ATE464886T1 - Verbessertes transdermales therapeutisches system für die behandlung der parkinson-krankheit - Google Patents

Verbessertes transdermales therapeutisches system für die behandlung der parkinson-krankheit

Info

Publication number
ATE464886T1
ATE464886T1 AT02735338T AT02735338T ATE464886T1 AT E464886 T1 ATE464886 T1 AT E464886T1 AT 02735338 T AT02735338 T AT 02735338T AT 02735338 T AT02735338 T AT 02735338T AT E464886 T1 ATE464886 T1 AT E464886T1
Authority
AT
Austria
Prior art keywords
parkinson
therapeutic system
transdermal therapeutic
disease
treatment
Prior art date
Application number
AT02735338T
Other languages
English (en)
Inventor
Thomas Lauterbach
Dietrich Schacht
Hans-Michael Wolff
Walter Mueller
Original Assignee
Ucb Pharma Gmbh
Lohmann Therapie Syst Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Pharma Gmbh, Lohmann Therapie Syst Lts filed Critical Ucb Pharma Gmbh
Application granted granted Critical
Publication of ATE464886T1 publication Critical patent/ATE464886T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Psychology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
AT02735338T 2001-05-08 2002-05-06 Verbessertes transdermales therapeutisches system für die behandlung der parkinson-krankheit ATE464886T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01111110A EP1256340B1 (de) 2001-05-08 2001-05-08 Verbessertes transdermales therapeutisches System zur Behandlung von Morbus Parkinson
PCT/EP2002/004975 WO2002089777A1 (en) 2001-05-08 2002-05-06 Improved transdermal therapeutic system for the treatment of parkinson's disese

Publications (1)

Publication Number Publication Date
ATE464886T1 true ATE464886T1 (de) 2010-05-15

Family

ID=8177357

Family Applications (2)

Application Number Title Priority Date Filing Date
AT01111110T ATE246919T1 (de) 2001-05-08 2001-05-08 Verbessertes transdermales therapeutisches system zur behandlung von morbus parkinson
AT02735338T ATE464886T1 (de) 2001-05-08 2002-05-06 Verbessertes transdermales therapeutisches system für die behandlung der parkinson-krankheit

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT01111110T ATE246919T1 (de) 2001-05-08 2001-05-08 Verbessertes transdermales therapeutisches system zur behandlung von morbus parkinson

Country Status (17)

Country Link
EP (3) EP1325742A1 (de)
JP (1) JP2004528359A (de)
KR (1) KR100968293B1 (de)
CN (1) CN100457095C (de)
AT (2) ATE246919T1 (de)
AU (1) AU2002310805B8 (de)
CY (1) CY1111880T1 (de)
DE (2) DE60100595T2 (de)
DK (2) DK1256340T3 (de)
ES (2) ES2203563T3 (de)
HK (1) HK1049448B (de)
HU (1) HU229353B1 (de)
PT (2) PT1256340E (de)
RU (1) RU2273477C2 (de)
SI (1) SI1256340T1 (de)
WO (1) WO2002089777A1 (de)
ZA (1) ZA200209980B (de)

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US8246979B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system for the administration of rotigotine
US8246980B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system
DE10234673B4 (de) 2002-07-30 2007-08-16 Schwarz Pharma Ag Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren
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DE10334188B4 (de) 2003-07-26 2007-07-05 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung von Depressionen
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US8815215B2 (en) † 2003-08-15 2014-08-26 Colgate-Palmolive Company Hydrophobic tooth whitening system and methods of use
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DE10359528A1 (de) 2003-12-18 2005-07-28 Schwarz Pharma Ag (S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum
DE10361258A1 (de) * 2003-12-24 2005-07-28 Schwarz Pharma Ag Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson
DE10361259A1 (de) * 2003-12-24 2005-07-28 Schwarz Pharma Ag Verwendung von Rotigotine in einem Frühstadium von Morbus Parkinson zur Prävention des weiteren Neuronenverlustes
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DE102008060203A1 (de) 2008-12-07 2010-06-10 Dietrich Wilhelm Schacht Wirkstoffstabilisierende flächenförmige Vorrichtung
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LT3257504T (lt) 2009-12-22 2024-08-26 UCB Biopharma SRL Polivinilpirolidonas, skirtas nekristalinės formos kietos rotigotino dispersijos stabilizavimui
US8729306B2 (en) 2010-02-05 2014-05-20 Ucb Pharma Gmbh Process for the preparation of nitrogen substituted aminotetralins derivatives
BR112012029944A2 (pt) 2010-06-25 2019-09-24 Ucb Pharma Gmbh processo para preparação de derivados de aminotetralinas substituídas com nitrogênio
CN102475692A (zh) * 2010-11-29 2012-05-30 重庆医药工业研究院有限责任公司 一种防止雷沙吉兰挥发的透皮贴片
EP2559435A1 (de) 2011-08-19 2013-02-20 UCB Pharma GmbH Rotigotin in der Behandlung von Hemineglekt, Schlaganfall und Defiziten nach einem Schlaganfall
CN102499906B (zh) * 2011-10-12 2013-04-17 长春健欣生物医药科技开发有限公司 一种罗替戈汀盐酸盐或自由碱成膜凝胶制剂及其制备方法
DE102012013439A1 (de) 2012-07-03 2014-01-23 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermales therapeutisches System umfassend Rotigotin und Kristallisationsinhibitor
DE102012013421A1 (de) 2012-07-03 2014-01-09 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermales therapeutisches System (TTS) mit Rotigotin
WO2013075823A1 (en) 2011-11-22 2013-05-30 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermal therapeutic system comprising rotigotine and crystallization inhibitor
MX2015000049A (es) * 2012-07-05 2015-04-08 Sk Chemicals Co Ltd Preparacion absorbible transdermicamente que contiene rotigotina.
TW201431570A (zh) 2012-11-22 2014-08-16 Ucb Pharma Gmbh 用於經皮投服羅替戈汀（Ｒｏｔｉｇｏｔｉｎｅ）之多天式貼片
WO2014198422A1 (de) * 2013-06-14 2014-12-18 Tesa Labtec Gmbh Transdermales therapiesystem (tts) mit rotigotin
JP6726096B2 (ja) 2013-07-03 2020-07-22 エルテーエス ローマン テラピー−システメ アーゲー 電子部品を有する経皮治療システム
CN106456566B (zh) * 2014-05-20 2020-06-16 Lts勒曼治疗系统股份公司 含罗替戈汀的经皮递送系统
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CA2948219C (en) 2014-05-20 2023-04-04 Lts Lohmann Therapie-Systeme Ag Method for adjusting the release of active agent in a transdermal delivery system
ES2966170T3 (es) 2020-01-24 2024-04-18 Luye Pharma Switzerland Ag Sistema terapéutico transdérmico que comprende rotigotina y al menos un adhesivo de silicona no resistente a las aminas

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DE19940238A1 (de) * 1999-08-25 2001-03-01 Lohmann Therapie Syst Lts Wirkstoffhaltiges therapeutisches System zur Applikation auf der Haut mit mindestens zwei polymerhaltigen Schichten
EP1256339B1 (de) * 2001-05-08 2003-10-15 Schwarz Pharma Ag Transdermales therapeutisches System für die Erzielung hoher Plasmaspiegel von Rotigotin in der Therapie von Morbus Parkinson

Also Published As

Publication number Publication date
EP1256340A1 (de) 2002-11-13
HK1049448B (en) 2003-12-12
PT1256340E (pt) 2003-12-31
DE60236078D1 (de) 2010-06-02
HUP0302897A3 (en) 2005-02-28
CN1462185A (zh) 2003-12-17
HU229353B1 (en) 2013-11-28
ATE246919T1 (de) 2003-08-15
KR20030025941A (ko) 2003-03-29
CN100457095C (zh) 2009-02-04
EP1256340B1 (de) 2003-08-13
RU2003128642A (ru) 2005-03-27
AU2002310805B8 (en) 2006-01-12
ES2203563T3 (es) 2004-04-16
DK1256340T3 (da) 2003-12-01
ZA200209980B (en) 2003-02-24
KR100968293B1 (ko) 2010-07-07
RU2273477C2 (ru) 2006-04-10
JP2004528359A (ja) 2004-09-16
EP1392256A1 (de) 2004-03-03
PT1392256E (pt) 2010-07-13
EP1325742A1 (de) 2003-07-09
AU2002310805B2 (en) 2005-09-08
HK1049448A1 (en) 2003-05-16
DE60100595D1 (de) 2003-09-18
DE60100595T2 (de) 2004-06-24
SI1256340T1 (en) 2003-12-31
EP1392256B1 (de) 2010-04-21
WO2002089777A1 (en) 2002-11-14
DK1392256T3 (da) 2010-08-02
ES2344782T3 (es) 2010-09-07
CY1111880T1 (el) 2015-11-04
HK1061194A1 (en) 2004-09-10
HUP0302897A2 (hu) 2003-12-29

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