ATE457169T1 - Verbindungen für die behandlung von gewichtsverlust - Google Patents
Verbindungen für die behandlung von gewichtsverlustInfo
- Publication number
- ATE457169T1 ATE457169T1 AT99947762T AT99947762T ATE457169T1 AT E457169 T1 ATE457169 T1 AT E457169T1 AT 99947762 T AT99947762 T AT 99947762T AT 99947762 T AT99947762 T AT 99947762T AT E457169 T1 ATE457169 T1 AT E457169T1
- Authority
- AT
- Austria
- Prior art keywords
- patient
- receptor antagonist
- weight loss
- inhibitor
- administering
- Prior art date
Links
- 230000004580 weight loss Effects 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 230000000694 effects Effects 0.000 abstract 4
- LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical compound O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 229940044551 receptor antagonist Drugs 0.000 abstract 2
- 239000002464 receptor antagonist Substances 0.000 abstract 2
- 208000016261 weight loss Diseases 0.000 abstract 2
- 229930000680 A04AD01 - Scopolamine Natural products 0.000 abstract 1
- PQSUYGKTWSAVDQ-ZVIOFETBSA-N Aldosterone Chemical compound C([C@@]1([C@@H](C(=O)CO)CC[C@H]1[C@@H]1CC2)C=O)[C@H](O)[C@@H]1[C@]1(C)C2=CC(=O)CC1 PQSUYGKTWSAVDQ-ZVIOFETBSA-N 0.000 abstract 1
- PQSUYGKTWSAVDQ-UHFFFAOYSA-N Aldosterone Natural products C1CC2C3CCC(C(=O)CO)C3(C=O)CC(O)C2C2(C)C1=CC(=O)CC2 PQSUYGKTWSAVDQ-UHFFFAOYSA-N 0.000 abstract 1
- 206010006895 Cachexia Diseases 0.000 abstract 1
- 229940123329 Cathepsin B inhibitor Drugs 0.000 abstract 1
- 229940119334 Chymase inhibitor Drugs 0.000 abstract 1
- 229940118365 Endothelin receptor antagonist Drugs 0.000 abstract 1
- STECJAGHUSJQJN-GAUPFVANSA-N Hyoscine Natural products C1([C@H](CO)C(=O)OC2C[C@@H]3N([C@H](C2)[C@@H]2[C@H]3O2)C)=CC=CC=C1 STECJAGHUSJQJN-GAUPFVANSA-N 0.000 abstract 1
- 229940096915 Imidazoline receptor antagonist Drugs 0.000 abstract 1
- STECJAGHUSJQJN-UHFFFAOYSA-N N-Methyl-scopolamin Natural products C1C(C2C3O2)N(C)C3CC1OC(=O)C(CO)C1=CC=CC=C1 STECJAGHUSJQJN-UHFFFAOYSA-N 0.000 abstract 1
- 229960002478 aldosterone Drugs 0.000 abstract 1
- 229940083712 aldosterone antagonist Drugs 0.000 abstract 1
- 239000002170 aldosterone antagonist Substances 0.000 abstract 1
- 239000002876 beta blocker Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003601 chymase inhibitor Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002526 effect on cardiovascular system Effects 0.000 abstract 1
- 239000002308 endothelin receptor antagonist Substances 0.000 abstract 1
- 239000003457 ganglion blocking agent Substances 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 229940127240 opiate Drugs 0.000 abstract 1
- 230000011514 reflex Effects 0.000 abstract 1
- STECJAGHUSJQJN-FWXGHANASA-N scopolamine Chemical compound C1([C@@H](CO)C(=O)O[C@H]2C[C@@H]3N([C@H](C2)[C@@H]2[C@H]3O2)C)=CC=CC=C1 STECJAGHUSJQJN-FWXGHANASA-N 0.000 abstract 1
- 229960002646 scopolamine Drugs 0.000 abstract 1
- 210000002820 sympathetic nervous system Anatomy 0.000 abstract 1
- 229940075420 xanthine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- AIDS & HIV (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Glass Compositions (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Signal Processing For Digital Recording And Reproducing (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9822459.5A GB9822459D0 (en) | 1998-10-15 | 1998-10-15 | Method of treatment |
| GBGB9822458.7A GB9822458D0 (en) | 1998-10-15 | 1998-10-15 | Methods of treatment |
| GBGB9917181.1A GB9917181D0 (en) | 1999-07-23 | 1999-07-23 | Methods of treatment |
| PCT/GB1999/003302 WO2000021509A2 (en) | 1998-10-15 | 1999-10-15 | Methods of treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE457169T1 true ATE457169T1 (de) | 2010-02-15 |
Family
ID=27269516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99947762T ATE457169T1 (de) | 1998-10-15 | 1999-10-15 | Verbindungen für die behandlung von gewichtsverlust |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7417038B1 (de) |
| EP (1) | EP1121111B1 (de) |
| JP (1) | JP2002527378A (de) |
| AT (1) | ATE457169T1 (de) |
| CY (1) | CY1110282T1 (de) |
| DE (1) | DE69942009D1 (de) |
| DK (1) | DK1121111T3 (de) |
| PT (1) | PT1121111E (de) |
| WO (1) | WO2000021509A2 (de) |
Families Citing this family (72)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7417038B1 (en) * | 1998-10-15 | 2008-08-26 | Imperial Innovations Limited | Methods of treating cachexia |
| US7105526B2 (en) | 2002-06-28 | 2006-09-12 | Banyu Pharmaceuticals Co., Ltd. | Benzimidazole derivatives |
| GB0219660D0 (en) | 2002-08-23 | 2002-10-02 | Astrazeneca Ab | Therapeutic use |
| US20040122067A1 (en) * | 2002-12-20 | 2004-06-24 | Lin Zhao | Treatment of chronic heart failure |
| ATE547404T1 (de) | 2003-09-22 | 2012-03-15 | Msd Kk | Piperidinderivate |
| JP4664924B2 (ja) | 2003-12-02 | 2011-04-06 | ウーツェーベー ファルマ ゲーエムベーハー | 中枢神経因性疼痛の治療のためのペプチド化合物の新規使用 |
| GB0403744D0 (en) | 2004-02-20 | 2004-03-24 | Astrazeneca Ab | Chemical process |
| EP1734963A4 (de) | 2004-04-02 | 2008-06-18 | Merck & Co Inc | Verfahren zur behandlung von menschen mit metabolischen und anthropometrischen störungen |
| EP1604655A1 (de) | 2004-06-09 | 2005-12-14 | Schwarz Pharma Ag | Neue Verwendung von Peptidverbindungen zur Behandlung von Trigeminusneuralgie |
| EP1784390A2 (de) | 2004-08-13 | 2007-05-16 | Amgen Inc. | Substituierte benzokondensierte heterozyklen |
| US7528175B2 (en) * | 2004-10-08 | 2009-05-05 | Inverseon, Inc. | Method of treating airway diseases with beta-adrenergic inverse agonists |
| CN101094689B (zh) | 2004-11-01 | 2013-06-12 | 安米林药品有限责任公司 | 治疗肥胖以及肥胖相关疾病和病症的方法 |
| WO2007022123A2 (en) | 2005-08-11 | 2007-02-22 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides with selectable properties |
| WO2006102476A2 (en) * | 2005-03-21 | 2006-09-28 | Vicus Therapeutics Spe 1, Llc | Compositions and methods for ameliorating cachexia |
| US7737155B2 (en) | 2005-05-17 | 2010-06-15 | Schering Corporation | Nitrogen-containing heterocyclic compounds and methods of use thereof |
| BRPI0610580B8 (pt) | 2005-05-30 | 2021-05-25 | Banyu Pharma Co Ltd | composto derivado de piperidina |
| JPWO2007018248A1 (ja) | 2005-08-10 | 2009-02-19 | 萬有製薬株式会社 | ピリドン化合物 |
| EP2330125A3 (de) | 2005-08-11 | 2012-12-12 | Amylin Pharmaceuticals, Inc. | Hybridpolypeptide mit auswählbaren Eigenschaften |
| WO2007024004A1 (ja) | 2005-08-24 | 2007-03-01 | Banyu Pharmaceutical Co., Ltd. | フェニルピリドン誘導体 |
| EP1940842B1 (de) | 2005-09-29 | 2012-05-30 | Merck Sharp & Dohme Corp. | Acylierte spiropiperidinderivate als modulatoren des melanocortin-4-rezeptors |
| JP2009512715A (ja) | 2005-10-21 | 2009-03-26 | ノバルティス アクチエンゲゼルシャフト | レニン阻害剤と抗異脂肪血症剤および／または抗肥満症剤の組み合わせ |
| IE20050723A1 (en) * | 2005-10-28 | 2007-05-30 | Patrick T Prendergast | Anti-mineralocorticoid therapy of infection |
| WO2007144195A2 (en) | 2006-06-15 | 2007-12-21 | Schwarz Pharma Ag | Pharmaceutical composition with synergistic anticonvulsant effect |
| US8173629B2 (en) | 2006-09-22 | 2012-05-08 | Merck Sharp & Dohme Corp. | Method of treatment using fatty acid synthesis inhibitors |
| US20090247560A1 (en) | 2006-09-28 | 2009-10-01 | Banyu Pharmaceutical Co., Ltd. | Diaryl ketimine derivative |
| GB0624282D0 (en) | 2006-12-05 | 2007-01-10 | Cavalla David | Treatment of cachexia |
| JP5319518B2 (ja) | 2007-04-02 | 2013-10-16 | Ｍｓｄ株式会社 | インドールジオン誘導体 |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| MX354786B (es) | 2007-06-04 | 2018-03-21 | Synergy Pharmaceuticals Inc | Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos. |
| EP2264026A4 (de) | 2008-03-06 | 2012-03-28 | Msd Kk | Alkylaminopyridinderivate |
| WO2009119726A1 (ja) | 2008-03-28 | 2009-10-01 | 萬有製薬株式会社 | メラニン凝集ホルモン受容体拮抗作用を有するジアリールメチルアミド誘導体 |
| ES2522968T3 (es) | 2008-06-04 | 2014-11-19 | Synergy Pharmaceuticals Inc. | Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos |
| WO2009149493A1 (en) * | 2008-06-09 | 2009-12-17 | Dimerix Bioscience Pty Ltd | Novel receptor hetero-dimers/-oligomers |
| JPWO2009154132A1 (ja) | 2008-06-19 | 2011-12-01 | Ｍｓｄ株式会社 | スピロジアミン−ジアリールケトオキシム誘導体 |
| AU2009270833B2 (en) | 2008-07-16 | 2015-02-19 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
| RU2392933C2 (ru) * | 2008-07-18 | 2010-06-27 | Учреждение Российской Академии Медицинских Наук Научно-исследовательский институт экспериментальной медицины Северо-западного отделения РАМН (НИИЭМ СЗО РАМН) | Средство, обладающее гиполипидемическими свойствами |
| EP2319841A1 (de) | 2008-07-30 | 2011-05-11 | Msd K.K. | (5-gliedriges)-(5-gliedriges) oder (5-gliedriges)-(6-gliedriges) kondensiertes ringcycloalkylaminderivat |
| CA2732513C (en) | 2008-08-01 | 2017-04-25 | Arca Biopharma, Inc. | Methods and compositions involving (s)-bucindolol |
| EP2348857B1 (de) | 2008-10-22 | 2016-02-24 | Merck Sharp & Dohme Corp. | Neue cyclische benzimidazolderivate als antidiabetika |
| US8329914B2 (en) | 2008-10-31 | 2012-12-11 | Merck Sharp & Dohme Corp | Cyclic benzimidazole derivatives useful as anti-diabetic agents |
| US20110243940A1 (en) | 2008-12-16 | 2011-10-06 | Schering Corporation | Bicyclic pyranone derivatives and methods of use thereof |
| EP2379547A1 (de) | 2008-12-16 | 2011-10-26 | Schering Corporation | Pyridopyrimidinderivate und verfahren zu deren anwendung |
| GB0907350D0 (en) * | 2009-04-29 | 2009-06-10 | Myotec Therapeutics Ltd | Methods |
| JP5602250B2 (ja) | 2010-01-14 | 2014-10-08 | ノバルティス アーゲー | 副腎ホルモン修飾剤の使用 |
| US20120296403A1 (en) | 2010-02-10 | 2012-11-22 | Novartis Ag | Methods and compounds for muscle growth |
| JP2013520502A (ja) | 2010-02-25 | 2013-06-06 | メルク・シャープ・エンド・ドーム・コーポレイション | 有用な抗糖尿病薬である新規な環状ベンズイミダゾール誘導体 |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| SG192941A1 (en) | 2011-02-25 | 2013-09-30 | Merck Sharp & Dohme | Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents |
| KR20130074808A (ko) * | 2011-12-16 | 2013-07-05 | 한올바이오파마주식회사 | 스타틴계 지질저하제에 의한 근육계 부작용의 치료 또는 예방을 위한 로사르탄을 포함하는 약제학적 조성물 |
| RU2015106909A (ru) | 2012-08-02 | 2016-09-27 | Мерк Шарп И Доум Корп. | Антидиабетические трициклические соединения |
| KR20150118158A (ko) | 2013-02-22 | 2015-10-21 | 머크 샤프 앤드 돔 코포레이션 | 항당뇨병 비시클릭 화합물 |
| WO2014139388A1 (en) | 2013-03-14 | 2014-09-18 | Merck Sharp & Dohme Corp. | Novel indole derivatives useful as anti-diabetic agents |
| ES2698363T3 (es) * | 2013-03-14 | 2019-02-04 | Actimed Therapeutics Ltd | Composiciones de oxprenolol para tratar el cáncer |
| AU2014235215A1 (en) | 2013-03-15 | 2015-10-01 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| AU2014235209B2 (en) | 2013-03-15 | 2018-06-14 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists combined with other drugs |
| BR112015030326A2 (pt) | 2013-06-05 | 2017-08-29 | Synergy Pharmaceuticals Inc | Agonistas ultrapuros de guanilato ciclase c, método de fabricar e usar os mesmos |
| EP2832357A1 (de) | 2013-07-29 | 2015-02-04 | Charité - Universitätsmedizin Berlin | Selektive AT2-Rezeptoragonisten zur Verwendung bei der Behandlung von Kachexie |
| WO2015051496A1 (en) | 2013-10-08 | 2015-04-16 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
| KR102431436B1 (ko) | 2014-08-29 | 2022-08-10 | 테스 파마 에스.알.엘. | α-아미노-β-카복시뮤콘산 세미알데히드 데카복실라제의 억제제 |
| EP3419610A4 (de) | 2016-02-26 | 2019-10-16 | Actimed Therapeutics Ltd | S-enantiomer angereicherte zusammensetzungen von betablockern zur behandlung von muskelschwäche |
| WO2018069532A1 (en) | 2016-10-14 | 2018-04-19 | Tes Pharma S.R.L. | Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase |
| US11072602B2 (en) | 2016-12-06 | 2021-07-27 | Merck Sharp & Dohme Corp. | Antidiabetic heterocyclic compounds |
| EP3558298B1 (de) | 2016-12-20 | 2026-03-11 | Merck Sharp & Dohme LLC | Antidiabetische spirochromanverbindungen |
| US10799138B2 (en) | 2018-04-05 | 2020-10-13 | University Of Maryland, Baltimore | Method of administering sotalol IV/switch |
| US11610660B1 (en) | 2021-08-20 | 2023-03-21 | AltaThera Pharmaceuticals LLC | Antiarrhythmic drug dosing methods, medical devices, and systems |
| US10512620B1 (en) | 2018-08-14 | 2019-12-24 | AltaThera Pharmaceuticals, LLC | Method of initiating and escalating sotalol hydrochloride dosing |
| US11696902B2 (en) | 2018-08-14 | 2023-07-11 | AltaThera Pharmaceuticals, LLC | Method of initiating and escalating sotalol hydrochloride dosing |
| US12396970B2 (en) | 2021-08-20 | 2025-08-26 | AltaThera Pharmaceuticals LLC | Anti-arrhythmic compositions and methods |
| US11344518B2 (en) | 2018-08-14 | 2022-05-31 | AltaThera Pharmaceuticals LLC | Method of converting atrial fibrillation to normal sinus rhythm and loading oral sotalol in a shortened time frame |
| AR117122A1 (es) | 2018-11-20 | 2021-07-14 | Tes Pharma S R L | INHIBIDORES DE LA ÁCIDO a-AMINO-b-CARBOXIMUCÓNICO SEMIALDEHÍDO DESCARBOXILASA |
| US10772869B1 (en) | 2019-07-24 | 2020-09-15 | ECI Pharmaceuticals, LLC | Pharmaceutical compositions including carvedilol and methods of using the same |
| GB2593902B (en) | 2020-04-07 | 2022-04-13 | Actimed Therapeutics Ltd | Salt of a pharmaceutical compound |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5541188A (en) * | 1987-09-15 | 1996-07-30 | The Rowett Research Institute | Therapeutic applications of beta-adrenergic agonists |
| CA1337432C (en) | 1988-03-23 | 1995-10-24 | Raymond M. Xhonneux | Method of lowering the blood pressure |
| US6545040B1 (en) * | 1988-03-23 | 2003-04-08 | Janssen Pharmaceutica N.V. | Method of lowering the blood pressure |
| EP0519925A1 (de) * | 1989-11-21 | 1992-12-30 | Sepracor, Inc. | Verwendung von optisch reinem s(-)-atenolol zur behandlung kardiovaskulärer erkrankungen |
| EP0714663A3 (de) | 1994-11-28 | 1997-01-15 | Lilly Co Eli | Potenzierung von Wirkstoffresponz durch Serotonin 1A Rezeptor Antagonisten |
| EP1136078A3 (de) * | 1995-02-10 | 2002-07-24 | G.D. Searle & Co. | Kombination von Angiotensin konvertierendem Enzym Hemmer und eine nebenwirkungsreduzierende Menge von Aldosteron Antagonist |
| JPH0971586A (ja) | 1995-09-07 | 1997-03-18 | Yamanouchi Pharmaceut Co Ltd | 新規な二環性縮合イミダゾール誘導体 |
| AUPO274596A0 (en) | 1996-10-04 | 1996-10-31 | Armstrong, Stuart Maxwell | Method for the treatment of neurological or neuropsychiatric disorders |
| GB9714675D0 (en) | 1997-07-11 | 1997-09-17 | Smithkline Beecham Plc | Novel composition |
| US7417038B1 (en) * | 1998-10-15 | 2008-08-26 | Imperial Innovations Limited | Methods of treating cachexia |
| CZ20022410A3 (cs) * | 2000-01-31 | 2003-08-13 | Pfizer Products Inc. | Benzoanelované heterocyklylové deriváty nikotinamidu užitečné jako selektivní inhibitory isozymů PDE4 |
| ATE409475T1 (de) * | 2001-02-20 | 2008-10-15 | Dinan Timothy Gerard | Behandlung von fibromyalgie mit pindolol |
| JP2008513430A (ja) | 2004-09-17 | 2008-05-01 | ニューロキュア リミテッド | 月経前症候群および月経前不快気分障害の処置のためのピンドロール |
| JP2008514612A (ja) | 2004-09-23 | 2008-05-08 | ミシャロウ、アレクサンダー | 対抗適応を誘発することにより神経伝達物質系を調節する方法 |
| WO2006102476A2 (en) | 2005-03-21 | 2006-09-28 | Vicus Therapeutics Spe 1, Llc | Compositions and methods for ameliorating cachexia |
| JP2009526087A (ja) | 2005-12-22 | 2009-07-16 | アナボレックス， インコーポレイテッド | 悪液質の予防および処置のための組成物および方法 |
| JP2009528289A (ja) | 2006-02-27 | 2009-08-06 | ミシャロウ、アレクサンダー | 対抗適応を誘発することにより神経伝達物質系を調節する方法 |
| AU2007316613B2 (en) | 2006-11-09 | 2013-11-28 | Boehringer Ingelheim International Gmbh | Combination therapy with SGLT-2 inhibitors and their pharmaceutical compositions |
| AU2008240379B2 (en) | 2007-04-24 | 2012-10-04 | Acacia Pharma Limited | Drug combination of beta 2 agonist and a progestin for the treatment of muscle loss |
| WO2009111648A1 (en) | 2008-03-05 | 2009-09-11 | Vicus Therapeutics, Llc | Compositions and methods for mucositis and oncology therapies |
-
1999
- 1999-10-15 US US09/807,558 patent/US7417038B1/en not_active Expired - Fee Related
- 1999-10-15 WO PCT/GB1999/003302 patent/WO2000021509A2/en not_active Ceased
- 1999-10-15 JP JP2000575485A patent/JP2002527378A/ja active Pending
- 1999-10-15 DE DE69942009T patent/DE69942009D1/de not_active Expired - Lifetime
- 1999-10-15 AT AT99947762T patent/ATE457169T1/de active
- 1999-10-15 PT PT99947762T patent/PT1121111E/pt unknown
- 1999-10-15 EP EP99947762A patent/EP1121111B1/de not_active Expired - Lifetime
- 1999-10-15 DK DK99947762.3T patent/DK1121111T3/da active
-
2008
- 2008-08-15 US US12/192,780 patent/US7829596B2/en not_active Expired - Fee Related
-
2010
- 2010-05-10 CY CY20101100408T patent/CY1110282T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000021509A3 (en) | 2000-11-09 |
| DK1121111T3 (da) | 2010-05-31 |
| EP1121111A2 (de) | 2001-08-08 |
| PT1121111E (pt) | 2010-05-17 |
| US20090023639A1 (en) | 2009-01-22 |
| US7417038B1 (en) | 2008-08-26 |
| CY1110282T1 (el) | 2015-01-14 |
| JP2002527378A (ja) | 2002-08-27 |
| DE69942009D1 (de) | 2010-03-25 |
| WO2000021509A2 (en) | 2000-04-20 |
| US7829596B2 (en) | 2010-11-09 |
| EP1121111B1 (de) | 2010-02-10 |
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