ATE446088T1 - Epigallocatechin-gallate zur hemmung von angiogenese - Google Patents
Epigallocatechin-gallate zur hemmung von angiogeneseInfo
- Publication number
- ATE446088T1 ATE446088T1 AT01900994T AT01900994T ATE446088T1 AT E446088 T1 ATE446088 T1 AT E446088T1 AT 01900994 T AT01900994 T AT 01900994T AT 01900994 T AT01900994 T AT 01900994T AT E446088 T1 ATE446088 T1 AT E446088T1
- Authority
- AT
- Austria
- Prior art keywords
- gallate
- epigallocatechin
- inhibiting angiogenesis
- treatment
- angiogenesis
- Prior art date
Links
- 230000033115 angiogenesis Effects 0.000 title abstract 3
- WMBWREPUVVBILR-WIYYLYMNSA-N (-)-Epigallocatechin-3-o-gallate Chemical compound O([C@@H]1CC2=C(O)C=C(C=C2O[C@@H]1C=1C=C(O)C(O)=C(O)C=1)O)C(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-WIYYLYMNSA-N 0.000 title abstract 2
- WMBWREPUVVBILR-UHFFFAOYSA-N GCG Natural products C=1C(O)=C(O)C(O)=CC=1C1OC2=CC(O)=CC(O)=C2CC1OC(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-UHFFFAOYSA-N 0.000 title abstract 2
- 229940030275 epigallocatechin gallate Drugs 0.000 title abstract 2
- 230000002401 inhibitory effect Effects 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 2
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 abstract 1
- LSHVYAFMTMFKBA-TZIWHRDSSA-N (-)-epicatechin-3-O-gallate Chemical compound O([C@@H]1CC2=C(O)C=C(C=C2O[C@@H]1C=1C=C(O)C(O)=CC=1)O)C(=O)C1=CC(O)=C(O)C(O)=C1 LSHVYAFMTMFKBA-TZIWHRDSSA-N 0.000 abstract 1
- LSHVYAFMTMFKBA-UHFFFAOYSA-N ECG Natural products C=1C=C(O)C(O)=CC=1C1OC2=CC(O)=CC(O)=C2CC1OC(=O)C1=CC(O)=C(O)C(O)=C1 LSHVYAFMTMFKBA-UHFFFAOYSA-N 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 208000000453 Skin Neoplasms Diseases 0.000 abstract 1
- ADRVNXBAWSRFAJ-UHFFFAOYSA-N catechin Natural products OC1Cc2cc(O)cc(O)c2OC1c3ccc(O)c(O)c3 ADRVNXBAWSRFAJ-UHFFFAOYSA-N 0.000 abstract 1
- 235000005487 catechin Nutrition 0.000 abstract 1
- 229950001002 cianidanol Drugs 0.000 abstract 1
- 208000009056 telangiectasis Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/483,952 US6248341B1 (en) | 2000-01-14 | 2000-01-14 | Method of treating topical angiogenesis-related disorders |
| PCT/US2001/001019 WO2001051048A1 (en) | 2000-01-14 | 2001-01-11 | Use of epigallocatechin-gallate for inhibiting angiogenesis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE446088T1 true ATE446088T1 (de) | 2009-11-15 |
Family
ID=23922155
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01900994T ATE446088T1 (de) | 2000-01-14 | 2001-01-11 | Epigallocatechin-gallate zur hemmung von angiogenese |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6248341B1 (de) |
| EP (1) | EP1162968B1 (de) |
| JP (1) | JP2003519654A (de) |
| AT (1) | ATE446088T1 (de) |
| AU (1) | AU781949B2 (de) |
| CA (1) | CA2366621A1 (de) |
| DE (1) | DE60140234D1 (de) |
| ES (1) | ES2332704T3 (de) |
| HK (1) | HK1043052B (de) |
| WO (1) | WO2001051048A1 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6696484B2 (en) | 1997-10-31 | 2004-02-24 | University Of Chicago Office Of Technology And Intellectual Property | Method and compositions for regulation of 5-alpha reductase activity |
| EP1027045A4 (de) * | 1997-10-31 | 2004-12-08 | Arch Dev Corp | Methoden und zusammenstellungen zur regelierung des s-alpha-reduktaseaktivität |
| US7338971B2 (en) * | 2001-08-30 | 2008-03-04 | El-Naggar Mawaheb M | Treatment of inflammatory, cancer, and thrombosis disorders |
| MXPA04004532A (es) | 2001-11-19 | 2004-08-11 | Medigene Ag | Medicamento para el tratamiento de enfermedades tumorales y virales de la piel. |
| US7678549B2 (en) * | 2001-12-28 | 2010-03-16 | Research Development Foundation | Polyphenol inhibition of nucleoside diphosphate kinase-B activity and cancer metastasis |
| US7972632B2 (en) | 2003-02-28 | 2011-07-05 | Unigen Pharmaceuticals, Inc. | Identification of Free-B-Ring flavonoids as potent COX-2 inhibitors |
| US7108868B2 (en) * | 2002-03-22 | 2006-09-19 | Unigen Pharmaceuticals, Inc. | Isolation of a dual cox-2 and 5-lipoxygenase inhibitor from acacia |
| US7260253B2 (en) * | 2002-04-19 | 2007-08-21 | Visiongate, Inc. | Method for correction of relative object-detector motion between successive views |
| BRPI0309689B1 (pt) * | 2002-04-30 | 2021-06-29 | Unigen, Inc | Composições compreendendo uma mistura de flavonóides de anel-b-livre e flavanos e usos das mesmas |
| US8945518B2 (en) * | 2002-04-30 | 2015-02-03 | Unigen, Inc. | Formulation of dual eicosanoid system and cytokine system inhibitors for use in the prevention and treatment of oral diseases and conditions |
| US8034387B2 (en) | 2002-04-30 | 2011-10-11 | Unigen, Inc. | Formulation of a mixture of free-B-ring flavonoids and flavans for use in the prevention and treatment of cognitive decline and age-related memory impairments |
| FR2842102B1 (fr) * | 2002-07-10 | 2005-10-28 | Cep | Utilisation d'un extrait de the pour controler la liberation d'il8, cytokine pro-inflammatoire et son incorporation dans des preparations cosmetiques et/ou dermatologiques |
| PT102931B (pt) * | 2003-03-28 | 2005-08-31 | Univ Do Porto | Utilizacao de bloqueadores da inibicao a longo termo das actividades da atpase na+k+e/ou do trocador na+/h+, na preparacao de um medicamento destinado a terapiaintestinal |
| US20040220119A1 (en) * | 2003-04-04 | 2004-11-04 | Unigen Pharmaceuticals, Inc. | Formulation of dual cycloxygenase (COX) and lipoxygenase (LOX) inhibitors for mammal skin care |
| EP1660109A4 (de) * | 2003-09-02 | 2009-04-08 | Unigen Pharmaceuticals Inc | Formulierung eines gemisches aus freien-b-ring flavonoiden und flavanen zur verwendung bei der prävention und behandlung von kognitiver verschlechterung und altersbedingten gedächtnisstörungen |
| US7910138B2 (en) * | 2003-10-09 | 2011-03-22 | Medigene Ag | Use of a polyphenol for the treatment of a cancerous or precancerous lesion of the skin |
| AU2005265249A1 (en) * | 2004-06-22 | 2006-01-26 | E-L Management Corp. | Dissolvable film composition |
| KR100545304B1 (ko) * | 2004-09-01 | 2006-05-08 | 주식회사 유니젠 | 아선약을 포함하는 운카리아 속 식물, 또는 이의 황금및/또는 녹차의 배합물을 포함하는 사이클로옥시게나제및/또는 5-리폭시게나제 억제용 조성물 |
| US7494809B2 (en) * | 2004-11-09 | 2009-02-24 | Visiongate, Inc. | Automated cell sample enrichment preparation method |
| WO2006135785A2 (en) * | 2005-06-10 | 2006-12-21 | Medical College Of Georgia Research Institute | Compositions and methods for treating immune disorders |
| US9446017B2 (en) | 2005-08-11 | 2016-09-20 | Augusta University Research Institute, Inc. | Compositions and methods for treating herpes simplex virus |
| JP5192380B2 (ja) | 2005-09-08 | 2013-05-08 | 株式會社アモーレパシフィック | 皮膚老化防止用皮膚外用剤組成物 |
| CN102985068B (zh) | 2010-05-18 | 2014-10-22 | 荷兰联合利华有限公司 | 个人护理组合物 |
| JP2021532079A (ja) * | 2018-07-12 | 2021-11-25 | オキュソフト インコーポレイテッドOCuSOFT, Inc. | 目の抗アレルギ用組成物および眼瞼洗浄ワイプ |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS52136909A (en) | 1976-05-06 | 1977-11-16 | Ichirou Yamashita | Preparation of cell activator |
| JP2519024B2 (ja) * | 1982-06-07 | 1996-07-31 | 花王株式会社 | 毛髪化粧料 |
| JPS6281303A (ja) * | 1985-10-01 | 1987-04-14 | Mitsubishi Chem Ind Ltd | 皮膚外用基剤 |
| DE4027350A1 (de) | 1990-08-30 | 1992-03-05 | Karin Omlor | Mittel auf pflanzlicher basis zur regeneration der haut bei frischen brandverletzungen, zur reinigung unreiner haut zur bekaempfung von krampfadern, bei aeusserlicher anwendung |
| DE4138192A1 (de) | 1990-08-30 | 1993-05-27 | Karin Omlor | Mittel auf pflanzlicher basis, zur erneuerung der haut bei frischen brandverletzungen, zur reinigung unreiner haut, zur bekaempfung von krampfadern, zum abklingen von schwellungen bei verletzungen, zum abklingen von schwellungen und juckreiz bei insektenstichen, bei aeusserlicher anwendung |
| JPH05109110A (ja) | 1991-10-16 | 1993-04-30 | Sony Corp | 光学ピツクアツプ装置 |
| US5605929A (en) * | 1992-05-27 | 1997-02-25 | Arch Development Corp. | Methods and compositions for inhibiting 5α-reductase activity |
| JP2691662B2 (ja) | 1992-07-08 | 1997-12-17 | 花王株式会社 | 化粧料 |
| US5391568A (en) * | 1992-07-10 | 1995-02-21 | American Health Foundation | Inhibition of lung tumorigenesis by administration of a polyphenol |
| JPH06172122A (ja) * | 1992-08-31 | 1994-06-21 | Uenoya Honpo:Kk | 化粧品の製造方法 |
| FR2699818B1 (fr) | 1992-12-24 | 1995-02-03 | Oreal | Composition cosmétique ou pharmaceutique contenant en association un polyphénol et un extrait de gingko. |
| JP2764510B2 (ja) | 1992-12-28 | 1998-06-11 | 花王株式会社 | 美白化粧料 |
| US5306486A (en) * | 1993-03-01 | 1994-04-26 | Elizabeth Arden Co., Division Of Conopco, Inc. | Cosmetic sunscreen composition containing green tea and a sunscreen |
| JPH0725742A (ja) | 1993-07-15 | 1995-01-27 | Kao Corp | 美白化粧料 |
| EP0716589A4 (de) * | 1993-07-23 | 1997-06-11 | Morris Herstein | Kosmetische, die hauterneuerung stimulierende zusammensetzung mit langzeit-irritationskontrolle |
| US5670154A (en) | 1994-01-10 | 1997-09-23 | Mitsui Norin Co., Ltd. | Reducing tyrosinase activity |
| GB2293548A (en) | 1994-09-29 | 1996-04-03 | Joan Louise Hibberd | Treatment of herpes infections |
| RU2157695C2 (ru) * | 1995-02-03 | 2000-10-20 | Ле Лабораториз Аетерна Инк. | Экстракты хрящей акулы, способ их получения и применения |
| IT1275905B1 (it) | 1995-03-14 | 1997-10-24 | Indena Spa | Frazioni polifenoliche di te', loro uso e formulazioni che le contengono |
| CA2175985A1 (en) * | 1995-05-10 | 1996-11-11 | Yoichi Kiyosuke | Pharmaceutical composition containing substance inhibiting hsp47 production |
| DE19627344A1 (de) * | 1996-07-01 | 1998-01-08 | Vitasyn Gmbh Entwicklung & Ver | Therapeutisch wirksame bzw. gesundheitsfördernde Zubereitung aus definierten Polyphenolverbindungen |
| JPH10101624A (ja) | 1996-10-01 | 1998-04-21 | Juzo Udaka | ポリアミンの製造法 |
| JPH10175874A (ja) * | 1996-12-19 | 1998-06-30 | Suntory Ltd | 抗アレルギー剤 |
| DE19824727A1 (de) * | 1998-06-03 | 1999-12-09 | Beiersdorf Ag | Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an Catechinen oder einem Gehalt an Extrakt von grünem Tee |
| WO2000000194A1 (en) * | 1998-06-27 | 2000-01-06 | Photogenesis, Inc. | Ophthalmic uses of ppargamma agonists and ppargamma antagonists |
| SE9900473D0 (sv) * | 1999-02-12 | 1999-02-12 | Karolinska Innovations Ab | Inhibitor of endothelial cell proliferation |
-
2000
- 2000-01-14 US US09/483,952 patent/US6248341B1/en not_active Expired - Lifetime
-
2001
- 2001-01-11 ES ES01900994T patent/ES2332704T3/es not_active Expired - Lifetime
- 2001-01-11 HK HK02104512.9A patent/HK1043052B/en not_active IP Right Cessation
- 2001-01-11 AT AT01900994T patent/ATE446088T1/de not_active IP Right Cessation
- 2001-01-11 DE DE60140234T patent/DE60140234D1/de not_active Expired - Lifetime
- 2001-01-11 JP JP2001551472A patent/JP2003519654A/ja active Pending
- 2001-01-11 CA CA002366621A patent/CA2366621A1/en not_active Abandoned
- 2001-01-11 AU AU26392/01A patent/AU781949B2/en not_active Expired
- 2001-01-11 EP EP01900994A patent/EP1162968B1/de not_active Expired - Lifetime
- 2001-01-11 WO PCT/US2001/001019 patent/WO2001051048A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003519654A (ja) | 2003-06-24 |
| HK1043052A1 (en) | 2002-09-06 |
| WO2001051048A1 (en) | 2001-07-19 |
| CA2366621A1 (en) | 2001-07-19 |
| HK1043052B (en) | 2009-12-24 |
| US6248341B1 (en) | 2001-06-19 |
| AU781949B2 (en) | 2005-06-23 |
| DE60140234D1 (de) | 2009-12-03 |
| AU2639201A (en) | 2001-07-24 |
| EP1162968B1 (de) | 2009-10-21 |
| EP1162968A1 (de) | 2001-12-19 |
| ES2332704T3 (es) | 2010-02-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE446088T1 (de) | Epigallocatechin-gallate zur hemmung von angiogenese | |
| EP1446115A4 (de) | Cyanoalkylamino-derivate als protease-hemmer | |
| BRPI0006634B8 (pt) | composição tópica compreendendo extrato de matricária no tratamento e prevenção de distúrbios inflamatórios | |
| NO20033950D0 (no) | N¶rende farmasöytisk preparat omfattende polyfenoler og anvendelse i behandling av kreft | |
| ATE371475T1 (de) | Methoden zur behandlung der hautpigmentierung | |
| PL363168A1 (pl) | Cyklopentanole, kompozycje zawierające takie związki i sposoby leczenia | |
| PT939627E (pt) | Pentafluorobenzenossulfonamidas e analogos | |
| PA8521801A1 (es) | Derivados de ciclopentil-glutaramida como inhibidores de endopeptidasa neutra | |
| PT1115701E (pt) | Ureias de arilsulfonanilida | |
| ATE421877T1 (de) | Verwendung von totarol zur behandlung von pruritus | |
| DE60111362D1 (de) | Stabilisierte ascorbinsäure-lösungen | |
| ATE311871T1 (de) | Verwendung von zinksalzen der konjugierten linoleinsäuren zur behandlung von hautkrankheiten | |
| ATE309995T1 (de) | Substituierte (aminoiminomethyl oder aminomethyl) dihydrobenzofurane und benozopyrane | |
| EA200100141A1 (ru) | Терапевтическая композиция на основе изофлавоноидов для применения в лечении опухолей цитотоксическими агентами | |
| ATE402694T1 (de) | Verwendung von 1-phenyl-3-dimethylamino-propan- verbindungen zur therapie der harninkontinenz | |
| ATE248845T1 (de) | Arylsulfonanilid-phosphate | |
| PT1268463E (pt) | 4-pironas substituidas com arilo e heteroarilo policiclicos uteis para a inibicao selectiva da cascata de coagulacao | |
| PT1259502E (pt) | Analogos biologicamente activos da discodermolida | |
| ATE315387T1 (de) | Verwendung von substituierten 6- dimethylaminomethyl-1-phenyl- cyclohexanverbindungen zur therapie der harninkontinenz | |
| IT1289154B1 (it) | Derivati di isoflavone loro preparazione e loro impiego terapeutico | |
| ATE270895T1 (de) | Topische verwendung von ätherischen ölen zur behandlung von wundheilungsstörungen | |
| DE59908268D1 (de) | Khellin-zubereitung und deren verwendung zur topischen therapie | |
| DE602004016841D1 (de) | Verwendung von 2,2,3,3, tetramethylcyclopropane carbonsäure derivaten zur behandlung von psychiatrischen störungen | |
| BR0111814A (pt) | Composição farmacêutica e produtos que compreende derivados de distamicina acriloìla substituìda, taxanos e/ou antimetabólitos para terapia combinada contra tumores e seu uso | |
| PT1232173E (pt) | Derivados do acido fusidico |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |