen nützlich als zwischenprodukte zur herstellung von taxanen
ATE145891T1 (de) Verfahren zur herstellung von alkoxyiminoacetamid-derivaten und ein zwischenproduckt dafür
ATE303983T1 (de) Indanone und carbamat, und ihre verwendung in der herstellung von arthropoziden oxadiazinen
DE69327567D1 (de) Verfahren zur Herstellung von Alanylglutamin
ATE234294T1 (de) Verfahren zur herstellung von n-(4-cyan-3- trifluormethylphenyl)-3-(4-flurophenylsulfonyl) 2-hydroxy-2-methylpropionamid
ATE288891T1 (de) Verfahren zur herstellung von amid-derivaten und ihren zwischenverbindungen
ATE187168T1 (de) Verfahren zur herstellung von 1-substituierten 2- cyanoimidazolen
DE69231815D1 (de) Verfahren zur Herstellung von Cephalosporinen und Zwischenprodukte in diesem Verfahren
EP1589018A4 (de) Herstellungsverfahren für hexahydrofurofuranol-derivate, zwischenprodukt davon und herstellungsverfahren dafür
ATE277915T1 (de) Verfahren sowie neue zwischenprodukte zur herstellung von isoxazolin-3-yl-acylbenzolen
DE60200535D1 (de) Verfahren zur Herstellung von hoch reinem Pemirolast
DE69523038D1 (de) Verfahren zur herstellung von hiv proteasinhibitoren
DE69432176D1 (de) Verfahren zur herstellung von hiv protease inhibitoren
DE69426979D1 (de) Verfahren zur herstellung von hiv-proteasehemmern
ATE201410T1 (de) Verfahren zur herstellung von 1-(4,5-dihydro)2- thiazolyl-3-azetidinthiolderivaten
ATE277919T1 (de) Verfahren zur herstellung von baccatin iii- derivativen
ATE234288T1 (de) Verfahren zur herstellung eines buthylthuio- isochinolinderivates und zwischenprodukte dafür
DE60039533D1 (de) Verbessertes verfahren zur herstellung von 2s,3s-n-isobutyl-n-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamid hydrochlorid und anderen derivaten von 2-hydroxy-1,3-diamin
DK0492350T3 (da) Fremgangsmåde til fremstilling af (S)-vinyl- og (S)-allenyl-GABA
DE60144570D1 (de) Verfahren zur herstellung von optisch aktiven sulfonamiden und zwischenprodukte zur deren synthese
ATE151428T1 (de) Verfahren zur herstellung von 3- exomethylencephamsulfoxydderivate und zwischenverbindungen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0984000

Country of ref document: EP

REN Ceased due to non-payment of the annual fee