ATE426817T1 - Verfahren zur identifizierung von proteinfaltungsinhibitoren - Google Patents

Verfahren zur identifizierung von proteinfaltungsinhibitoren

Info

Publication number
ATE426817T1
ATE426817T1 AT06762655T AT06762655T ATE426817T1 AT E426817 T1 ATE426817 T1 AT E426817T1 AT 06762655 T AT06762655 T AT 06762655T AT 06762655 T AT06762655 T AT 06762655T AT E426817 T1 ATE426817 T1 AT E426817T1
Authority
AT
Austria
Prior art keywords
protein folding
identifying protein
inhibitors
folding inhibitors
relates
Prior art date
Application number
AT06762655T
Other languages
English (en)
Inventor
Ricardo Broglia
Guido Tiana
Original Assignee
Univ Degli Studi Milano
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Degli Studi Milano filed Critical Univ Degli Studi Milano
Application granted granted Critical
Publication of ATE426817T1 publication Critical patent/ATE426817T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Obesity (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
AT06762655T 2005-07-19 2006-07-17 Verfahren zur identifizierung von proteinfaltungsinhibitoren ATE426817T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20050015597 EP1746422A1 (de) 2005-07-19 2005-07-19 Verfahren zur Identifizierung von Inhibitoren der Faltung der Proteine

Publications (1)

Publication Number Publication Date
ATE426817T1 true ATE426817T1 (de) 2009-04-15

Family

ID=34937871

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06762655T ATE426817T1 (de) 2005-07-19 2006-07-17 Verfahren zur identifizierung von proteinfaltungsinhibitoren

Country Status (12)

Country Link
US (1) US20080199965A1 (de)
EP (2) EP1746422A1 (de)
JP (1) JP5280202B2 (de)
CN (1) CN101228443B (de)
AT (1) ATE426817T1 (de)
BR (1) BRPI0613417A2 (de)
CA (1) CA2614236A1 (de)
DE (1) DE602006005932D1 (de)
ES (1) ES2323654T3 (de)
PT (1) PT1904854E (de)
WO (1) WO2007009727A1 (de)
ZA (1) ZA200800267B (de)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999040435A1 (en) * 1998-02-09 1999-08-12 Netzer William J Protein folding inhibitors
WO2001034631A2 (en) * 1999-11-05 2001-05-17 Axonyx, Inc. PEPTIDE ANALOGS AND MIMETICS SUITABLE FOR IN VIVO USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH ABNORMAL PROTEIN FOLDING INTO AMYLOID, AMYLOID-LIKE DEPOSITS OR β-SHEET RICH PATHOLOGICAL PRECURSOR THEREOF
US6689753B1 (en) * 1999-11-05 2004-02-10 Axonyx, Inc. β sheet breaker peptide analogs that inhibit β pleated sheet formation in amyloid β-peptide

Also Published As

Publication number Publication date
JP2009501535A (ja) 2009-01-22
EP1904854B1 (de) 2009-03-25
EP1904854A1 (de) 2008-04-02
CN101228443B (zh) 2013-03-27
EP1904854B9 (de) 2009-12-16
EP1746422A1 (de) 2007-01-24
US20080199965A1 (en) 2008-08-21
JP5280202B2 (ja) 2013-09-04
BRPI0613417A2 (pt) 2011-01-11
HK1115918A1 (en) 2008-12-12
ES2323654T3 (es) 2009-07-22
CN101228443A (zh) 2008-07-23
CA2614236A1 (en) 2007-01-25
WO2007009727A1 (en) 2007-01-25
PT1904854E (pt) 2009-07-01
ZA200800267B (en) 2009-04-29
DE602006005932D1 (de) 2009-05-07

Similar Documents

Publication Publication Date Title
DE602005021336D1 (de) Verfahren zur identifizierung von proteinen mit stärkephosphorylierender enzymatischer aktivität
ATE540114T1 (de) Verfahren und zusammensetzungen zur schnellen isolierung kleiner rna-moleküle
ATE466080T1 (de) Formulierungen und verfahren zum denaturieren von proteinen
ATE545712T1 (de) Verfahren mit verwendung von poren
DE60330842D1 (de) Für den nachweis von nukleinsäuren kompetente biologische rohderivate
DK1534830T3 (da) In vito-peptid-ekspressionsbibliotek
ATE348881T1 (de) Thermostabiles taq polymerase fragment
ATE474847T1 (de) Verfahren zur herstellung von dipeptiden
ATE393237T1 (de) Mittel und verfahren zur in-vitro-bestimmung von camp
ATE416619T1 (de) Verfahren zur dearomatisierung von molkeprotein
DE60323579D1 (de) Methode zur Separierung von Nukleinsäuren und dafür verwendbare Reagenz
ATE487792T1 (de) Verfahren und zusammensetzungen zur identifikation von rna-bindenden proteinen
ATE506370T1 (de) Reagenzien und verfahren zur bildung von disulfid-bindungen und glykosylierung von proteinen
DE50207801D1 (de) Verfahren zum Nachweis prokaryontischer DNA
ATE533837T1 (de) Microginin-produzierende proteine und nukleinsäuren, einen microginin gen-cluster kodierend, sowie methoden zur herstellung von microgininen
ATE383418T1 (de) Verfahren und zusammensetzungen zur bestimmung glycierter proteine
ATE426817T1 (de) Verfahren zur identifizierung von proteinfaltungsinhibitoren
ATE452984T1 (de) Verfahren und zusammensetzungen zur extraktion von proteinen aus zellen
WO2006079334A3 (de) Verfahren zu nachweis und quantifizierung von proteinen unter verwendung von farbstoffen auf der basis von polymethinen
ATE547161T1 (de) Verfahren zur quantitativen bestimmung von poloxameren
DE60218848D1 (de) Verfahren zur trennung und/oder zum nachweis und/oder zur identifizierung und/oder zur quantifizierung von prionproteinen
ATE421733T1 (de) Methode zur identifizierung von unbekannten proteinen mittels zwei-dimensionaler auftrennung und verwendung von markern
WO2006094185A3 (en) Quantification of proteins
WO2004094989A3 (en) Methods of host cell protein analysis
ATE421698T1 (de) Intrinsic-faktor vom schwein

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties