ATE418541T1 - Verfahren zur herstellung von carvedilol - Google Patents

Verfahren zur herstellung von carvedilol

Info

Publication number: ATE418541T1
Authority: AT; Austria
Prior art keywords: carvedilol; reaction; producing; carvediol; epoxypropoxy
Prior art date: 2005-07-06

Application number

AT06116752T

Other languages

English (en)

Inventor

Ashok Kumar

Ashvini Saxena

Anindya Bhattacharyya

Sengar Amit Vikram Singh

Gunjan Pramod Pathak

Satish Rajanikant Soudagar

Pramil Kumar Mathur

Avinash Manohar Nijasure

Sanjukumar Motiram Salunke

Prashant Gautam

Thakur Gajendrasingh Ramsingh

Dilip Uttam Jadhav

Original Assignee

Ipca Lab Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-07-06

Filing date

2006-07-06

Publication date

2009-01-15

2006-07-06 Application filed by Ipca Lab Ltd filed Critical Ipca Lab Ltd

2009-01-15 Application granted granted Critical

2009-01-15 Publication of ATE418541T1 publication Critical patent/ATE418541T1/de

Links

NPAKNKYSJIDKMW-UHFFFAOYSA-N carvedilol Chemical compound COC1=CC=CC=C1OCCNCC(O)COC1=CC=CC2=NC3=CC=C[CH]C3=C12 NPAKNKYSJIDKMW-UHFFFAOYSA-N 0.000 title abstract 4
229960004195 carvedilol Drugs 0.000 title abstract 4
238000004519 manufacturing process Methods 0.000 title 1
238000006243 chemical reaction Methods 0.000 abstract 3
CKJRKLKVCHMWLV-UHFFFAOYSA-N 2-(2-methoxyphenoxy)ethanamine Chemical compound COC1=CC=CC=C1OCCN CKJRKLKVCHMWLV-UHFFFAOYSA-N 0.000 abstract 1
SVWKIGRDISDRLO-UHFFFAOYSA-N 4-(oxiran-2-ylmethoxy)-9h-carbazole Chemical compound C=1C=CC=2NC3=CC=CC=C3C=2C=1OCC1CO1 SVWKIGRDISDRLO-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
239000012535 impurity Substances 0.000 abstract 1
238000002955 isolation Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000003880 polar aprotic solvent Substances 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)

AT06116752T 2005-07-06 2006-07-06 Verfahren zur herstellung von carvedilol ATE418541T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IN807MU2005		2005-07-06

Publications (1)

Publication Number	Publication Date
ATE418541T1 true ATE418541T1 (de)	2009-01-15

Family

ID=37074203

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT06116752T ATE418541T1 (de)	2005-07-06	2006-07-06	Verfahren zur herstellung von carvedilol

Country Status (4)

Country	Link
US (1)	US20070027202A1 (de)
EP (1)	EP1741700B1 (de)
AT (1)	ATE418541T1 (de)
DE (1)	DE602006004403D1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL153688A0 (en) *	2000-06-28	2003-07-06	Teva Pharma	Carvedilol
PL371409A1 (en) *	2002-01-15	2005-06-13	Teva Pharmaceutical Industries Ltd.	Crystalline solids of carvedilol and processes for their preparation
EP1781611A1 (de) *	2005-06-09	2007-05-09	Teva Pharmaceutical Industries Ltd.	Kristalline formen des carvediols und verfahren zu ihrer herstellung
WO2008002683A2 (en) *	2006-06-28	2008-01-03	Teva Pharmaceutical Industries Ltd.	Polymorphous forms of carvedilol phosphate
WO2008038301A1 (en) *	2006-09-26	2008-04-03	Morepen Laboratories Limited	A process for the preparation of carvedilol
US20080207726A1 (en) *	2007-02-26	2008-08-28	Santiago Ini	Process for the purification of carvedilol or its salts thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2815926A1 (de) *	1978-04-13	1979-10-18	Boehringer Mannheim Gmbh	Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US6730326B2 (en) *	1997-07-22	2004-05-04	Roche Diagnostics Gmbh	Thermodynamically stable modification of 1-(4-carbazolyl-oxy-3[2-(2-methoxyphenoxy)-ethylamino]-2-propanol process for its preparation and pharmaceutical compositions containing it
WO2004094378A1 (en) *	2003-04-21	2004-11-04	Matrix Laboratories Ltd	Process for the preparation of carvedilol form-ii
US7482471B2 (en) *	2003-06-20	2009-01-27	Sun Pharmaceutical Industries Limited	Process for preparation of 1-[9H-carbazol-4-yloxy]-3-[{2-(2-(-methoxy)phenoxy)-ethyl}-amino]-propan-2-ol

2006
- 2006-07-05 US US11/480,526 patent/US20070027202A1/en not_active Abandoned
- 2006-07-06 EP EP06116752A patent/EP1741700B1/de not_active Not-in-force
- 2006-07-06 AT AT06116752T patent/ATE418541T1/de not_active IP Right Cessation
- 2006-07-06 DE DE602006004403T patent/DE602006004403D1/de active Active

Also Published As

Publication number	Publication date
DE602006004403D1 (de)	2009-02-05
US20070027202A1 (en)	2007-02-01
EP1741700B1 (de)	2008-12-24
EP1741700A1 (de)	2007-01-10

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Legal Events

Date	Code	Title	Description
2009-06-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties