DK1103564T3 - Cancerantigener baseret på tumorsuppressorgen WT1-produkt - Google Patents
Cancerantigener baseret på tumorsuppressorgen WT1-produktInfo
- Publication number
- DK1103564T3 DK1103564T3 DK99933205T DK99933205T DK1103564T3 DK 1103564 T3 DK1103564 T3 DK 1103564T3 DK 99933205 T DK99933205 T DK 99933205T DK 99933205 T DK99933205 T DK 99933205T DK 1103564 T3 DK1103564 T3 DK 1103564T3
- Authority
- DK
- Denmark
- Prior art keywords
- product
- tumor suppressor
- suppressor gene
- cancer antigens
- antigens based
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 108700025716 Tumor Suppressor Genes Proteins 0.000 title 1
- 102000044209 Tumor Suppressor Genes Human genes 0.000 title 1
- 239000000427 antigen Substances 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001152—Transcription factors, e.g. SOX or c-MYC
- A61K39/001153—Wilms tumor 1 [WT1]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4242—Transcription factors, e.g. SOX or c-MYC
- A61K40/4243—Wilms tumor 1 [WT1]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP21809398 | 1998-07-31 | ||
| PCT/JP1999/004130 WO2000006602A1 (fr) | 1998-07-31 | 1999-07-30 | Antigenes contre le cancer a base d'un produit du gene suppresseur de tumeur wt1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1103564T3 true DK1103564T3 (da) | 2009-05-11 |
Family
ID=16714530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99933205T DK1103564T3 (da) | 1998-07-31 | 1999-07-30 | Cancerantigener baseret på tumorsuppressorgen WT1-produkt |
Country Status (15)
| Country | Link |
|---|---|
| US (7) | US7030212B1 (de) |
| EP (3) | EP1103564B1 (de) |
| JP (2) | JP4422903B2 (de) |
| KR (1) | KR100767554B1 (de) |
| CN (4) | CN1560078B (de) |
| AT (1) | ATE420112T1 (de) |
| AU (1) | AU4932199A (de) |
| BR (1) | BRPI9912663B8 (de) |
| CA (1) | CA2337743C (de) |
| DE (1) | DE69940264D1 (de) |
| DK (1) | DK1103564T3 (de) |
| ES (1) | ES2318898T3 (de) |
| HK (1) | HK1038929B (de) |
| PT (1) | PT1103564E (de) |
| WO (1) | WO2000006602A1 (de) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2203782T3 (es) | 1996-01-17 | 2004-04-16 | Imperial College Innovations Limited | Inmunoterapia que utiliza linfocitos t citotoxicos (ctl). |
| CN1560078B (zh) | 1998-07-31 | 2011-06-22 | 株式会社国际癌症免疫研究所 | 基于癌抑制基因wt1的产物的癌抗原 |
| US7329410B1 (en) | 1998-09-30 | 2008-02-12 | Corixa Corporation | Compositions and method for WT1 specific immunotherapy |
| US7063854B1 (en) | 1998-09-30 | 2006-06-20 | Corixa Corporation | Composition and methods for WTI specific immunotherapy |
| US7901693B2 (en) | 1998-09-30 | 2011-03-08 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
| US7144581B2 (en) | 2000-10-09 | 2006-12-05 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
| US7115272B1 (en) | 1998-09-30 | 2006-10-03 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
| ATE399179T1 (de) * | 1998-09-30 | 2008-07-15 | Corixa Corp | Zusammensetzungen und verfahren für wt1- spezifische immunotherapie |
| US7655249B2 (en) | 1998-09-30 | 2010-02-02 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
| GB9823897D0 (en) | 1998-11-02 | 1998-12-30 | Imp College Innovations Ltd | Immunotherapeutic methods and molecules |
| AU7859900A (en) * | 1999-10-04 | 2001-05-10 | Corixa Corporation | Compositions and methods for wt1 specific immunotherapy |
| CA2401070A1 (en) * | 2000-02-22 | 2001-08-30 | Corixa Corporation | Compositions and methods for diagnosis and therapy of malignant mesothelioma |
| ES2298353T3 (es) * | 2001-03-22 | 2008-05-16 | International Institute Of Cancer Immunology, Inc. | Peptido wt1 modificado. |
| CN1320923C (zh) * | 2001-06-29 | 2007-06-13 | 中外制药株式会社 | 含有基于癌抑制基因wt1的产物的癌抗原和阳离子脂质体的癌疫苗 |
| US7553494B2 (en) | 2001-08-24 | 2009-06-30 | Corixa Corporation | WT1 fusion proteins |
| US20050002951A1 (en) * | 2001-09-28 | 2005-01-06 | Haruo Sugiyama | Novel method of inducing antigen-specific t cells |
| US8735357B2 (en) | 2001-09-28 | 2014-05-27 | International Institute Of Cancer Immunology, Inc. | Method of inducing antigen-specific T cells |
| WO2003106682A1 (ja) | 2002-06-12 | 2003-12-24 | 中外製薬株式会社 | Hla−a24拘束性癌抗原ペプチド |
| WO2004024175A1 (ja) * | 2002-09-12 | 2004-03-25 | Haruo Sugiyama | 癌抗原ペプチド製剤 |
| ATE442378T1 (de) | 2002-09-20 | 2009-09-15 | Int Inst Cancer Immunology Inc | Substituierte wt1-peptide |
| EP1584627B1 (de) | 2003-01-15 | 2009-10-07 | International Institute of Cancer Immunology, Inc. | Dimerisiertes peptid |
| KR101431312B1 (ko) | 2003-06-27 | 2014-08-20 | 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 | Wt1 백신 적응 환자의 선택 방법 |
| CN101580538B (zh) | 2003-11-05 | 2013-06-19 | 株式会社国际癌症免疫研究所 | Wt1衍生的hla-dr-结合抗原肽 |
| ES2556232T3 (es) * | 2004-03-31 | 2016-01-14 | International Institute Of Cancer Immunology, Inc. | Péptidos antigénicos del cáncer derivados de WT1 |
| ES2542141T3 (es) | 2005-10-17 | 2015-07-31 | Sloan Kettering Institute For Cancer Research | Péptidos WT1 de unión a HLA de clase II, y composiciones y métodos que los comprenden |
| ES2352855T3 (es) | 2005-11-30 | 2011-02-23 | International Institute Of Cancer Immunology, Inc. | Nuevos compuestos peptídicos del tumor de wilms. |
| PL2010209T3 (pl) | 2006-04-10 | 2017-04-28 | Sloan Kettering Inst For Cancer Res | Immunogeniczne peptydy WT-1 i sposoby ich użycia |
| GB2440528A (en) * | 2006-07-27 | 2008-02-06 | Ist Superiore Sanita | Antigen-antibody complexes |
| US9045556B2 (en) | 2007-02-07 | 2015-06-02 | Nec Corporation | Therapeutic agent for cancer |
| MX2009009168A (es) | 2007-02-27 | 2009-09-07 | Int Inst Cancer Immunology Inc | Metodo para activacion de celula t auxiliar y composicion para usarse en el metodo. |
| EP3173480A3 (de) | 2007-03-05 | 2017-08-16 | International Institute of Cancer Immunology, Inc. | Krebs-antigen-spezifisches t-zell-rezeptorgen, durch das gen codiertes peptid und verwendung davon |
| ES2679127T3 (es) * | 2007-12-05 | 2018-08-22 | International Institute Of Cancer Immunology, Inc. | Composición vacunal contra el cáncer |
| SG189287A1 (en) | 2010-10-05 | 2013-05-31 | Int Inst Cancer Immunology Inc | Method for activating helper t cell |
| KR20140039318A (ko) | 2011-06-28 | 2014-04-01 | 인터내셔널 인스티튜트 오브 캔서 이무놀로지 인코퍼레이티드 | 펩티드 암 항원 특이적 t 세포의 리셉터 유전자 |
| US9539299B2 (en) * | 2011-10-27 | 2017-01-10 | International Institute Of Cancer Immunology, Inc. | Combination therapy with WT1 peptide vaccine and temozolomide |
| KR102134932B1 (ko) | 2011-11-11 | 2020-07-17 | 프레드 헛친슨 켄서 리서치 센터 | 암을 위한 사이클린 a1―표적화된 t―세포 면역요법 |
| JP6218175B2 (ja) * | 2011-12-14 | 2017-10-25 | 国立大学法人高知大学 | ヘルパーt細胞誘導性ポリペプチドの改変 |
| CA2861206C (en) | 2012-01-13 | 2021-07-06 | Richard J. O'reilly | Immunogenic wt-1 peptides and methods of use thereof |
| EP2868325B1 (de) * | 2012-07-02 | 2017-11-01 | Sumitomo Dainippon Pharma Co., Ltd. | Transdermales krebs-antigen-peptidpräparat |
| WO2014098012A1 (ja) | 2012-12-17 | 2014-06-26 | 大塚製薬株式会社 | ヘルパーt細胞の活性化方法 |
| US10815273B2 (en) | 2013-01-15 | 2020-10-27 | Memorial Sloan Kettering Cancer Center | Immunogenic WT-1 peptides and methods of use thereof |
| EP3769782A1 (de) | 2013-01-15 | 2021-01-27 | Memorial Sloan Kettering Cancer Center | Immunogene wt-1-peptide und verfahren zur verwendung davon |
| JP6497691B2 (ja) | 2013-02-05 | 2019-04-10 | 日東電工株式会社 | 粘膜投与用wt1ペプチド癌ワクチン組成物 |
| EP2762154A3 (de) | 2013-02-05 | 2015-01-21 | Nitto Denko Corporation | Impfstoff zur transdermalen Verabreichung |
| RU2014102941A (ru) | 2013-02-05 | 2015-08-10 | Нитто Денко Корпорейшн | Вакцинная композиция для введения через слизистую оболочку |
| IN2014CH00395A (de) | 2013-02-05 | 2015-04-03 | Nitto Denko Corp | |
| EP2762152A1 (de) | 2013-02-05 | 2014-08-06 | Nitto Denko Corporation | WT1-Peptidkrebsimpfstoffzusammensetzung zur transdermalen Verabreichung |
| KR102050931B1 (ko) | 2013-02-05 | 2019-12-02 | 닛토덴코 가부시키가이샤 | 경피 투여용 wt1 펩티드 암 백신 테이프제 |
| KR20140100419A (ko) | 2013-02-05 | 2014-08-14 | 닛토덴코 가부시키가이샤 | 경피 투여용 wt1 펩티드 암 백신 조성물 |
| EP3662927A3 (de) | 2013-02-05 | 2020-10-21 | Nitto Denko Corporation | Impfstoffzusammensetzung |
| US9663563B2 (en) | 2013-03-12 | 2017-05-30 | Sumitomo Dainippon Pharma Co., Ltd. | Aqueous liquid composition |
| EP2980097A4 (de) | 2013-03-29 | 2017-03-08 | Sumitomo Dainippon Pharma Co., Ltd. | Konjugatimpfstoff mit trimmfunktion von erap1 |
| MY171854A (en) | 2013-03-29 | 2019-11-05 | Sumitomo Dainippon Pharma Co Ltd | Wt1 antigen peptide conjugate vaccine |
| CN107074970B (zh) | 2014-08-04 | 2021-07-30 | 弗雷德哈钦森癌症研究中心 | 特异性针对wt-1的t细胞免疫疗法 |
| JP6580581B2 (ja) | 2014-09-27 | 2019-09-25 | 大日本住友製薬株式会社 | 注射用医薬組成物 |
| KR20180048992A (ko) * | 2015-09-10 | 2018-05-10 | 메모리얼 슬로안-케터링 캔서 센터 | T 세포 요법에 의해 다발성 골수종 및 형질 세포성 백혈병을 치료하는 방법 |
| LT3377516T (lt) | 2015-11-20 | 2022-09-26 | Memorial Sloan Kettering Cancer Center | Kompozicija vėžiui gydyti |
| US20190091307A1 (en) * | 2016-03-03 | 2019-03-28 | Institut Gustave Roussy | Ptps-based vaccines against cancer |
| EP3549957A4 (de) | 2016-11-30 | 2020-08-05 | Sumitomo Dainippon Pharma Co., Ltd. | Wt1-helferpeptid und kombination des besagten peptids und eines krebsantigen-peptidkonjugats |
| EP3604325A4 (de) | 2017-03-30 | 2021-01-13 | Sumitomo Dainippon Pharma Co., Ltd. | Wt1-krebs-antigen-peptid und peptid-konjugat-körper damit |
| CN112004825A (zh) | 2018-02-12 | 2020-11-27 | 弗雷德哈钦森癌症研究中心 | 细胞周期蛋白a1特异性t细胞受体及其用途 |
| MX2021003660A (es) | 2018-09-28 | 2021-05-28 | Sumitomo Pharma Co Ltd | Composicion inyectable. |
| AU2019352354B2 (en) * | 2018-10-05 | 2025-07-03 | International Institute Of Cancer Immunology, Inc. | Prophylactic or therapeutic drug for benign tumor |
| TWI875736B (zh) | 2019-02-28 | 2025-03-11 | 日商住友製藥股份有限公司 | 選擇可期待用於治療或預防癌之醫藥組合物之效果之對象之方法 |
| CN113784978B (zh) | 2019-03-11 | 2025-07-25 | 弗雷德哈钦森癌症中心 | 高亲合力wt1 t细胞受体及其用途 |
| JP7737978B2 (ja) | 2019-08-20 | 2025-09-11 | フレッド ハッチンソン キャンサー センター | Wt-1に特異的なt細胞免疫療法 |
| WO2021138447A1 (en) | 2019-12-31 | 2021-07-08 | Elixirgen Therapeutics, Inc. | Temperature-based transient delivery of nucleic acids and proteins to cells and tissues |
| TW202208395A (zh) * | 2020-05-12 | 2022-03-01 | 美商信號生物製藥公司 | 多聚體t細胞調節多肽及其使用方法 |
| WO2021230247A1 (ja) | 2020-05-12 | 2021-11-18 | 大日本住友製薬株式会社 | 癌を処置するための医薬組成物 |
| AU2022327884A1 (en) | 2021-08-12 | 2024-02-22 | International Institute Of Cancer Immunology, Inc. | Pharmaceutical composition and method for treatment or prevention of cancer |
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| US20030215458A1 (en) | 1998-09-30 | 2003-11-20 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
| US7063854B1 (en) * | 1998-09-30 | 2006-06-20 | Corixa Corporation | Composition and methods for WTI specific immunotherapy |
| US7901693B2 (en) | 1998-09-30 | 2011-03-08 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
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| ATE399179T1 (de) | 1998-09-30 | 2008-07-15 | Corixa Corp | Zusammensetzungen und verfahren für wt1- spezifische immunotherapie |
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1999
- 1999-07-30 CN CN2004100492708A patent/CN1560078B/zh not_active Expired - Lifetime
- 1999-07-30 ES ES99933205T patent/ES2318898T3/es not_active Expired - Lifetime
- 1999-07-30 EP EP99933205A patent/EP1103564B1/de not_active Expired - Lifetime
- 1999-07-30 CN CNB998102091A patent/CN1178956C/zh not_active Expired - Lifetime
- 1999-07-30 DK DK99933205T patent/DK1103564T3/da active
- 1999-07-30 CN CN2011101028829A patent/CN102198266A/zh active Pending
- 1999-07-30 HK HK02100403.9A patent/HK1038929B/zh not_active IP Right Cessation
- 1999-07-30 AU AU49321/99A patent/AU4932199A/en not_active Abandoned
- 1999-07-30 US US09/744,815 patent/US7030212B1/en not_active Expired - Lifetime
- 1999-07-30 EP EP09000053.0A patent/EP2048160B1/de not_active Expired - Lifetime
- 1999-07-30 DE DE69940264T patent/DE69940264D1/de not_active Expired - Lifetime
- 1999-07-30 JP JP2000562398A patent/JP4422903B2/ja not_active Expired - Lifetime
- 1999-07-30 PT PT99933205T patent/PT1103564E/pt unknown
- 1999-07-30 CN CNB2005100995114A patent/CN100560130C/zh not_active Expired - Lifetime
- 1999-07-30 KR KR1020017001272A patent/KR100767554B1/ko not_active Expired - Lifetime
- 1999-07-30 WO PCT/JP1999/004130 patent/WO2000006602A1/ja not_active Ceased
- 1999-07-30 BR BRPI9912663-0 patent/BRPI9912663B8/pt unknown
- 1999-07-30 AT AT99933205T patent/ATE420112T1/de active
- 1999-07-30 EP EP10013059.0A patent/EP2280031B1/de not_active Expired - Lifetime
- 1999-07-30 CA CA2337743A patent/CA2337743C/en not_active Expired - Lifetime
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2005
- 2005-08-04 US US11/196,459 patent/US7390871B2/en not_active Expired - Lifetime
- 2005-08-04 US US11/196,452 patent/US7608685B1/en not_active Expired - Fee Related
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2006
- 2006-01-03 US US11/322,245 patent/US7517950B2/en not_active Expired - Fee Related
-
2008
- 2008-07-29 US US12/181,938 patent/US9403886B2/en not_active Expired - Fee Related
-
2009
- 2009-02-05 US US12/366,200 patent/US7807792B2/en not_active Expired - Fee Related
- 2009-10-30 JP JP2009251079A patent/JP5230579B2/ja not_active Expired - Lifetime
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2016
- 2016-04-05 US US15/091,111 patent/US20160243209A1/en not_active Abandoned
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