ATE417930T1 - Proteinkinase npk-110 - Google Patents

Proteinkinase npk-110

Info

Publication number
ATE417930T1
ATE417930T1 AT95937855T AT95937855T ATE417930T1 AT E417930 T1 ATE417930 T1 AT E417930T1 AT 95937855 T AT95937855 T AT 95937855T AT 95937855 T AT95937855 T AT 95937855T AT E417930 T1 ATE417930 T1 AT E417930T1
Authority
AT
Austria
Prior art keywords
protein kinase
npk
alzheimer
maps
cancer
Prior art date
Application number
AT95937855T
Other languages
English (en)
Inventor
Eckhard Mandelkow
Eva-Maria Mandelkow
Jacek Biernat
Gerard Drewes
Original Assignee
Max Planck Gesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft filed Critical Max Planck Gesellschaft
Application granted granted Critical
Publication of ATE417930T1 publication Critical patent/ATE417930T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT95937855T 1994-10-28 1995-10-30 Proteinkinase npk-110 ATE417930T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94117122 1994-10-28

Publications (1)

Publication Number Publication Date
ATE417930T1 true ATE417930T1 (de) 2009-01-15

Family

ID=8216419

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95937855T ATE417930T1 (de) 1994-10-28 1995-10-30 Proteinkinase npk-110

Country Status (12)

Country Link
US (2) US6579691B1 (de)
EP (1) EP0791067B1 (de)
JP (1) JPH10508199A (de)
KR (1) KR100275591B1 (de)
CN (1) CN1168699A (de)
AT (1) ATE417930T1 (de)
CA (1) CA2203910A1 (de)
DE (1) DE69535901D1 (de)
HU (1) HUT77081A (de)
NO (1) NO971966L (de)
NZ (1) NZ295371A (de)
WO (1) WO1996013592A2 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993011231A1 (en) * 1991-12-06 1993-06-10 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Tools for the diagnosis and treatment of alzheimer's disease
AU6421498A (en) * 1997-04-28 1998-11-24 Helix Research Institute Serine/threonine protein kinase
WO2001081558A2 (en) * 2000-04-25 2001-11-01 Millennium Pharmaceuticals, Inc. 13295 novel protein kinase molecules and uses therefor
AU2002239571A1 (en) * 2000-12-06 2002-06-18 Incyte Genomics, Inc. Kinases and phosphatases sequences, and use thereof
US7119185B2 (en) * 2000-12-21 2006-10-10 Trustees Of The University Of Pennsylvania Hormonally up-regulated, neu-tumor-associated kinase
ATE394115T1 (de) * 2001-02-27 2008-05-15 Brni Neurosciences Inst Diagnose der alzheimer-krankheit auf basis von mitogenaktivierter proteinkinase-phosphorylierung
ATE483976T1 (de) 2001-06-05 2010-10-15 Exelixis Inc Gfats als modifikatoren des p53-wegs und verwendungsverfahren
US6492156B1 (en) * 2001-10-31 2002-12-10 Pe Corporation (Ny) Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
EP1633856A4 (de) * 2003-06-19 2007-07-18 Exelixis Inc Marks als modifikatoren des pten-wegs und verwendungsverfahren
US8273536B2 (en) 2003-06-19 2012-09-25 Exelixis, Inc. Marks as modifers of the PTEN pathway and methods of use
CN100424184C (zh) * 2005-12-09 2008-10-08 浙江大学 疱疹类病毒基因芯片及其应用
US9433922B2 (en) * 2007-08-14 2016-09-06 Emd Millipore Corporation Media for membrane ion exchange chromatography based on polymeric primary amines, sorption device containing that media, and chromatography scheme and purification method using the same
KR101294725B1 (ko) * 2010-12-30 2013-08-08 연세대학교 산학협력단 인산화된 grasp를 포함하는 낭포성섬유증 치료용 약학 조성물
US9518101B2 (en) * 2011-09-19 2016-12-13 Axon Neuroscience Se Protein-based therapy and diagnosis of tau-mediated pathology in alzheimer's disease
EP3658172A4 (de) 2017-07-25 2021-05-05 TrueBinding, Inc. Behandlung von krebs durch blockierung der interaktion von tim-3 und seinem liganden
CN113711036B (zh) 2019-01-30 2025-03-18 真和制药有限公司 抗gal3抗体及其用途
CN116157151A (zh) 2020-05-26 2023-05-23 真和制药有限公司 通过阻断半乳凝素-3治疗炎性疾病的方法
CN117551674B (zh) * 2023-11-20 2024-10-18 内蒙古农业大学 沙葱萤叶甲微管亲和调节激酶GdMARK2基因的克隆及其功能

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0544942A1 (de) * 1991-12-06 1993-06-09 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Neue Werkzeuge für die Diagnose und die Behandlung der Alzheimer-Krankheit

Also Published As

Publication number Publication date
HUT77081A (hu) 1998-03-02
EP0791067A2 (de) 1997-08-27
CN1168699A (zh) 1997-12-24
KR100275591B1 (ko) 2001-02-01
US20040038361A1 (en) 2004-02-26
WO1996013592A3 (en) 1996-08-01
CA2203910A1 (en) 1996-05-09
MX9703101A (es) 1998-07-31
JPH10508199A (ja) 1998-08-18
NO971966D0 (no) 1997-04-28
DE69535901D1 (de) 2009-01-29
AU714636B2 (en) 2000-01-06
US6579691B1 (en) 2003-06-17
NO971966L (no) 1997-06-19
NZ295371A (en) 1998-11-25
US20030104516A1 (en) 2003-06-05
US7485712B2 (en) 2009-02-03
EP0791067B1 (de) 2008-12-17
WO1996013592A2 (en) 1996-05-09
AU3870295A (en) 1996-05-23

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