ATE420112T1 - Krebsantigene, basierend auf dem tumorunterdrückenden genprodukt wt1 - Google Patents
Krebsantigene, basierend auf dem tumorunterdrückenden genprodukt wt1Info
- Publication number
- ATE420112T1 ATE420112T1 AT99933205T AT99933205T ATE420112T1 AT E420112 T1 ATE420112 T1 AT E420112T1 AT 99933205 T AT99933205 T AT 99933205T AT 99933205 T AT99933205 T AT 99933205T AT E420112 T1 ATE420112 T1 AT E420112T1
- Authority
- AT
- Austria
- Prior art keywords
- gene product
- cancer antigens
- tumor suppressive
- antigens based
- suppressive gene
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 239000000427 antigen Substances 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 230000002100 tumorsuppressive effect Effects 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001152—Transcription factors, e.g. SOX or c-MYC
- A61K39/001153—Wilms tumor 1 [WT1]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4242—Transcription factors, e.g. SOX or c-MYC
- A61K40/4243—Wilms tumor 1 [WT1]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP21809398 | 1998-07-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE420112T1 true ATE420112T1 (de) | 2009-01-15 |
Family
ID=16714530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99933205T ATE420112T1 (de) | 1998-07-31 | 1999-07-30 | Krebsantigene, basierend auf dem tumorunterdrückenden genprodukt wt1 |
Country Status (15)
| Country | Link |
|---|---|
| US (7) | US7030212B1 (de) |
| EP (3) | EP1103564B1 (de) |
| JP (2) | JP4422903B2 (de) |
| KR (1) | KR100767554B1 (de) |
| CN (4) | CN102198266A (de) |
| AT (1) | ATE420112T1 (de) |
| AU (1) | AU4932199A (de) |
| BR (1) | BRPI9912663B8 (de) |
| CA (1) | CA2337743C (de) |
| DE (1) | DE69940264D1 (de) |
| DK (1) | DK1103564T3 (de) |
| ES (1) | ES2318898T3 (de) |
| HK (1) | HK1038929B (de) |
| PT (1) | PT1103564E (de) |
| WO (1) | WO2000006602A1 (de) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2243235C (en) | 1996-01-17 | 2010-08-10 | Imperial College Innovations Limited | Immunotherapy using cytotoxic t lymphocytes (ctl) |
| AU4932199A (en) * | 1998-07-31 | 2000-02-21 | Haruo Sugiyama | Cancer antigens based on tumor suppressor gene wt1 product |
| US7144581B2 (en) | 2000-10-09 | 2006-12-05 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
| US7655249B2 (en) | 1998-09-30 | 2010-02-02 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
| US7901693B2 (en) | 1998-09-30 | 2011-03-08 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
| US7063854B1 (en) | 1998-09-30 | 2006-06-20 | Corixa Corporation | Composition and methods for WTI specific immunotherapy |
| AR021849A1 (es) * | 1998-09-30 | 2002-08-07 | Corixa Corp | Composiciones y metodos para la inmunoterapia especifica de wt1 |
| US7329410B1 (en) | 1998-09-30 | 2008-02-12 | Corixa Corporation | Compositions and method for WT1 specific immunotherapy |
| US7115272B1 (en) | 1998-09-30 | 2006-10-03 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
| GB9823897D0 (en) * | 1998-11-02 | 1998-12-30 | Imp College Innovations Ltd | Immunotherapeutic methods and molecules |
| WO2001025273A2 (en) * | 1999-10-04 | 2001-04-12 | Corixa Corporation | Compositions and methods for wt1 specific immunotherapy |
| CA2401070A1 (en) * | 2000-02-22 | 2001-08-30 | Corixa Corporation | Compositions and methods for diagnosis and therapy of malignant mesothelioma |
| EP1371664B1 (de) * | 2001-03-22 | 2008-01-09 | International Institute of Cancer Immunology, Inc. | Wti-modifiziertes peptid |
| ATE494905T1 (de) * | 2001-06-29 | 2011-01-15 | Chugai Pharmaceutical Co Ltd | Krebsimpfstoff mit einem krebs-antigen auf grundlage des produkts aus dem tumorunterdrückungsgen wt1 und einem kationischen liposom |
| US7553494B2 (en) | 2001-08-24 | 2009-06-30 | Corixa Corporation | WT1 fusion proteins |
| US20050002951A1 (en) * | 2001-09-28 | 2005-01-06 | Haruo Sugiyama | Novel method of inducing antigen-specific t cells |
| JP5230891B2 (ja) | 2001-09-28 | 2013-07-10 | 株式会社癌免疫研究所 | 抗原特異的t細胞の新規な誘導方法 |
| WO2003106682A1 (ja) | 2002-06-12 | 2003-12-24 | 中外製薬株式会社 | Hla−a24拘束性癌抗原ペプチド |
| WO2004024175A1 (ja) * | 2002-09-12 | 2004-03-25 | Haruo Sugiyama | 癌抗原ペプチド製剤 |
| ES2331305T3 (es) | 2002-09-20 | 2009-12-29 | International Institute Of Cancer Immunology, Inc. | Peptidos de wt1 de tipo sustituido. |
| ES2332590T3 (es) * | 2003-01-15 | 2010-02-09 | International Institute Of Cancer Immunology, Inc. | Dimero peptidico. |
| WO2005001117A1 (ja) | 2003-06-27 | 2005-01-06 | Haruo Sugiyama | Wt1ワクチン適応患者の選択方法 |
| KR101213015B1 (ko) * | 2003-11-05 | 2012-12-26 | 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 | Wt1 로부터 유도된 hla-dr 결합성 항원 펩티드 |
| PT1731605E (pt) * | 2004-03-31 | 2010-04-14 | Int Inst Cancer Immunology Inc | Péptidos antigénicos de cancro derivados de wt1 |
| EP1951281B1 (de) | 2005-10-17 | 2015-04-15 | Sloan Kettering Institute For Cancer Research | Wt1 hla klasse ii-bindungspeptide und diese umfassende zusammensetzungen und verfahren |
| CA2631292C (en) | 2005-11-30 | 2014-05-06 | International Institute Of Cancer Immunology, Inc. | Derivatised wt1 cancer antigen peptides and their use |
| WO2007120673A2 (en) | 2006-04-10 | 2007-10-25 | Sloan Kettering Institute For Cancer Research | Immunogenic wt-1 peptides and methods of use thereof |
| GB2440528A (en) * | 2006-07-27 | 2008-02-06 | Ist Superiore Sanita | Antigen-antibody complexes |
| KR101323540B1 (ko) | 2007-02-07 | 2013-10-29 | 사이단호진한다이비세이부쯔뵤우겐큐우카이 | 암의 치료제 |
| BRPI0808084A2 (pt) | 2007-02-27 | 2014-07-22 | Int Inst Cancer Immunology Inc | Método para ativação de células t auxiliadoras e composição para uso no método. |
| KR101773690B1 (ko) | 2007-03-05 | 2017-08-31 | 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 | 암 항원 특이적 t 세포의 수용체 유전자 및 그것에 따라 코드되는 펩티드 및 이들의 사용 |
| CA2940962C (en) * | 2007-12-05 | 2018-07-24 | International Institute Of Cancer Immunology, Inc. | Cancer vaccine composition |
| KR20140009168A (ko) | 2010-10-05 | 2014-01-22 | 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 | 헬퍼 t 세포의 활성화 방법 |
| CA2839663A1 (en) | 2011-06-28 | 2013-01-03 | International Institute Of Cancer Immunology, Inc. | Receptor gene for peptide cancer antigen-specific t cell |
| US9539299B2 (en) * | 2011-10-27 | 2017-01-10 | International Institute Of Cancer Immunology, Inc. | Combination therapy with WT1 peptide vaccine and temozolomide |
| CN104080797A (zh) | 2011-11-11 | 2014-10-01 | 弗雷德哈钦森癌症研究中心 | 针对癌症的靶向细胞周期蛋白a1的t细胞免疫疗法 |
| WO2013089252A1 (ja) | 2011-12-14 | 2013-06-20 | 国立大学法人 高知大学 | ヘルパーt細胞誘導性ポリペプチドの改変 |
| AU2013207669C1 (en) | 2012-01-13 | 2018-05-31 | Memorial Sloan Kettering Cancer Center | Immunogenic WT-1 peptides and methods of use thereof |
| JP6163486B2 (ja) * | 2012-07-02 | 2017-07-12 | 大日本住友製薬株式会社 | 癌抗原ペプチド経皮剤 |
| SG10201705028WA (en) | 2012-12-17 | 2017-07-28 | Otsuka Pharma Co Ltd | Method for activating helper t cell |
| US10815273B2 (en) | 2013-01-15 | 2020-10-27 | Memorial Sloan Kettering Cancer Center | Immunogenic WT-1 peptides and methods of use thereof |
| RS61173B1 (sr) | 2013-01-15 | 2021-01-29 | Memorial Sloan Kettering Cancer Center | Imunogeni wt-1 peptidi i postupci za njihovu upotrebu |
| KR20140100419A (ko) | 2013-02-05 | 2014-08-14 | 닛토덴코 가부시키가이샤 | 경피 투여용 wt1 펩티드 암 백신 조성물 |
| CN103961697A (zh) | 2013-02-05 | 2014-08-06 | 日东电工株式会社 | 粘膜给予用疫苗组合物 |
| KR102050931B1 (ko) * | 2013-02-05 | 2019-12-02 | 닛토덴코 가부시키가이샤 | 경피 투여용 wt1 펩티드 암 백신 테이프제 |
| EP2762152A1 (de) | 2013-02-05 | 2014-08-06 | Nitto Denko Corporation | WT1-Peptidkrebsimpfstoffzusammensetzung zur transdermalen Verabreichung |
| EP2762157A1 (de) | 2013-02-05 | 2014-08-06 | Nitto Denko Corporation | Impfstoffzusammensetzung zur transdermalen oder mukosalen Verabreichung |
| RU2687026C2 (ru) | 2013-02-05 | 2019-05-06 | Нитто Денко Корпорейшн | Вакцинная композиция против злокачественной опухоли на основе пептида wt1 для мукозального введения |
| CN103961306A (zh) | 2013-02-05 | 2014-08-06 | 日东电工株式会社 | 经皮给予用疫苗组合物 |
| IN2014CH00396A (de) | 2013-02-05 | 2015-04-03 | Nitto Denko Corp | |
| EP2974734B1 (de) | 2013-03-12 | 2018-10-10 | Sumitomo Dainippon Pharma Co., Ltd. | Flüssige, wässrige zusammensetzung |
| WO2014157704A1 (ja) | 2013-03-29 | 2014-10-02 | 大日本住友製薬株式会社 | Erap1によるトリミング機能をきっかけとしたコンジュゲートワクチン |
| SG11201507883SA (en) | 2013-03-29 | 2015-10-29 | Sumitomo Dainippon Pharma Co Ltd | Wt1-antigen peptide conjugate vaccine |
| ES2841274T3 (es) | 2014-08-04 | 2021-07-07 | Hutchinson Fred Cancer Res | Inmunoterapia con células T específica para WT-1 |
| ES2916834T3 (es) | 2014-09-27 | 2022-07-06 | Sumitomo Pharma Co Ltd | Composición farmacéutica para inyección |
| JP6947720B2 (ja) * | 2015-09-10 | 2021-10-13 | メモリアル スローン ケタリング キャンサー センター | T細胞療法による多発性骨髄腫及び形質細胞白血病の治療方法 |
| SMT202200370T1 (it) | 2015-11-20 | 2022-11-18 | Memorial Sloan Kettering Cancer Center | Composizione per il trattamento del cancro |
| AU2017226956A1 (en) * | 2016-03-03 | 2018-10-11 | Institut Gustave Roussy | PTPS-based vaccines against cancer |
| US12383608B2 (en) | 2016-11-30 | 2025-08-12 | Sumitomo Pharma Co., Ltd. | WT1 helper peptides and combinations of WT1 helper peptide and conjugate of cancer antigen peptides |
| JPWO2018181648A1 (ja) | 2017-03-30 | 2020-02-13 | 大日本住友製薬株式会社 | Wt1癌抗原ペプチドおよびこれを含むペプチドコンジュゲート体 |
| AU2019218397A1 (en) | 2018-02-12 | 2020-10-01 | Fred Hutchinson Cancer Center | Cyclin A1 specific T cell receptors and uses thereof |
| JP7162675B2 (ja) | 2018-09-28 | 2022-10-28 | 住友ファーマ株式会社 | 注射用組成物 |
| CA3115240A1 (en) * | 2018-10-05 | 2020-04-09 | International Institute Of Cancer Immunology, Inc. | Composition for preventing or treating benign tumor |
| TWI875736B (zh) | 2019-02-28 | 2025-03-11 | 日商住友製藥股份有限公司 | 選擇可期待用於治療或預防癌之醫藥組合物之效果之對象之方法 |
| WO2020185796A1 (en) | 2019-03-11 | 2020-09-17 | Fred Hutchinson Cancer Research Center | High avidity wt1 t cell receptors and uses thereof |
| JP7737978B2 (ja) | 2019-08-20 | 2025-09-11 | フレッド ハッチンソン キャンサー センター | Wt-1に特異的なt細胞免疫療法 |
| MX2022007905A (es) | 2019-12-31 | 2022-08-25 | Elixirgen Therapeutics Inc | Administracion transitoria basada en temperatura de acidos nucleicos y proteinas a celulas y tejidos. |
| WO2021231376A2 (en) * | 2020-05-12 | 2021-11-18 | Cue Biopharma, Inc. | Multimeric t-cell modulatory polypeptides and methods of use thereof |
| JP7153287B2 (ja) | 2020-05-12 | 2022-10-14 | 住友ファーマ株式会社 | 癌を処置するための医薬組成物 |
| MX2024001843A (es) | 2021-08-12 | 2024-05-16 | Int Inst Cancer Immunology Inc | Composición farmacéutica y método para tratar o prevenir cáncer. |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6122018A (ja) | 1984-07-06 | 1986-01-30 | Green Cross Corp:The | 癌免疫療法増強剤 |
| JP2546254B2 (ja) | 1987-02-23 | 1996-10-23 | 澁谷工業株式会社 | ガス詰め充填装置 |
| US5726288A (en) | 1989-11-13 | 1998-03-10 | Massachusetts Institute Of Technology | Localization and characterization of the Wilms' tumor gene |
| JP3393867B2 (ja) | 1989-11-13 | 2003-04-07 | マサチユーセツツ・インステイテユート・オブ・テクノロジー | ウィルムス腫瘍遺伝子の位置決定と特徴付け |
| CA2069541C (en) * | 1992-05-26 | 2005-02-01 | Cornelis J. M. Melief | Induction of an antigen-specific t-lymphocyte response |
| EP0741580A4 (de) | 1993-12-14 | 2001-07-11 | Univ Johns Hopkins Med | Die kontrollierte freisetzung von pharmazeutisch aktiven substanzen in der immuntherapie |
| US5622835A (en) | 1994-04-28 | 1997-04-22 | The Wistar Institute Of Anatomy & Biology | WT1 monoclonal antibodies |
| EP1167379A3 (de) | 1994-07-15 | 2004-09-08 | University Of Iowa Research Foundation | Immunomodulatorische Oligonukleotide |
| US6034235A (en) | 1995-06-01 | 2000-03-07 | Tadamitsu Kishimoto | Growth inhibitor for leukemia cell comprising antisense oligonucleotide derivative to wilms tumor gene (WT1) |
| JP3904260B2 (ja) | 1995-06-01 | 2007-04-11 | 岸本 忠三 | ウイルムス腫瘍遺伝子(wt1)に対するアンチセンスオリゴヌクレオチド誘導体を含んで成る白血病細胞増殖阻害剤 |
| DE59611362D1 (de) | 1995-09-19 | 2006-08-17 | Bayer Bioscience Gmbh | Pflanzen, die eine modifizierte stärke synthetisieren, verfahren zu ihrer herstellung sowie modifizierte stärke |
| JP3060287B2 (ja) | 1995-10-09 | 2000-07-10 | 参天製薬株式会社 | アパファントを主薬とする水性点眼剤 |
| JPH09191635A (ja) | 1996-01-05 | 1997-07-22 | Toshio Aida | モータ |
| CA2243235C (en) | 1996-01-17 | 2010-08-10 | Imperial College Innovations Limited | Immunotherapy using cytotoxic t lymphocytes (ctl) |
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| US20030092656A1 (en) | 1997-07-16 | 2003-05-15 | Haruo Sugiyama | Therapeutic agents for treatment of solid tumors comprising an expression-inhibiting sustance against Wilms' tumor gene (WT1) |
| JP4789095B2 (ja) | 1997-07-16 | 2011-10-05 | 治夫 杉山 | ウイルムス腫瘍遺伝子(wt1)に対する発現阻害物質を含んで成る固形腫瘍治療剤 |
| US5985264A (en) | 1998-03-05 | 1999-11-16 | The Medical College Of Ohio | IL-12 Stimulation of Neonatal immunity |
| AU4932199A (en) | 1998-07-31 | 2000-02-21 | Haruo Sugiyama | Cancer antigens based on tumor suppressor gene wt1 product |
| US20030235557A1 (en) | 1998-09-30 | 2003-12-25 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
| US7144581B2 (en) | 2000-10-09 | 2006-12-05 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
| US20030072767A1 (en) | 1998-09-30 | 2003-04-17 | Alexander Gaiger | Compositions and methods for WT1 specific immunotherapy |
| AR021849A1 (es) | 1998-09-30 | 2002-08-07 | Corixa Corp | Composiciones y metodos para la inmunoterapia especifica de wt1 |
| US7655249B2 (en) | 1998-09-30 | 2010-02-02 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
| US20030039635A1 (en) | 1998-09-30 | 2003-02-27 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
| US7901693B2 (en) | 1998-09-30 | 2011-03-08 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
| US20030215458A1 (en) | 1998-09-30 | 2003-11-20 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
| US7063854B1 (en) * | 1998-09-30 | 2006-06-20 | Corixa Corporation | Composition and methods for WTI specific immunotherapy |
| GB9823897D0 (en) * | 1998-11-02 | 1998-12-30 | Imp College Innovations Ltd | Immunotherapeutic methods and molecules |
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