ATE455168T1 - Methode zur reinigung von adenoviren - Google Patents

Methode zur reinigung von adenoviren

Info

Publication number
ATE455168T1
ATE455168T1 AT01991967T AT01991967T ATE455168T1 AT E455168 T1 ATE455168 T1 AT E455168T1 AT 01991967 T AT01991967 T AT 01991967T AT 01991967 T AT01991967 T AT 01991967T AT E455168 T1 ATE455168 T1 AT E455168T1
Authority
AT
Austria
Prior art keywords
adenovirus
hydroxyapatite
purifying adenoviruses
adenoviruses
purifying
Prior art date
Application number
AT01991967T
Other languages
English (en)
Inventor
Susan Cannon-Carlson
Collette Cutler
Gary Vellekamp
Marcio Voloch
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE455168T1 publication Critical patent/ATE455168T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4746—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used p53
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351—Methods of production or purification of viral material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Filtering Materials (AREA)
  • Saccharide Compounds (AREA)
AT01991967T 2000-11-29 2001-11-28 Methode zur reinigung von adenoviren ATE455168T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25382300P 2000-11-29 2000-11-29
PCT/US2001/044684 WO2002044348A2 (en) 2000-11-29 2001-11-28 Method for purifying adenoviruses

Publications (1)

Publication Number Publication Date
ATE455168T1 true ATE455168T1 (de) 2010-01-15

Family

ID=22961846

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01991967T ATE455168T1 (de) 2000-11-29 2001-11-28 Methode zur reinigung von adenoviren

Country Status (7)

Country Link
US (2) US20020064860A1 (de)
EP (1) EP1337627B1 (de)
AT (1) ATE455168T1 (de)
AU (1) AU2002232443A1 (de)
DE (1) DE60141081D1 (de)
ES (1) ES2337768T3 (de)
WO (1) WO2002044348A2 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004538005A (ja) 2001-08-08 2004-12-24 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア シアル酸に結合するタンパク質を有するウイルスベクターの精製法
US20070207461A1 (en) 2004-02-23 2007-09-06 Crucell Holland B.V. Virus Purification Methods
US7851218B2 (en) * 2004-12-13 2010-12-14 Schering Corporation Cell lines for production of replication-defective adenovirus
CA2602944C (en) 2005-04-11 2015-08-11 Crucell Holland B.V. Virus purification using ultrafiltration
EP1736538A1 (de) 2005-06-21 2006-12-27 Cytos Biotechnology AG Prozess für die preparative Reinigung von Virus-ähnlichen Partikeln (VLPs)
DE602006019916D1 (de) * 2005-12-12 2011-03-10 Canji Inc Adenovirale expressionsvektoren mit einer expressionskassette im e1-bereich und einer inaktivierten e2b-polymerase
EP2073849B1 (de) * 2006-09-29 2010-11-10 CANJI, Inc. Verfahren und zusammensetzungen für gentherapie
ES2337973B8 (es) 2008-05-16 2011-07-21 Proyecto De Biomedicina Cima, S.L. Adenovirus auxiliares auto-inactivantes para la produccion de adenovirus recombinantes de alta capacidad.
ES2330826B1 (es) 2008-06-04 2010-07-26 Proyecto De Biomedicina Cima, S.L. Sistema para empaquetamiento de adenovirus de alta capacidad.
US10041049B2 (en) 2008-11-03 2018-08-07 Janssen Vaccines & Prevention B.V. Method for the production of adenoviral vectors
JP2011097918A (ja) * 2009-10-07 2011-05-19 Hoya Corp 精製方法およびワクチンの製造方法
CA2777116C (en) 2009-10-15 2020-09-01 Crucell Holland B.V. Process for adenovirus purification from high cell density cultures
JP5393896B2 (ja) 2009-10-15 2014-01-22 クルセル ホランド ベー ヴェー アデノウイルス粒子の精製方法
MX2012007936A (es) 2010-02-15 2012-11-22 Crucell Holland Bv Metodo para la produccion de vectores adenovirales del serotipo 26 del adenovirus.
AR102198A1 (es) 2014-10-09 2017-02-08 Regeneron Pharma Proceso para reducir partículas subvisibles en una formulación farmacéutica
US11020686B2 (en) 2016-08-16 2021-06-01 Regeneron Pharmaceuticals, Inc. Methods for quantitating individual antibodies from a mixture
JP7102401B2 (ja) 2016-10-25 2022-07-19 リジェネロン・ファーマシューティカルズ・インコーポレイテッド クロマトグラフィーデータ解析のための方法およびシステム
CA3073935A1 (en) 2017-09-19 2019-03-28 Regeneron Pharmaceuticals, Inc. Methods of reducing particle formation and compositions formed thereby
TWI853823B (zh) 2018-07-02 2024-09-01 美商里珍納龍藥品有限公司 自混合物製備多肽之系統及方法
EA202192422A1 (ru) 2019-03-05 2021-12-09 Ридженерон Фармасьютикалз, Инк. Человеческий сывороточный альбумин в составах
JP6898535B1 (ja) * 2020-06-16 2021-07-07 ＨＯＹＡ Ｔｅｃｈｎｏｓｕｒｇｉｃａｌ株式会社 アパタイトカラムを使用したウイルスの精製方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2507339B2 (ja) * 1986-08-11 1996-06-12 三井東圧化学株式会社 粗ｔＰＡの精製方法
US5496926A (en) * 1992-01-19 1996-03-05 Yeda Research And Development Co. Ltd. Process of preparing a soluble LDL receptor
JPH07173189A (ja) 1993-12-17 1995-07-11 Masashi Kosakai リガンド存在下で二段階に分けて行うヒドロキシアパタイトクロマトグラフィーの用法
JPH08188599A (ja) 1995-01-09 1996-07-23 Toagosei Co Ltd ＩｇＹ抗体の分離精製方法
US5837520A (en) * 1995-03-07 1998-11-17 Canji, Inc. Method of purification of viral vectors
WO1997008298A1 (en) * 1995-08-30 1997-03-06 Genzyme Corporation Chromatographic purification of adenovirus and aav
JPH09169794A (ja) 1995-12-22 1997-06-30 Mitsubishi Materials Corp 蛋白質類の分離方法
WO1998022588A2 (en) * 1996-11-20 1998-05-28 Introgen Therapeutics, Inc. An improved method for the production and purification of adenoviral vectors
US7732129B1 (en) * 1998-12-01 2010-06-08 Crucell Holland B.V. Method for the production and purification of adenoviral vectors
US6261823B1 (en) * 1996-12-13 2001-07-17 Schering Corporation Methods for purifying viruses
IL137510A0 (en) 1998-02-17 2001-07-24 Schering Corp Compositions comprising viruses and methods for concentrating virus preparations
US6689600B1 (en) * 1998-11-16 2004-02-10 Introgen Therapeutics, Inc. Formulation of adenovirus for gene therapy
JP2000262280A (ja) 1999-03-18 2000-09-26 Asahi Optical Co Ltd ウィルスまたはウィルス性抗原の精製方法およびワクチンの製造方法

Also Published As

Publication number Publication date
AU2002232443A1 (en) 2002-06-11
WO2002044348A3 (en) 2002-11-07
WO2002044348A2 (en) 2002-06-06
EP1337627B1 (de) 2010-01-13
US7393631B2 (en) 2008-07-01
US20060105456A1 (en) 2006-05-18
ES2337768T3 (es) 2010-04-29
EP1337627A2 (de) 2003-08-27
DE60141081D1 (de) 2010-03-04
US20020064860A1 (en) 2002-05-30

Similar Documents

Publication Publication Date Title
ATE455168T1 (de) Methode zur reinigung von adenoviren
DK1075488T3 (da) Proteinoprensning ved ionbytningskromatografi
ATE215611T1 (de) Verfahren zur reinigung, stabilisierung oder isolierung von nukleinsäuren aus biologischen materialien
EP3388452A3 (de) Proteinreinigung
AU2001253808A1 (en) Filter for purifying domestic drinking water
BRPI0410856A (pt) métodos de codificar e de decodificar sinais polifÈnicos, aparelho de codificador, e, sistema de áudio
DE50113146D1 (de) Nukleinsäure-isolierung aus stuhlproben und anderen biologischen materialien, die reich an inhibitoren sind
DE69933186D1 (de) Methode zur Reinigung und Manipulation von Nukleinsäure mittels paramagnetischen Partikeln
ATE451390T1 (de) Polypeptide zur bindung an das b-lymphozyten- stimulatorische protein (blys)
ATE314391T1 (de) Methode zur reinigung von thrombopoietin
DE69920895D1 (de) Verbessertes immundiagnostische tests durch verwendung von reduzierende agenzien
ES2159743T3 (es) Metodo para eliminar constituyentes organicos de una corriente acuosa.
DE60100565D1 (de) Verfahren zur Reinigung von Phosphatidylserin
BR0012422A (pt) Metodo de purificação de água, bactéria adequada para o metodo e uso destes
ATE499943T1 (de) Verwendung von lanthankarbonat zur prävention von nierensteinleiden
SE8601177D0 (sv) Anvendning av hydrofoba zeoliter sasom adsorptionsmaterial vid biologisk rening av avloppsvatten
GR3025944T3 (en) Purification of factor xiii.
EP1351974A4 (de) Gebrauch von viren zum aufspüren oder säubern von proteinen
BR9910715A (pt) Método para a purificação da lipoproteìna ospa de borrelia
FR2794449B1 (fr) Procede d'epuration des liqueurs d'aluminate de sodium contenant de l'oxalate de sodium permettant de valoriser les residus
NO952105L (no) Fremgangsmåte for å fjerne sure forurensninger inneholdt i en vaporisert ström
WO1999051531A8 (en) Waste treatment system and method
ES2177380A1 (es) Procedimiento para la eliminacion de contaminantes biologicos del agua.
FR2838516B1 (fr) Procede de mesure de la teneur en lanthanides dissous dans de l'oxyde d'uranium
RO117586B1 (ro) Compoziţie izotopică pentru soluţii fecundante

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties