PT97500A - Processo de producao de lipossomas e de preparados farmaceuticos contendo aqueles lipossomas - Google Patents

Processo de producao de lipossomas e de preparados farmaceuticos contendo aqueles lipossomas

Info

Publication number: PT97500A
Authority: PT; Portugal
Prior art keywords: liposomes; formula; production process; pharmaceutical preparations; pnn
Prior art date: 1990-04-27

Application number

PT97500A

Other languages

English (en)

Other versions

PT97500B (pt

Inventor

Hansjorg Eibl

Clemens Unger

Petra Kaufmann-Kolle

Original Assignee

Max Planck Gesellschaft

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-04-27

Filing date

1991-04-26

Publication date

1992-01-31

1991-04-26 Application filed by Max Planck Gesellschaft filed Critical Max Planck Gesellschaft

1992-01-31 Publication of PT97500A publication Critical patent/PT97500A/pt

1998-08-31 Publication of PT97500B publication Critical patent/PT97500B/pt

Links

239000002502 liposome Substances 0.000 title abstract 5
238000004519 manufacturing process Methods 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
239000013543 active substance Substances 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
208000019423 liver disease Diseases 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
125000002811 oleoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])/C([H])=C([H])\C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
125000001117 oleyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])/C([H])=C([H])\C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
210000000056 organ Anatomy 0.000 abstract 1
239000000546 pharmaceutical excipient Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
General Health & Medical Sciences (AREA)
Dispersion Chemistry (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Manufacturing Of Micro-Capsules (AREA)

PT97500A 1990-04-27 1991-04-26 Processo de producao de lipossomas e de preparados farmaceuticos contendo aqueles lipossomas PT97500B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4013632A DE4013632A1 (de)	1990-04-27	1990-04-27	Liposomen mit positiver ueberschussladung

Publications (2)

Publication Number	Publication Date
PT97500A true PT97500A (pt)	1992-01-31
PT97500B PT97500B (pt)	1998-08-31

Family

ID=6405307

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT97500A PT97500B (pt)	1990-04-27	1991-04-26	Processo de producao de lipossomas e de preparados farmaceuticos contendo aqueles lipossomas

Country Status (11)

Country	Link
EP (1)	EP0526531B1 (pt)
JP (1)	JPH05506661A (pt)
AT (1)	ATE107503T1 (pt)
AU (1)	AU643282B2 (pt)
CA (1)	CA2081119A1 (pt)
DE (2)	DE4013632A1 (pt)
DK (1)	DK0526531T3 (pt)
ES (1)	ES2056648T3 (pt)
IE (1)	IE62548B1 (pt)
PT (1)	PT97500B (pt)
WO (1)	WO1991016880A1 (pt)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH087409B2 (ja) *	1988-10-03	1996-01-29	富士写真フイルム株式会社	ハロゲン化銀カラー写真感光材料の処理方法
US5264618A (en) *	1990-04-19	1993-11-23	Vical, Inc.	Cationic lipids for intracellular delivery of biologically active molecules
DE4208527A1 (de) *	1992-03-17	1993-09-23	Max Planck Gesellschaft	Liposomen mit negativer ueberschussladung
US5552155A (en) *	1992-12-04	1996-09-03	The Liposome Company, Inc.	Fusogenic lipsomes and methods for making and using same
JPH09500013A (ja)	1993-06-01	1997-01-07	ライフ・テクノロジーズ・インコーポレイテッド	カチオン性脂質による遺伝子免疫
EP0638639B1 (en) *	1993-08-10	2000-04-12	Akzo Nobel N.V.	Biodegradable fabric softening composition
WO1995027478A1 (en) *	1994-04-12	1995-10-19	The Liposome Company, Inc.	Fusogenic liposomes and methods of making and using same
US5429755A (en) *	1994-06-16	1995-07-04	Lever Brothers Company	Fabric conditioning molecules derived from glycerol and betaine
DE69600850T2 (de) *	1995-02-24	1999-04-15	Kao Corp., Tokio/Tokyo	Quaternierte Ammoniumsalze, Verfahren zu ihrer Herstellung und diese enthaltende Weichspülzusammensetzungen
EP0863749A2 (en)	1995-11-30	1998-09-16	Vical Incorporated	Complex cationic lipids
DE19835611A1 (de)	1998-08-06	2000-02-10	Max Planck Gesellschaft	Neuartige Phospholipide mit synthetischen, ungesättigten Alkyl- und Acylketten
EP1261620A2 (en) *	2000-02-07	2002-12-04	Roche Diagnostics Corporation	Cationic amphiphiles for use in nucleic acid transfection
ITMI20032185A1 (it) *	2003-11-12	2005-05-13	Chemi Spa	Processo per la sintesi di lipidi cationici.
DE102004057303A1 (de) *	2004-11-26	2006-06-01	Merck Patent Gmbh	Stabile Kristallmodifikationen von DOTAP Chlorid
CA3144493A1 (en) *	2006-10-03	2008-04-10	Arbutus Biopharma Corporation	Lipid containing formulations
EP4481047A3 (en) *	2010-06-03	2025-04-16	Alnylam Pharmaceuticals, Inc.	Biodegradable lipids for the delivery of active agents
ES2562274T3 (es)	2010-10-06	2016-03-03	Fundació Institut De Recerca Biomèdica (Irb Barcelona)	Procedimiento para el diagnóstico, pronóstico y tratamiento de metástasis de cáncer de mama
CN108285422A (zh)	2011-05-20	2018-07-17	默克专利股份有限公司	稳定的dotap氯化物晶体变体
JP2013043885A (ja) *	2011-08-26	2013-03-04	Kansai Bunri Sogo Gakuen	デヒドロアミノ酸含有グリセロール誘導体
DE21212055T1 (de)	2011-12-07	2022-08-04	Alnylam Pharmaceuticals, Inc.	Biologisch abbaubare lipide zur freisetzung von wirkstoffen
EP2650682A1 (en)	2012-04-09	2013-10-16	Fundació Privada Institut de Recerca Biomèdica	Method for the prognosis and treatment of cancer metastasis
CA3025264A1 (en)	2016-05-25	2017-11-30	Inbiomotion S.L.	Therapeutic treatment of breast cancer based on c-maf status
CA3082728A1 (en)	2017-11-22	2019-05-31	Inbiomotion S.L.	Therapeutic treatment of breast cancer based on c-maf status
KR102054401B1 (ko)	2018-03-26	2019-12-10	주식회사 엔지켐생명과학	1,2-디아실글리세롤 화합물, 그 제조방법 및 이를 유효성분으로 함유하는 면역조절제
JP7685776B2 (ja) *	2022-11-08	2025-05-30	美洛生物科技股▲ふん▼有限公司	カチオン性脂質及びその使用
KR20240174509A (ko)	2023-06-07	2024-12-17	포항공과대학교 산학협력단	핵산 치료제에 사용되는 기능성 지질 라이브러리를 합성하기 위한 단일 연속 유동 합성 방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2752553C2 (de) *	1977-11-24	1985-07-25	Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen	Neue phospholipidartige Verbindungen, ihre Verwendung zur Herstellung von Pflanzenhybriden und Verfahren zu ihrer Herstellung
AU5632880A (en) *	1979-04-30	1980-11-06	Brown, G.	Convertible sleeping and seating apparatus
EP0088046B1 (de) *	1982-02-17	1987-12-09	Ciba-Geigy Ag	Lipide in wässriger Phase
JPH0662517B2 (ja) *	1985-01-07	1994-08-17	シンテツクス（ユー・エス・エイ）インコーポレイテツド	置換アルキルートリ置換アンモニウム界面活性剤
US5223263A (en) *	1988-07-07	1993-06-29	Vical, Inc.	Liponucleotide-containing liposomes
JPS632921A (ja) *	1986-06-20	1988-01-07	Yamanouchi Pharmaceut Co Ltd	リポソ−ム製剤

1990
- 1990-04-27 DE DE4013632A patent/DE4013632A1/de not_active Withdrawn
1991
- 1991-04-25 AT AT91908541T patent/ATE107503T1/de not_active IP Right Cessation
- 1991-04-25 CA CA002081119A patent/CA2081119A1/en not_active Abandoned
- 1991-04-25 DK DK91908541.5T patent/DK0526531T3/da active
- 1991-04-25 DE DE59102030T patent/DE59102030D1/de not_active Expired - Fee Related
- 1991-04-25 AU AU77702/91A patent/AU643282B2/en not_active Ceased
- 1991-04-25 EP EP91908541A patent/EP0526531B1/de not_active Expired - Lifetime
- 1991-04-25 JP JP91508158A patent/JPH05506661A/ja active Pending
- 1991-04-25 WO PCT/EP1991/000796 patent/WO1991016880A1/de not_active Ceased
- 1991-04-25 ES ES91908541T patent/ES2056648T3/es not_active Expired - Lifetime
- 1991-04-26 IE IE142791A patent/IE62548B1/en not_active IP Right Cessation
- 1991-04-26 PT PT97500A patent/PT97500B/pt not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE4013632A1 (de)	1991-10-31
AU643282B2 (en)	1993-11-11
PT97500B (pt)	1998-08-31
CA2081119A1 (en)	1991-10-28
IE62548B1 (en)	1995-02-08
DE59102030D1 (de)	1994-07-28
IE911427A1 (en)	1991-11-06
JPH05506661A (ja)	1993-09-30
AU7770291A (en)	1991-11-27
WO1991016880A1 (de)	1991-11-14
ATE107503T1 (de)	1994-07-15
EP0526531A1 (de)	1993-02-10
EP0526531B1 (de)	1994-06-22
ES2056648T3 (es)	1994-10-01
DK0526531T3 (da)	1994-08-22

Legal Events

Date

Code

Title

Description

1992-01-31

BB1A

Laying open of patent application

Effective date: 19910916

1998-08-31

FG3A

Patent granted, date of granting

Effective date: 19980513

2000-03-31

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19991130

Publication	Publication Date	Title
AU643282B2 (en)	1993-11-11	Liposomes with positive excess charge
CA2078790A1 (en)	1992-07-22	3-benzylidene-1-carbamoyl-2-pyrrolidone analogues
EA200000592A1 (ru)	2000-12-25	Азаполициклические соединения, конденсированные с арилом
NO950849D0 (no)	1995-03-03	Derivater av valproin og 2-valproensyreamider og anvendelse som antikonvulsanter
TR200102038T2 (tr)	2002-01-21	Amid bileşenler
ATE63124T1 (de)	1991-05-15	Prodrugverbindungen, verfahren zu deren herstellung und diese enthaltende zubereitungen mit verzoegerter freisetzung.
EA200100983A1 (ru)	2002-10-31	Производные 13-метилэритромицина
FR2358418A1 (fr)	1978-02-10	Nouveaux polygalactosidosaccharoses sulfates utiles notamment comme inhibiteurs du complement
FI961507A0 (fi)	1996-04-03	Antrasyklinonijohdannaiset ja niiden käyttö amyloidoosissa
DE69529624D1 (de)	2003-03-20	Neue endiyn-chinonimine und verfahren zu deren herstellung und verwendung
PT90725A (pt)	1989-12-29	Processo para a preparacao de novos compostos cefem
PT98375A (pt)	1992-05-29	Processo de preparacao de compostos de piperidina e de composicoes farmaceuticas
ES2116612T3 (es)	1998-07-16	Nuevas bis-naftalimidas para el tratamiento del cancer.
HUP0203275A2 (hu)	2003-01-28	1-(Gyűrűs amino)-alkilciklohexán-származékok, ezeket tartalmazó görcsoldó hatású gyógyszerkészítmények, valamint ezek alkalmazása
IL125926A0 (en)	1999-04-11	Compounds related to the amidinium family pharmaceutical compositions containing them and uses thereof
AR029618A1 (es)	2003-07-10	Compuestos de amida , procedimientos para prepararlos, las composiciones farmaceuticas que los contienen y el uso de dichos compuestos para la fabricacion de medicamentos
IE44765L (en)	1977-12-03	N-substituted benzamides.
DK0728138T3 (da)	2002-05-13	Anthracyclinderivater
SE8600046L (sv)	1987-07-08	Anvendning av en esterforening som temporer baktericid och produkt innehallande esterforeningen
DE69330601D1 (de)	2001-09-20	Serotoninergische ergolin derivate
PT89082A (pt)	1988-12-01	Processo para a preparacao de novos derivados n-(23-vinblastinoilicos)do acido 1-amino-metilfosfonico
ATE92315T1 (de)	1993-08-15	Aminosaeurederivate enthaltende antikonvulsive zusammensetzungen und verwendung dieser aminosaeurederivate.
PT92540A (pt)	1990-06-29	Processo para a preparacao de derivados de anfotericina b
SE8303913L (sv)	1984-01-09	Heterocykliska foreningar
FI834136A0 (fi)	1983-11-11	1-aroyl-5-oxo-2-pyrrolidin-propansyror och mostvarande estrar