ATE453660T1 - 17-phosphor-steroid-derivate als progesteron- rezeptormodulatoren - Google Patents

17-phosphor-steroid-derivate als progesteron- rezeptormodulatoren

Info

Publication number: ATE453660T1
Authority: AT; Austria
Prior art keywords: phosphorus; steroid derivatives; receptor modulators; progesterone receptor; progesterone
Prior art date: 2006-02-17

Application number

AT07757086T

Other languages

English (en)

Inventor

Weiqin Jiang

Zhihua Sui

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-02-17

Filing date

2007-02-16

Publication date

2010-01-15

2007-02-16 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2010-01-15 Application granted granted Critical

2010-01-15 Publication of ATE453660T1 publication Critical patent/ATE453660T1/de

Links

229910052698 phosphorus Inorganic materials 0.000 title 1
239000011574 phosphorus Substances 0.000 title 1
239000002379 progesterone receptor modulator Substances 0.000 title 1
229940095745 sex hormone and modulator of the genital system progesterone receptor modulator Drugs 0.000 title 1
RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 abstract 2
108090000079 Glucocorticoid Receptors Proteins 0.000 abstract 1
102100033417 Glucocorticoid receptor Human genes 0.000 abstract 1
102100025803 Progesterone receptor Human genes 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
229960003387 progesterone Drugs 0.000 abstract 1
239000000186 progesterone Substances 0.000 abstract 1
108090000468 progesterone receptors Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/36—Antigestagens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/46—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Emergency Medicine (AREA)
Hematology (AREA)
Obesity (AREA)
Gynecology & Obstetrics (AREA)
Pregnancy & Childbirth (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)

AT07757086T 2006-02-17 2007-02-16 17-phosphor-steroid-derivate als progesteron- rezeptormodulatoren ATE453660T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US77504306P	2006-02-17	2006-02-17
PCT/US2007/062274 WO2007098382A2 (en)	2006-02-17	2007-02-16	17-phosphorous steroid derivatives useful as progesterone receptor modulators

Publications (1)

Publication Number	Publication Date
ATE453660T1 true ATE453660T1 (de)	2010-01-15

Family

ID=38330971

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT07757086T ATE453660T1 (de)	2006-02-17	2007-02-16	17-phosphor-steroid-derivate als progesteron- rezeptormodulatoren

Country Status (15)

Country	Link
US (1)	US7671045B2 (de)
EP (1)	EP1989218B1 (de)
JP (1)	JP5230450B2 (de)
CN (1)	CN101421290B (de)
AT (1)	ATE453660T1 (de)
AU (1)	AU2007217095B2 (de)
CA (1)	CA2642566C (de)
CY (1)	CY1111128T1 (de)
DE (1)	DE602007004081D1 (de)
DK (1)	DK1989218T3 (de)
ES (1)	ES2337521T3 (de)
PL (1)	PL1989218T3 (de)
PT (1)	PT1989218E (de)
SI (1)	SI1989218T1 (de)
WO (1)	WO2007098382A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HUP0501132A2 (en) *	2005-12-05	2007-06-28	Richter Gedeon Nyrt	17-alpha-cyanomethyl-17betha-hydroxyestra-4,9-diene-3-one of high purity and process for its production
AU2007217094A1 (en)	2006-02-17	2007-08-30	Janssen Pharmaceutica N.V.	11-phosphorous steroid derivatives useful as progesterone receptor modulators
US7981927B2 (en)	2007-03-07	2011-07-19	Janssen Pharmaceutica N.V.	Steroids derivatives as selective progesterone receptor modulators
CN102617691B (zh) *	2012-01-18	2014-05-14	上海新华联制药有限公司	一种改进的米非司酮中间体制备方法
WO2014060888A1 (en)	2012-10-18	2014-04-24	Lupin Limited	Novel process and intermediate for preparation of ulipristal
US11124537B2 (en)	2015-12-23	2021-09-21	Oric Pharmaceuticals, Inc.	Inhibitors of glucocorticoid receptor
US11110103B2 (en)	2015-12-23	2021-09-07	Oric Pharmaceuticals, Inc.	Inhibitors of glucocorticoid receptor
AU2016379417B2 (en)	2015-12-23	2020-09-24	Oric Pharmaceuticals, Inc.	Inhibitors of glucocorticoid receptor
PT3523315T (pt)	2016-10-07	2021-04-29	Oric Pharmaceuticals Inc	Inibidor de recetor de glucocorticoide
CN106810584A (zh) *	2016-12-28	2017-06-09	宁波第二激素厂	烯丙孕素的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2528434B1 (fr)	1982-06-11	1985-07-19	Roussel Uclaf	Nouveaux 19-nor steroides substitues en 11b et eventuellement en 2, leur procede de preparation et leur application comme medicament
GB9003939D0 (en) *	1990-02-21	1990-04-18	Imperial College	Sulphatase inhibitors
ZA929315B (en) *	1991-12-20	1993-05-24	Akzo Nv	17-spirofuran-3'-ylidene steroids.
CA2100514C (en)	1992-07-29	2005-03-29	Johannes A. M. Hamersma	17-spiromethylene steroids
JPH0995496A (ja) *	1995-09-28	1997-04-08	Kaken Pharmaceut Co Ltd	ウルソデオキシコール酸誘導体
EP1448592B1 (de) *	2001-10-18	2006-03-08	Sterix Limited	Steroidale verbindungen zur inhibierung von steroidsulfatasen

2007
- 2007-02-16 EP EP07757086A patent/EP1989218B1/de not_active Not-in-force
- 2007-02-16 DK DK07757086.9T patent/DK1989218T3/da active
- 2007-02-16 PL PL07757086T patent/PL1989218T3/pl unknown
- 2007-02-16 US US11/675,652 patent/US7671045B2/en not_active Expired - Fee Related
- 2007-02-16 SI SI200730188T patent/SI1989218T1/sl unknown
- 2007-02-16 JP JP2008555504A patent/JP5230450B2/ja not_active Expired - Fee Related
- 2007-02-16 ES ES07757086T patent/ES2337521T3/es active Active
- 2007-02-16 CN CN2007800127744A patent/CN101421290B/zh not_active Expired - Fee Related
- 2007-02-16 AU AU2007217095A patent/AU2007217095B2/en not_active Ceased
- 2007-02-16 PT PT07757086T patent/PT1989218E/pt unknown
- 2007-02-16 AT AT07757086T patent/ATE453660T1/de active
- 2007-02-16 DE DE602007004081T patent/DE602007004081D1/de active Active
- 2007-02-16 WO PCT/US2007/062274 patent/WO2007098382A2/en not_active Ceased
- 2007-02-16 CA CA2642566A patent/CA2642566C/en not_active Expired - Fee Related
2010
- 2010-03-22 CY CY20101100274T patent/CY1111128T1/el unknown

Also Published As

Publication number	Publication date
CY1111128T1 (el)	2015-06-11
ES2337521T3 (es)	2010-04-26
JP5230450B2 (ja)	2013-07-10
AU2007217095A1 (en)	2007-08-30
DK1989218T3 (da)	2010-04-26
CA2642566C (en)	2014-04-15
WO2007098382A2 (en)	2007-08-30
US20070207982A1 (en)	2007-09-06
CA2642566A1 (en)	2007-08-30
CN101421290B (zh)	2012-09-19
EP1989218B1 (de)	2009-12-30
JP2009527490A (ja)	2009-07-30
US7671045B2 (en)	2010-03-02
AU2007217095B2 (en)	2012-05-03
EP1989218A2 (de)	2008-11-12
PT1989218E (pt)	2010-02-01
SI1989218T1 (sl)	2010-04-30
PL1989218T3 (pl)	2010-06-30
WO2007098382A3 (en)	2007-11-01
DE602007004081D1 (de)	2010-02-11
CN101421290A (zh)	2009-04-29

Legal Events

Date

Code

Title

Description

2010-05-15

UEP

Publication of translation of european patent specification

Ref document number: 1989218

Country of ref document: EP

Publication	Publication Date	Title
ATE453660T1 (de)	2010-01-15	17-phosphor-steroid-derivate als progesteron- rezeptormodulatoren
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