ATE432076T1 - Neue methoden und verfahren zur behandlung und vermeidung von ileus - Google Patents
Neue methoden und verfahren zur behandlung und vermeidung von ileusInfo
- Publication number
- ATE432076T1 ATE432076T1 AT00992255T AT00992255T ATE432076T1 AT E432076 T1 ATE432076 T1 AT E432076T1 AT 00992255 T AT00992255 T AT 00992255T AT 00992255 T AT00992255 T AT 00992255T AT E432076 T1 ATE432076 T1 AT E432076T1
- Authority
- AT
- Austria
- Prior art keywords
- ileus
- treating
- methods
- procedures
- new methods
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 6
- 208000008384 ileus Diseases 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000008896 Opium Chemical class 0.000 abstract 1
- 150000003797 alkaloid derivatives Chemical class 0.000 abstract 1
- INAXVFBXDYWQFN-XHSDSOJGSA-N morphinan Chemical class C1C2=CC=CC=C2[C@]23CCCC[C@H]3[C@@H]1NCC2 INAXVFBXDYWQFN-XHSDSOJGSA-N 0.000 abstract 1
- 239000002623 mu opiate receptor antagonist Substances 0.000 abstract 1
- 229960001027 opium Drugs 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45092099A | 1999-11-29 | 1999-11-29 | |
| PCT/US2000/042313 WO2001042207A2 (en) | 1999-11-29 | 2000-11-29 | Novel methods for the treatment and prevention of ileus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE432076T1 true ATE432076T1 (de) | 2009-06-15 |
Family
ID=23790061
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00992255T ATE432076T1 (de) | 1999-11-29 | 2000-11-29 | Neue methoden und verfahren zur behandlung und vermeidung von ileus |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1244448B1 (de) |
| JP (2) | JP5079961B2 (de) |
| AT (1) | ATE432076T1 (de) |
| AU (2) | AU780738B2 (de) |
| CA (1) | CA2393141C (de) |
| CY (1) | CY1109264T1 (de) |
| DE (1) | DE60042282D1 (de) |
| DK (1) | DK1244448T3 (de) |
| ES (1) | ES2329004T3 (de) |
| IL (2) | IL149650A0 (de) |
| MX (1) | MXPA02005336A (de) |
| NZ (1) | NZ518684A (de) |
| PT (1) | PT1244448E (de) |
| WO (1) | WO2001042207A2 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6274591B1 (en) | 1997-11-03 | 2001-08-14 | Joseph F. Foss | Use of methylnaltrexone and related compounds |
| ES2528669T3 (es) | 2003-04-08 | 2015-02-11 | Progenics Pharmaceuticals, Inc. | Formulaciones farmacéuticas que contienen metilnaltrexona |
| US6992090B2 (en) * | 2003-06-16 | 2006-01-31 | Adolor Corporation | Substituted piperidine compounds and methods of their use |
| WO2006096626A2 (en) | 2005-03-07 | 2006-09-14 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
| US9662325B2 (en) | 2005-03-07 | 2017-05-30 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
| US8524731B2 (en) | 2005-03-07 | 2013-09-03 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
| US8518962B2 (en) | 2005-03-07 | 2013-08-27 | The University Of Chicago | Use of opioid antagonists |
| AR057035A1 (es) | 2005-05-25 | 2007-11-14 | Progenics Pharm Inc | SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS |
| AR057325A1 (es) | 2005-05-25 | 2007-11-28 | Progenics Pharm Inc | Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos |
| KR101453107B1 (ko) | 2006-04-21 | 2014-10-27 | 디에스엠 아이피 어셋츠 비.브이. | 오피오이드 수용체 길항제의 용도 |
| TWI489984B (zh) | 2006-08-04 | 2015-07-01 | Wyeth Corp | 用於非經腸道傳輸化合物之配方及其用途 |
| BRPI0809579B8 (pt) | 2007-03-29 | 2021-05-25 | Progenics Pharm Inc | formas cristalinas e seus usos |
| PL2139890T3 (pl) | 2007-03-29 | 2014-11-28 | Wyeth Llc | Antagoniści obwodowych receptorów opioidowych i ich zastosowania |
| PE20090700A1 (es) | 2007-03-29 | 2009-07-13 | Progenics Pharm Inc | Compuestos heterociclicos como antagonistas del receptor opioide periferico |
| WO2009099411A1 (en) | 2008-02-06 | 2009-08-13 | Progenics Pharmaceuticals, Inc. | Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone |
| AU2009225434B2 (en) | 2008-03-21 | 2014-05-22 | The University Of Chicago | Treatment with opioid antagonists and mTOR inhibitors |
| CA2676881C (en) | 2008-09-30 | 2017-04-25 | Wyeth | Peripheral opioid receptor antagonists and uses thereof |
| RU2455943C1 (ru) * | 2011-02-01 | 2012-07-20 | Государственное образовательное учреждение высшего профессионального образования "Российский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО РГМУ Росздрава) | Способ лечения обтурационной формы острой спаечной тонкокишечной непроходимости |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1420015B1 (de) * | 1959-10-16 | 1971-08-26 | Boehringer Sohn Ingelheim | 2'-Hydroxy-5,9-dimethyl-6,7-benzomorphane |
| US4176186A (en) * | 1978-07-28 | 1979-11-27 | Boehringer Ingelheim Gmbh | Quaternary derivatives of noroxymorphone which relieve intestinal immobility |
| FR2514644A1 (fr) * | 1981-10-19 | 1983-04-22 | Sanofi Sa | Composition pharmaceutique a action antagoniste peripherique des opiaces |
| JPS59500418A (ja) * | 1982-03-16 | 1984-03-15 | ザ ロツクフエラ− ユニバ−シテイ | 胃腸能動作用障害を回復する方法 |
| US4806556A (en) * | 1985-12-12 | 1989-02-21 | Regents Of The University Of Minnesota | Gut-selective opiates |
| US4730048A (en) * | 1985-12-12 | 1988-03-08 | Regents Of The University Of Minnesota | Gut-selective opiates |
| US5250542A (en) * | 1991-03-29 | 1993-10-05 | Eli Lilly And Company | Peripherally selective piperidine carboxylate opioid antagonists |
| US6274591B1 (en) | 1997-11-03 | 2001-08-14 | Joseph F. Foss | Use of methylnaltrexone and related compounds |
-
2000
- 2000-11-29 AU AU39705/01A patent/AU780738B2/en not_active Ceased
- 2000-11-29 MX MXPA02005336A patent/MXPA02005336A/es active IP Right Grant
- 2000-11-29 NZ NZ518684A patent/NZ518684A/xx unknown
- 2000-11-29 JP JP2001543508A patent/JP5079961B2/ja not_active Expired - Fee Related
- 2000-11-29 DE DE60042282T patent/DE60042282D1/de not_active Expired - Lifetime
- 2000-11-29 DK DK00992255T patent/DK1244448T3/da active
- 2000-11-29 IL IL14965000A patent/IL149650A0/xx active IP Right Grant
- 2000-11-29 EP EP00992255A patent/EP1244448B1/de not_active Expired - Lifetime
- 2000-11-29 ES ES00992255T patent/ES2329004T3/es not_active Expired - Lifetime
- 2000-11-29 AT AT00992255T patent/ATE432076T1/de not_active IP Right Cessation
- 2000-11-29 PT PT00992255T patent/PT1244448E/pt unknown
- 2000-11-29 WO PCT/US2000/042313 patent/WO2001042207A2/en not_active Ceased
- 2000-11-29 CA CA2393141A patent/CA2393141C/en not_active Expired - Fee Related
-
2002
- 2002-05-14 IL IL149650A patent/IL149650A/en not_active IP Right Cessation
-
2005
- 2005-07-13 AU AU2005203041A patent/AU2005203041B2/en not_active Ceased
-
2009
- 2009-08-05 CY CY20091100828T patent/CY1109264T1/el unknown
-
2012
- 2012-04-16 JP JP2012092605A patent/JP5460771B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2329004T3 (es) | 2009-11-20 |
| IL149650A (en) | 2011-02-28 |
| DK1244448T3 (da) | 2009-08-17 |
| EP1244448A2 (de) | 2002-10-02 |
| DE60042282D1 (de) | 2009-07-09 |
| AU780738B2 (en) | 2005-04-14 |
| NZ518684A (en) | 2003-11-28 |
| IL149650A0 (en) | 2002-11-10 |
| EP1244448B1 (de) | 2009-05-27 |
| CA2393141C (en) | 2013-08-13 |
| JP2003517476A (ja) | 2003-05-27 |
| EP1244448A4 (de) | 2003-06-25 |
| PT1244448E (pt) | 2009-06-30 |
| CY1109264T1 (el) | 2014-07-02 |
| WO2001042207A2 (en) | 2001-06-14 |
| JP5079961B2 (ja) | 2012-11-21 |
| JP5460771B2 (ja) | 2014-04-02 |
| WO2001042207A3 (en) | 2002-05-02 |
| AU2005203041B2 (en) | 2009-01-08 |
| AU3970501A (en) | 2001-06-18 |
| JP2012162560A (ja) | 2012-08-30 |
| MXPA02005336A (es) | 2003-01-28 |
| AU2005203041A1 (en) | 2005-08-04 |
| CA2393141A1 (en) | 2001-06-14 |
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Legal Events
| Date | Code | Title | Description |
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| UEP | Publication of translation of european patent specification |
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| REN | Ceased due to non-payment of the annual fee |