ATE433327T1 - Chemisch programmierbare immunität - Google Patents
Chemisch programmierbare immunitätInfo
- Publication number
- ATE433327T1 ATE433327T1 AT00990960T AT00990960T ATE433327T1 AT E433327 T1 ATE433327 T1 AT E433327T1 AT 00990960 T AT00990960 T AT 00990960T AT 00990960 T AT00990960 T AT 00990960T AT E433327 T1 ATE433327 T1 AT E433327T1
- Authority
- AT
- Austria
- Prior art keywords
- molecule
- binding site
- immunity
- human
- sites
- Prior art date
Links
- 230000036039 immunity Effects 0.000 title abstract 2
- 241001465754 Metazoa Species 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 210000000987 immune system Anatomy 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6025—Nucleotides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Residential Or Office Buildings (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17170799P | 1999-12-22 | 1999-12-22 | |
| PCT/US2000/035179 WO2001045734A1 (en) | 1999-12-22 | 2000-12-21 | Chemically-programmable immunity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE433327T1 true ATE433327T1 (de) | 2009-06-15 |
Family
ID=22624828
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00990960T ATE433327T1 (de) | 1999-12-22 | 2000-12-21 | Chemisch programmierbare immunität |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US20030017165A1 (de) |
| EP (1) | EP1242115B1 (de) |
| AT (1) | ATE433327T1 (de) |
| AU (1) | AU3076601A (de) |
| CA (1) | CA2328356A1 (de) |
| DE (1) | DE60042369D1 (de) |
| DK (1) | DK1242115T3 (de) |
| ES (1) | ES2328102T3 (de) |
| WO (1) | WO2001045734A1 (de) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2328356A1 (en) | 1999-12-22 | 2001-06-22 | Itty Atcravi | Recreational vehicles |
| US7645743B2 (en) * | 1999-12-22 | 2010-01-12 | Altermune, Llc | Chemically programmable immunity |
| EP2230249A3 (de) | 2003-02-06 | 2010-12-22 | ChronTech Pharma AB | Antigen/Antikörper oder Ligand/Rezeptor glycosylierter Spezifität Austauscher |
| US7440877B2 (en) * | 2004-03-12 | 2008-10-21 | General Motors Corporation | System and method for morphable model design space definition |
| US20070134259A1 (en) * | 2005-11-21 | 2007-06-14 | David Bundle | Methods and compositions for pharmacologially controlled targeted immunotherapy |
| EP1790358A1 (de) * | 2005-11-23 | 2007-05-30 | Université de Reims Champagne-Ardennes | Proteinkonstrukte designed zum Targeting und Lyse von Zellen |
| JP2010521526A (ja) * | 2007-03-23 | 2010-06-24 | ザ・ガバナーズ・オブ・ザ・ユニバーシティー・オブ・アルバータ | 多価ヘテロ二官能性ポリマーおよびその使用方法 |
| CN102459298A (zh) * | 2009-05-05 | 2012-05-16 | 阿尔特姆恩科技责任有限公司 | 化学可编程免疫 |
| EP3436585B1 (de) | 2016-04-01 | 2022-07-20 | Avidity Biosciences, Inc. | Kras-nukleinsäuren und verwendungen davon |
| WO2017173320A2 (en) | 2016-04-01 | 2017-10-05 | Avidity Biosciences Llc | Myc nucleic acids and uses thereof |
| JP2019513371A (ja) | 2016-04-01 | 2019-05-30 | アビディティー バイオサイエンシーズ エルエルシー | 核酸ポリペプチド組成物とその使用 |
| WO2017173297A1 (en) | 2016-04-01 | 2017-10-05 | Avidity Biosciences Llc | Beta-catenin nucleic acids and uses thereof |
| US20170283795A1 (en) | 2016-04-01 | 2017-10-05 | Avidity Biosciences Llc | Phosphatidylinositol-3-kinase nucleic acids and uses thereof |
| WO2017173301A1 (en) | 2016-04-01 | 2017-10-05 | Avidity Biosciences Llc | Egfr nucleic acids and uses thereof |
| MX2019008199A (es) | 2017-01-06 | 2019-11-25 | Avidity Biosciences Llc | Composiciones de acido nucleico polipeptido y metodos de induccion de la omision de exon. |
| GB201711809D0 (en) | 2017-07-21 | 2017-09-06 | Governors Of The Univ Of Alberta | Antisense oligonucleotide |
| EP3691657A4 (de) | 2017-10-04 | 2021-07-21 | Avidity Biosciences, Inc. | Nukleinsäurepolypeptidzusammensetzungen und verwendungen davon |
| AU2018378812B2 (en) | 2017-12-06 | 2025-05-22 | Avidity Biosciences, Inc. | Compositions and methods of treating muscle atrophy and myotonic dystrophy |
| IL312067B2 (en) | 2018-12-21 | 2025-08-01 | Avidity Biosciences Inc | Anti-transferrin receptor antibodies and uses thereof |
| GB201904534D0 (en) | 2019-04-01 | 2019-05-15 | Centauri Therapeutics Ltd | Novel compounds an therapeutic uses thereof |
| WO2020219820A1 (en) | 2019-04-25 | 2020-10-29 | Avidity Biosciences, Inc. | Nucleic acid compositions and methods of multi-exon skipping |
| CN114375296A (zh) | 2019-06-06 | 2022-04-19 | 艾维迪提生物科学公司 | 核酸多肽组合物及其用途 |
| US12006499B2 (en) | 2019-06-06 | 2024-06-11 | Avidity Biosciences, Inc. | Una amidites and uses thereof |
| WO2021188390A1 (en) | 2020-03-19 | 2021-09-23 | Avidity Biosciences, Inc. | Compositions and methods of treating facioscapulohumeral muscular dystrophy |
| SI4126066T1 (sl) | 2020-03-27 | 2026-04-30 | Avidity Biosciences, Inc. | Sestavki in postopki zdravljenja mišične distrofije |
| CN118265544A (zh) | 2021-09-16 | 2024-06-28 | 艾维迪提生物科学公司 | 治疗面肩肱型肌营养不良的组合物和方法 |
| EP4735602A2 (de) | 2023-06-27 | 2026-05-06 | Atrium Therapeutics, Inc. | Zusammensetzungen und verfahren zur verwendung eines auf prkag2 abzielenden antikörper-oligonukleotid-konjugat-abstrahs |
| AU2024308906A1 (en) | 2023-06-30 | 2026-02-05 | Atrium Therapeutics, Inc. | Compositions and methods of using pln-targeting antibody-oligonucleotide conjugates |
| GB202406865D0 (en) | 2024-05-15 | 2024-06-26 | Centauri Therapeutics Ltd | Novel compounds and therapeutics uses thereof |
| GB202410052D0 (en) | 2024-07-10 | 2024-08-21 | Centauri Therapeutics Ltd | Novel compounds and therapeutic uses thereof |
Family Cites Families (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4169137A (en) * | 1974-12-20 | 1979-09-25 | Block Engineering, Inc. | Antigen detecting reagents |
| IL51667A (en) * | 1977-03-16 | 1979-10-31 | Miles Yeda Ltd | Immunoassay for the determination of a hapten |
| US5017558A (en) * | 1980-01-14 | 1991-05-21 | The Regents Of The University Of California | Synthetic vaccine peptide epitomes of hepatitis B surface antigen |
| US4711955A (en) * | 1981-04-17 | 1987-12-08 | Yale University | Modified nucleotides and methods of preparing and using same |
| US4737453A (en) * | 1984-12-12 | 1988-04-12 | Immunomedics, Inc. | Sandwich immunoassay utilizing a separation specific binding substance |
| US4637459A (en) * | 1985-06-28 | 1987-01-20 | Roussel Louis J | Anti rotational device for down hole hydraulic pumping unit |
| US4940670A (en) * | 1986-01-24 | 1990-07-10 | Rhodes Buck A | Method for compounding and testing patient specific monoclonal antibodies and monoclonal antibody fragments for in vivo use |
| SE452065B (sv) * | 1986-04-11 | 1987-11-09 | Ulf R Nilsson | Antikroppspreparation vars antikroppar er specifika for determinanter i c3 b regionen hos denaturerat humant c3 samt dess anvendning och framstellning |
| DK8189A (da) * | 1988-01-12 | 1989-07-13 | Bunge Australia | Antigen-antistof-konjugater, deres fremstilling og anvendelse |
| US5378815A (en) * | 1989-10-20 | 1995-01-03 | National Research Council Canada | Process for indirect targeted immunocytolysis |
| GB8924438D0 (en) | 1989-10-31 | 1989-12-20 | Hoffmann La Roche | Vaccine composition |
| US5218088A (en) * | 1989-11-02 | 1993-06-08 | Purdue Research Foundation | Process for preparing dithiophosphate oligonucleotide analogs via nucleoside thiophosphoramidite intermediates |
| US6346611B1 (en) * | 1990-06-11 | 2002-02-12 | Gilead Sciences, Inc. | High affinity TGfβ nucleic acid ligands and inhibitors |
| US6280932B1 (en) * | 1990-06-11 | 2001-08-28 | Gilead Sciences, Inc. | High affinity nucleic acid ligands to lectins |
| US5683867A (en) * | 1990-06-11 | 1997-11-04 | Nexstar Pharmaceuticals, Inc. | Systematic evolution of ligands by exponential enrichment: blended SELEX |
| US6331394B1 (en) * | 1991-06-10 | 2001-12-18 | Gilead Sciences, Inc. | Nucleic acid ligands to integrins |
| US6261774B1 (en) * | 1990-06-11 | 2001-07-17 | Gilead Sciences, Inc. | Truncation selex method |
| US5962219A (en) * | 1990-06-11 | 1999-10-05 | Nexstar Pharmaceuticals, Inc. | Systematic evolution of ligands by exponential enrichment: chemi-selex |
| US5637459A (en) * | 1990-06-11 | 1997-06-10 | Nexstar Pharmaceuticals, Inc. | Systematic evolution of ligands by exponential enrichment: chimeric selex |
| US5496938A (en) * | 1990-06-11 | 1996-03-05 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligands to HIV-RT and HIV-1 rev |
| ES2259800T3 (es) * | 1990-06-11 | 2006-10-16 | Gilead Sciences, Inc. | Procedimientos de uso de ligandos de acido nucleico. |
| US6395888B1 (en) * | 1996-02-01 | 2002-05-28 | Gilead Sciences, Inc. | High affinity nucleic acid ligands of complement system proteins |
| US6344321B1 (en) * | 1990-06-11 | 2002-02-05 | Gilead Sciences, Inc. | Nucleic acid ligands which bind to hepatocyte growth factor/scatter factor (HGF/SF) or its receptor c-met |
| US6232071B1 (en) * | 1990-06-11 | 2001-05-15 | Gilead Sciences, Inc. | Tenascin-C nucleic acid ligands |
| US6248332B1 (en) * | 1990-10-05 | 2001-06-19 | Medarex, Inc. | Targeted immunostimulation with bispecific reagents |
| WO1992008491A1 (en) | 1990-11-20 | 1992-05-29 | Tanox Biosystems, Inc. | Conjugates of anti-idiotype antibodies and carriers and their use in epitope-directed immunization |
| WO1995005454A1 (en) | 1992-02-22 | 1995-02-23 | Cambridge Bacteriophage Technologies Ltd. | Engineered bacteriophages and vaccines containing them |
| US6579696B1 (en) * | 1992-12-21 | 2003-06-17 | Promega Corporation | Polymyxin B conjugates |
| US6933366B2 (en) * | 1996-12-27 | 2005-08-23 | Tripep Ab | Specificity exchangers that redirect antibodies to bacterial adhesion receptors |
| US6040137A (en) * | 1995-04-27 | 2000-03-21 | Tripep Ab | Antigen/antibody specification exchanger |
| US6660842B1 (en) * | 1994-04-28 | 2003-12-09 | Tripep Ab | Ligand/receptor specificity exchangers that redirect antibodies to receptors on a pathogen |
| SE9401460D0 (sv) * | 1994-04-28 | 1994-04-28 | Ferring Ab | Antigen/antibody specificity exhanger |
| US6013443A (en) * | 1995-05-03 | 2000-01-11 | Nexstar Pharmaceuticals, Inc. | Systematic evolution of ligands by exponential enrichment: tissue SELEX |
| ATE255910T1 (de) * | 1996-04-10 | 2003-12-15 | Sangstat Medical Corp | Zellmodulierende konjugate aus elementen aus spezifischen bindungspaaren |
| WO1998034957A1 (en) * | 1997-02-11 | 1998-08-13 | Immunomedics, Inc. | STIMULATION OF AN IMMUNE RESPONSE WITH ANTIBODIES LABELED WITH THE α-GALACTOSYL EPITOPE |
| US6140091A (en) * | 1997-06-20 | 2000-10-31 | Boston Biomedical Research Institute | Anti-idiotype vaccines to elicit catalytic antibodies |
| US6054312A (en) * | 1997-08-29 | 2000-04-25 | Selective Genetics, Inc. | Receptor-mediated gene delivery using bacteriophage vectors |
| US7112328B2 (en) * | 1998-07-16 | 2006-09-26 | Vincent Marinkovich | Composition for targeted cell treatment |
| US6423493B1 (en) * | 1998-10-26 | 2002-07-23 | Board Of Regents The University Of Texas System | Combinatorial selection of oligonucleotide aptamers |
| WO2001032207A1 (en) * | 1998-10-30 | 2001-05-10 | United States Army Medical Research And Materiel Command | Methods for conferring active/passive immunotherapy |
| US6329145B1 (en) * | 1999-02-09 | 2001-12-11 | Gilead Science, Inc. | Determining non-nucleic acid molecule binding to target by competition with nucleic acid ligand |
| US6280943B1 (en) * | 1999-06-17 | 2001-08-28 | Gilead Sciences, Inc. | 2′-fluoropyrimidine anti-calf intestinal phosphatase nucleic acid ligands |
| US6387620B1 (en) * | 1999-07-28 | 2002-05-14 | Gilead Sciences, Inc. | Transcription-free selex |
| EP1088889A1 (de) | 1999-10-01 | 2001-04-04 | University Of Cambridge | Rekombinanter doppelt-hybrider filamentöser Bakteriophage |
| WO2001036448A2 (en) | 1999-10-27 | 2001-05-25 | Cel-Sci Corporation | Preparation and composition of peptides useful for treatment of autoimmune and transplant related graft versus host conditions |
| CA2328356A1 (en) | 1999-12-22 | 2001-06-22 | Itty Atcravi | Recreational vehicles |
| US7645743B2 (en) | 1999-12-22 | 2010-01-12 | Altermune, Llc | Chemically programmable immunity |
| CN1441676B (zh) * | 2000-03-31 | 2012-08-22 | 普渡研究基金会 | 用配体-免疫原缀合物治疗的方法 |
| US20030017134A1 (en) * | 2001-06-19 | 2003-01-23 | Technion Research And Development Foundation Ltd. | Methods and pharmaceutical compositions for immune deception, particularly useful in the treatment of cancer |
| US10100316B2 (en) * | 2002-11-21 | 2018-10-16 | Archemix Llc | Aptamers comprising CPG motifs |
-
2000
- 2000-12-14 CA CA002328356A patent/CA2328356A1/en not_active Abandoned
- 2000-12-21 AU AU30766/01A patent/AU3076601A/en not_active Abandoned
- 2000-12-21 DK DK00990960T patent/DK1242115T3/da active
- 2000-12-21 WO PCT/US2000/035179 patent/WO2001045734A1/en not_active Ceased
- 2000-12-21 DE DE60042369T patent/DE60042369D1/de not_active Expired - Lifetime
- 2000-12-21 ES ES00990960T patent/ES2328102T3/es not_active Expired - Lifetime
- 2000-12-21 AT AT00990960T patent/ATE433327T1/de not_active IP Right Cessation
- 2000-12-21 EP EP00990960A patent/EP1242115B1/de not_active Expired - Lifetime
-
2002
- 2002-06-21 US US10/178,046 patent/US20030017165A1/en not_active Abandoned
-
2003
- 2003-10-29 US US10/696,770 patent/US7422746B2/en not_active Expired - Lifetime
-
2006
- 2006-11-30 US US11/606,564 patent/US7850975B2/en not_active Expired - Fee Related
-
2008
- 2008-12-17 US US12/336,746 patent/US8236321B2/en not_active Expired - Fee Related
-
2012
- 2012-07-06 US US13/543,718 patent/US8591910B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US8236321B2 (en) | 2012-08-07 |
| US20070148183A1 (en) | 2007-06-28 |
| US20090142368A1 (en) | 2009-06-04 |
| EP1242115A4 (de) | 2004-06-16 |
| WO2001045734A1 (en) | 2001-06-28 |
| EP1242115B1 (de) | 2009-06-10 |
| US20030017165A1 (en) | 2003-01-23 |
| ES2328102T3 (es) | 2009-11-10 |
| AU3076601A (en) | 2001-07-03 |
| DK1242115T3 (da) | 2009-10-05 |
| CA2328356A1 (en) | 2001-06-22 |
| DE60042369D1 (de) | 2009-07-23 |
| EP1242115A1 (de) | 2002-09-25 |
| US7422746B2 (en) | 2008-09-09 |
| US7850975B2 (en) | 2010-12-14 |
| US20040146515A1 (en) | 2004-07-29 |
| US8591910B2 (en) | 2013-11-26 |
| US20120276136A1 (en) | 2012-11-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1242115 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |