ATE434603T1 - Chinazolinderivate als antivirale mittel - Google Patents

Chinazolinderivate als antivirale mittel

Info

Publication number
ATE434603T1
ATE434603T1 AT06709585T AT06709585T ATE434603T1 AT E434603 T1 ATE434603 T1 AT E434603T1 AT 06709585 T AT06709585 T AT 06709585T AT 06709585 T AT06709585 T AT 06709585T AT E434603 T1 ATE434603 T1 AT E434603T1
Authority
AT
Austria
Prior art keywords
sub
aryl
alkyl
hydroxyalkyl
moiety
Prior art date
Application number
AT06709585T
Other languages
English (en)
Inventor
George Cockerill
Stephen Sean Flack
Neil Mathews
James Iain Salter
Original Assignee
Arrow Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arrow Therapeutics Ltd filed Critical Arrow Therapeutics Ltd
Application granted granted Critical
Publication of ATE434603T1 publication Critical patent/ATE434603T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/61—Carboxylic acid nitriles containing cyano groups and nitrogen atoms being part of imino groups bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT06709585T 2005-01-31 2006-01-30 Chinazolinderivate als antivirale mittel ATE434603T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB0501964.1A GB0501964D0 (en) 2005-01-31 2005-01-31 Chemical compounds
US64956405P 2005-02-04 2005-02-04
US66845605P 2005-04-05 2005-04-05
PCT/GB2006/000294 WO2006079833A1 (en) 2005-01-31 2006-01-30 Quinazoline derivatives as antiviral agents

Publications (1)

Publication Number Publication Date
ATE434603T1 true ATE434603T1 (de) 2009-07-15

Family

ID=34307734

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06709585T ATE434603T1 (de) 2005-01-31 2006-01-30 Chinazolinderivate als antivirale mittel

Country Status (8)

Country Link
US (1) US20080114008A1 (de)
EP (1) EP1844004B1 (de)
JP (1) JP2008528564A (de)
AT (1) ATE434603T1 (de)
DE (1) DE602006007441D1 (de)
ES (1) ES2327778T3 (de)
GB (1) GB0501964D0 (de)
WO (1) WO2006079833A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0520475D0 (en) * 2005-10-07 2005-11-16 Arrow Therapeutics Ltd Chemical compounds
CA2635916A1 (en) * 2006-01-11 2007-07-19 Arrow Therapeutics Limited Triazoloanilinopyrimidine derivatives for use as antiviral agents
WO2008056149A1 (en) * 2006-11-09 2008-05-15 Arrow Therapeutics Limited Quinazoline derivatives and pharmaceutical compositions containing them
KR20100123717A (ko) * 2008-02-12 2010-11-24 브리스톨-마이어스 스큅 컴퍼니 Ｃ형 간염 바이러스 억제제로서의 헤테로시클릭 유도체
WO2010075380A1 (en) 2008-12-23 2010-07-01 Abbott Laboratories Anti-viral compounds
WO2010075376A2 (en) 2008-12-23 2010-07-01 Abbott Laboratories Anti-viral compounds
ES2606717T3 (es) 2009-02-27 2017-03-27 Enanta Pharmaceuticals, Inc. Inhibidores del virus de la hepatitis C
EP2419404B1 (de) 2009-04-15 2015-11-04 AbbVie Inc. Anti virale verbindungen
CN101575319B (zh) * 2009-06-18 2011-07-27 南京医科大学 拉帕替尼合成中间体的制备工艺
US8653070B2 (en) 2009-12-14 2014-02-18 Enanta Pharmaceuticals, Inc. Hepatitis C virus inhibitors
WO2013030750A1 (en) 2011-09-01 2013-03-07 Lupin Limited Antiviral compounds
IN2014MN01547A (de) 2012-02-10 2015-05-08 Lupin Ltd
US20220099637A1 (en) 2018-12-04 2022-03-31 Bristol-Myers Squibb Company Methods of analysis using in-sample calibration curve by multiple isotopologue reaction monitoring

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU741946B2 (en) * 1998-07-20 2001-12-13 Bristol-Myers Squibb Company Substituted benzimidazole antiviral agents
WO2005105761A1 (en) * 2004-04-28 2005-11-10 Arrow Therapeutics Limited Morpholinylanilinoquinazo- line derivatives for use as antiviral agents

Also Published As

Publication number Publication date
US20080114008A1 (en) 2008-05-15
DE602006007441D1 (de) 2009-08-06
WO2006079833A1 (en) 2006-08-03
EP1844004A1 (de) 2007-10-17
EP1844004B1 (de) 2009-06-24
GB0501964D0 (en) 2005-03-09
JP2008528564A (ja) 2008-07-31
ES2327778T3 (es) 2009-11-03

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties