ATE447414T1 - Verwendung aktivierter polymere zur trennung von protein- und polypeptid-multimeren - Google Patents
Verwendung aktivierter polymere zur trennung von protein- und polypeptid-multimerenInfo
- Publication number
- ATE447414T1 ATE447414T1 AT06706962T AT06706962T ATE447414T1 AT E447414 T1 ATE447414 T1 AT E447414T1 AT 06706962 T AT06706962 T AT 06706962T AT 06706962 T AT06706962 T AT 06706962T AT E447414 T1 ATE447414 T1 AT E447414T1
- Authority
- AT
- Austria
- Prior art keywords
- separate protein
- activated polymers
- polypeptide multimers
- polypeptide
- separate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05003332 | 2005-02-16 | ||
| PCT/EP2006/001359 WO2006087178A1 (en) | 2005-02-16 | 2006-02-15 | Use of activated polymers for separation of protein and polypeptide multimers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE447414T1 true ATE447414T1 (de) | 2009-11-15 |
Family
ID=36168573
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06706962T ATE447414T1 (de) | 2005-02-16 | 2006-02-15 | Verwendung aktivierter polymere zur trennung von protein- und polypeptid-multimeren |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20080312411A1 (de) |
| EP (1) | EP1848458B1 (de) |
| JP (1) | JP2008530163A (de) |
| AT (1) | ATE447414T1 (de) |
| AU (2) | AU2006215823A1 (de) |
| CA (1) | CA2594666A1 (de) |
| DE (1) | DE602006010176D1 (de) |
| DK (1) | DK1848458T3 (de) |
| ES (1) | ES2335304T3 (de) |
| HR (1) | HRP20090594T1 (de) |
| SI (1) | SI1848458T1 (de) |
| WO (1) | WO2006087178A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2331139B1 (de) * | 2008-09-11 | 2019-04-17 | Nektar Therapeutics | Polymer-alpha-hydroxy-aldehyd und keton-reagenzien und konjugationsverfahren |
| US9315514B2 (en) | 2012-08-27 | 2016-04-19 | Rhodes Technologies | 1,3-dioxanomorphides and 1,3-dioxanocodides |
| EP2931726B1 (de) | 2012-12-14 | 2017-01-25 | Purdue Pharma LP | Spirocyclische morphinane und deren verwendung |
| ES2631197T3 (es) | 2012-12-14 | 2017-08-29 | Purdue Pharma Lp | Análogos de piridonamorfinano y actividad biológica sobre los receptores opiodes |
| US8937084B2 (en) | 2012-12-14 | 2015-01-20 | Purdue Pharma L.P. | Nitrogen containing morphinan derivatives and the use thereof |
| EP2941430B1 (de) | 2012-12-28 | 2017-04-26 | Purdue Pharma LP | 7,8-cyclicmorphinan-analoge |
| CA2896202A1 (en) | 2012-12-28 | 2014-07-03 | Purdue Pharma L.P. | Substituted morphinans and the use thereof |
| WO2014102591A1 (en) | 2012-12-31 | 2014-07-03 | Rhodes Technologies | PROCESS FOR PREPARING 7β-SUBSTITUTED 6α,14α -ETHENOMORPHINANS AND 7β-SUBSTITUTED 6α,14α-ETHANOMORPHINANS |
| US9862726B2 (en) | 2013-12-26 | 2018-01-09 | Purdue Pharma L.P. | Opioid receptor modulating oxabicyclo[2.2.2]octane morphinans |
| WO2015097546A1 (en) | 2013-12-26 | 2015-07-02 | Purdue Pharma L.P. | Propellane-based compounds and their use as opioid receptor modulators |
| WO2015097547A1 (en) | 2013-12-26 | 2015-07-02 | Purdue Pharma L.P. | 10-substituted morphinan hydantoins |
| EP3087078B1 (de) | 2013-12-26 | 2019-05-15 | Purdue Pharma LP | 7-beta-alkyl-analoga von orvinolen |
| WO2015102682A1 (en) | 2013-12-30 | 2015-07-09 | Purdue Pharma L.P. | Pyridone-sulfone morphinan analogs as opioid receptor ligands |
| CN110198945B (zh) | 2016-12-23 | 2023-06-27 | 米尼奥尔克斯治疗有限公司 | 用于制备噻唑烷二酮化合物及其盐的方法 |
| CA3091826A1 (en) | 2018-02-23 | 2019-08-29 | Rhodes Technologies | Novel opioid compounds and uses thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5312808A (en) * | 1989-11-22 | 1994-05-17 | Enzon, Inc. | Fractionation of polyalkylene oxide-conjugated hemoglobin solutions |
| US7052686B2 (en) * | 2000-09-29 | 2006-05-30 | Schering Corporation | Pegylated interleukin-10 |
| WO2003000179A2 (en) * | 2001-06-22 | 2003-01-03 | Pharmacia Corporation | Chemically-modified progenipoietin conjugates |
-
2006
- 2006-02-15 AT AT06706962T patent/ATE447414T1/de active
- 2006-02-15 EP EP06706962A patent/EP1848458B1/de not_active Expired - Lifetime
- 2006-02-15 CA CA002594666A patent/CA2594666A1/en not_active Abandoned
- 2006-02-15 DK DK06706962.5T patent/DK1848458T3/da active
- 2006-02-15 ES ES06706962T patent/ES2335304T3/es not_active Expired - Lifetime
- 2006-02-15 SI SI200630466T patent/SI1848458T1/sl unknown
- 2006-02-15 DE DE602006010176T patent/DE602006010176D1/de not_active Expired - Lifetime
- 2006-02-15 HR HR20090594T patent/HRP20090594T1/hr unknown
- 2006-02-15 AU AU2006215823A patent/AU2006215823A1/en not_active Abandoned
- 2006-02-15 WO PCT/EP2006/001359 patent/WO2006087178A1/en not_active Ceased
- 2006-02-15 US US11/884,300 patent/US20080312411A1/en not_active Abandoned
- 2006-02-15 JP JP2007555522A patent/JP2008530163A/ja not_active Withdrawn
-
2007
- 2007-11-27 AU AU2007237199A patent/AU2007237199A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006215823A1 (en) | 2006-08-24 |
| US20080312411A1 (en) | 2008-12-18 |
| HRP20090594T1 (hr) | 2009-12-31 |
| EP1848458B1 (de) | 2009-11-04 |
| SI1848458T1 (sl) | 2010-01-29 |
| DE602006010176D1 (de) | 2009-12-17 |
| JP2008530163A (ja) | 2008-08-07 |
| EP1848458A1 (de) | 2007-10-31 |
| CA2594666A1 (en) | 2006-08-24 |
| AU2007237199A1 (en) | 2008-01-17 |
| WO2006087178A1 (en) | 2006-08-24 |
| ES2335304T3 (es) | 2010-03-24 |
| DK1848458T3 (da) | 2010-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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