ATE429930T1 - Verfahren zur förderung des nukleinsäuretransfers - Google Patents
Verfahren zur förderung des nukleinsäuretransfersInfo
- Publication number
- ATE429930T1 ATE429930T1 AT02741206T AT02741206T ATE429930T1 AT E429930 T1 ATE429930 T1 AT E429930T1 AT 02741206 T AT02741206 T AT 02741206T AT 02741206 T AT02741206 T AT 02741206T AT E429930 T1 ATE429930 T1 AT E429930T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- cells
- complex particles
- gene
- protein
- Prior art date
Links
- 108020004707 nucleic acids Proteins 0.000 title abstract 13
- 102000039446 nucleic acids Human genes 0.000 title abstract 13
- 150000007523 nucleic acids Chemical class 0.000 title abstract 13
- 238000000034 method Methods 0.000 title abstract 6
- 230000001737 promoting effect Effects 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 9
- 239000002245 particle Substances 0.000 abstract 8
- 102000008186 Collagen Human genes 0.000 abstract 4
- 108010035532 Collagen Proteins 0.000 abstract 4
- 229920001436 collagen Polymers 0.000 abstract 4
- 230000014509 gene expression Effects 0.000 abstract 4
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 238000012258 culturing Methods 0.000 abstract 3
- 201000010099 disease Diseases 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 239000007790 solid phase Substances 0.000 abstract 3
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 230000035755 proliferation Effects 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/6435—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a connective tissue peptide, e.g. collagen, fibronectin or gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001186320 | 2001-06-20 | ||
| JP2001278293 | 2001-09-13 | ||
| PCT/JP2002/006137 WO2003000297A1 (fr) | 2001-06-20 | 2002-06-20 | Procede facilitant le transfert d'acides nucleiques |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE429930T1 true ATE429930T1 (de) | 2009-05-15 |
Family
ID=26617260
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02741206T ATE429930T1 (de) | 2001-06-20 | 2002-06-20 | Verfahren zur förderung des nukleinsäuretransfers |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US8742091B2 (de) |
| EP (1) | EP1407787B1 (de) |
| JP (1) | JP4081436B2 (de) |
| KR (1) | KR100888566B1 (de) |
| CN (1) | CN1313158C (de) |
| AT (1) | ATE429930T1 (de) |
| CA (1) | CA2451603C (de) |
| DE (1) | DE60232149D1 (de) |
| DK (1) | DK1407787T3 (de) |
| ES (1) | ES2324525T3 (de) |
| PT (1) | PT1407787E (de) |
| WO (1) | WO2003000297A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040052840A1 (en) * | 2000-06-20 | 2004-03-18 | Shunichiro Kubota | Preparations for oligonucleotide transfer |
| ATE429930T1 (de) | 2001-06-20 | 2009-05-15 | Dainippon Sumitomo Pharma Co | Verfahren zur förderung des nukleinsäuretransfers |
| US20080318319A1 (en) * | 2003-12-19 | 2008-12-25 | Yoshiko Minakuchi | Novel Method of Nucleic Acid Transfer |
| US20080038824A1 (en) * | 2004-01-29 | 2008-02-14 | National Institute Of Advanced Industrial Science And Technology | Composition and Method for Elevating Gene Transfer Efficiency |
| JP2007267602A (ja) * | 2004-06-25 | 2007-10-18 | National Institute Of Advanced Industrial & Technology | 固相上で細胞に核酸を導入し、かつ、この細胞を分化誘導させるための方法および組成物 |
| JP4585242B2 (ja) * | 2004-06-29 | 2010-11-24 | 株式会社高研 | 核酸導入用セルトランスフェクションアレイ |
| US20090062184A1 (en) * | 2005-03-24 | 2009-03-05 | Dainippon Sumitomo Pharma Co., Ltd. | Fine particulate preparation comprising complex of nucleic acid molecule and collagen |
| US7838502B2 (en) * | 2005-05-06 | 2010-11-23 | University Of Massachusetts Medical School | Compositions and methods to modulate H. influenzae pathogenesis |
| WO2006126600A1 (ja) * | 2005-05-25 | 2006-11-30 | National University Corporation Nagoya Universtiy | 血管閉塞性疾患用医薬組成物 |
| WO2007010620A1 (ja) | 2005-07-22 | 2007-01-25 | Koken Co., Ltd. | 核酸導入用セルトランスフェクションアレイ |
| WO2007107774A2 (en) * | 2006-03-22 | 2007-09-27 | Cartela R & D Ab | Integrin alpha-10 subunit as therapeutic target and diagnostic/prognostic marker for cancer |
| EP2127681A4 (de) * | 2007-02-16 | 2011-10-12 | Anges Mg Inc | Therapeutisches mittel gegen parodontalerkrankungen und alveolar-knochenverlust durch operation |
| JP5789927B2 (ja) * | 2010-07-30 | 2015-10-07 | Jnc株式会社 | 放射線照射コラーゲン様ペプチドを用いた核酸導入法 |
| WO2013102878A2 (en) | 2012-01-05 | 2013-07-11 | Department Of Biotechnology (Dbt) | Fat1 gene in cancer and inflammation |
| US12433937B2 (en) | 2019-08-30 | 2025-10-07 | University Of Florida Research Foundation, Inc. | Aptamer assemblies for protein crosslinking |
| WO2022120338A1 (en) * | 2020-12-03 | 2022-06-09 | University Of Florida Research Foundation, Inc. | Aptamer assemblies for protein crosslinking |
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| US5069936A (en) * | 1987-06-25 | 1991-12-03 | Yen Richard C K | Manufacturing protein microspheres |
| JPS6416581A (en) | 1987-07-09 | 1989-01-20 | Rikagaku Kenkyusho | Frozen animal cell and production thereof |
| JPH01157388A (ja) | 1987-12-11 | 1989-06-20 | Mitsubishi Heavy Ind Ltd | 形質転換方法 |
| US5078997A (en) | 1988-07-13 | 1992-01-07 | Cetus Corporation | Pharmaceutical composition for interleukin-2 containing physiologically compatible stabilizers |
| US5098890A (en) * | 1988-11-07 | 1992-03-24 | Temple University-Of The Commonwealth System Of Higher Education | Antisence oligonucleotides to c-myb proto-oncogene and uses thereof |
| US5614587A (en) | 1988-11-21 | 1997-03-25 | Collagen Corporation | Collagen-based bioadhesive compositions |
| US5936035A (en) | 1988-11-21 | 1999-08-10 | Cohesion Technologies, Inc. | Biocompatible adhesive compositions |
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| FR2694895B1 (fr) * | 1992-08-20 | 1994-11-10 | Coletica | Procédé de fabrication de microparticules en émulsion par modification de la composition chimique de la phase dispersée après émulsification. |
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| ATE429930T1 (de) | 2001-06-20 | 2009-05-15 | Dainippon Sumitomo Pharma Co | Verfahren zur förderung des nukleinsäuretransfers |
| JP4022614B2 (ja) | 2002-03-25 | 2007-12-19 | 国立大学法人大阪大学 | 新規なバイオビーズの作製方法 |
| ITMI20021444A1 (it) | 2002-07-01 | 2004-01-02 | Danieli Off Mecc | Tubo forma spire |
| US7148342B2 (en) | 2002-07-24 | 2006-12-12 | The Trustees Of The University Of Pennyslvania | Compositions and methods for sirna inhibition of angiogenesis |
| EP1551424B1 (de) | 2002-09-04 | 2015-07-01 | Arrowhead Research Corporation | Behandlung von chronisch neuropathischen schmerzen durch verabreichung von dsrna |
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| WO2004042024A2 (en) | 2002-11-01 | 2004-05-21 | The Trustees Of The University Of Pennsylvania | COMPOSITIONS AND METHODS FOR siRNA INHIBITION OF HIF-1 ALPHA |
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| DK1720893T3 (en) | 2004-02-26 | 2014-11-24 | Baylor Res Inst | COMPOSITIONS AND PROCEDURES FOR THE SYSTEMIC TREATMENT OF ARTHRITIS |
| JP4991547B2 (ja) | 2004-09-28 | 2012-08-01 | クアーク・ファーマスーティカルス、インコーポレイテッド | 脱毛症、急性腎不全および他の疾患の治療のためのオリゴリボヌクレオチドおよびその使用の方法 |
| AU2005297354A1 (en) | 2004-10-22 | 2006-04-27 | The Hospital For Sick Children | Modulation of neuroglia-derived BDNF in the treatment and prevention of pain |
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| BRPI0714875A2 (pt) | 2006-07-21 | 2013-05-28 | Silence Therapeutics Ag | meios para inibir a expressço da proteÍna cinase 3 |
| WO2008028085A2 (en) | 2006-08-30 | 2008-03-06 | The Board Of Trustees Of The University Of Illinois | Modulation of mlck-l expression and uses thereof |
| AU2007302803A1 (en) | 2006-10-02 | 2008-04-10 | Aprea Ab | RNA interference against Wrap53 to treat hyperproliferative diseases |
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| US8227444B2 (en) | 2009-12-04 | 2012-07-24 | Opko Ophthalmics, Llc | Compositions and methods for inhibition of VEGF |
-
2002
- 2002-06-20 AT AT02741206T patent/ATE429930T1/de active
- 2002-06-20 CA CA2451603A patent/CA2451603C/en not_active Expired - Fee Related
- 2002-06-20 CN CNB028164008A patent/CN1313158C/zh not_active Expired - Fee Related
- 2002-06-20 EP EP02741206A patent/EP1407787B1/de not_active Expired - Lifetime
- 2002-06-20 US US10/481,511 patent/US8742091B2/en not_active Expired - Fee Related
- 2002-06-20 WO PCT/JP2002/006137 patent/WO2003000297A1/ja not_active Ceased
- 2002-06-20 PT PT02741206T patent/PT1407787E/pt unknown
- 2002-06-20 KR KR1020037016627A patent/KR100888566B1/ko not_active Expired - Fee Related
- 2002-06-20 DK DK02741206T patent/DK1407787T3/da active
- 2002-06-20 DE DE60232149T patent/DE60232149D1/de not_active Expired - Lifetime
- 2002-06-20 JP JP2003506939A patent/JP4081436B2/ja not_active Expired - Lifetime
- 2002-06-20 ES ES02741206T patent/ES2324525T3/es not_active Expired - Lifetime
-
2009
- 2009-09-04 US US12/554,846 patent/US20100081202A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PT1407787E (pt) | 2009-07-07 |
| DK1407787T3 (da) | 2009-06-02 |
| EP1407787A4 (de) | 2006-02-08 |
| CA2451603A1 (en) | 2003-01-03 |
| US20040266004A1 (en) | 2004-12-30 |
| CN1313158C (zh) | 2007-05-02 |
| US20100081202A1 (en) | 2010-04-01 |
| EP1407787A1 (de) | 2004-04-14 |
| EP1407787B1 (de) | 2009-04-29 |
| JPWO2003000297A1 (ja) | 2005-04-07 |
| WO2003000297A1 (fr) | 2003-01-03 |
| CN1622831A (zh) | 2005-06-01 |
| CA2451603C (en) | 2012-07-10 |
| US8742091B2 (en) | 2014-06-03 |
| KR20040023622A (ko) | 2004-03-18 |
| ES2324525T3 (es) | 2009-08-10 |
| DE60232149D1 (de) | 2009-06-10 |
| JP4081436B2 (ja) | 2008-04-23 |
| KR100888566B1 (ko) | 2009-03-12 |
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