ATE431739T1 - Pharmazeutische zusammensetzung enthaltend stabilisierte amorphe form von donepezil hydrochlorid - Google Patents

Pharmazeutische zusammensetzung enthaltend stabilisierte amorphe form von donepezil hydrochlorid

Info

Publication number
ATE431739T1
ATE431739T1 AT03741747T AT03741747T ATE431739T1 AT E431739 T1 ATE431739 T1 AT E431739T1 AT 03741747 T AT03741747 T AT 03741747T AT 03741747 T AT03741747 T AT 03741747T AT E431739 T1 ATE431739 T1 AT E431739T1
Authority
AT
Austria
Prior art keywords
amorphous form
pharmaceutical composition
donepezil hydrochloride
composition containing
containing stabilized
Prior art date
Application number
AT03741747T
Other languages
English (en)
Inventor
Miha Vrbinc
Kolar Alesa Puncuh
Franc Vrecer
Jordan Berta Kotar
Veronika Stangelj
Original Assignee
Krka Tovarna Zdravil D D Novo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Krka Tovarna Zdravil D D Novo filed Critical Krka Tovarna Zdravil D D Novo
Application granted granted Critical
Publication of ATE431739T1 publication Critical patent/ATE431739T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
AT03741747T 2002-06-19 2003-06-18 Pharmazeutische zusammensetzung enthaltend stabilisierte amorphe form von donepezil hydrochlorid ATE431739T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SI200200155A SI21223A (sl) 2002-06-19 2002-06-19 Farmacevtska formulacija s stabiliziranim amorfnim donepezilijevim kloridom
PCT/SI2003/000019 WO2004000317A1 (en) 2002-06-19 2003-06-18 Pharmaceutical composition containing stabilised amorphous form of donepezil hydrochloride

Publications (1)

Publication Number Publication Date
ATE431739T1 true ATE431739T1 (de) 2009-06-15

Family

ID=29778199

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03741747T ATE431739T1 (de) 2002-06-19 2003-06-18 Pharmazeutische zusammensetzung enthaltend stabilisierte amorphe form von donepezil hydrochlorid

Country Status (15)

Country Link
EP (1) EP1513528B1 (de)
AT (1) ATE431739T1 (de)
AU (1) AU2003279102A1 (de)
CY (1) CY1109314T1 (de)
DE (1) DE60327696D1 (de)
DK (1) DK1513528T3 (de)
EA (1) EA012904B1 (de)
ES (1) ES2326529T3 (de)
HR (1) HRP20041198B1 (de)
PL (1) PL212584B1 (de)
PT (1) PT1513528E (de)
RS (1) RS51824B (de)
SI (2) SI21223A (de)
UA (1) UA86573C2 (de)
WO (1) WO2004000317A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL150509A (en) * 2002-07-01 2007-07-04 Joseph Kaspi Pharmaceutical preparations containing donafazil hydrochloride
IL154370A0 (en) * 2003-02-10 2003-09-17 Chemagis Ltd Solid amorphous mixtures, processes for the preparation thereof and pharmaceutical compositions containing the same
WO2005065645A2 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Donepezil formulations
US8980894B2 (en) 2004-03-25 2015-03-17 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure
EP1579862A1 (de) 2004-03-25 2005-09-28 Boehringer Ingelheim Vetmedica Gmbh Verwendung von PDE III Ihibitoren zur Reduktion der Herzgrösse in an Herzversagen leidenden Säugern
AU2005288521A1 (en) 2004-09-29 2006-04-06 Chemagis Ltd. Use of purified donepezil maleate for preparing pharmaceutically pure amorphous donepezil hydrochloride
EP2039349A1 (de) * 2004-10-19 2009-03-25 KRKA, tovarna zdravil, d.d., Novo mesto Feste pharmazeutische Zusammensetzung mit Donepezilhydrochlorid
WO2006063025A1 (en) * 2004-12-07 2006-06-15 Nektar Therapeutics Stable non-crystalline formulation comprising donepezil
US20060122226A1 (en) 2004-12-08 2006-06-08 Itai Adin Crystalline forms of Donepezil base
CA2592605C (en) 2004-12-27 2010-12-07 Eisai R&D Management Co., Ltd. Method for stabilizing anti-dementia drug
JP2007015934A (ja) * 2005-07-05 2007-01-25 Meiko Shoji Kk 温感クリーム化粧料
DE102005060377A1 (de) 2005-12-16 2007-06-21 Ratiopharm Gmbh Pharmazeutische Zusammensetzung enthaltend Donepezilhydrochlorid, Tablette hieraus und Verfahren zu deren Herstellung
EP1920785A1 (de) 2006-11-07 2008-05-14 Boehringer Ingelheim Vetmedica Gmbh Pimobendan-Cyclodextrin Komplex enthaltendes flüssiges Präparat
DE102007037932A1 (de) 2007-08-11 2009-02-12 Alfred E. Tiefenbacher Gmbh & Co.Kg Donepezilhydrochlorid in amorpher Form enthaltende Tablette
DE102009041839A1 (de) * 2009-09-18 2011-03-24 Dolorgiet Gmbh & Co. Kg Donepezil-haltige Tabletten
EP2366378A1 (de) 2010-03-01 2011-09-21 Dexcel Pharma Technologies Ltd. Donepezilformulierungen mit verzögerter Freisetzung
WO2011151359A1 (en) 2010-06-02 2011-12-08 Noscira, S.A. Combined treatment with a cholinesterase inhibitor and a thiadiazolidinedione derivative
EP2502620A1 (de) 2011-03-24 2012-09-26 Krka Tovarna Zdravil, D.D., Novo Mesto Feste pharmazeutische Zusammensetzung mit Donepezil
US10398705B2 (en) 2012-03-15 2019-09-03 Boehringer Ingelheim Vetmedica Gmbh Pharmaceutical tablet formulation for the veterinary medical sector, method of production and use thereof
AU2014292086B2 (en) 2013-07-19 2019-08-08 Boehringer Ingelheim Vetmedica Gmbh Preserved etherified cyclodextrin derivatives containing liquid aqueous pharmaceutical composition
MX375936B (es) 2013-12-04 2025-03-07 Boehringer Ingelheim Vetmedica Gmbh Composiciones farmaceuticas mejoradas de pimobendan.
US20180344646A1 (en) * 2015-11-25 2018-12-06 Patheon Development Services Inc. Amorphous dispersion granules and oral dosage forms
US10537570B2 (en) 2016-04-06 2020-01-21 Boehringer Ingelheim Vetmedica Gmbh Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease
KR102372630B1 (ko) * 2019-05-15 2022-03-14 주식회사 대웅제약 고함량의 도네페질 또는 그의 염을 포함하는 경피흡수제제

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2525108B1 (fr) * 1982-04-19 1989-05-12 Elan Corp Ltd Medicaments a haut degre de solubilite et procede pour leur obtention
AU731282B2 (en) * 1996-06-07 2001-03-29 Eisai Co. Ltd. Polymorphs of donepezil hydrochloride and process for production
ES2310164T3 (es) * 1999-02-10 2009-01-01 Pfizer Products Inc. Dispositivo de liberacion controlada por la matriz.
EP1175205B1 (de) * 1999-11-12 2006-06-14 Abbott Laboratories Feste dispersion mit ritonavir, fenofibrat oder griseofulvin

Also Published As

Publication number Publication date
SI21223A (sl) 2003-12-31
RS51824B (sr) 2012-02-29
CY1109314T1 (el) 2014-07-02
EA012904B1 (ru) 2010-02-26
HRP20041198A2 (en) 2005-04-30
PL372116A1 (en) 2005-07-11
EP1513528A1 (de) 2005-03-16
PL212584B1 (pl) 2012-10-31
HRP20041198B1 (hr) 2013-05-31
DE60327696D1 (de) 2009-07-02
ES2326529T3 (es) 2009-10-14
RS110604A (sr) 2007-02-05
WO2004000317A1 (en) 2003-12-31
DK1513528T3 (da) 2009-09-07
SI1513528T1 (sl) 2009-10-31
EP1513528B1 (de) 2009-05-20
UA86573C2 (ru) 2009-05-12
AU2003279102A1 (en) 2004-01-06
PT1513528E (pt) 2009-08-18
EA200500040A1 (ru) 2005-06-30

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