PT984000E - Processo para a produção de derivados amina e compostos intermediários - Google Patents

Processo para a produção de derivados amina e compostos intermediários Download PDF

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Publication number
PT984000E
PT984000E PT96931297T PT96931297T PT984000E PT 984000 E PT984000 E PT 984000E PT 96931297 T PT96931297 T PT 96931297T PT 96931297 T PT96931297 T PT 96931297T PT 984000 E PT984000 E PT 984000E
Authority
PT
Portugal
Prior art keywords
optionally substituted
compound
preferred
solvents
enantiomer
Prior art date
Application number
PT96931297T
Other languages
English (en)
Portuguese (pt)
Inventor
Takashi Inaba
Yasuki Yamada
James Shanley
Michael Deason
Original Assignee
Agouron Pharma
Japan Tobacco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agouron Pharma, Japan Tobacco Inc filed Critical Agouron Pharma
Publication of PT984000E publication Critical patent/PT984000E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
    • C07D321/02—Seven-membered rings
    • C07D321/04—Seven-membered rings not condensed with other rings
    • C07D321/06—1,3-Dioxepines; Hydrogenated 1,3-dioxepines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PT96931297T 1995-09-26 1996-09-24 Processo para a produção de derivados amina e compostos intermediários PT984000E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP24818495 1995-09-26

Publications (1)

Publication Number Publication Date
PT984000E true PT984000E (pt) 2009-02-06

Family

ID=17174459

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96931297T PT984000E (pt) 1995-09-26 1996-09-24 Processo para a produção de derivados amina e compostos intermediários

Country Status (10)

Country Link
US (1) US6121468A (de)
EP (1) EP0984000B1 (de)
JP (1) JP3611332B2 (de)
AT (1) ATE416158T1 (de)
AU (1) AU717710B2 (de)
DE (1) DE69637770D1 (de)
DK (1) DK0984000T3 (de)
ES (1) ES2318852T3 (de)
PT (1) PT984000E (de)
WO (1) WO1997011938A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6281212B1 (en) 1996-07-12 2001-08-28 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US5925759A (en) 1996-09-05 1999-07-20 Agouron Pharmaceuticals, Inc. Methods of making HIV-protease inhibitors and intermediates for making HIV-protease inhibitors
US5962725A (en) 1996-09-05 1999-10-05 Agouron Pharmaceuticals, Inc. Intermediate compounds useful for making HIV protease inhibitors such as nelfinavir
UA67727C2 (uk) * 1996-09-05 2004-07-15 Агурон Фармасевтікелс, Інк. Проміжні сполуки для одержання інгібіторів віл-протеази і способи одержання інгібіторів віл-протеази
DE69812079T2 (de) * 1997-04-10 2003-12-18 F. Hoffmann-La Roche Ag, Basel Verfahren zur herstellung eines buthylthuio-isochinolinderivates und zwischenprodukte dafür
US6130348A (en) * 1997-04-10 2000-10-10 Hoffmann-La Roche Inc. Process for a phenylthiobutyl-isoquinoline and intermediates therefor
US6084107A (en) * 1997-09-05 2000-07-04 Agouron Pharmaceuticals, Inc. Intermediates for making HIV-protease inhibitors
IN188157B (de) 1998-01-16 2002-08-24 Japan Tobacco Inc
WO1999054297A1 (en) * 1998-04-16 1999-10-28 Nagase & Company, Ltd. Process for preparing chloro alcohol derivatives and intermediates
US6403799B1 (en) 1999-10-21 2002-06-11 Agouron Pharmaceuticals, Inc. Methods for the preparation of intermediates in the synthesis of HIV-protease inhibitors
JP2004115510A (ja) * 2002-09-05 2004-04-15 Toray Fine Chemicals Co Ltd ピペラジン誘導体の製造方法
CN1819993A (zh) * 2003-05-08 2006-08-16 美国辉瑞有限公司 用于合成hiv－蛋白酶抑制剂的中间体及其制备方法
US20070192711A1 (en) * 2006-02-13 2007-08-16 Research In Motion Limited Method and arrangement for providing a primary actions menu on a handheld communication device
EP1814858B1 (de) 2004-08-23 2015-03-18 Mylan Laboratories Limited Neue kristalline formen von nelfinavirmesylat
WO2009091941A1 (en) * 2008-01-17 2009-07-23 Purdue Research Foundation Small molecule inhibitors of hiv proteases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56127373A (en) * 1980-01-31 1981-10-06 Univ California Novel amino-dioxepane intermediate for synthesizing novel nonionic contrast agent
US4341756A (en) * 1980-01-31 1982-07-27 The Regents Of The University Of California Novel amino-dioxepane intermediates for the synthesis of new non-ionic contrast media
DE3150917A1 (de) * 1981-12-18 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen "2-amino-1-(1,3-dioxolan-4-yl)-ethanol-verbindungen, deren herstellung und verwendung zur weiterverarbeitung"
US5733906A (en) * 1993-10-12 1998-03-31 Eli Lilly And Company Inhibitors of HIV Protease useful for the treatment of Aids
MX9308016A (es) * 1992-12-22 1994-08-31 Lilly Co Eli Compuestos inhibidores de la proteasa del virus de la inmunodeficiencia humana, procedimiento para su preparacion y formulacion farmaceutica que los contiene.
US5484926A (en) * 1993-10-07 1996-01-16 Agouron Pharmaceuticals, Inc. HIV protease inhibitors
SK22795A3 (en) * 1994-02-21 1995-09-13 Pliva Pharm & Chem Works Sulfonamidodioxepanes, method of their preparation, intermediates, salts and their using

Also Published As

Publication number Publication date
AU717710B2 (en) 2000-03-30
ATE416158T1 (de) 2008-12-15
ES2318852T3 (es) 2009-05-01
EP0984000B1 (de) 2008-12-03
EP0984000A4 (de) 2004-08-11
US6121468A (en) 2000-09-19
DE69637770D1 (de) 2009-01-15
EP0984000A1 (de) 2000-03-08
DK0984000T3 (da) 2009-04-06
AU7002196A (en) 1997-04-17
WO1997011938A1 (en) 1997-04-03
JP3611332B2 (ja) 2005-01-19

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